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In Vitro Fertilization (IVF) Tips

Understanding the Steps of IVF

Dr. Sameer Pahlajani 89% (10 ratings)
MBBS
IVF Specialist, Raipur
Understanding the Steps of IVF

What is IVF?

IVF stands for In Vitro Fertilization and is a method of artificial insemination that dramatically increases the chances of pregnancy. It is one of the assisted reproductive technologies methods used as fertility treatment across the world where other methods have had drastic results.

In simpler terms, a man's sperm is inserted in woman's egg using controlled laboratory environment to proceed with fertilization. These embryos are then carefully put back into the mother's uterus after 4 to 5 days of fertilization in incubator in hopes that the embryo would grow in a full baby. The embryo transfer process needs to be carefully done in order for successful fertilization in the mother's womb.

There are many reasons why IVF is conducted:

  1. Poor sperm quality - Males having poor sperm quality are unable to achieve fertilization and increase the chances of conception with their female partners. This is male factor infertility due to which people move towards IVF.
  2. Fallopian tube problems - This is a female factor infertility, in which fallopian tubes either get blocked, or damaged making it complicated and stressful for the embryo to travel to the uterus.

One must approach IVF treatment with patience and a willingness to comply with all the tenets that the treatment is built upon. IVF clinics may vary the treatment a little according to what the patient's condition demands and different clinics may have different methods. The basic methods of IVF treatment however, remain the same. The first step to the treatment is to find the right clinic which complies with factors like availability of resources, cost and quality of treatment. After deciding the clinic, the next step is to understand that IVF treatment happens in cycles and the success rate of conception varies. Patients must also be ready to face any disappointment.

Here’s the short version of the steps involved in an IVF treatment cycle:

  1. Ovarian stimulation. Your doctor prescribes a course of drugs for you to take to stimulate your ovaries into hopefully producing 12 to 15 mature eggs.
  2. Monitoring of your drug response. To monitor the progress of your ovarian stimulation you undergo an ultrasound examination and blood tests.
  3. Egg maturation. Two days before your eggs are due to be collected you have a hormone injection, which triggers maturation of the eggs.
  4. Egg collection. You receive a light general anaesthetic for this simple, short procedure, and your doctor retrieves your eggs using an ultrasound-guided technique.
  5. Sperm production. On the day of egg collection, your partner provides a sperm sample.
  6. Fertilisation. The embryologist puts sperm and eggs together in the lab and, if all goes well, the eggs fertilise and early embryo development begins.
  7. Embryo transfer. Two to five days after egg collection, your doctor places one or two embryos in your uterus. Frozen transfer can be planned after a gap of 1 month.
  8. Embryo freezing. If you have additional embryos suitable for use, they can be frozen and kept for future transfers. Also, frozen embryos are available.
  9. Pregnancy test. About two weeks after embryo transfer you have a blood test to find out whether the treatment worked.
    • If the test is positive, you have your first pregnancy scan two weeks later.
    • If the test is negative, you and your partner need to talk to your doctor and decide whether to try the treatment again.

Myths About IVF You Should Stop Believing Right Now!

Dr. Nalini Gupta 88% (225 ratings)
M.Sc, MD, MBBS
IVF Specialist, Delhi
Myths About IVF You Should Stop Believing Right Now!

In vitro fertilization or IVF is deemed as one of the wonder treatments for couples who are facing infertility issues. Whether it is due to poor sperm quality of blocked fallopian tubes, IVF has proven to be a safe and effective solution. However, like with all new techniques, IVF also has some myths which need to be understood before signing up for the procedure. With so much at stake in terms of finances and time, understanding the process will help set realistic expectations and improve the success rate of IVF.

Myth 1: High success rate. While IVF has very high success rates, some women just fail to get pregnant. This could be about 5% of the women and may not be attributable to any particular cause. Each woman responds differently, and failure to conceive through IVF could be due to no explainable cause. What is interesting is that though the first attempt failed, subsequent attempts may be successful. Failing the first cycle does not mean failure in subsequent cycles. Also, success rate differs from clinic to clinic, and so choose one which has a proven track record and good success rates. It should not just have good doctors but also the essential technology and infrastructure to support the IVF technique.

Myth #2: IVF leads to multiple births. While achieving multiple births is easier through IVF, it always does not lead to multiple births. Multiple embryos are implanted, only to improve the chances of success. It does not necessarily translate into multiple births. In women over 38 years of age, it is mandatory to only transfer a single embryo as multiple births are very likely to be complicated.

