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Overview

In Vitro Fertilization: Cost, Procedure, Recovery, Risk & Complication

In-Vitro Fertilization (IVF) consists of a series of procedures that are used for the treatment of genetic or fertility problems, while assisting the conception of a child. One of the most effective forms of assisted reproductive technology, IVF procedures can be conducted using a woman’s own eggs and her partner’s sperm. It can also be done by taking the eggs, sperm or embryos from a known or unknown donor. There are some cases where a gestational carrier (a woman with an embryo implanted in the uterus) can be used.

During IVF, mature eggs are retrieved from a woman’s ovaries and fertilized with the sperms in the lab. Once it has been fertilised, the egg or eggs are implanted back in the uterus. A cycle of IVF can take about 2 weeks.

Indication

One may have to undergo an IVF treatment in the following conditions:

  • If a woman’s fallopian tubes are blocked or damaged
  • If ovulation is infrequent/absent, or there are few eggs available for fertilization
  • Loss of normal functions of the ovary before reaching the age of 40
  • A previous treatment of tubal ligation, where the fallopian pipes have been cut/blocked permanently. In this case, one can opt for IVF instead of tubal ligation reversal.
  • Poor mobility, abnormality in sperm size/shape, or below average concentration of sperm of the male partner
  • If you have the conditions of endometriosis (uterine tissue will implant and grow outside the uterus) or uterine fibroids
  • Unexplained fertility or a genetic disorder

Pre Procedure

Before beginning the process of IVF, both the partners may have to go through certain pre-procedure screenings such as:

  • Ovarian reserve testing, for determining the quality and the quantity of the eggs. The concentration of estrogen, follicle stimulating hormone as well as the antimullerian hormone in your blood is checked by your doctor in the initial days of the menstrual cycle. These test results may help in predicting the response of your ovaries to fertility medications.
  • Analysis of the semen of the male partner
  • Screening for any infectious disease like HIV
  • A mock transfer of the embryo for determining the depth of the uterine cavity and the technique that may work best for you
  • An examination of the uterine cavity that may involve sonohysterography (fluid is injected in the uterus through the cervix and an ultrasound creates images of the uterine cavity) or hysteroscopy
  • Some serious question like the numbers of embryos that will be transferred, what needs to be done with the extra embryos, how to handle a multiple pregnancy, and the complications that may occur with donor eggs and sperms or a gestational carrier have to be discussed.

During Procedure

IVF treatment involves the following steps:

  • Ovulation induction, where synthetic hormones stimulate the ovaries for producing multiple eggs. You have to be under several medications for a week or two before the eggs are ready for retrieval. Vaginal ultrasound or blood tests are examined by the doctor to determine it.
  • Egg retrieval, through a transvaginal ultrasound. In this process, an ultrasound probe is inserted in the vagina for the identification of follicles. A thin needle is guided through the ultrasound guide to reach the vagina for collecting the eggs. The laparoscopy method can also be used for the same.
  • Sperm retrieval through masturbation or testicular aspiration in case the partner’s sperm is being used
  • The next step is fertilization either by insemination (sperm and eggs are incubated overnight) or Intracytoplasmic sperm injection (ICSI), where a single sperm is injected directly in a mature egg.
  • Embryo transfer is next step performed at the doctor’s clinic. It takes place two to six days after the retrieval of the eggs.

Post Procedure

Once the embryo has been transferred, you can go back to your regular schedule. However, your ovaries may be enlarged for a few days, so it is advisable to avoid any vigorous activity that may cause discomfort.

The side effects of post treatment may involve:

  • Passing of a small amount of clear/bloody fluid after the procedure, which is caused because the cervix is swabbed before the transfer of the embryo
  • Mild bloating and cramping
  • Constipation
  • Breast tenderness because of the high levels of estrogen

In case you have a moderate or severe pain after the transferring of the embryo, consult your doctor who will evaluate your condition. Any indication of a complication like an infection pr ovarian torsion can be examined and treated.

Risk & Complication

An IVF procedure may bring along with it certain risks and complications like:

  • Multiple births if more than one embryo has been implanted in the uterus. Multiple foetuses can often lead to premature delivery or a low birth weight of the newborn.
  • The frequent injection of fertility drugs to induce ovulation may lead to ovarian hyperstimulation syndrome, a condition where the ovaries become painful and swollen.
  • Using an aspirating needle for collecting eggs may lead to bleeding, damage or infection in the bowel, bladder or a blood vessel.
  • In some cases, there may be chances of an ectopic pregnancy. This is a condition where the fertilised egg will implant outside your uterus, generally in the fallopian tube. The egg would not be able to survive outside the uterus and the pregnancy will not be possible to be continued.
  • Miscarriage or birth defects
  • There may be a possible connection between some medications used in IVF and a specific type of ovarian tumor, though there have not been enough cases to support it.
  • The procedure of IVF can be physically, emotionally as well as financially draining, leading to stress.

