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Benefits of Iron And Its Side Effects

Last Updated: Apr 25, 2024

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Iron is an essential mineral required for proper growth of the body and maintenance of good health. It is necessary in the production of red blood cells. Majority of iron in the human body is found in myoglobin and hemoglobin. It plays a major role in the carrying of oxygen which is done by the red blood cells. Iron is also an important protein component of metabolism. About 25% of iron is stored in ferritin within the human body. This makes up for future use in case of any deficiencies. Vitamin C helps in the enhanced absorption of iron while abnormal levels of copper, zinc, magnesium, vitamin E, and calcium negatively affect the uptake of iron. Deficiency of iron shows several serious symptoms including fatigue, weakness, anemia, and other skin ailments.

Iron

Iron is mainly supplemented through diet. It is found in both vegetarian and non-vegetarian foods, further classified as heme and non-heme iron. Some of the rich vegetarian sources of iron include legumes, whole grains, sprouts, broccoli, spinach, dry fruits, green leafy vegetables, and cereals. Other non vegetarian sources of iron include chicken liver, seafood, lean red meat, chicken, and eggs.

Nutritional Value of Iron

Iron is a mineral that is required for our bodies to function properly. Most of the iron in our body is found in the blood as hemoglobin, which is a protein used to carry oxygen to the body’s tissues.
There are two types of iron in our diet: heme and non heme iron. Heme iron is derived from the breakdown of hemoglobin and is only found in animal products. Plant-based iron is referred to as non-heme iron.

Health Benefits of Iron

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Mentioned below are the best health benefits of Iron

Hemoglobin formation

Iron is a primary requirement in the formation of hemoglobin, a protein in red blood cells that transport oxygen throughout the body. It also helps in increasing the oxygen carrying capacity of red blood cells. Furthermore, hemoglobin is important in making up for the loss of blood, especially in case of menstruation in women.

Muscle function

Iron is also a major component of muscular tissues, especially myoglobin, which help in providing the required amount of oxygen for contraction of muscles. It helps in maintaining the muscle tone and elasticity.

Brain function

Brain utilizes about 20% of total blood oxygen and its oxygen supply is aided by iron. Brain health and proper functioning can also be related to iron. Proper blood flow and oxygen supply in brain aids in stimulation of the cognitive activity and creates new neural pathways to prevent cognitive disorders, such as Alzheimer’s disease and dementia.

Regulation of body temperature

Iron helps in facilitating regulation of normal body temperature. It has the ability to regulate temperature depending upon the absorption capacity of the body. By maintaining a normal temperature, it also facilitates optimal environment to carryout enzymatic and metabolic functions.

Treats Anemia

It is found to be useful in the treatment of a severe disorder called anemia, which occurs due to loss of blood or deficiency of iron. Iron is also used to supplement women post their pregnancy to compensate for their blood loss.

Boosts Immunity

Iron plays a major role in providing strength to the human immune system, thus making it proficient enough to fight against infections and diseases. Iron helps in providing necessary oxygen to the damaged cells to aid in the process of healing.

Synthesis of neurotransmitters

Iron is one of the key factors in the synthesis of numerous essential neurotransmitters including epinephrine, serotonin, dopamine, and norepinephrine. These chemicals are important in transmitting signals for carrying out different activities involving neurons and brain.

Treatment of fatigue

In cases of unexplained or chronic fatigue, iron supplementation provides necessary cure. Fatigue might be a result of a lack of oxygen supply due to low levels of hemoglobin in the red blood cells.

Restless leg syndrome

Low levels of iron not only causes muscle weakness and muscle spasms but also causes restless leg syndrome. Various studies have shown a low concentration of iron in blood. Proper supplementation of iron helps in curing this condition.

Insomnia

Iron has shown to improve sleeping habits in people suffering from insomnia. It helps in regulating circadian rhythms. It also reduces the fluctuation of blood pressure which is said to keep people awake at night.