Myth #3: Rest and time off work. It is believed that IVF has a higher success rate with proper rest and time off work. Rest is definitely required the first few days after embryo transplant but it definitely later assumes a normal course of things. It is not that too much time off work is required, just because you had an IVF. Your body might be different and require more rest, but that could have been the case even with a normal pregnancy.

Myth #4: The medications with IVF are going to have lots of side effects. While the hormones given to promote egg release do have their side effects of making you feel moody and emotional, it is only transient. Once the egg release happens, fertilization is done, and embryo transplant is done, then things should settle down. The effects should wear down once the embryo is implanted and then things should settle down. Of course, pregnancy brings its own hormonal changes, which will run their course through pregnancy.

Understand The Difference Between IVF Vs Tubal Ligation Reversal

Best Fertility Centre In India
IVF Specialist, Chennai
Understand The Difference Between IVF Vs Tubal Ligation Reversal

In vitro fertilization (IVF) includes empowering the woman with medicines, taking various eggs from her ovaries, fertilizing them with her partner’s sperm, and inserting a portion of the subsequent embryos into her uterus with the trust that one will form into a fetus. 

Tubal ligation reversal, on the other hand, requires a laparotomy, which needs a much bigger entry point on the abdomen, usually around four to six fingers long. Since the skin, each of the muscles, and different tissues of the stomach must be sliced through, there is extensively more uneasiness and a longer recovery time required after the surgery, when compared with a laparoscopic surgery, for example, with a tubal ligation. 

Here are a few common differences: 

  1. Sperm quality: The male partner needs a sperm test before basic procedures of either of the two. In case that the sperm quality is great, then the couple could consider proceeding. In case that the sperm quality is poor, in vitro treatment is the better alternative. With IVF, poor sperm quality is effectively overcome. 
  2. Tubal status: The length of the remaining tubal stumps after tubal ligation is an important aspect. The more extended the two remaining stumps are on each side, the better and more effective is the pregnancy. The shorter the stumps, the lower are the odds for pregnancy. 
  3. Status of other pelvic conditions: Pelvic endometriosis or any scar tissue in the range of the tubes or ovaries would diminish the chance for accomplishment after tubal ligation reversal. Although, IVF pregnancy achievement rates are usually not influenced by these conditions. Along these lines, in vitro fertilization is most likely a superior alternative in women with noteworthy endometriosis or pelvic scar tissue. 
  4. Female age: Chances for pregnancy with either tubal ligation or IVF decrease in the mid to late thirties and significantly reduce at the age of thirty-eight. By age forty-three or forty-four, not many women will have the capacity to have a baby using either approach. 
  5. Egg amount and quality: A few women have a decrease in either egg amount or quality prior in life than anticipated. In this manner, the woman’s ovarian capacity needs to be tested before a choice is made in regards to whether to continue with either tubal ligation or in-vitro fertilization. AMH levels, ovarian antral follicle number, and day 3 FSH levels are generally done to evaluate ovarian capacity or hold. 
  6. Doctor intervention: The greatest favorable position of tubal ligation reversal over IVF is that once the woman has experienced the surgery she ideally will not require any medication through the doctor, for example, medications or systems, keeping in mind the end goal to get pregnant.

How Endometrial Scratching and IVF Can Help You Get Pregnant?

Dr. Sameer Pahlajani 89% (10 ratings)
MBBS
IVF Specialist, Raipur
How Endometrial Scratching and IVF Can Help You Get Pregnant?

In vitro fertilisation (IVF) is a medical procedure followed for those women or couples suffering from infertility or for certain specific genetic problem. In the normal course, women or couples experience positive results within a few IVF cycles. However, in spite of reasonable pregnancy rates, some women may require few more cycles to achieve pregnancy. In such cases, in order to ensure a healthy pregnancy, the gynecologist may suggest the women undergo Endometrial Scratching before IVF. 

Endometrium explained in brief: 

The uterus is located in the pelvic region and it is in the size and shape of a pear. The inner cavity of the womb or uterus is protected by the tissue lining called endometrium, also called endometrial. The endometrium plays a significant role in supporting the pregnancy. 

