Lybrate Logo
Get the App
For Doctors
Login/Sign-up
tab_logos
About
tab_logos
Feed
Overview

Onoff 200 MG Suspension

Manufacturer :  Ranbaxy Laboratories Ltd
Medicine Composition :  Ofloxacin
Prescription vs OTC : Prescription by Doctor required

About Onoff 200 MG Suspension

Onoff 200 MG Suspension is an antibiotic drug that fights against bacterial infections. It is used in the treatment of infections that are caused by bacteria, such as chronic bronchitis, pneumonia, tuberculosis, gonorrhea, Chlamydia, anthrax and plague.

This medication works by inhibiting the production of certain enzymes in the DNA of a bacteria, which are necessary for the survival and growth of this bacterial infection. Therefore, this antibiotic drug fights against bacterial infections by killing the bacteria and inhibiting the process of bacterial cell division.

Onoff 200 MG Suspension is an antibiotic medicine that kills bacteria and hinders their growth. This antibiotic is a part of a class of drugs called fluoroquinolones, which work to treat infections that have been caused by bacteria. It is highly effective in treating conditions such as infectious diarrhea, cellulitis, prostatitis, plague, pneumonia and tuberculosis.

This medication fights against both Gram-negative as well as Gram-positive bacteria. It damages double stranded bacterial DNA and hinders DNA relaxation, thus inhibiting the synthesis of bacterial DNA. In this way, Onoff 200 MG Suspension inhibits the process of cell division for bacterial DNA, which helps you to get rid of a bacterial infection.

Onoff 200 MG Suspension is available in the form of tablets or capsules that are taken orally, in the form of eye or ear drops, and can also be injected intravenously. It is advisable to take this medication only under the strict guidelines of your doctor.

Follow this prescription until the course is complete, even if the symptoms disappear. You should not skip a dose and avoid taking an extra tablet to make up for it.

It is possible for some people to experience a few common side effects from taking Onoff 200 MG Suspension like headaches, diarrhea, nausea, vomiting, trouble sleeping and dry mouth. These side effects are minor and may not require medical attention, unless they persist for over a week.

However, there are certain severe side effects such as hallucinations, tendonitis, mood swings, anxiety, irregular heartbeat, fatigue and a numbing sensation of the feet or hands. Not everyone experiences these side effects, it occurs only in a few cases. If you do experience any of these side effects, seek medical help immediately.

If you are allergic to Onoff 200 MG Suspension, you might experience symptoms such as itchiness, swollen tongue, face, throat, hands or feet, trouble breathing and rashes. You should stop taking this medicine as soon as you manifest any of these symptoms and contact your doctor immediately.

Some people are more likely to face harmful side effects, if they also suffer from other conditions like brain disorders, seizures, heart conditions, kidney problems, myasthenia gravis, liver disease, epilepsy, tendonitis, an antibiotic allergy, bone disorders and problems of the joints.

It is advisable to inform your doctor of these conditions beforehand if he/she recommends taking Onoff 200 MG Suspension. It is advisable for pregnant women, women who are breastfeeding, and children below 16 years, to avoid taking this antibiotic since it can lead to harmful consequences.

Symptoms of Onoff 200 MG Suspension overdose include acute renal failure, seizures, nausea, vomiting. Treatment includes GI decontamination, if possible, and supportive care.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the uses of Onoff 200 MG Suspension

    • Pneumonia

      Ofloxacin is used in the treatment of Community-Acquired Pneumonia which is a most common type of lung infection caused by Streptococcus pneumoniae, Haemophilus influenzae.

    • Bronchitis

      Ofloxacin is used in the treatment of bronchitis which is an inflammation in lungs caused by Streptococcus pneumonia, Haemophilus influenza, and some Mycoplasma Pneumonia.

    • Pyelonephritis

      Ofloxacin is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumonia.

    • Cystitis

      Ofloxacin is used in the treatment of cystitis which is a bladder infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumonia.

