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In Vitro Fertilization (IVF) Tips

Increase Your Changes Of Fertility With IMSI!

Dr. K.D Nayar 90% (518 ratings)
MD - Obstetrtics & Gynaecology, DGO, Dip.Obst.(Ireland), FICOG
IVF Specialist, Delhi
Increase Your Changes Of Fertility With IMSI!

Of a million sperms released in one ejaculation, a single sperm manages to fertilize the egg, which grows into an embryo and then a baby. Due to various reasons, when this does not happen, it is termed as infertility and is currently on the rise.

With IVF, couples sometimes go through multiple sessions to ensure fertilization. ICSI or intracytoplasmic sperm injection improved this chance of fertilization. It is where a single sperm is used to fertilize an egg in an artificially controlled environment and then injected into the uterus where it grows further.

The next step in this technique is IMSI, where the chances of successful pregnancy are further enhanced and also promises improved quality of the embryo. IMSI, as it stands for, has “morphologically selected” which means under a highly powerful microscope, the best sperms are selected and then used to fertilize the egg. Morphology stands for shape, and the shape of the sperm is a direct indicator of the sperm quality. This not just ensures good success rate but also ensures the sperm which is used produces a high-quality embryo.


  1. High success rate of fertility
  2. Reliable and efficient method of ART (assisted reproductive technology)
  3. More expensive than traditional IVF methods or ICSI
  4. Requires complex equipment, training, and set-up


  1. Useful in couples who have failed IVF previously
  2. Male infertility with unidentifiable cause
  3. Poor sperm quality

What to expect?

Both partners are prepared both physically and mentally prior to IMSI.

Before the procedure - men:

  1. A screening is first done to decide if the sperms can be used directly
  2. In case of hereditary diseases, a donor is preferred
  3. The first technical step involves sperm collection, either directly or through a donor
  4. Sperms are collected either through masturbation or through a small incision in the testicles
  5. Sperms used could be fresh or frozen; fresh ones may be stored for later use also

Before the procedure – women:

  1. The woman is put on some ovulation therapy to ensure the release of multiple eggs, so a good one is picked. These high doses of hormones ensure multiple eggs are released.
  2. Egg release is monitored through blood and urine tests
  3. They are collected within after 36 hours of release

During the IMSI procedure:

  1. A healthy egg is chosen and placed in a glass container containing hyaluronidase
  2. Sperms are placed in a medium which will slow their movement, which enables picking a good sperm for fertilization
  3. The dual advantage of this is that in addition to a high success rate of fertilization, the quality of the embryo is also assured

In case you have a concern or query you can always consult an expert & get answers to your questions!

1180 people found this helpful

IVF - Facts That Are Actually Myths!

Dr. Apoorva Pallam Reddy 90% (208 ratings)
MBBS, MS - Obstetrics and Gynaecology, DNB (Obstetrics and Gynecology)
Gynaecologist, Bangalore
IVF - Facts That Are Actually Myths!

In-vitro fertilisation (IVF) is one of the popular Assisted Reproductive Technologies (ART) for treating infertility and helping couples to conceive.

But lack of understanding about the IVF treatment has given rise to a number of myths such as:

Myth 1: IVF never fails but is always successful
The success of the procedure depends on a number of factors such as quality and quantity of embryos and age. It is said that chances of conception decreases with age, with women above 40 reporting reduced fertility potential as well as success rate. On the other hand, women below the age of 35 have about 41% chance of getting pregnant.

Myth 2: IVF increases your fertility levels
Instead of making you more fertile, IVF stops your natural fertility cycle. This is usually done through hormones that are taken at the beginning of the process. The aim of such an action is to essentially put an end to your natural fertility process and create in its place an artificial cycle.

Myth 3: It causes you to have triplets or twins
No, it's not necessary for multiple births to take place if you opt for IVF. You can reduce the prospect of having twins or triplets by cutting down on the number of embryos that get inserted into the uterus.

Myth 4: IVF hormone injections make you prone to uncontrollable emotions.
In actuality, IVF hormone injections don't cause you to suffer from out of control emotions but make you happier. This is because they come packed with the female hormone oestrogen, which produce endorphins (brain chemicals) that give you a sense of wellbeing. The wave of emotions that you end up experiencing is a result of the stress and anxiety surrounding the success of a cycle.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5357 people found this helpful

PCOD - How it Affects Your Body?

Dr. Shilpa Bansal Agrawal 93% (369 ratings)
MBBS, MD - Obstetrtics & Gynaecology, DNB, Fellowship in Infertility
Gynaecologist, Mumbai
PCOD - How it Affects Your Body?

