Get Dettol Kit worth Rs. 130 for just Rs. 4
Common Specialities
{{speciality.keyWord}}
Common Issues
{{issue.keyWord}}
Common Treatments
{{treatment.keyWord}}

Levodopa

Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 14, 2018

Levodopa is an amino acid that is produced and used as a part of the normal biology of human beings, also in some animals and plants. Levodopa crosses the protective blood–brain barrier as dopamine cannot. Thus, Levodopa is used to increase the dopamine concentrations in the treatment of Parkinson's disease and dopamine-responsive dystonia. Besides the central nervous system, Levodopa can also be converted into dopamine from within the peripheral nervous system.

There are two types of responses seen with the administration of Levodopa : The short-duration response which is related to the half-life of the drug. The long-duration response depends directly on the accumulation of effects over at least a two week course, during which ΔFosB accumulates in nigrostriatal neurons. When used in the treatment of Parkinson's disease, this response is seen only in early therapy, as at that stage the inability of the brain to store dopamine is not yet a concern.

Some side effects include hypotension: a result of the dosage being too high, arrhythmias: although this is uncommon, nausea, which can be avoided by taking the drug with food, hair loss, disorientation and, or confusion, an extreme emotional state, particularly anxiety, but also excessive libido.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Neurologist before using this medicine.

In addition to its intended effect, Levodopa may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Neuroleptic malignant syndrome

Panic attacks

Altered behaviour

Mood changes

Altered sleep

Burning sensation of tongue

Confusion

Convulsion

Frequent dreams

Hallucination

Increased sweating

Tachycardia

Irregular heart rate

Tremor

Worsening of tremor

Muscle stiffness.

Is It safe with alcohol?

Syndopa forte tablet may cause excessive drowsiness and calmness with alcohol.

Are there any pregnancy warnings?

Syndopa forte tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Are there any breast-feeding warnings?

Unknown. Human and animal studies are not available. Please consult your doctor.

Is it safe to drive while on this medicine?

Patients who have experienced somnolence and/or an episode of sudden sleep onset must refrain from driving or operating machines.
Advise patients to exercise caution while driving or operating machinery.

Does this affect kidney function?

There is no data available. Please consult doctor before consuming the drug.

Does this affect liver function?

There is no data available. Please consult doctor before consuming the drug.
Below is the list of medicines, which contains Levodopa as ingredient
Corona Remedies Pvt Ltd
Sun Pharmaceutical Industries Ltd
Sun Pharmaceutical Industries Ltd
Sun Pharmaceutical Industries Ltd
Torrent Pharmaceuticals Ltd
Sun Pharmaceutical Industries Ltd
Sun Pharmaceutical Industries Ltd
Intas Pharmaceuticals Ltd
Torrent Pharmaceuticals Ltd
Sun Pharmaceutical Industries Ltd
Sun Pharmaceutical Industries Ltd
Torrent Pharmaceuticals Ltd
Sun Pharmaceutical Industries Ltd
Commonwealth Pharmaceuticals
Intas Pharmaceuticals Ltd
Abbott India Ltd
Sun Pharmaceutical Industries Ltd
Sun Pharmaceutical Industries Ltd
Sun Pharmaceutical Industries Ltd
Levodopa is an amino-acid precursor of dopamine which has antiparkinson properties. Levodopa taken orally crosses the blood-brain barrier and is decarboxylated to dopamine, which is then available to activate dopaminergic receptors. This compensates for the reduced supply of dopamine observed in Parkinson’s disease.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I need to know that what is the action of levodopa how it acts for Parkinson's disease.

FECSM ( spain), Fellow of European Society of Sexual Medicine., School of Sexual Medicine, DPM, MBBS
Sexologist, Bangalore
Basically parkinson's disease is due deficiency of neurotransmitter dopamine. Levodopa gets converter to dopamine in brain and helps parkinson's patients.
1 person found this helpful

Can we take prothaiden tab 25 mg (dothiepin) and syndopa plus (carbidopa + levodopa) together?