    • Prostatitis

      Ofloxacin is used in the treatment of Prostatitis (inflammation of the prostate gland that produces semen) caused by Escherichia coli, Pseudomonas and Enterococcus species.

    • Gonococcal Infection

      Ofloxacin is used in the treatment of Gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.

    • Joint Infection

      Ofloxacin is used in the treatment of bone and joint infections caused by Enterobacter cloacae, Pseudomonas aeruginosa.

    • Pneumonia With Cystic Fibrosis

      Ofloxacin is used in the treatment of Pneumonia with Cystic Fibrosis (an inherited disease that causes thick mucus to build up in the lungs and promotes the growth of bacteria like Staphylococcus aureus and Hemophilus influenza).

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the contraindications of Onoff 200 MG Suspension ?

    • Allergy

      Avoid taking Ofloxacin if you have a known allergy to this medicine or any other medicines belonging to the class fluoroquinolones.

    • Tendinitis Or Tendon Rupture

      Avoid taking this medicine if you have a past history of tendinitis or tendon rupture after using Ofloxacin.

    • Myasthenia Gravis

      Avoid taking this medicine if you have a past or family history of suffering from Myasthenia Gravis (weakness and rapid fatigue of muscles under voluntary control).

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the side effects of Onoff 200 MG Suspension ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Key highlights of Onoff 200 MG Suspension

    • How long is the duration of effect?

      The effect of this medicine lasts for a duration of 12 to 20 hours.

    • What is the onset of action?

      The peak effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

    • Are there any pregnancy warnings?

      Use of this medicine is not recommended in pregnant women. Use only if clearly needed under the supervision of the doctor.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      Use of this medicine is not recommended in women who breastfeed due to the adverse effect on development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Avoid breastfeeding for about 3 to 4 hours to decrease the infant's risk exposure. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

    • Is It safe with alcohol?

      It is found to be unsafe to consume Onoff 200 MG Suspension along with alcohol.

    • Is it safe to drive while on this medicine?

      This medicine affects the alertness of the patient taking it. Do not drive if you feel dizzy.

    • Does this affect kidney function?

      Caution must be taken in patients with kidney disease. Adjustment of dose might be needed. Kindly consult your doctor before taking this medication.

    • Does this affect liver function?

      Caution must be taken in patients with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking this medication.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the substitutes for Onoff 200 MG Suspension ?

    Below is the list of medicines, which have the same composition, strength and form as Onoff 200 MG Suspension , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    Where is the Onoff 200 MG Suspension approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

    How does this medication work?

    This medicine belongs to the class fluoroquinolones. It works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.

      What are the interactions of Onoff 200 MG Suspension ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        It cause prolongation of prothrombin time. Also elevation in serum triglycerides, cholesterol, potassium, liver function tests are reported.
      • Interaction with Medicine

        • Decreased effect: Decreased absorption with antacids containing aluminium, magnesium, and/or calcium (by up to 98% if given at the same time), iron, vitamins with minerals, mineral supplements, sucralfate, or didanosine; fluoroquinolones may be decreased by antineoplastic agents.
        • Increased toxicity/serum levels: Quinolones cause increased caffeine, warfarin, cyclosporine, procainamide, and possibly theophylline levels. Cimetidine and probenecid increase quinolone levels.
      • Interaction with Disease

        Central Nervous System Depression

        If you suffer from CNS disorder and you take Onoff 200 MG Suspension, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine containing products like coffee, chocolates and energy drinks.

        Colitis

        Avoid taking Onoff 200 MG Suspension if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

        Qt Prolongation

        Avoid using Onoff 200 MG Suspension if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.
      • Interaction with Food

        Dairy products

        The desired effect of Onoff 200 MG Suspension is not observed if consumed with dairy products. There should be at least 2 hours gap between taking Onoff 200 MG Suspension and dairy products.

      FAQs about Onoff 200 MG Suspension

      • Ques : What is Onoff 200 MG Suspension?