Improves concentration

By increasing the supply of oxygen to the brain, iron facilities increase in concentration and cognitive abilities within individuals. It is also found to be helpful in the treatment of children with Attention Deficit Hyperactivity Disorder (ADHD).

Energy metabolism

Iron is one of the primary components of enzymatic systems with the presence of substances, such as cytochromes and catalases. It also plays a major role in energy metabolism.

Uses of Iron

Iron is a metallic chemical element that is found widely in our planet. It has various uses in our daily life. Iron is highly preferred for use, as it is very cheap and available abundantly in the nature. Some of the uses of iron in our life are that of agriculture- iron is an important component in plants. It acts as micronutrients in plants, and deficiency of it can cause various diseases. Iron is also used in foods and medicines. Iron in red blood cells contains haemoglobin. Iron is an important facilitator for regulating body temperature. An interesting fact is that it has the ability to regulate as per the absorption capacity of the body. The need to keep the body temperature stable means that the enzymatic and metabolic functions can happen in their most optimal and efficient environment and temperatures. One of the most important health benefits of iron is that it acts as a carrier of oxygen and thus participates in transferring oxygen from one body cell to other. This is a vital function of iron, as oxygen is required by each and every organ system to perform routine functions. Iron also helps in the treatment of chronic disorders like renal failure anemia, and other chronic diseases of the intestinal and excretory system. These are not related to blood necessarily, like most other iron functions, but remember, iron is still a key part of many necessary processes throughout the body’s systems, not just the circulatory system. Iron plays a key role in providing strength to the immune system of the body. Thus, the body is made proficient enough to fight against a number of diseases and infections. Red blood cells are necessary for providing oxygen to damaged tissues, organs, and cells. Without it, there would be no haemoglobin; without haemoglobin, there would be no oxygen. The healing process needs iron to happen. Iron is an important participant of energy metabolism in the human body. This process is how energy is extracted from the consumed food and subsequently distributed to different body parts. Iron, when consumed in sufficient amounts, can help improve concentration, which will boost the cognitive and mental performance. Increased flow of blood to the brain due to iron’s red blood cell activity is what results in this important benefit. Iron is also useful in treating insomnia in the human body and also improves the sleeping habits and quality of people by regulating their circadian rhythms.

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Side-Effects & Allergies of Iron

Although usually safe for most people, iron is said to cause gastrointestinal disturbances resulting in stomach pain and upset; nausea, vomiting, diarrhea and constipation. It is recommended to be taken on an empty stomach as there are chances that the food consumed can reduce its absorption in the body. However, if iron shows a lot of side effects, it is administered with consumption of food. Administration of higher doses of iron in children is considered as unsafe and results in poisoning. Iron poisoning shows severe conditions, such as low blood pressure, liver failure and intestinal distress. It should be avoided in case of Crohn’s disease or Ulcerative colitis. Essential care must be taken when administering iron to premature infants with marked low levels of vitamin E. Simultaneous administration of iron must be avoided with antibiotics, bisphosphonates, levothyroxine, levodopa, and penicillamine.

Origin And Cultivation of Iron

Although usually safe for most people, iron is said to cause gastrointestinal disturbances resulting in stomach pain and upset; nausea, vomiting, diarrhea and constipation. It is recommended to be taken on an empty stomach as there are chances that the food consumed can reduce its absorption in the body. However, if iron shows a lot of side effects, it is administered with consumption of food. Administration of higher doses of iron in children is considered as unsafe and results in poisoning. Iron poisoning shows severe conditions, such as low blood pressure, liver failure and intestinal distress. It should be avoided in case of Crohn’s disease or Ulcerative colitis. Essential care must be taken when administering iron to premature infants with marked low levels of vitamin E. Simultaneous administration of iron must be avoided with antibiotics, bisphosphonates, levothyroxine, levodopa, and penicillamine.

References

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    Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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    Reviewed ByDt. Ms. Shilpa MarwahB.Sc (Home Science), Post Graduation Diploma in Dietetics and Public Health NutritionDietitian/Nutritionist
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