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Overview

Tuberculosis - Symptom, Treatment And Causes

Tuberculosis is a disease that dates as back as the Ancient Egyptian civilization of the Pharaohs. For its presence has been found in the preserved spines of the ancient Egyptian mummies. During the 18th and 19th century, an epidemic of this fearsome disease rampaged throughout North America and Europe, before Robert Koch the German microbiologist discovered the cause of tuberculosis in 1882. Following Robert Koch’s discovery, vaccine and effective drug treatment that was developed, led to the belief that this illness has been almost defeated. At a point of time, even the United Nations, suggested that TB (Tuberculosis) would get eliminated by 2025.

Nevertheless, the counts of the patients suffering from this disease started to rise in the US and worldwide in the mid-80s. In 1993 the WHO (World Health Organization) declared Tuberculosis as a global emergency. Although with proper diet and medications this disease is curable, but without proper treatment experts say that two third of the people suffering from TB will die.

There are two types of Tuberculosis:

  • Latent TB
  • Active TB

In the latent TB cases, the TB bacteria remain in a dormant mode in the body. It doesn’t cause any symptoms of the disease and so is not contagious. However, the latent TB bacteria can become active any point of time. About one third of the world population is believed to have latent TB. Although there is only 10% chance that latent TB will get active, but people who have compromised immune system, have higher risks of triggering this latent disease. In active TB, the disease causing bacteria shows symptoms of TB and this illness is contagious. TB can affect all age groups in all parts of the global demography.

TB is caused by Mycobacterium tuberculosis bacterium. This disease spreads through the air, when someone suffering from this disease sneezes, coughs, laughs, talks or spit. Although TB is contagious, but it is not easy to catch. However, the chances of getting infected with this disease is more from someone you work or live, rather than from a stranger. With people suffering from active TB, it take not more than two weeks to be non-contagious, if they are provided proper medications.

In most of the cases the common diagnostic test for detecting this disease is a skin test whereby a small injection of PPD tuberculin (which is an extract of the TB bacterium) is given below the inside forearm of the patient. The injection site is then checked after 2-3 days. If the site of the injection shows signs of red bump, gets swollen and hard, then it’s likely that the patient is suffering from TB. Apart from that, other tests which are also used for diagnosis of this disease are blood tests, x-ray of the patient’s chest, which are done along with the above mentioned skin test.

Treatable by medical professional Require medical diagnosis Lab test always required Short-term: resolves within days to weeks Spread through the air or contaminated surfaces
Symptoms
Feeling chilly and having fever. Coughing, which sometimes spurts out mucous and blood. Loss of appetite leading to weight loss. Night sweats and loss of energy during the morning hours of the day.