        Ans : This medicine belongs to the class of antibacterial. It is primarily prescribed to treat bacterial infections like Pneumonia, Bronchitis, Pyelonephritis, Cystitis, Prostatitis, Joint Infection, etc.

      • Ques : How long do I need to use Onoff 200 MG Suspension before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Onoff 200 MG Suspension?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Onoff 200 MG Suspension empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Onoff 200 MG Suspension?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : Will Onoff 200 MG Suspension work for treating cold and flu?

        Ans : This antibiotic medicine only treats bacterial infections. It will not work for viral infections such as common cold, flu.

      • Ques : Can I stop Onoff 200 MG Suspension if symptoms disappear?

        Ans : Consume this medication until the date it is prescribed, even if symptoms disappear after a few days. Stopping the medication too early may result in a return of the infection.

      • Ques : Does Onoff 200 MG Suspension make the skin more sensitive?

        Ans : This medication may make you sensitive to the sun. Therefore, it is advised to avoid tanning booths and sunlamps. Use sunscreen & wear protective clothing while going out. Also, discuss with your doctor if you get sunburned or have skin blisters/redness.

      • Ques : Can the use of Onoff 200 MG Suspension cause diarrhea?

        Ans : Yes, this medication can cause diarrhea. It is an antibiotic that kills harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.

      • Ques : Can I stop taking Onoff 200 MG Suspension when I feel better?

        Ans : No, do not stop taking this medication and complete the full course of treatment even if you feel better.

      References

      • Ofloxacin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ofloxacin

      • OFLOXACIN- ofloxacin solution/ drops- Daily Med [Internet]. dailymed.nlm.nih.gov. 2020 [Cited 25 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef145ece-56d8-4dea-a136-ec462b335641

      • Tarivid IV Infusion Solution- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 25 Nov 2021]. Available from:

        https://www.medicines.org.uk/emc/product/1668/smpc

      • Ofloxacin- Drug Information Portal [Internet]. druginfo.nlm.nih.gov. 2021 [Cited 25 Nov 2021]. Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ofloxacin

      • OFLOXACIN- ofloxacin solution/ drops- Daily Med [Internet]. dailymed.nlm.nih.gov. 2020 [Cited 25 Nov 2021]. Available from:

        https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ef145ece-56d8-4dea-a136-ec462b335641

      • Tarivid IV Infusion Solution- EMC [Internet]. www.medicines.org.uk. 2021 [Cited 25 Nov 2021]. Available from:

        https://www.medicines.org.uk/emc/product/1668/smpc

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
      swan-banner
      Sponsored

      Popular Questions & Answers

      View All

      From few days I am having on/off itching on for...

      related_content_doctor

      Dr. Gulnar Mufti

      General Physician

      Hi maintain hygiene keep the area dry n clean if you are sexually active rule out any sexually tr...

      I'm having acne problem on/off since 6 yrs. I'v...

      related_content_doctor

      Dr. Sajeev Kumar

      Cardiologist

      Hello, as you are worried and have tried many commercial products which do more harm than good, t...

      I am 42 hrs old female and have pain in my ribs...

      related_content_doctor

      Dr. Akshay Kumar Saxena

      Orthopedist

      Hi thanks for your query and welcome to lybrate. I am Dr. Akshay from fortis hospital, new delhi....

      I feel a vague/ minor discomfort in right lower...

      related_content_doctor

      Dr. M S Haque

      Sexologist

      Testicular pain can be caused by sudden injury, inflammation, sexually transmitted infections or ...

      As she is getting cough and sneezing. ON/OFF fr...

      related_content_doctor

      Dr. Jatin Soni

      General Physician

      It's not serious but we have to treat it and apart from taking symptomatic treatment take a flow ...

      Table of content

      Content Details
      Profile Image
      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
      Profile Image
      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
      chat_icon

      Ask a free question

      Get FREE multiple opinions from Doctors

      posted anonymously
      swan-banner