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Gonorrhea: Treatment, Procedure, Cost and Side Effects

What is the treatment? How is the treatment done? Who is eligible for the treatment? (When is the treatment done?) Who is not eligible for the treatment? Are there any side effects? What are the post-treatment guidelines? How long does it take to recover? What is the price of the treatment in India? Are the results of the treatment permanent? What are the alternatives to the treatment?

What is the treatment?

Treatment for gonorrhoea can be done by using oral and injectable antibiotic prescribed by your doctor. It is also important for your sexual partners to be test and treated too even if there are no symptoms evident in him/her. This is because if the partner is also infected but not treated along with you, you might get re-infected. After the patient has been diagnosed with gonorrhoea, decision has to make for whether the patient has to be hospitalised to be treated as an outpatient. Males are always treated as outpatient for their genital infection. But if they come with complications like gonococcal arthritis or gonococcal infection (DGI), hospitalisation would be required. This decision making is q little difficult in females because of high risk of complications. Female with pelvic inflammatory disease (PID) or similar complications are normally avoided by doctor for treatment because of high rate of reinfection, poor follow-up and noncompliance. Gonorrhoea can also be treated by surgical procedures. Patient must not share their medication with another patient with gonorrhoea because the treatments are individual and damage type specific. Re-evaluation might be required if even after the commencement of the treatment, symptoms continue to prevail. Infants may also require medication for conjunctivitis or any other eye disease which may be caused due to the mother’s gonorrhoeal infection.

How is the treatment done?

Gonorrhoea is usually treated with dual therapy of antibiotics- azithromycin (Zmax , Zithromax) or doxycycline(Vibramycin, Monodox) and ceftriaxone. Also, the combination of either injectable gentamicin or oral gemifloxacin (Factive) and oral azithromycin has been proved very effective in the treatment of gonorrhoea. People who are allergic to ceftriaxone (cephalosporin antibiotics) find this combination of treatment beneficial. In the treatment of gonorrhoea, antimicrobial resistance is of growing concern thereby rendering successful treatment difficult. In case of complications like gonococcal arthritis, 1g of ceftriaxone as IV/IM daily coupled with a single dose of 1g azithromycin treatment should be given for a day or two after there has been improvement in the symptoms. The gonococcal conjunctivitis complication in adults can be treated by a single dose of azithromycin 1g PO and ceftriaxone 1g IM along with saline drip. Pelvic inflammatory disease due to gonorrhoea is effectively treated by a single dose of doxycycline 100mg PO BID and ceftriaxone 2g IM for a fortnight in combination with metronidazole 500mg PO BID. Therapy recommended for treating gonococcal epididymitis is a single dose of ceftriaxone 250mg with doxycycline 100mg twice orally every day for 10 consecutive days. For the treatment of gonococcal meningitis and endocarditis, it is advised to use azithromycin 1mg PO as a single dose with ceftriaxone 1-2g IV for every 12 to 24 hours. An alteration in the therapy and its duration must be consulted with your physician, patient’s medical response to the therapy and his/her antimicrobial susceptibility testing must be evaluated with utmost importance. The gonococcal meningitis and endocarditis have been recommended for specific number of days of parenteral therapy, that is, 10-14 days for meningitis and 4 weeks for endocarditis.

Who is eligible for the treatment? (When is the treatment done?)

People who get infected with Neisseria gonorrhoeae bacterium and have symptoms like burning with urination, testicular pain, penile discharge in men and vaginal discharge and bleeding other than in periods with pelvic pain in women are eligible for treatment. Also, the partners of the patients who may not show evident symptoms but might be infected with the bacteria must also go for a diagnostic test and thereafter for its treatment. A child born from a gonorrhoea infected woman may also get infected affecting its eyes developing a condition called ophthalmia neonatorum.

Who is not eligible for the treatment?

Diagnostic test for gonorrhoea must be accompanied by a pregnancy test in women and must be taken care that the treatments and medications are not given to the pregnant women.

Are there any side effects?

Side effects of medication by IV/IM include headache, nausea, pain and reddening of the injection spot and itching. Side effects of oral medications are usually mild abdominal pain, diarrhoea and nausea too. To be more specific, injection of ceftriaxone can cause several side effects like diarrhoea, weakness, pale skin, shortness of breath while exercising, tenderness, pain, warmth or hardness at the injection site. Some serious side effects can also be experienced like stomach ache and tenderness, heartburn, nausea, vomiting, rashes on the body stomach cramps, watery stools with blood, fever, chest pain, painful and decreased urination, pain below the ribs, red, pink, brown or cloudy urine which can also be foul smelling, peeling and blistering of the skin, swelling of the legs, throat, tongue, seizures and difficulty in breathing and swallowing. The gonorrhoea bacterium has grown resistance towards certain drugs like penicillin and tetracyclines.