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Know About Tuberculosis

Dr. Srikanth Md 92% (910 ratings)
MD(Am)
General Physician, Secunderabad
Definition Tb is a disease which in humans is usually caused by bacteria called mycobacterium tuberculosis (m. Tuberculosis). Tb is an abbreviation of the word tuberculosis and is how people often refer to the disease. Bovine tb is a disease caused by similar bacteria called mycobacterium bovis (m. Bovis). Bovine tb mainly affects cattle but can also affect humans. Just a few years ago it was believed that tb was an old disease, and that it was no longer a problem in humans. But now because of such issues as drug resistance and hiv, it has become a major problem again. History On march 24, 1882, Dr. Robert koch announced the discovery of mycobacterium tuberculosis, the bacteria that cause tuberculosis (tb). During this time, tb killed one out of every seven people living in the united states and europe. Dr. Koch s discovery was the most important step taken toward the control and elimination of this deadly disease. In 1982, a century after Dr. Koch s announcement, the first world tb day was sponsored by the world health organization (who) and the international union against tuberculosis and lung disease (iuatld). The event was intended to educate the public about the devastating health and economic consequences of tb, its effect on developing countries, and its continued tragic impact on global health. Today, world tb day is commemorated across the globe with activities as diverse as the locations in which they are held. But more can be done to raise awareness about the effects of tb. Among infectious diseases, tb is now the leading killer of adults in the world, with 1.8 million tb-related deaths in 2015. In the united states, the overall number of tb cases increased over the previous year in 2015 after having declined yearly during 1993 2014. Until tb is eliminated, world tb day won t be a celebration. But it is a valuable opportunity to educate the public about the devastation tb can spread and how it can be stopped. Epidemiology Globally, more than 1 in 3 individuals is infected with tb. According to the who, there were 8.8 million incident cases of tb worldwide in 2010, with 1.1 million deaths from tb among hiv-negative persons and an additional 0.35 million deaths from hiv-associated tb. In 2009, almost 10 million children were orphaned as a result of parental deaths caused by tb. Overall, the who noted the following: The absolute number of tb cases has been falling since 2006 (rather than rising slowly, as indicated in previous global reports) Tb incidence rates have been falling since 2002 (2 years earlier than previously suggested) Estimates of the number of deaths from tb each year have been revised downwards The 5 countries with the highest number of incident cases in 2010 were india, china, south africa, indonesia, and pakistan. India alone accounted for an estimated 26% of all tb cases worldwide, and china and india together accounted for 38%. Types 1. Active tb Active tb is an illness in which the tb bacteria are rapidly multiplying and invading different organs of the body. The typical symptoms of active tb variably include cough, phlegm, chest pain, weakness, weight loss, fever, chills and sweating at night. A person with active pulmonary tb disease may spread tb to others by airborne transmission of infectious particles coughed into the air. If you are diagnosed with an active tb disease, be prepared to give a careful, detailed history of every person with whom you have had contact. Since the active form may be contagious, these people will need to be tested, as well. Multi-drug treatment is employed to treat active tb disease. Depending on state or local public health regulations, you may be asked to take your antibiotics under the supervision of your physician or other healthcare professional. This program is called directly observed therapy and is designed to prevent abandonment or erratic treatment, which may result in failure with continued risk of transmission or acquired resistance of the bacteria to the medications, including the infamous multi-drug resistant tb (mdr-tb). 2. Miliary tb Miliary tb is a rare form of active disease that occurs when tb bacteria find their way into the bloodstream. In this form, the bacteria quickly spread all over the body in tiny nodules and affect multiple organs at once. This form of tb can be rapidly fatal. Types of tb 1. Cavitary tb Cavitary tb involves the upper lobes of the lung. The bacteria cause progressive lung destruction by forming cavities, or enlarged air spaces. This type of tb occurs in reactivation disease. The upper lobes of the lung are affected because they are highly oxygenated (an environment in which m. Tuberculosis thrives). Cavitary tb can, rarely, occur soon after primary infection. Symptoms include productive cough, night sweats, fever, weight loss, and weakness. There may be hemoptysis (coughing up blood). Patients with cavitary tb are highly contagious. Occasionally, disease spreads into the pleural space and causes tb empyema (pus in the pleural fluid). 