More Info

Make sure that you continue having the medications after the embryo transfer has been successfully completed. It is better to avoid travelling during this period. It is generally after 2 weeks after the embryo transfer that you have to go for a pregnancy test. It is important not to be stressed during this phase, but be optimistic and occupied. Also, the pregnancy test must be conducted by a doctor at the clinic and not by yourself at home.

The cost of an IVF treatment may vary from Rs. 10,000 – Rs. 70,000, depending on your condition.

Popular Health Tips

Increase Your Changes Of Fertility With IMSI!

Dr. K.D Nayar 90% (516 ratings)
MD - Obstetrtics & Gynaecology, DGO, Dip.Obst.(Ireland), FICOG
IVF Specialist, Delhi
Increase Your Changes Of Fertility With IMSI!
Of a million sperms released in one ejaculation, a single sperm manages to fertilize the egg, which grows into an embryo and then a baby. Due to various reasons, when this does not happen, it is termed as infertility and is currently on the rise. With IVF, couples sometimes go through multiple sessions to ensure fertilization. ICSI or intracytoplasmic sperm injection improved this chance of fertilization. It is where a single sperm is used to fertilize an egg in an artificially controlled environment and then injected into the uterus where it grows further. The next step in this technique is IMSI, where the chances of successful pregnancy are further enhanced and also promises improved quality of the embryo. IMSI, as it stands for, has morphologically selected which means under a highly powerful microscope, the best sperms are selected and then used to fertilize the egg. Morphology stands for shape, and the shape of the sperm is a direct indicator of the sperm quality. This not just ensures good success rate but also ensures the sperm which is used produces a high-quality embryo. Features High success rate of fertility Reliable and efficient method of ART (assisted reproductive technology) More expensive than traditional IVF methods or ICSI Requires complex equipment, training, and set-up Indications: Useful in couples who have failed IVF previously Male infertility with unidentifiable cause Poor sperm quality What to expect? Both partners are prepared both physically and mentally prior to IMSI. Before the procedure - men: A screening is first done to decide if the sperms can be used directly In case of hereditary diseases, a donor is preferred The first technical step involves sperm collection, either directly or through a donor Sperms are collected either through masturbation or through a small incision in the testicles Sperms used could be fresh or frozen; fresh ones may be stored for later use also Before the procedure women: The woman is put on some ovulation therapy to ensure the release of multiple eggs, so a good one is picked. These high doses of hormones ensure multiple eggs are released. Egg release is monitored through blood and urine tests They are collected within after 36 hours of release During the IMSI procedure: A healthy egg is chosen and placed in a glass container containing hyaluronidase Sperms are placed in a medium which will slow their movement, which enables picking a good sperm for fertilization The dual advantage of this is that in addition to a high success rate of fertilization, the quality of the embryo is also assured
394 people found this helpful

IVF - Facts That Are Actually Myths!

Dr. Apoorva Pallam Reddy 90% (206 ratings)
MBBS, MS - Obstetrics and Gynaecology, DNB (Obstetrics and Gynecology)
Gynaecologist, Bangalore
IVF - Facts That Are Actually Myths!
In-vitro fertilisation (IVF) is one of the popular Assisted Reproductive Technologies (ART) for treating infertility and helping couples to conceive. But lack of understanding about the IVF treatment has given rise to a number of myths such as: Myth 1: IVF never fails but is always successful The success of the procedure depends on a number of factors such as quality and quantity of embryos and age. It is said that chances of conception decreases with age, with women above 40 reporting reduced fertility potential as well as success rate. On the other hand, women below the age of 35 have about 41% chance of getting pregnant. Myth 2: IVF increases your fertility levels Instead of making you more fertile, IVF stops your natural fertility cycle. This is usually done through hormones that are taken at the beginning of the process. The aim of such an action is to essentially put an end to your natural fertility process and create in its place an artificial cycle. Myth 3: It causes you to have triplets or twins No, it's not necessary for multiple births to take place if you opt for IVF. You can reduce the prospect of having twins or triplets by cutting down on the number of embryos that get inserted into the uterus. Myth 4: IVF hormone injections make you prone to uncontrollable emotions. In actuality, IVF hormone injections don't cause you to suffer from out of control emotions but make you happier. This is because they come packed with the female hormone oestrogen, which produce endorphins (brain chemicals) that give you a sense of wellbeing. The wave of emotions that you end up experiencing is a result of the stress and anxiety surrounding the success of a cycle.
5357 people found this helpful

PCOD - How it Affects Your Body?

