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Overview

In Vitro Fertilization: Cost, Procedure, Recovery, Risk & Complication

In-Vitro Fertilization (IVF) consists of a series of procedures that are used for the treatment of genetic or fertility problems, while assisting the conception of a child. One of the most effective forms of assisted reproductive technology, IVF procedures can be conducted using a woman’s own eggs and her partner’s sperm. It can also be done by taking the eggs, sperm or embryos from a known or unknown donor. There are some cases where a gestational carrier (a woman with an embryo implanted in the uterus) can be used.

During IVF, mature eggs are retrieved from a woman’s ovaries and fertilized with the sperms in the lab. Once it has been fertilised, the egg or eggs are implanted back in the uterus. A cycle of IVF can take about 2 weeks.

Indication

One may have to undergo an IVF treatment in the following conditions:

  • If a woman’s fallopian tubes are blocked or damaged
  • If ovulation is infrequent/absent, or there are few eggs available for fertilization
  • Loss of normal functions of the ovary before reaching the age of 40
  • A previous treatment of tubal ligation, where the fallopian pipes have been cut/blocked permanently. In this case, one can opt for IVF instead of tubal ligation reversal.
  • Poor mobility, abnormality in sperm size/shape, or below average concentration of sperm of the male partner
  • If you have the conditions of endometriosis (uterine tissue will implant and grow outside the uterus) or uterine fibroids
  • Unexplained fertility or a genetic disorder

Pre Procedure

Before beginning the process of IVF, both the partners may have to go through certain pre-procedure screenings such as:

  • Ovarian reserve testing, for determining the quality and the quantity of the eggs. The concentration of estrogen, follicle stimulating hormone as well as the antimullerian hormone in your blood is checked by your doctor in the initial days of the menstrual cycle. These test results may help in predicting the response of your ovaries to fertility medications.
  • Analysis of the semen of the male partner
  • Screening for any infectious disease like HIV
  • A mock transfer of the embryo for determining the depth of the uterine cavity and the technique that may work best for you
  • An examination of the uterine cavity that may involve sonohysterography (fluid is injected in the uterus through the cervix and an ultrasound creates images of the uterine cavity) or hysteroscopy
  • Some serious question like the numbers of embryos that will be transferred, what needs to be done with the extra embryos, how to handle a multiple pregnancy, and the complications that may occur with donor eggs and sperms or a gestational carrier have to be discussed.

During Procedure

IVF treatment involves the following steps:

  • Ovulation induction, where synthetic hormones stimulate the ovaries for producing multiple eggs. You have to be under several medications for a week or two before the eggs are ready for retrieval. Vaginal ultrasound or blood tests are examined by the doctor to determine it.
  • Egg retrieval, through a transvaginal ultrasound. In this process, an ultrasound probe is inserted in the vagina for the identification of follicles. A thin needle is guided through the ultrasound guide to reach the vagina for collecting the eggs. The laparoscopy method can also be used for the same.
  • Sperm retrieval through masturbation or testicular aspiration in case the partner’s sperm is being used
  • The next step is fertilization either by insemination (sperm and eggs are incubated overnight) or Intracytoplasmic sperm injection (ICSI), where a single sperm is injected directly in a mature egg.
  • Embryo transfer is next step performed at the doctor’s clinic. It takes place two to six days after the retrieval of the eggs.

Post Procedure

Once the embryo has been transferred, you can go back to your regular schedule. However, your ovaries may be enlarged for a few days, so it is advisable to avoid any vigorous activity that may cause discomfort.

The side effects of post treatment may involve:

  • Passing of a small amount of clear/bloody fluid after the procedure, which is caused because the cervix is swabbed before the transfer of the embryo
  • Mild bloating and cramping
  • Constipation
  • Breast tenderness because of the high levels of estrogen

In case you have a moderate or severe pain after the transferring of the embryo, consult your doctor who will evaluate your condition. Any indication of a complication like an infection pr ovarian torsion can be examined and treated.

Risk & Complication

An IVF procedure may bring along with it certain risks and complications like:

  • Multiple births if more than one embryo has been implanted in the uterus. Multiple foetuses can often lead to premature delivery or a low birth weight of the newborn.
  • The frequent injection of fertility drugs to induce ovulation may lead to ovarian hyperstimulation syndrome, a condition where the ovaries become painful and swollen.
  • Using an aspirating needle for collecting eggs may lead to bleeding, damage or infection in the bowel, bladder or a blood vessel.
  • In some cases, there may be chances of an ectopic pregnancy. This is a condition where the fertilised egg will implant outside your uterus, generally in the fallopian tube. The egg would not be able to survive outside the uterus and the pregnancy will not be possible to be continued.
  • Miscarriage or birth defects
  • There may be a possible connection between some medications used in IVF and a specific type of ovarian tumor, though there have not been enough cases to support it.
  • The procedure of IVF can be physically, emotionally as well as financially draining, leading to stress.