B.H.M.S
Homeopath, Patna
Adv 1. Ultrasonography of whole abdomen send report immediately. 2. Syzygium q 5 drop 8 hourly with a glass of water.

What is the most effective treatment for hand tremors, early Parkinson? Is levodopa safe?

MD - Homeopathy, BHMS
Homeopath, Vadodara
It can be best treated by homoeopathy. You can consult me at Lybrate. Till then take zincum met 200 one dose.

My father age is 65 he is suffering from parkinson. His health going down day by day he take levodopa 4 to 6 times in a day. He is also so impatient please suggest how can we care him.

COMT, MPTh/MPT
Physiotherapist, Surat
I understand your concern for your father. In physiotherapy we have several techniques to treat Parkinson’s patients like stretching exercises, manipulation techniques, mobility program, co-ordination/balance training etc. Physical therapy is the ...
2 people found this helpful

Dear Sir, I think I have tremor because my hand is vibration during writing, hold the cup of tea, standing hands against gravity etc. My Father has also same problem. So please suggest me levodopa is right or something else.

MD - Homeopathy, BHMS
Homeopath, Vadodara
Dear Sir,
I think I have tremor because my hand is vibration during writing, hold the cup of tea, standing hands agai...
No never take these Medicines like that.. they are very dangerous.. At this early age you should be very cautious.. Take Homoeopathic treatment..

Popular Health Tips

Suffering From Parkinson's Disease - How You Can Maximise The Effect Of Levodopa?

MBBS, MHS, MD - Neurology (USA), Fellowship In Epilepsy, Clinical Attachment In Movement Disorders
Neurologist, Mumbai
Suffering From Parkinson's Disease - How You Can Maximise The Effect Of Levodopa?
If you are being treated for Parkinson's disease. How can you maximize the effect of Levodopa? The effect of levodopa can be maximized by increasing its absorption from the digestive system. In particular, taking levodopa on an empty stomach is ve...
3016 people found this helpful

All About Parkison's Disease

MBBS, MHS, MD - Neurology (USA), Fellowship In Epilepsy, Clinical Attachment In Movement Disorders
Neurologist, Mumbai
All About Parkison's Disease
* Should I be afraid of talking to the doctor? No. Every doctor wants his/her patient to recover as soon as possible. If patients have the right knowledge, they are able to interpret and report their symptoms better. Having this knowledge prevents...
7 people found this helpful

Parkinson's Disease - What Are The Risk Factors?

M. Ch (Neuro Surgery), MS - General Surgery, MBBS
Neurologist, Gurgaon
Parkinson's Disease - What Are The Risk Factors?
Parkinson s disease is a disorder involving the nervous system. It can start with a mere tremor of one hand and advances to slow movement and stiffness. The face might show little no symptoms in the beginning but the speech might become slurred. W...
1945 people found this helpful

Is There A Test For Self-Assessment For Neurological Disorders?

MBBS, MD - Medicine, DM - Neurology
Neurologist, Gurgaon
Is There A Test For Self-Assessment For Neurological Disorders?
It is very important for any individual suffering from a neurological disorder to take medical assistance. The possible neurological condition can be diagnosed by doing some medical examinations. Some of the examinations that are conducted for dia...
3412 people found this helpful

Oversleeping - Is it a Psychiatric Disorder?

MD - Psychiatry, MBBS
Psychiatrist, Delhi
Oversleeping - Is it a Psychiatric Disorder?
Hyper somnolence or hypersomnia is a condition that leads to constant daytime fatigue and drowsiness as well as prolonged night time sleeps. In this condition, the patient will usually go through repeated bouts of sleep, which he or she will not b...
3686 people found this helpful
Table of Content
About Levodopa
When is Levodopa prescribed?
What are the side effects of Levodopa ?
Key highlights of Levodopa
Medicines containing Levodopa
How does medicine works?