PCOD or polycystic Ovary Disorder is one of the most common disorders of hormones among women in the age of reproduction. It is yet not discovered why some women become susceptible to this disease and it is believed to be a genetic disorder. The word “polycystic” refers to multiple cysts and a woman suffering from PCOD has multiple cysts in her ovary. This is due to the imbalance of hormones, which don’t allow the ovary to release eggs every month and these numerous unreleased eggs present in the ovary cause it to become polycystic.

What are the symptoms of PCOD?
The regular release of eggs from the ovaries directs a woman’s fertility and allows her to have a normal menstrual cycle. Therefore, women with PCOD face difficulty in conceiving along with irregular, low and absent periods. Some of the most common symptoms of PCOD include infertility and even miscarriage, elevated insulin levels, high blood pressure, diabetes, acne, unhealthy weight gain and obesity. It also leads to loss of hair from the scalp and excessive growth of hair on the body. This is due to over production of male hormones that lead to male pattern of growth of hair, such as on chest, cheek, chin and inner thighs. The hormonal imbalance leads to weight gain and obesity makes the hormonal imbalance even worse, turning it into a vicious cycle.

How is PCOD diagnosed and treated?
Your gynaecologist would be able to determine whether you have PCOD by checking your symptoms. Then she would recommend you to do a few blood tests along with a pelvic ultrasound scan to confirm whether you have PCOD. Though this disease is not reversible, its symptoms may be reduced or minimised. Most women can lead a trouble-free and healthy life if they take proper precautions at the right time.

It has been pointed in several studies that reduction in weight can help in the improvement of most PCOD symptoms because fat contributes to the production of certain hormones. Your doctor will prepare a treatment plan depending on the aspect from which you are suffering. For instance, if you are suffering from irregular periods, your doctor may prescribe you some contraceptives which can help in restoring normal menstrual cycle. But this treatment is definitely unsuitable for those who are trying to conceive. The infrequent and irregular ovulation can make it difficult to conceive and it can be artificially induced with the aid of medications. So, you must consult a gynaecologist to help your situation.

4586 people found this helpful

Role OF Stress and IVF

Dr. Richa Sharma 92% (216 ratings)
MD - Obstetrtics & Gynaecology, MBBS, FNB Reproductive Medicine, MRCOG
IVF Specialist, Mumbai
Role OF Stress and IVF

Stress, anxiety, and depression have been linked to lower IVF outcomes, and psychological intervention improves the chance of success. Paying attention to these factors will also improve interactions ofpatients and staff, and will help adjustment to the stresses of child rearing.Multiple pregnancies have been shown to cause considerable personal and marital stress. Early intervention may enhance the long-term well-being of these families.  


1 person found this helpful

In Vitro Fertilization (IVF) - What Indicates That You Need It?

Dr. Nalini Gupta 92% (260 ratings)
IVF Specialist, Delhi
In Vitro Fertilization (IVF) - What Indicates That You Need It?

With infertility on the rise due to various reasons, in-vitro fertilization is one of the most effective solutions. This is gaining wide acceptance across the society and medical fraternity. Read on to know more about why IVF and how it is done.

Causes of infertility:
Advanced maternal age: More and more women choosing education and career over marriage and family. There are many women who are not even thinking of having children up until their 30s. Biologically though, the quality of egg deteriorates with age, and women beyond 35 have difficulty conceiving naturally.

  • Altered lifestyle including exposure to chemicals and pollutants, which has led to overall decline in the health of individuals.
  • Societal changes like urbanization and formation of nuclear families
  • Increased stressors in all spheres of life, which is affecting the quality of sperm and egg
  • Lifestyle diseases including obesity, diabetes, and hypertension. These are becoming more prevalent in the younger age groups, and therefore infertility is on the rise in these groups.
  • Lifestyle habits like smoking, alcohol abuse, drug abuse, etc., which are also poorly affecting fertility rates.

However, with all these, medical technology is also improving. For those who are faced with infertility due to the above issues, there is a lot of hope in terms of options like IVF which have provided a definitive solution to infertility.

Steps of IVF: By definition, in vitro fertilization is when the egg and sperm are fertilized or fused in a glass (vitro is for glass) and then implanted into the womb where it grows further.

  • The first step is to induce ovulation. Fertility medicines are given and hormone levels are monitored to ensure egg release happens. Normally, the ovaries produce only one egg. However, with IVF, the ovary is made to produce multiple eggs, so that the chances of fertility is increased.
  • The egg is then retrieved and moved into an incubator.
  • Sperm sample is obtained either from the partner or a donor, and the healthiest sperm is chosen for fertilization. The sperm and the egg are then allowed to fertilize in the incubator
  • A healthy fertilized embryo is then transferred into the womb. The woman is advised bedrest for about 1 to 2 days.