2. Latent tb infection Latent tb occurs when a person has the tb bacteria within their body, but the bacteria are present in very small numbers. They are kept under control by the body s immune system and do not cause any symptoms. People with latent tb do not feel sick and are not infectious. They cannot pass the bacteria on to other people. In addition they will usually have a normal chest x-ray and a negative sputum test. It is often only known that someone has latent tb because they have had a test, such as the tb skin test. Risk factors You are at risk of tb infection if you are around people with active tb disease who are coughing, which releases bacteria into the air. The risk of infection increases for intravenous drug users, healthcare workers, and people who live or work in a homeless shelter, migrant farm camp, prison or jail, or nursing home. Most people who are infected with the bacteria that cause tb do not develop active disease. The following factors increase the risk that latent disease will develop into active disease: Infection with hiv, the virus that causes aids and weakens the immune system Diabetes mellitus Low body weight Head or neck cancer, leukemia, or hodgkin s disease Some medical treatments, including corticosteroids or certain medications used for autoimmune or vasculitic diseases such as rheumatoid arthritis or lupus, which suppress the immune system. Silicosis, a respiratory condition caused by inhaling silica dust. Causes The mycobacterium tuberculosis bacterium causes tb. It is spread through the air when a person with tb (whose lungs are affected) coughs, sneezes, spits, laughs, or talks. Causes of tuberculosis Tb is contagious, but it is not easy to catch. The chances of catching tb from someone you live or work with are much higher than from a stranger. Most people with active tb who have received appropriate treatment for at least 2 weeks are no longer contagious. Since antibiotics began to be used to fight tb, some strains have become resistant to drugs. Multidrug-resistant tb (mdr-tb) arises when an antibiotic fails to kill all of the bacteria, with the surviving bacteria developing resistance to that antibiotic and often others at the same time. Mdr-tb is treatable and curable only with the use of very specific anti-tb drugs, which are often limited or not readily available. In 2012, around 450, 000 people developed mdr-tb. Symptoms Although tuberculosis (tb) is most frequently associated with symptoms involving the lungs because the disease most often affects the lungs it can affect any organ of the body. The disease can cause a variety of symptoms. If you have symptoms, your doctor will want to know when they began. People with latent tb infection (an infection without active disease) have no symptoms. The usual symptoms of tb include: Fever Chills Night sweats Cough Loss of appetite Weight loss Blood in the sputum (phlegm) Loss of energy The symptoms may be mild and may not seem particularly worrisome to the patient. In other people, the symptoms become chronic and severe. Other symptoms of active tb disease depend on where in the body the bacteria are growing. If active tb disease is in the lungs (pulmonary tb), the symptoms may include a bad cough, pain in the chest, and coughing up blood. If active tb is outside the lungs (for example, the kidney, spine, brain, or lymph nodes), it is called extrapulmonary tb and has other symptoms, depending on which organs are affected. For example, tuberculosis in the spine may cause back pain or stiffness. Diagnosis and test During the physical exam, your doctor will check your lymph nodes for swelling and use a stethoscope to listen carefully to the sounds your lungs make while you breathe. The most commonly used diagnostic tool for tuberculosis is a simple skin test, though blood tests are becoming more commonplace. A small amount of a substance called ppd tuberculin is injected just below the skin of your inside forearm. You should feel only a slight needle prick. Within 48 to 72 hours, a health care professional will check your arm for swelling at the injection site. A hard, raised red bump means you re likely to have tb infection. The size of the bump determines whether the test results are significant. If your gp suspects you may have tb, they will send you for testing. If you do have tb, it s best to know as soon as possible. Delaying treatment makes it more likely you may develop long-term health problems and could put people close to you at risk. Types of tb test There are a range of tests to show if you have tb, such as a sputum test, a culture test and x-rays. Chest x-ray A chest x-ray can show damage in your lungs, but you might need further tests to prove you have tb, such as sputum and culture tests or scans. Testing sputum A lab will use a microscope to look at any sputum (phlegm) that you cough up. If there are tb germs in your sputum, you have tuberculosis of the lungs or throat (pulmonary tb). This test also helps doctors to understand how infectious you may be. Biopsy If it is thought that you have tb, but not in your lungs or throat, the doctor may take a biopsy to test for tb. This is a small sample of tissue or fluid taken from the area where the tb is thought to be. Culture test This test uses your sputum or tissue sample to grow any tb bacteria that may be there. It tells doctors how infectious you are and also whether your tb is resistant to any antibiotics. This helps ensure they put you on a combination of drugs that will cure you. As tb culture grows slowly, it may take up to eight weeks to get some of the results. Treatment and medications Treatment for active tb If you have this form of the disease, you ll need to take a number of antibiotics for 6 to 9 months. These four medications are most commonly used to treat it: Ethambutol Isoniazid Pyrazinamide Rifampin Your doctor may order a test that shows which antibiotics will kill the tb strain. Based on the results, you ll take three or four medications for 2 months. Afterward, you ll take two medications for 4 to 7 months. You ll probably start to feel better after a few weeks of treatment. But only a doctor can tell you if you re still contagious. If you re not, you may be able to go back to your daily routine. Treatment of latent tb The treatment of latent tb is considered by many people to be an important part of tb prevention. It is not recommended that everyone with latent tb infection (ltbi) should have tb treatment. Rather it is recommended that certain target groups should receive treatment. The main target groups considered by the world health organisation (who) to be most at risk from progressing from latent to active tb include people in low tb burden countries: Who have had recent contact with an infectious patient; With silicosis (there is more about tb & mining); Infected with both tb and hiv; Who have been or who are in prison; Who are immigrants to a low burden country from a high burden country; Who are homeless; Who are an illicit drug user; Who have certain clinical conditions, or conditions which compromise their immune system, such as people with diabetes, and people with chronic renal failure. In high tb burden countries the populations that are most strongly recommended for the treatment of latent tb infection are people living with hiv, and children under five who are household contacts of pulmonary tb cases. Treatment for miliary tb Antibiotics Corticosteroids Sometimes surgery Generally, treatment of miliary tuberculosis is similar to thetreatment of pulmonary tuberculosis. Antibiotics are given usually given for 6 to 9 months, unless the meninges are affected. Then antibiotics are given for 9 to 12 months. Corticosteroids may help if the pericardium or meninges are affected. Tuberculosis bacteria can easily develop resistance to antibiotics, particularly when people do not take the drugs regularly or for as long as they are supposed to. Surgery is needed for some complications of military tuberculosis. Prevention If you test positive for latent tb infection, your doctor may advise you to take medications to reduce your risk of developing active tuberculosis. The only type of tuberculosis that is contagious is the active variety, when it affects the lungs. So if you can prevent your latent tuberculosis from becoming active, you won t transmit tuberculosis to anyone else. Protect your family and friends If you have active tb, keep your germs to yourself. It generally takes a few weeks of treatment with tb medications before you re not contagious anymore. Follow these tips to help keep your friends and family from getting sick: Stay home. Don t go to work or school or sleep in a room with other people during the first few weeks of treatment for active tuberculosis. Ventilate the room. Tuberculosis germs spread more easily in small closed spaces where air doesn t move. If it s not too cold outdoors, open the windows and use a fan to blow indoor air outside. Cover your mouth. Use a tissue to cover your mouth anytime you laugh, sneeze or cough. Put the dirty tissue in a bag, seal it and throw it away. Wear a mask. Wearing a surgical mask when you re around other people during the first three weeks of treatment may help lessen the risk of transmission. Finish your entire course of medication This is the most important step you can take to protect yourself and others from tuberculosis. When you stop treatment early or skip doses, tb bacteria have a chance to develop mutations that allow them to survive the most potent tb drugs. The resulting drug-resistant strains are much more deadly and difficult to treat. Vaccinations In countries where tuberculosis is more common, infants often are vaccinated with bacillus calmette-guerin (bcg) vaccine because it can prevent severe tuberculosis in children. The bcg vaccine isn t recommended for general use in the united states because it isn t very effective in adults. Dozens of new tb vaccines are in various stages of development and testing.

