Get Dettol Kit worth Rs. 130 for just Rs. 4
Common Specialities
{{speciality.keyWord}}
Common Issues
{{issue.keyWord}}
Common Treatments
{{treatment.keyWord}}

Ofloxacin

Prescription vs.OTC: Prescription by Doctor required

Ofloxacin is an antibiotic drug that fights against bacterial infections. It is used in the treatment of infections that are caused by bacteria, such as chronic bronchitis, pneumonia, tuberculosis, gonorrhea, Chlamydia, anthrax and plague. This anti-biotic also treats bacterial infections of the skin, ears, eyes, sinus, pelvis, urinary tract, bladder, cervix, urethra and the respiratory system.

Ofloxacin inhibits the production of certain enzymes in the DNA of a bacteria, which are necessary for the survival and growth of this bacterial infection. Therefore, this antibiotic drug fights against bacterial infections by killing the bacteria and inhibiting the process of bacterial cell division.

Ofloxacin is an antibiotic medicine that kills bacteria and hinders their growth. This antibiotic is a part of a class of drugs called fluoroquinolones, which work to treat infections that have been caused by bacteria. It is highly effective in treating conditions such as infectious diarrhea, cellulitis, prostatitis, plague, pneumonia and tuberculosis. Ofloxacin also helps treat bacterial infections of the urethra, cervix, urinary tract, bladder, bones, skin, ears, nose and eyes.

Ofloxacin fights against both Gram-negative as well as Gram-positive bacteria. It damages double stranded bacterial DNA and hinders DNA relaxation, thus inhibiting the synthesis of bacterial DNA. In this way, Ofloxacin inhibits the process of cell division for bacterial DNA, which helps you to get rid of a bacterial infection.

Ofloxacin is available in the form of tablets or capsules that are taken orally, in the form of eye or ear drops and can also be injected intravenously. It is advisable to take this medication only under the strict guidelines of your doctor. Follow this prescription through until the course is complete, even if the symptoms disappear. You should not skip a dose and avoid taking an extra tablet to make up for it.

It is possible for some people to experience a few common side effects from taking Ofloxacin like headaches, diarrhea, nausea, vomiting, trouble sleeping and dry mouth. These side effects are minor and may not require medical attention, unless they persist for over a week. However, there are certain severe side effects such as hallucinations, tendonitis, mood swings, anxiety, irregular heartbeat, fatigue and a numbing sensation of the feet or hands. Not everyone experiences these side effects, it occurs only in a few cases. If you do experience any of these side effects, seek medical help immediately. If you are allergic to Ofloxacin, you might experience symptoms such as itchiness, swollen tongue, face, throat, hands or feet, trouble breathing and rashes. You should stop taking this medicine as soon as you manifest any of these symptoms and contact your doctor immediately.

Some people are more likely to face harmful side effects, if they also suffer from other conditions like brain disorders, seizures, heart conditions, kidney problems, myasthenia gravis, liver disease, epilepsy, tendonitis, an antibiotic allergy, bone disorders and problems of the joints. It is advisable to inform your doctor of these conditions beforehand, if he/she recommends taking Ofloxacin. It is advisable for pregnant women, women who are breastfeeding and children below 16 years, to avoid taking this antibiotic, since it can lead to harmful consequences.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Internal Medicine Specialist before using this medicine.

Ofloxacin is used in the treatment of Community-Acquired Pneumonia which is a most common type of lung infection caused by Streptococcus pneumoniae, Haemophilus influenzae.
Ofloxacin is used in the treatment of bronchitis which is an inflammation in lungs caused by Streptococcus pneumoniae, Haemophilus influenzae, and some Mycoplasma Pneumonia.

Pyelonephritis

Ofloxacin is used in the treatment of Pyelonephritis which is a type of kidney infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

Cystitis

Ofloxacin is used in the treatment of cystitis which is a bladder infection caused by E.coli, Pseudomonas aeruginosa, Enterococci and Klebsiella pneumoniae.

Prostatitis

Ofloxacin is used in the treatment of Prostatitis (inflammation of the prostate gland that produces semen) caused by Escherichia coli, Pseudomonas and Enterococcus species.
Ofloxacin is used in the treatment of Gonococcal infection which is a sexually transmitted bacterial infection caused by Neisseria gonorrhoeae.

Joint infection

Ofloxacin is used in the treatment of bone and joint infections caused by Enterobacter cloacae, Pseudomonas aeruginosa.

Pneumonia with cystic fibrosis

Ofloxacin is used in the treatment of Pneumonia with Cystic Fibrosis (an inherited disease that causes thick mucus to build up in the lungs and promotes the growth of bacteria like Staphylococcus aureus and Hemophilus influenzae).
Avoid taking Ofloxacin if you have a known allergy to this medicine or any other medicines belonging to the class fluoroquinolones.