  • Blocked fallopian tubes, which do not allow for the sperms to travel up to the uterus
  • Advanced maternal age, women of more than 30 years of age, this is an effective option.
  • Uterine scarring or endometriosis caused infertility can also be managed through IVF
1 person found this helpful

In Vitro Fertilization: Understanding the Process

Dr. Kinker. Mrinal 85% (10 ratings)
MBBS, MS - General Surgery
General Surgeon, Kota
In Vitro Fertilization: Understanding the Process

What is IVF?

IVF stands for In Vitro Fertilization and is a method of artificial insemination that dramatically increases the chances of pregnancy. It is one of the assisted reproductive technologies methods used as fertility treatment across the world where other methods have had drastic results.

In simpler terms, a man's sperm is inserted in woman's egg using controlled laboratory environment to proceed with fertilization. These embryos are then carefully put back into the mother's uterus after 4 to 5 days of fertilization in incubator in hopes that the embryo would grow in a full baby. The embryo transfer process needs to be carefully done in order for successful fertilization in the mother's womb.

There are many reasons why IVF is conducted:

  1. Poor sperm quality - Males having poor sperm quality are unable to achieve fertilization and increase the chances of conception with their female partners. This is male factor infertility due to which people move towards IVF.
  2. Fallopian tube problems - This is a female factor infertility, in which fallopian tubes either get blocked, or damaged making it complicated and stressful for the embryo to travel to the uterus.

One must approach IVF treatment with patience and a willingness to comply with all the tenets that the treatment is built upon. IVF clinics may vary the treatment a little according to what the patient's condition demands and different clinics may have different methods. The basic methods of IVF treatment however, remain the same. The first step to the treatment is to find the right clinic which complies with factors like availability of resources, cost and quality of treatment. After deciding the clinic, the next step is to understand that IVF treatment happens in cycles and the success rate of conception varies. Patients must also be ready to face any disappointment.

Here’s the short version of the steps involved in an IVF treatment cycle:

  1. Ovarian stimulation. Your doctor prescribes a course of drugs for you to take to stimulate your ovaries into hopefully producing 12 to 15 mature eggs.
  2. Monitoring of your drug response. To monitor the progress of your ovarian stimulation you undergo an ultrasound examination and blood tests.
  3. Egg maturation. Two days before your eggs are due to be collected you have a hormone injection, which triggers maturation of the eggs.
  4. Egg collection. You receive a light general anaesthetic for this simple, short procedure, and your doctor retrieves your eggs using an ultrasound-guided technique.
  5. Sperm production. On the day of egg collection, your partner provides a sperm sample.
  6. Fertilisation. The embryologist puts sperm and eggs together in the lab and, if all goes well, the eggs fertilise and early embryo development begins.
  7. Embryo transfer. Two to five days after egg collection, your doctor places one or two embryos in your uterus. Frozen transfer can be planned after a gap of 1 month.
  8. Embryo freezing. If you have additional embryos suitable for use, they can be frozen and kept for future transfers. Also, frozen embryos are available.
  9. Pregnancy test. About two weeks after embryo transfer you have a blood test to find out whether the treatment worked.
    • If the test is positive, you have your first pregnancy scan two weeks later.
    • If the test is negative, you and your partner need to talk to your doctor and decide whether to try the treatment again.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3286 people found this helpful

Indications Of IVF- Know The Signs To A New Life!

Dr. Abhishek S Parihar 92% (46 ratings)
Fellowship in Reproductive Medicine, MS - Obstetrics and Gynaecology, MBBS
IVF Specialist, Ghaziabad
Indications Of IVF- Know The Signs To A New Life!

The advancement in the field of medicine is enormous, and with each passing day, the promises it offers in providing solutions is growing. Apparently, the treatment options for infertility too have grown exponentially, and one such option is the IVF.

IVF stands for In vitro fertilization which is a system in which treated sperm are either injected or placed into the egg in a petri dish to accomplish fertilization. If the egg fertilizes, the resultant embryos are implanted into the woman’s uterus. Formerly IVF was done for women with issues in the fallopian tube, but there are some other implications of IVF as well in more recent times as discussed below.