Tuberculosis Of Spine - An Insight!

Dr. Gururaj Sangondimath 86% (23 ratings)
Fellowship in spinal tumor surgery, Fellowship in Cervical spine surgery, FNB Spine Surgery, Fellowship in spinal deformity, fellowship in MInimalli invasive(Keyhole) surgery, CPC paliative care, MS-Orthopaedics, MBBS
Orthopedist, Delhi
Tuberculosis Of Spine - An Insight!
A few decades back, spinal tuberculosis was a dreaded disease. It is not so, anymore. With advancements in the medicinal field, when diagnosed in the early stages, a complete cure is possible. Tuberculosis of the spine is one of the most common spine ailments in our country. Though there was no treatment when the disease was first reported, recent improvements in medical treatment and surgical procedures have made the condition treatable. In many cases, the disease is cured completely. Molecular genetic techniques, stronger antibiotics and other medicinal discoveries and inventions have been able to combat the condition, which is resistant to a huge number of drugs. There are many surgical procedures as well, which has changed the way spine TB is looked at. These include extrapleural dorsal spine anterior stabilization, endoscopic thoracoscopic surgeries, single stage anterior and posterior stabilization among others. How is it caused? Tuberculosis affects people living in overcrowded, dirty and poorly nourished environments. The aerobic organism that is responsible for this physical condition is Mycobacterium tuberculosis, which grows rapidly in unfavorable conditions. It grows only intermittently or remains dormant for a long period to then re-grow whenever the immunity system of the host weakens. What are the different types of TB spine? Spinal tuberculosis takes two forms. In the first case, the symptoms are mild. The infection starts in the anterior part of the disc and slowly spreads to the nearby surface of the body. The neural arches are very rarely involved here. This results in a vertebral collapse. The spine bends forward to produce kyphus. In the second type, several vertebrae are involved, but the disc space might not become narrow. What are the symptoms of TB spine? The first symptom is an excessive pain in the back, which manifests as kyphosis increases. Kyphosis is the condition wherein there is an increase in the normal convex curve of the spine. Later, pus forms at the infected vertebrae and this comes down to the tissue planes and forms a cold abscess in uncommon places. This happens in the groin region, and the person may become paraplegic. In a child, spinal tuberculosis will cause them to constantly complain about back pains. They will not feel well for a long period and will gradually lose weight. They may not want to sit for a long time and resent any physical activity. The child will be vulnerable in the low thoracic or upper lumbar spine and can show any of the above-mentioned signs that are seen in adults. The most common symptoms of spinal tuberculosis are kyphus, reduction in the movement of the lumbar spine, cold abscesses in the paraspinal area, groin and loin, and sinuses. The doctor always tests the reflexes in the patient s legs, sensation, power, and tone before diagnosing this condition. Though a rare disease, tuberculosis in the spine can occur in people from both developed and undeveloped areas. Proper diagnosis and treatment of tuberculosis with or without surgery at the right time is the key to cure the disease.
1 person found this helpful

Ayurvedic Tips To Survive Air Pollution

Dr. Piyush Juneja 86% (448 ratings)
Bachelor of Ayurveda, Medicine and Surgery (BAMS), PGCRCDM, PDCR, MBA
Ayurveda, Ghaziabad
Ayurvedic Tips To Survive Air Pollution
There are herbal preparations, which adsorb pollutants and may also help detoxify the effects." One must wash the skin, hair with neem leaves boiled in the water. It will clear the pollutants stuck to skin and mucosal membrane. If possible, also try to eat three to four leaves at least twice a week. It helps to purify blood and lymphatic tissue. Tulsi (basil) should be planted at every house to absorb the pollution. In addition, one should drink 10-15 ml of tulsi juice as it helps clear pollutants from the respiratory tract Turmeric powder half teaspoon with 1 tablespoon of ghee or honey, should be taken empty stomach in the morning One can put 2 drops of cow ghee in each nostril every day in the morning and at bed time to stay clear from pollutants., "It is important to have two to three teaspoon of homemade ghee daily. It is very much useful to chelate the toxic effects of metals like lead and mercury and does not allow them to accumulate in bones, kidneys and liver. Pippali is one of the super herbs for purifying lungs that enable easy breathing. It's very effective against lung infections due to its rejuvenative properties. A simple way to consume this is teaspoon Ginger, teaspoon turmeric and 1/8 teaspoon Pippali powder mixed in 1 tbsp honey and washed down with warm water. This should however be taken for maximum of seven days and not used in infants. Pollution causes imbalance in tridosha and Triphala helps restore the same, thus, bolstering immunity. One tablespoon of Triphala with 1 teaspoon of honey at night is the recommended dosage Drink pomegranate juice as it is known to purify blood and is also a brilliant cardio protective fruit. Dr Piyush Juneja, suggests a daily full-body warm oil massage aka Abhyangam, therefore, acts as a powerful recharger and rejuvenator of mind and body. Luke Coutinho, holistic healing expert recommends taking steam with 5-10 drops of eucalyptus oil or a drop of peppermint oil. This should be done for five minutes twice a day. Dhoop (smoke created in earthen bowl) of Guggulu and Aguru, which are Ayurvedic herbs can be used to prevent dampness in the house, which is a leading cause of allergic cold and breathlessness Eat home cooked, warm food instead of eating out at restaurants. Incorporate herbs like turmeric, cayenne pepper, carom seeds, ginger etc in food. Add some pepper, and basil leaves to your regular cup of chai.