Dr. Shilpa Bansal Agrawal 93% (369 ratings)
MBBS, MD - Obstetrtics & Gynaecology, DNB, Fellowship in Infertility
Gynaecologist, Mumbai
PCOD - How it Affects Your Body?
PCOD or polycystic Ovary Disorder is one of the most common disorders of hormones among women in the age of reproduction. It is yet not discovered why some women become susceptible to this disease and it is believed to be a genetic disorder. The word polycystic refers to multiple cysts and a woman suffering from PCOD has multiple cysts in her ovary. This is due to the imbalance of hormones, which don t allow the ovary to release eggs every month and these numerous unreleased eggs present in the ovary cause it to become polycystic. What are the symptoms of PCOD? The regular release of eggs from the ovaries directs a woman s fertility and allows her to have a normal menstrual cycle. Therefore, women with PCOD face difficulty in conceiving along with irregular, low and absent periods. Some of the most common symptoms of PCOD include infertility and even miscarriage, elevated insulin levels, high blood pressure, diabetes, acne, unhealthy weight gain and obesity. It also leads to loss of hair from the scalp and excessive growth of hair on the body. This is due to over production of male hormones that lead to male pattern of growth of hair, such as on chest, cheek, chin and inner thighs. The hormonal imbalance leads to weight gain and obesity makes the hormonal imbalance even worse, turning it into a vicious cycle. How is PCOD diagnosed and treated? Your gynaecologist would be able to determine whether you have PCOD by checking your symptoms. Then she would recommend you to do a few blood tests along with a pelvic ultrasound scan to confirm whether you have PCOD. Though this disease is not reversible, its symptoms may be reduced or minimised. Most women can lead a trouble-free and healthy life if they take proper precautions at the right time. It has been pointed in several studies that reduction in weight can help in the improvement of most PCOD symptoms because fat contributes to the production of certain hormones. Your doctor will prepare a treatment plan depending on the aspect from which you are suffering. For instance, if you are suffering from irregular periods, your doctor may prescribe you some contraceptives which can help in restoring normal menstrual cycle. But this treatment is definitely unsuitable for those who are trying to conceive. The infrequent and irregular ovulation can make it difficult to conceive and it can be artificially induced with the aid of medications. So, you must consult a gynaecologist to help your situation.
4586 people found this helpful

Role OF Stress and IVF

Dr. Richa Sharma 92% (216 ratings)
MD - Obstetrtics & Gynaecology, MBBS, FNB Reproductive Medicine, MRCOG
IVF Specialist, Mumbai
Role OF Stress and IVF
Stress, anxiety, and depression have been linked to lower IVF outcomes, and psychological intervention improves the chance of success. Paying attention to these factors will also improve interactions ofpatients and staff, and will help adjustment to the stresses of child rearing.Multiple pregnancies have been shown to cause considerable personal and marital stress. Early intervention may enhance the long-term well-being of these families.
1 person found this helpful

In Vitro Fertilization (IVF) - What Indicates That You Need It?

Dr. Nalini Gupta 92% (260 ratings)
M.Sc, MD, MBBS
IVF Specialist, Delhi
In Vitro Fertilization (IVF) - What Indicates That You Need It?
With infertility on the rise due to various reasons, in-vitro fertilization is one of the most effective solutions. This is gaining wide acceptance across the society and medical fraternity. Read on to know more about why IVF and how it is done. Causes of infertility: Advanced maternal age: More and more women choosing education and career over marriage and family. There are many women who are not even thinking of having children up until their 30s. Biologically though, the quality of egg deteriorates with age, and women beyond 35 have difficulty conceiving naturally. Altered lifestyle including exposure to chemicals and pollutants, which has led to overall decline in the health of individuals. Societal changes like urbanization and formation of nuclear families Increased stressors in all spheres of life, which is affecting the quality of sperm and egg Lifestyle diseases including obesity, diabetes, and hypertension. These are becoming more prevalent in the younger age groups, and therefore infertility is on the rise in these groups. Lifestyle habits like smoking, alcohol abuse, drug abuse, etc., which are also poorly affecting fertility rates. However, with all these, medical technology is also improving. For those who are faced with infertility due to the above issues, there is a lot of hope in terms of options like IVF which have provided a definitive solution to infertility. Steps of IVF: By definition, in vitro fertilization is when the egg and sperm are fertilized or fused in a glass (vitro is for glass) and then implanted into the womb where it grows further. The first step is to induce ovulation. Fertility medicines are given and hormone levels are monitored to ensure egg release happens. Normally, the ovaries produce only one egg. However, with IVF, the ovary is made to produce multiple eggs, so that the chances of fertility is increased. The egg is then retrieved and moved into an incubator. Sperm sample is obtained either from the partner or a donor, and the healthiest sperm is chosen for fertilization. The sperm and the egg are then allowed to fertilize in the incubator A healthy fertilized embryo is then transferred into the womb. The woman is advised bed rest for about 1 to 2 days. Indications: Blocked fallopian tubes, which do not allow for the sperms to travel up to the uterus Advanced maternal age, women of more than 30 years of age, this is an effective option. Uterine scarring or endometriosis caused infertility can also be managed through IVF
1 person found this helpful