  1. Infertility- IVF is the chosen method of treatment in the case of Infertility that is not treatable by therapy, or infertility which can be more favorably be treated with IVF than using any other procedures. IVF can be provided by the demand of a couple for any form of infertility if there are no contraindications.
  2. Tubal disease- Women who have blocked fallopian tubes opted previously for operation have now started using IVF as a better choice of treatment. But in case of patients who have hydrosalpinx, the tubes may have to be removed or interrupted through surgery to maximize the success rates of IVF.
  3. Male factor- In cases of male infertility issues, where there is a deficiency or defect in the quality of sperm or it has trouble penetrating the egg, IVF can be the solution. Through IVF and intracytoplasmic sperm injection (ICSI), such cases can be treated.
  4. Immunological sterility- Immunological infertility refers to miscarriage or infertility caused by immune attacks on the tissues of the reproductive system. It is the outcome of the disorder of immune system which pairing up with its antibodies corrupts female eggs and male sperms. If the low motion of spermatozoids is perceived in the partner, and artificial insemination doesn’t yield any returns, extracorporeal fertilization is suggested.
  5. Endometriosis- It is a phenomenon where menstrual period, becomes far worse than customary accompanied by pain with bowel movements or urination. Patients who have endometriosis, often have tubal involvement or ovarian cysts called endometrioma and will benefit from IVF.
  6. Ovulatory dysfunction- Ovulatory Dysfunction is the single-most common cause of female infertility and indicates a difficulty with ovulation that is the monthly release of an egg. When a woman is incapable of ovulation, she can't get pregnant as there is no egg to be fertilized. In patients with PCOS that is polycystic ovarian disease and other ovulatory obstacles, IVF can be recommended.
  7. Unexplained infertility- Patients with no apparent cause for their infertility or other uterine dysfunctionality can get help from IVF too.

Thus one can consider the possibility of IVF in numerous situations causing infertility. Also when the above indications are noticed opting for an IVF can be the best choice. In this case, it is essential to consult with a gynecologist to determine if it will be beneficial in the given circumstance before starting with the procedure.

Embryo Freezing

Dr. Richika Sahay Shukla 91% (341 ratings)
DNB (Obstetrics and Gynecology), MBBS
IVF Specialist, Delhi
Embryo Freezing

Embryo Freezing

Embryo freezing is a technique that is recommended when high-quality embryos remain after embryo transfer. These embryos remain frozen until the patient is ready to use them. If patients have completed their families, they have the option to donate these frozen embryos to research, another couple, or training; the embryos can also be discarded.

Egg Freezing

Dr. Richika Sahay Shukla 91% (341 ratings)
DNB (Obstetrics and Gynecology), MBBS
IVF Specialist, Delhi
Egg Freezing

Egg Freezing

Egg freezing allows a woman to preserve her fertility until she is ready to start her family. During an egg-freezing cycle, a patient will go through many of the same steps that are involved in a typical IVF cycle: ovulation stimulation, ultrasound monitoring, and egg retrieval. After egg retrieval, the eggs will be cultured for a few hours and then frozen the same day for future use.

2 people found this helpful

Embryo Adoption and Freezing

Dr. Richa Sharma 92% (216 ratings)
MD - Obstetrtics & Gynaecology, MBBS, FNB Reproductive Medicine, MRCOG
IVF Specialist, Mumbai
Embryo Adoption and Freezing

This is the success story of adopting an embryo which was frozen for 24 years.

Its no Less than a miracle but it also proves that THERE IS ALWAYS A HOPE 

What we consider end may be a begining

Here via this platform we are sharing success story with our readers

The baby that was conceived just 18 months after its mother: Woman, 26, gives birth to baby girl from a donated embryo that was frozen for 24 YEARS - the longest ever Emma Wren, born on November 25 this year, was conceived in 1992 Her adoptive mother Tina Gibson, 26, was conceived in 1991 Tina married her husband Benjamin when she was 19 and he was 26 because he has cystic fibrosis (CF), a fatal disease with a life expectancy in the 30s Fertility is often an issue with CF so they decided they would adopt, and they fostered several children to prepare for itThen they heard they could adopt an embryo and have a pregnancy experience

The embryo was cryopreserved until March this year, making it 24 years frozen It is the longest time an embryo has been frozen, after one in Virginia which was frozen for 19 years and a few months Experts say this successful birth 'suggests the shelf life of an embryo could be infinite'  


  •  Couples who go through IVF tend to have extra embryos leftover, which are frozen and stored for later use. Eventually, when families decide they don't want any more children, they have to decide what to do with the leftover frozen embryos.
  • IVF couples have a few options for their left over embryos:-
  • donate the embryos to research 
  • thaw them and let them die
  • keep them frozen donate them to a couple who can't conceive
2 people found this helpful

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