Tendinitis or tendon rupture

Avoid taking this medicineif you have a past history of tendinitis or tendon rupture after using Ofloxacin.
Avoid taking this medicine if you have a past or family history of suffering from Myasthenia Gravis (weakness and rapid fatigue of muscles under voluntary control).
In addition to its intended effect, Ofloxacin may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Diarrhea

Major Common

Abdominal pain

Major Rare

White patches in the mouth or on the tongue

Major Rare

Joint pain

Major Rare

Black or tarry stools

Major Rare

Fever with chills

Major Rare

Chest tightness

Major Rare

Ringing or buzzing in the ears

Major Rare

Muscle pain

Major Rare

Numbness of the hands

Major Rare

Swelling of face, lips, eyelids, tongue, hands and feet

Major Rare

Running nose

Minor Less Common

Sneezing

Minor Less Common

How long is the duration of effect?

The effect of this medicine lasts for a duration of 12 to 20 hours.

What is the onset of action?

The peak effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

Are there any pregnancy warnings?

Use of this medicine is not recommended in pregnant women. Use only if clearly needed under the supervision of the doctor.

Is it habit forming?

No habit forming tendency has been reported.

Are there any breast-feeding warnings?

Use of this medicine is not recommended in women who breastfeed due to the adverse effect on development of the infant's joints. Use only if clearly needed under the supervision of the doctor. Avoid breastfeeding for about 3 to 4 hours to decrease the infant's risk exposure. Monitoring of undesired effects like diarrhea, diaper rash is necessary.

Are there any missed dose instructions?

The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

Are there any overdose instructions?

Seek emergency medical treatment or contact the doctor in case of overdose.

India

United States

Japan

Below is the list of medicines, which contains Ofloxacin as ingredient
Laborate Pharmaceutical Ltd
Intas Pharmaceuticals Ltd
Cadila Pharmaceuticals Ltd
Jenburkt Pharmaceuticals Ltd
Allergan India Ltd
Neon Laboratories Ltd
Ranbaxy Laboratories Ltd
Merck Consumer Health Care Ltd
Fresenius Kabi India Pvt Ltd
Delcure Life Sciences
Embiotic Lab
Ranbaxy Laboratories Ltd
Ranbaxy Laboratories Ltd
Hippo Labs Pvt. Ltd
Abbott Healthcare Pvt. Ltd
Alkem Laboratories Ltd
Macleods Pharmaceuticals Pvt.Ltd
Marc Pharma
Abbott Healthcare Pvt. Ltd
Ofloxacin belongs to the class fluoroquinolones. It works as a bactericidal by inhibiting the bacterial DNA gyrase enzyme, which is essential for DNA replication, transcription, repair, and recombination. This leads to expansion and destabilization of the bacterial DNA and causes cell death.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Central nervous system disorders

Major
If you suffer from CNS disorder and you take Ofloxacin, then you may experience tremors, restlessness, anxiety, confusion and hallucinations. Avoid consuming caffeine containing products like coffee, chocolates and energy drinks.

Colitis

Major
Avoid taking Ofloxacin if you experience severe diarrhea, abdominal pain, and blood in stools after taking the medicine. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.

QT Prolongation

Major
Avoid using Ofloxacin if you experience any chest discomfort. Regular cardiac function tests are to be performed if you have any heart disease (arrhythmia) or family history of heart disease.

Interaction with Alcohol

Alcohol

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Lab Test

Lab

Information not available.

Interaction with Food

Dairy products

Moderate
The desired effect of Ofloxacin is not observed if consumed with dairy products. There should be at least 2 hours gap between taking Ofloxacin and dairy products.

Interaction with Medicine

Corticosteroids

Major
You may experience pain, swelling, or inflammation in ankle, shoulder, hand, or thumb if these medicines are used together. This interaction is more likely to occur in elderly population who have undergone a kidney or heart transplantation. Replacement of the medicine should be made under the doctor's supervision.

Escitalopram

Major
You may experience dizziness, lightheadedness, shortness of breath, or heart palpitations if these medicines are used together. This interaction is more likely to happen if you suffer from any heart disease (Arrhythmia) or have a family history of Arrhythmia. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

Quinidine

Major
You may experience dizziness, lightheadedness, and heart palpitations if these medicines are used together. Regular cardiac function tests are to be performed if you have any heart disease (Arrhythmia) or a family history of Arrhythmia. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

Antidiabetic medicines

Moderate
You may experience hypoglycemic effects like dizziness, headache, nervousness, confusion, tremor and weakness if these medicines are used together. Hyperglycemic effects like increased thirst, urination and hunger are less likely to occur. Regular blood glucose checkups are to be performed if you are diabetic or has any kidney disease. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

Aspirin

Moderate
You may experience tremors, involuntary muscle movements, hallucinations, or seizures if these medicines are used together. This interaction is more likely to happen if you have a history of seizures or family history of seizures. Appropriate dose adjustment or replacement of the medicine should be made under the doctor's supervision.