Popular Questions & Answers

I Want to ask about my sister in law she is suffering from pregnancy problem. What is the difference between IVF & IUI fertility. How can she choose which one is beneficial for her.

Dr. Richika Sahay Shukla 92% (338 ratings)
DNB (Obstetrics and Gynecology), MBBS
IVF Specialist, Delhi
Hello Lybrate user IUI is procedure is a fertility treatment that involving placing sperm inside women uterus to faciliate fertilization. Goal of iui is to increse sperm number to reach to follopian tube subsequently increase chance of fertilization. Most of IUI is useful in low sperm count and decrease sperm motility.In vitro fertilisation (IVF) is a process of fertilisation where an egg is combined with sperm outside the body, in vitro ("in glass"). The process involves monitoring and stimulating a woman's ovulatory process, removing an eggs) from the woman's ovaries and letting sperm fertilise them in a liquid in a laboratory. The fertilised egg undergoes embryo culture for 2–6 days, and is then transferred to the same or another woman's uterus, with the intention of establishing a successful pregnancy. You should need to mention about your personal and medical history and all reports done. It will help us to tell you better solution.
1 person found this helpful

I want to know if an healthy woman go for ivf And she is office going woman daily with public transport Can she continue her office after pregnant by ivf for 2 or 3 month What are the complications of ivf for healthy and fertile lady?

Dr. K.D Nayar 90% (516 ratings)
MD - Obstetrtics & Gynaecology, DGO, Dip.Obst.(Ireland), FICOG
IVF Specialist, Delhi
Patients can carry out daily light activities. Absolute bed rest is not required. She can travel however try to avoid jerky routes..
1 person found this helpful

Hello Doc, I am 27 years old and I am going through IVF treatment, I had 2 failed IUI cycles my AMH value or egg count is very less i.e 1.11 after using many medicines no growth in egg quality and quantity so we want to go for egg donor, can you suggest me which is right option.

Dr. Uma 89% (1487 ratings)
MS- Gynaecology, MBBS
Gynaecologist, Delhi
Ya if no egg form after medication you can go for doner egg. If possible ask Dr. for icsi. It increase chance of fertilisation even if your single egg is form.

Health Quizzes

What is the difference between IUI and IVF?

Care Ivf 92% (24 ratings)
MD - Obstetrtics & Gynaecology, Advanced Infertility
IVF Specialist, Kolkata
IUI treatment is more affordable than the IVF treatment. True or False. Take this quiz to know now!
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42 people took this quiz

Treatment Of Infertility With IVF!

Care Ivf 92% (24 ratings)
MD - Obstetrtics & Gynaecology, Advanced Infertility
IVF Specialist, Kolkata
IVF can increase the chance of having twins. True or false? Take this quiz to know more.
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Diet - How It Affects IVF Results?

Care Ivf 92% (24 ratings)
MD - Obstetrtics & Gynaecology, Advanced Infertility
IVF Specialist, Kolkata
Protein rich foods help increase the chances of successful IVF fertilization. True or false? Take the quiz to know now.
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22 people took this quiz

All about IVF

Care Ivf 92% (24 ratings)
MD - Obstetrtics & Gynaecology, Advanced Infertility
IVF Specialist, Kolkata
A full course of IVF treatments can take about 2 months to complete. True or False. Take this to know now!
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152 people took this quiz

Fallopian Tube blockage and IVF

Dr. Purnima 92% (15 ratings)
MBBS, MD - Obstetrics & Gynaecology
Gynaecologist, Delhi
Women with blocked fallopian tubes can never conceive. True or false? Take this quiz to know more.
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35 people took this quiz

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