More Info

Make sure that you continue having the medications after the embryo transfer has been successfully completed. It is better to avoid travelling during this period. It is generally after 2 weeks after the embryo transfer that you have to go for a pregnancy test. It is important not to be stressed during this phase, but be optimistic and occupied. Also, the pregnancy test must be conducted by a doctor at the clinic and not by yourself at home.

The cost of an IVF treatment may vary from Rs. 10,000 – Rs. 70,000, depending on your condition.

Popular Health Tips

Myths About IVF You Should Stop Believing Right Now!

Dr. Nalini Gupta 88% (225 ratings)
M.Sc, MD, MBBS
IVF Specialist, Delhi
Myths About IVF You Should Stop Believing Right Now!
In vitro fertilization or IVF is deemed as one of the wonder treatments for couples who are facing infertility issues. Whether it is due to poor sperm quality of blocked fallopian tubes, IVF has proven to be a safe and effective solution. However, like with all new techniques, IVF also has some myths which need to be understood before signing up for the procedure. With so much at stake in terms of finances and time, understanding the process will help set realistic expectations and improve the success rate of IVF. Myth 1: High success rate. While IVF has very high success rates, some women just fail to get pregnant. This could be about 5% of the women and may not be attributable to any particular cause. Each woman responds differently, and failure to conceive through IVF could be due to no explainable cause. What is interesting is that though the first attempt failed, subsequent attempts may be successful. Failing the first cycle does not mean failure in subsequent cycles. Also, success rate differs from clinic to clinic, and so choose one which has a proven track record and good success rates. It should not just have good doctors but also the essential technology and infrastructure to support the IVF technique. Myth #2: IVF leads to multiple births. While achieving multiple births is easier through IVF, it always does not lead to multiple births. Multiple embryos are implanted, only to improve the chances of success. It does not necessarily translate into multiple births. In women over 38 years of age, it is mandatory to only transfer a single embryo as multiple births are very likely to be complicated. Myth #3: Rest and time off work. It is believed that IVF has a higher success rate with proper rest and time off work. Rest is definitely required the first few days after embryo transplant but it definitely later assumes a normal course of things. It is not that too much time off work is required, just because you had an IVF. Your body might be different and require more rest, but that could have been the case even with a normal pregnancy. Myth #4: The medications with IVF are going to have lots of side effects. While the hormones given to promote egg release do have their side effects of making you feel moody and emotional, it is only transient. Once the egg release happens, fertilization is done, and embryo transplant is done, then things should settle down. The effects should wear down once the embryo is implanted and then things should settle down. Of course, pregnancy brings its own hormonal changes, which will run their course through pregnancy.

Understand The Difference Between IVF Vs Tubal Ligation Reversal

Best Fertility Centre In India
IVF Specialist, Chennai
Understand The Difference Between IVF Vs Tubal Ligation Reversal
In vitro fertilization (IVF) includes empowering the woman with medicines, taking various eggs from her ovaries, fertilizing them with her partner s sperm, and inserting a portion of the subsequent embryos into her uterus with the trust that one will form into a fetus. Tubal ligation reversal, on the other hand, requires a laparotomy, which needs a much bigger entry point on the abdomen, usually around four to six fingers long. Since the skin, each of the muscles, and different tissues of the stomach must be sliced through, there is extensively more uneasiness and a longer recovery time required after the surgery, when compared with a laparoscopic surgery, for example, with a tubal ligation. Here are a few common differences: Sperm quality: The male partner needs a sperm test before basic procedures of either of the two. In case that the sperm quality is great, then the couple could consider proceeding. In case that the sperm quality is poor, in vitro treatment is the better alternative. With IVF, poor sperm quality is effectively overcome. Tubal status: The length of the remaining tubal stumps after tubal ligation is an important aspect. The more extended the two remaining stumps are on each side, the better and more effective is the pregnancy. The shorter the stumps, the lower are the odds for pregnancy. Status of other pelvic conditions: Pelvic endometriosis or any scar tissue in the range of the tubes or ovaries would diminish the chance for accomplishment after tubal ligation reversal. Although, IVF pregnancy achievement rates are usually not influenced by these conditions. Along these lines, in vitro fertilization is most likely a superior alternative in women with noteworthy endometriosis or pelvic scar tissue. Female age: Chances for pregnancy with either tubal ligation or IVF decrease in the mid to late thirties and significantly reduce at the age of thirty-eight. By age forty-three or forty-four, not many women will have the capacity to have a baby using either approach. Egg amount and quality: A few women have a decrease in either egg amount or quality prior in life than anticipated. In this manner, the woman s ovarian capacity needs to be tested before a choice is made in regards to whether to continue with either tubal ligation or in-vitro fertilization. AMH levels, ovarian antral follicle number, and day 3 FSH levels are generally done to evaluate ovarian capacity or hold. Doctor intervention: The greatest favorable position of tubal ligation reversal over IVF is that once the woman has experienced the surgery she ideally will not require any medication through the doctor, for example, medications or systems, keeping in mind the end goal to get pregnant.