Ethinyl Estradiol

Moderate
The desired effect of contraceptive pills will not be achieved if these medicines are used together. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
What are you using Ofloxacin for?
Other
Pneumonia
Cystitis
Prostatitis
Pyelonephritis
Joint infection
Bronchitis
Gonococcal Infection
Pneumonia with cystic fibrosis
How much was the improvement?
Poor
Average
Excellent
How long did it take before seeing improvement?
More than 2 days
Within 2 hours
Within 6 hours
Within a day
Within 2 days
How frequently did you take this medicine?
Twice a day
Once a day
Not taking on daily level
Thrice a day
Four times A Day
How did you take this medicine?
With Food
With or without food
Empty stomach
What were the side effects of this medicine?
Other
Diarrhea
Muscle pain
Abdominal Pain
running nose
Stomach gas
Joint Pain
Dizziness
Black or tarry stools
Numbness of the hands
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I have been suffering ringworm. I have used many tablet and ointment like terbinafine, fluconazole, ofloxacin and many more. Still I am nt able to treat. Help me for solution.

MBBS, MBA (Healthcare)
General Physician, Delhi
use surfaz sn ointment daily in night for 4 weeks. candid powder daily after bath for one month. it will help you.

Hi, I am suffering from eye stye for last two weeks does using ofloxacin ointment is good for eye stye.

C.S.C, D.C.H, M.B.B.S
General Physician, Alappuzha
Hi, I am suffering from eye stye for last two weeks does using ofloxacin ointment is good for eye stye.
Ofloxacin drops is useful for infection of the stye or eye lid and unless you have infected style there is no need for the drops

I am 49 years female. Can I take ofloxacin 200 mg with rabeprazole for bacterial infection in scaphiod.

MD - Pathology
General Physician, Amritsar
I am 49 years female. Can I take ofloxacin 200 mg with rabeprazole for bacterial infection in scaphiod.
Yes oflixacin will take care of your infection and rabeprazole will correct acidity arising because of medicine but for scaphoid infection I would suggest you must see an orthopaedic surgeon for expert opinion.
1 person found this helpful

I have been suffering from conjunctivitis for about one and half month, still I am not cured. Please help me ,i am using "ofloxacin ophthalmic solution" as prescribed by my doctor. Please help!

Fellowship In Comprehensive Ophthalmology, DOMS
Ophthalmologist, Sangrur
I have been suffering from conjunctivitis for about one and half month, still I am not cured. Please help me ,i am us...
hello it is conjunctivitis Prevention a. maintain eye hygiene b. use two handkerchief (one for each eye) c. keep hands clean Treatment a. antibiotic - soft steroid combination b. lubricating eyedrop c. antibiotic ointment at night kindly consult l...
1 person found this helpful

Popular Health Tips

Avoid The Ban Medicines To Be Safe

BHMS
Homeopath, Singrauli
Avoid The Ban Medicines To Be Safe
Govt bans 344 drugs, including phensedyl, corex Sr. No. Product name (irrational fdc) 1 aceclofenac + paracetamol + rabeprazole 2 nimesulide + diclofenac 3 nimesulide + cetirizine + caffeine 4 nimesulide + tizanidine 5 paracetamol + cetirizine + c...
239 people found this helpful

UTI In Children - Understanding The Ways It Can Be Treated!

MBBS, MS - General Surgery, MCh - Paediatric Surgery
Pediatric Surgeon, Kolkata
UTI In Children - Understanding The Ways It Can Be Treated!
UTI stands for urinary tract infections. In children a urinary tract infection (UTI) is a very common condition caused by bacteria. Bacteria that enter the urethra are flushed out through urination. But, when bacteria aren t excluded out of the ur...
1943 people found this helpful

Leprosy: Treatment and Prevention

MD - Dermatology , Venereology & Leprosy, MBBS
Dermatologist, Gurgaon
Leprosy: Treatment and Prevention
Mentioned throughout history as a curse, leprosy was considered as a punishment of sins by many cultures as it was widespread and common. However, modern science demystified it and de-stigmatized it to the point where the occurrence of leprosy wit...
4216 people found this helpful
Table of Content
About Ofloxacin
When is Ofloxacin prescribed?
What are the contraindications of Ofloxacin ?
What are the side effects of Ofloxacin ?
Key highlights of Ofloxacin
What are the dosage instructions?
Where is the Ofloxacin approved?
Medicines containing Ofloxacin
How does medicine works?
What are the interactions for Ofloxacin ?