The enhanced success of achieving pregnancy: 

The endometrial scratching procedure is a very simple one, which is resorted, so as to improve the results of IVF procedure. In this procedure, the gynecologist uses a very fine catheter and makes a small scratch on the endometrial lining. In fact, the scratch causes a kind of inflammatory reaction in the uterus. This inflammatory reaction induces the endometrium to be highly receptive to embryos during the successive menstrual cycle. This added receptivity enhances the success of pregnancy during the next menstrual cycle. 

Considering the higher level of success in achieving pregnancy, the endometrial scratching procedure has gained popularity in the IVF procedure. However, some of the other issues related to endometrial scratching may be as follows: 

  1. Endometrial scratching optimises the uterine lining and thereby, makes it easier to continue the embryo implanting procedure. Normally, before the endometrial scratching procedure, the gynecologist may suggest endometrial biopsy. 
  2. The endometrial procedure is usually suggested for those women who had two or more unsuccessful IVF procedures, despite having good quality embryos. However, in some cases, depending on the health of the patient and various other factors, the gynecologist may suggest this endometrial scratching at the very first IVF procedure. This procedure can be availed either for fresh embryos of the couple or frozen embryos or for the donor egg. 
  3. Although this is a part of a surgical procedure; endometrial scratching is very simple and painless and it is done without administering anesthesia. The procedure does not require any hospitalisation. In fact, the patient can go home soon after the procedure. Except for a few pain killers, this procedure does not require any extensive medication. 

This is a safe and easy procedure. Neither does it lead to any side effects, nor is the procedure burdensome for your wallet. Many couples have been benefited by this endometrial scratching procedure.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2 people found this helpful

Natural Cycle IVF

Dr. Richika Sahay Shukla 88% (167 ratings)
DNB (Obstetrics and Gynecology), MBBS
IVF Specialist, Delhi
Natural Cycle IVF

What is Natural Cycle IVF?

Natural cycle IVF involves collecting and fertilising the one egg that you release during your normal monthly cycle. No fertility drugs are used in this treatment.

Is Natural Cycle IVF For Me?

It may be worth discussing this treatment option with your clinician if your periods are fairly regular and you are ovulating normally, but:

you are unable to take fertility drugs (for example, cancer patients or those whose clinician has suggested that they are at risk of OHSS “ ovarian hyper-stimulation “ a dangerous over-reaction to fertility drugs) because for personal or religious beliefs you do not wish to have surplus eggs or embryos destroyed or stored.

How Does Natural Cycle IVF For Me?

The treatment is the same as conventional IVF, but without the fertility drugs that are used to stop natural egg production and hormones that boost the supply of eggs.

As your ovaries are’nt being artificially stimulated, you don’t need to rest as you would after conventional IVF.

If your treatment is unsuccessful, you can try again sooner if you wish.

Infertility - Treatments Available For Men & Women!

Dr. Ashwini Talpe 95% (3268 ratings)
MBBS, MS - Obstetrics & Gynecology, Fellowship in Infertility (IVF Specialist)
Gynaecologist, Aurangabad
Infertility - Treatments Available For Men & Women!

Infertility is a condition which is characterized by the inability to have a baby for over a year in spite of having planned and unprotected sex. It is a pretty common phenomenon for both men and women. However, there are several treatments available for both the sexes to help them recover from this problem. Here are some of the most common treatments available for infertility:

For Men

1. Changing your lifestyle: Certain factors in your lifestyle, which may cause you to be infertile include the medications you take, lack of exercise or not having intercourse frequently enough or not at the right times. The solution for these problems is simply incorporating certain changes in your daily life such as exercising more, sticking to a healthy diet or having intercourse more often at the right times.

2. Sperm retrieval: Sperm retrieval is the technique used when you cannot ejaculate or when there is hardly any sperm present in your semen. It is also used in case of a low sperm count.

For Women

1. Intrauterine insemination: Intrauterine insemination is a process in which healthy sperm cells are put into the uterus so that the egg gets fertilized when it is released. The sperm cells have to be inserted at the time when your ovaries release eggs; therefore it is crucial to know your menstrual cycle as well as how fertility drugs are affecting it.

2. Fertility drugs: Fertility drugs are used to stimulate ovulation. This is done by administering medications which either regulate or cause ovulation to occur. There are several types of fertility drugs, so you should talk to your doctor about which should be the best for you.

3. Hysteroscopic surgery: This is a last resort, which is taken only when there are significant problems such as intrauterine scar tissue, uterine septum or endometrial polyps.

4. IVF: IVF is an assisted reproductive technology. During IVF, the sperm is at first retrieved, after which fertility medications are given to the woman so that the egg can be retrieved. Finally, the egg is fertilized on a laboratory dish and injected back into the mother or a surrogate mother.