HIV - Understanding Its Relation With Tuberculosis!

Dr. R.Pavan Kumar 87% (31 ratings)
MBBS, PGDHS,PGDHIVM
General Physician, Hyderabad
HIV - Understanding Its Relation With Tuberculosis!
HIV and tuberculosis (TB) are two life-threatening and common diseases in the world. The two diseases are very closely connected so much so that their occurrence is normally labeled as a co-epidemic. In most cases tuberculosis is found to be the most transmissible contagion in HIV-Immunocompromised victims, proving to be the cause of their death. What is HIV? Human Immunodeficiency Virus, more commonly known by its abbreviation HIV, is a virus that attacks the immune system, which is the body's natural defense against illnesses. The virus terminates a kind of white blood cells (WBCs) in the immune system known as the T-helper cell also known as CD4 cells. This virus then proceeds to duplicate itself within these cells. As HIV reduces the T-helper cells, by duplicating at an increasing rate, it slowly breaks down the patient s immune system. This leaves the individual susceptible to other deadly diseases such as tuberculosis. HIV infection is a permanent disease with three phases of progression. HIV medications can reduce or stop the evolution of the disease from one phase to another. The treatment can also decrease the chances of spreading HIV to other people. What is tuberculosis (TB) Tuberculosis is a transmittable disease triggered by the presence of bacterium known as Mycobacterium tuberculosis. It is still considered a deadly disease in most developing countries where treatment is scarce. Generally, TB affects the lungs but it can also affect other parts of the body. Symptoms include coughing with blood, fever, night sweats and loss of weight. The relation between TB and HIV In second world countries, most patients infected with HIV suffer from TB as the initial indicator of AIDS. Tuberculosis can occur at any phase of the HIV infection. The danger and severity of tuberculosis rises rapidly after infection with HIV. Even though tuberculosis can be a fairly primary indicator of HIV infection, it is imperative to observe that the risk of tuberculosis increases as the CD4 cell count reduces along with the progression of the HIV infection. Treatment Positive treatment for TB usually entails 6 months of rigorous therapy. HIV patients with TB usually respond well to this therapy, if the regimen comprises INH and a rifamycin for the period of TB therapy and cure. TB generally reappears when the immune system is unable to respond to stop the development of mycobacteria. The cytokine IFN- plays a key role in the response of the immune system all through the contagion. HIV and TB infections area two-directional communication of the two pathogens. TB is one of the main causes of disease and fatality among patients with HIV in Africa and other severely affected regions. With almost a 50% kill rate around the world, raising awareness about this disease and consulting doctors when signs or symptoms appear is vital in reducing the extent of this epidemic. Rifampicin- HIV treatment are complicated by the fact that one of the key drugs used in TB treatment, rifampicin, reduces blood levels of nevirapine (Viramune) by 30 to 55% and also reduces levels of most protease inhibitors.
3078 people found this helpful

Tuberculosis During Pregnancy

Dr. Pallavi Vasal 85% (99 ratings)
MBBS, D.G.O, Fellowship in Minimal Access Surgery, Membership of Royal College of Obstetrics & Gynaecology
Gynaecologist, Gurgaon
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Tuberculosis: Treatment and Management
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Popular Questions & Answers

I have tb I am on my medication, I have mediastinal lymph node swollen and many others. I am scared will that mediastinal lymph node make me breathless is compresses lungs or can I get heart problem if compresses heart.