How Endometrial Scratching and IVF Can Help You Get Pregnant?

Dr. Sameer Pahlajani 89% (10 ratings)
MBBS
IVF Specialist, Raipur
How Endometrial Scratching and IVF Can Help You Get Pregnant?
In vitro fertilisation (IVF) is a medical procedure followed for those women or couples suffering from infertility or for certain specific genetic problem. In the normal course, women or couples experience positive results within a few IVF cycles. However, in spite of reasonable pregnancy rates, some women may require few more cycles to achieve pregnancy. In such cases, in order to ensure a healthy pregnancy, the gynecologist may suggest the women undergo Endometrial Scratching before IVF. Endometrium explained in brief: The uterus is located in the pelvic region and it is in the size and shape of a pear. The inner cavity of the womb or uterus is protected by the tissue lining called endometrium, also called endometrial. The endometrium plays a significant role in supporting the pregnancy. The enhanced success of achieving pregnancy: The endometrial scratching procedure is a very simple one, which is resorted, so as to improve the results of IVF procedure. In this procedure, the gynecologist uses a very fine catheter and makes a small scratch on the endometrial lining. In fact, the scratch causes a kind of inflammatory reaction in the uterus. This inflammatory reaction induces the endometrium to be highly receptive to embryos during the successive menstrual cycle. This added receptivity enhances the success of pregnancy during the next menstrual cycle. Considering the higher level of success in achieving pregnancy, the endometrial scratching procedure has gained popularity in the IVF procedure. However, some of the other issues related to endometrial scratching may be as follows: Endometrial scratching optimises the uterine lining and thereby, makes it easier to continue the embryo implanting procedure. Normally, before the endometrial scratching procedure, the gynecologist may suggest endometrial biopsy. The endometrial procedure is usually suggested for those women who had two or more unsuccessful IVF procedures, despite having good quality embryos. However, in some cases, depending on the health of the patient and various other factors, the gynecologist may suggest this endometrial scratching at the very first IVF procedure. This procedure can be availed either for fresh embryos of the couple or frozen embryos or for the donor egg. Although this is a part of a surgical procedure; endometrial scratching is very simple and painless and it is done without administering anesthesia. The procedure does not require any hospitalisation. In fact, the patient can go home soon after the procedure. Except for a few pain killers, this procedure does not require any extensive medication. This is a safe and easy procedure. Neither does it lead to any side effects, nor is the procedure burdensome for your wallet. Many couples have been benefited by this endometrial scratching procedure.
1 person found this helpful

Natural Cycle IVF

Dr. Richika Sahay Shukla 88% (166 ratings)
DNB (Obstetrics and Gynecology), MBBS
IVF Specialist, Delhi
Natural Cycle IVF
What is Natural Cycle IVF? Natural cycle IVF involves collecting and fertilising the one egg that you release during your normal monthly cycle. No fertility drugs are used in this treatment. Is Natural Cycle IVF For Me? It may be worth discussing this treatment option with your clinician if your periods are fairly regular and you are ovulating normally, but: you are unable to take fertility drugs (for example, cancer patients or those whose clinician has suggested that they are at risk of OHSS ovarian hyper-stimulation a dangerous over-reaction to fertility drugs) because for personal or religious beliefs you do not wish to have surplus eggs or embryos destroyed or stored. How Does Natural Cycle IVF For Me? The treatment is the same as conventional IVF, but without the fertility drugs that are used to stop natural egg production and hormones that boost the supply of eggs. As your ovaries are nt being artificially stimulated, you don t need to rest as you would after conventional IVF. If your treatment is unsuccessful, you can try again sooner if you wish.

Infertility - Treatments Available For Men & Women!