What are the post-treatment guidelines?

After the treatment is complete you must abstain from sexual contact for at least a week. This will surely reduce the risk of transmission of the disease to your partner. You should also advise your partner(s) to go for gonorrhoea diagnostic test and treatment at the same time. Condoms must be used while having sex or even during oral sex because the bacteria can infect the throat too. If symptoms persist after the treatment, doctor must be consulted soon to prevent the condition to get aggravated. A follow-up treatment done every 2-4 weeks is always good with ‘test of cure’ to be sure that you are completely clear of the bacteria or any sexually transmitted infection.

How long does it take to recover?

It normally takes a week to get rid of the infection completely meanwhile abstaining from sexual activity with your partner. In some cases where the patient suffer from bleeding between the periods, it takes almost another menstrual cycle to get completely rid of the bacteria and improve the bleeding issue.

What is the price of the treatment in India?

The cost of treatment for gonorrhoea can range from Rs.300 to Rs.2000 including consultation fees for the doctor. The STD test can be done for about Rs. 2050.

Are the results of the treatment permanent?

The treatment cannot be termed permanent because re-infection can occur as the transmission of the virus does not just depend upon one person’s hygiene. So, use of protection barriers like condoms must always be used during sexual intercourse to keep infection at bay.

What are the alternatives to the treatment?

Alternative treatment options for gonorrhoea are single dose of cephalosporin injection, cefoxitin or cefotaxime for urogenital and anorectal infections. Cephalosporin allergic patients can get different therapy with a single dose of gemifloxacin PO 320 mg with azithromycin 2g PO. Gentamicin 240 mhg IM with azithromycin 2g PO is also recommended for ones who are allergic to cephalosporin. In case of azithromycin allergy, doxycycline 100 mg PO BID can be prescribed for a week coupled with ceftriaxone.

Popular Questions & Answers

I am 24 years male and I have gonorrhea for the past 6 months I have taken medications with cipralex, doxcyline more than a time in addition with some injections from a drug store and it goes and comes back without I having a sexual intercourse with someone.

MBBS, MS- General Surgery, MCH- Urology, Fellowship Minimal Access Surgery
Urologist, Mumbai
Increasing rates of gonococcal (gc) infection and antimicrobial resistant (amr) gc, are a serious public health concern according to the latest euro-gasp results, 86% of patients with available information on their treatment course received ceftri...

Is azithromycin 500 mg 1x 7 = 7 days enough to treat gonorrhea or it's combination with ceftriaxone etc is also required. If yes, then what should be the ideal dosage of intravenous ceftriaxone along with azithromycin 500 mg tablet and for how many days?

MBBS, MS - Obstetrics and Gynaecology, Fellowship in Day care Gynaecological Endoscopy
Gynaecologist, Kolkata
Hello. According to cdc guideline, regimen for treatment of gonorrhoea is as follow: cdc recommends dual therapy, or using two drugs, to treat gonorrhea a single dose of 250 mg of intramuscular ceftriaxone and 1g of oral azithromycin.

Please I need help urgently, I think i'm going to die. I was diagnosed with gonorrhoea and I started the treatment. An antibiotic injection and flagyl and doxycycline tablets then symptoms persisted and I was told to get flagyl and ofloxacin and after that again symptoms still persisted. All it did was suppress the symptoms and that's all.

Diploma In Family Medicine, M.Sc - Psychotherapy
Sexologist, Pune
Dear Lybrate user. Gonorrhea does not kill anyone instantaneously. May be you should consult some other std specialist and proper treatment. Oflox and flagyl. I think you need to consult a specialist.

Can ceftriaxone 1g be take through veins intravenously (iv) for gonnorehea or should it be taken only intramuscularly I had taken it through veins is it anf or should I take intramuscularly.

MBBS Bachelor of Medicine and Bachelor of Surgery, MS
Gynaecologist, Jaipur
Both routes can be used but IV is preferred 1g ceftriaxone should be dissolved in 3.5 ml of 1% Lidocaine Injection BP. The solution should be administered by deep intramuscular injection. Intramuscular injections should be injected well within the...
1 person found this helpful

A man get his sperm in to his mouth less than 1 drop of his own sperm he have clamadia or gonorrhea then he can have any serious issue.

BASM, MD, MS (Counseling & Psychotherapy), MSc - Psychology, Certificate in Clinical psychology of children and Young People, Certificate in Psychological First Aid, Certificate in Positive Psychology, Positive Psychiatry and Mental Health
Psychologist, Palakkad
Dear user. I can understand. Please don't be panic. The chances are very rare. Still you should consult a physician in person. I am here to help you in every aspect of your mental and physical health. Any sexual or psychological problems can be cu...
1 person found this helpful

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