Dr. Amit Kumar Poddar 91% (72 ratings)
MBBS, MD TUBERCULOSIS AND CHEST DISEASES, Diploma in Tuberculosis & Chest Diseases, Diploma in Tropical Medicine and Hygiene
Pulmonologist, Kolkata
Don't get frightened about the possibility of compression on lungs and heart by enlarged lymph nodes. Your responsibility is to complete the anti tubercular drugs under the guidance of tuberculosis specialist.In a small percentage of patients to obviate this compression oral steroids under the guidance of Tuberculosis specialist for 4 to 6 to eight weeks may be needed. Wish you speedy recovery.
1 person found this helpful

Tb-what is a role kya hai. TB ke upchar nhi pta. TB ki dba to batao. Please help.

Dr. Mool Chand Gupta 89% (33278 ratings)
MD PULMONARY, DTCD
Pulmonologist, Faridabad
four medicine in intensive phase of 2 months and 3 medicine in continuation phase of 4 months in a freash TB case
1 person found this helpful

How long will it take for the chest X Ray to be clear. As the fluid is mild and not capable. How you know it's Tb.

Dr. Amit Kumar Poddar 91% (72 ratings)
MBBS, MD TUBERCULOSIS AND CHEST DISEASES, Diploma in Tuberculosis & Chest Diseases, Diploma in Tropical Medicine and Hygiene
Pulmonologist, Kolkata
It is totally unpredictable how long it may take for Chest xray to clear, varies with individual patient's response to anti tubercular drugs. Pleural fluid ADA 44 IU/L is a strong pointer for diagnosis of Tubercular Pleural Effusion inspite of the fluifd being mild and not tapable. Wish you good health.

I am on xdr tb treatment with Bedaquiline medicine since last 3 month I have done ECG today my QT interval is 457 is this normal.

Dr. Abaranam I 89% (34 ratings)
Mbbs, Diploma in Tuberculosis and Chest Diseases (DTCD)
Pulmonologist, Chennai
Hi, you are in borderline increased long qt intervel. Usually when it is more than 500 it is highly significant. So repeat this ECG. Still is high we need to rethink to stop Bedaquiline. Get well.
1 person found this helpful

HI, My father, aged 68, one month back suffered from gastroenteritis. On the 4th day, he started to complain of low back pain with fever and chills. Almost a month now after showing him to different doctors we hospitalise him and we were informed that his is having sepsis causing kidney dysfunction and pulmonary edema. After 10 days in hospital, he is very weak with haemoglobin at 6.9 and platelet count at 150. He still feels the low back pain - it is felt upon movement, or posture change but not on lying down in one position. He generally complains the pain as being on the back sides under the rib section. His creatinine has come down from 1.4 to 1.31 but doctors say that it could be due to TB though PET scan and biopsy spine is negative. Myeloma is negative as well. Can someone throw some light on what it could be - is it a muscle strain, nerve root pain, kidney infection related pain, IBS infection? Point is he seen Nephrologist, Spine surgeon, Cardiologist, Internal medicine, Neurologist and Pulmunologist but they have mostly cleared him expect for some Kidney infection, and possible Spine TB suspicion. Please note the back pain is mostly being felt around the sides of the low back and not along the spine, it does not even travel along the legs. Also he never had a back pain previously and has always been very active. Please advice.

Dr. Rushali Angchekar 95% (50962 ratings)
BHMS
Homeopath, Sindhudurg
Hi relax .hb is also low. Without detailed case history difficult to find out cause. Fever with chill is indication of sepsis in body. Whatever maybe cause give following medicines. Pyrogen 200 4pills one dose only followed by bry 200 4pills 3 times daily for 3 days calsivita syrup 1spoonful 3 times daily ferrum phos 30x 4pills 3 times nat sulph 6x 4pills 3 times daily for 8 days and revert back for further treatment.
1 person found this helpful

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