Dr. Ashwini Talpe 95% (3264 ratings)
MBBS, MS - Obstetrics & Gynecology, Fellowship in Infertility (IVF Specialist)
Gynaecologist, Aurangabad
Infertility - Treatments Available For Men & Women!
Infertility is a condition which is characterized by the inability to have a baby for over a year in spite of having planned and unprotected sex. It is a pretty common phenomenon for both men and women. However, there are several treatments available for both the sexes to help them recover from this problem. Here are some of the most common treatments available for infertility: For Men 1. Changing your lifestyle: Certain factors in your lifestyle, which may cause you to be infertile include the medications you take, lack of exercise or not having intercourse frequently enough or not at the right times. The solution for these problems is simply incorporating certain changes in your daily life such as exercising more, sticking to a healthy diet or having intercourse more often at the right times. 2. Sperm retrieval: Sperm retrieval is the technique used when you cannot ejaculate or when there is hardly any sperm present in your semen. It is also used in case of a low sperm count. For Women 1. Intrauterine insemination: Intrauterine insemination is a process in which healthy sperm cells are put into the uterus so that the egg gets fertilized when it is released. The sperm cells have to be inserted at the time when your ovaries release eggs; therefore it is crucial to know your menstrual cycle as well as how fertility drugs are affecting it. 2. Fertility drugs: Fertility drugs are used to stimulate ovulation. This is done by administering medications which either regulate or cause ovulation to occur. There are several types of fertility drugs, so you should talk to your doctor about which should be the best for you. 3. Hysteroscopic surgery: This is a last resort, which is taken only when there are significant problems such as intrauterine scar tissue, uterine septum or endometrial polyps. 4. IVF: IVF is an assisted reproductive technology. During IVF, the sperm is at first retrieved, after which fertility medications are given to the woman so that the egg can be retrieved. Finally, the egg is fertilized on a laboratory dish and injected back into the mother or a surrogate mother.
5 people found this helpful

Popular Questions & Answers

I and my husband did not got intercourse yet since married 3 years due to ED problem of my husband. We tried homeopathic allopathic as well as ayurveda. Can I become pregnant with IVF treatment?

Dr. Jayanthi. R. 91% (113 ratings)
MBBS, Certified IVF Specialist, MS - Counselling and Psychotherapy
IVF Specialist, Chennai
Hi, Erectile dysfunction (ED) is more to do with the mind than the body. He can go for an andrologist's opinion and proper counselling since it can be related to some psychological problem from childhood. Only if all this fails, you can go for IVF because, if it happens naturally, you won't have to struggle for the second child. Best wishes.

Please suggest me. IVF ki cost kitne hota h? Please tell me about this Technic and cost.

Dr. Vidya Mahadev Honawad 89% (23 ratings)
MBBS, MD - Obstetrtics & Gynaecology, FCPS
Gynaecologist, Hubli-Dharwad
Cost of ivf is not fixed. It will very patient to patient. But if your wife age is less than 30, with good ovarian reserve, it will come around 1-1.2 lakh. For tech, please check in the you tube. You will get all videos.
1 person found this helpful

I am 40 years old and did one ivf in November 2017 which did not work now the Dr. is telling me to do a operation to remove my fibroid which is 2 mm I also had a massage in 2012 which was 18 weeks. What are my chances of becoming pregnant and giving a normal birth. I am married for 8 yrs.

Dr. Reena Kawatra 93% (4311 ratings)
MBBS, MD - Obstetrtics & Gynaecology
Gynaecologist, Gurgaon
Chances of pregnancy are good if you are given the right Medications for concieving and your fibroid is removed successfully.

I am 47 years old and single parent. I want to have a child through IVF. Please tell me the approximate cost of treatment and success rate?

Dr. Richa Sharma 95% (153 ratings)
MD - Obstetrtics & Gynaecology, MBBS, FNB Reproductive Medicine, MRCOG
Gynaecologist, Mumbai
At 47 years first thing there are chances that eggs of good quality and quantity won't be there so possibility of taking egg donor with IVF cost vary as per state and centre but on an average it can fall between 2-2.5lacs.
1 person found this helpful

We are in the middle of IVF cycle. Two "A "grade embryo transferred on 9.11.17. Today is day 10. As of now my wife is not having any symptoms except morning fever since two days. We are anxious about the result .Doctor told to do beta HCG test on 14.11.17. Whether we can take home pregnancy test before 14.11.17. Is it reliable. Pls advice.

Dr. Richika Sahay Shukla 88% (166 ratings)
DNB (Obstetrics and Gynecology), MBBS
IVF Specialist, Delhi
No, you should do beta hcg test after 13-14 days of egg collection because the hormone produces the embryo and passes to the mother via the placenta. This is the first measurable sign of embryo implantation. During an In Vitro Fertilisation treatment.
1 person found this helpful

Health Quizzes

IVF - Things You Must Know Before Hand!

Ms-Biology, Ph.D Biology
IVF Specialist, Jalandhar
The risks of IVF and age are related. True or false. Take this quiz to know more.
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IVF - Things You Need To Take Care Of!

Ms-Biology, Ph.D Biology
IVF Specialist, Jalandhar
IVF treatment has a risk of ectopic pregnancies. True or false? Take this quiz to know more.
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