In case you have a concern or query you can always consult an expert & get answers to your questions!

5 people found this helpful

Tubal Reversal vs IVF : Pregnancy Success Comparision

Dr. Kinker. Mrinal 85% (10 ratings)
MBBS, MS - General Surgery
General Surgeon, Kota
Tubal Reversal vs IVF : Pregnancy Success Comparision

In vitro fertilization (IVF) includes empowering the woman with medicines, taking various eggs from her ovaries, fertilizing them with her partner’s sperm, and inserting a portion of the subsequent embryos into her uterus with the trust that one will form into a fetus. 

Tubal ligation reversal, on the other hand, requires a laparotomy, which needs a much bigger entry point on the abdomen, usually around four to six fingers long. Since the skin, each of the muscles, and different tissues of the stomach must be sliced through, there is extensively more uneasiness and a longer recovery time required after the surgery, when compared with a laparoscopic surgery, for example, with a tubal ligation. 

Here are a few common differences: 

  1. Sperm quality: The male partner needs a sperm test before basic procedures of either of the two. In case that the sperm quality is great, then the couple could consider proceeding. In case that the sperm quality is poor, in vitro treatment is the better alternative. With IVF, poor sperm quality is effectively overcome. 
  2. Tubal status: The length of the remaining tubal stumps after tubal ligation is an important aspect. The more extended the two remaining stumps are on each side, the better and more effective is the pregnancy. The shorter the stumps, the lower are the odds for pregnancy. 
  3. Status of other pelvic conditions: Pelvic endometriosis or any scar tissue in the range of the tubes or ovaries would diminish the chance for accomplishment after tubal ligation reversal. Although, IVF pregnancy achievement rates are usually not influenced by these conditions. Along these lines, in vitro fertilization is most likely a superior alternative in women with noteworthy endometriosis or pelvic scar tissue. 
  4. Female age: Chances for pregnancy with either tubal ligation or IVF decrease in the mid to late thirties and significantly reduce at the age of thirty-eight. By age forty-three or forty-four, not many women will have the capacity to have a baby using either approach. 
  5. Egg amount and quality: A few women have a decrease in either egg amount or quality prior in life than anticipated. In this manner, the woman’s ovarian capacity needs to be tested before a choice is made in regards to whether to continue with either tubal ligation or in-vitro fertilization. AMH levels, ovarian antral follicle number, and day 3 FSH levels are generally done to evaluate ovarian capacity or hold. 
  6. Doctor intervention: The greatest favorable position of tubal ligation reversal over IVF is that once the woman has experienced the surgery she ideally will not require any medication through the doctor, for example, medications or systems, keeping in mind the end goal to get pregnant.

In case you have a concern or query you can always consult an expert & get answers to your questions!

316 people found this helpful

IVF - What Do You Think You Know About It?

Dr. Nalini Gupta 88% (225 ratings)
M.Sc, MD, MBBS
IVF Specialist, Delhi
IVF - What Do You Think You Know About It?

IVF or In Vitro Fertilization is a procedure carried out in a laboratory where a female egg is fertilized manually with male sperm. After this, the embryo is introduced into the uterus. IVF is of great help to those couples who face fertility problems due to varied reasons. With each passing day, the success rate is increasing steadily. But, before seeking such assistance, you need to know and consider various factors.

Here is a list of few facts that you must know before opting for IVF.

What is IVF?
The very first thing you must know is that if you ever became pregnant in natural manners, then the chances of getting a positive result with IVF increases in your case. This is such a procedure which is beneficial to people with nearly all kinds of infertility complications. If you have such an infertility condition where fertility medications also proved to be unsuccessful, then you may choose IVF in that situation.

Eggs are first taken out from the ovary of a would-be mother and then fertilized outside before replacing it inside her womb. The treatment procedure is a bit lengthy. Before the collection of the egg, the woman needs to take prescribed medications and visit the clinic for check- ups or scans for a couple of weeks. The procedure of egg collection takes nearly an hour and after that, the patient must return to the clinic for the transfer of embryo and also pregnancy blood test. In total, the treatment takes approximately four to five weeks. Various shorter treatment forms are also available as well as other essential things that you must know before opting for IVF.

Are there any risks?
Many patients seeking fertility treatment from IVF generally have a misconception that the risk of breast cancer, ovarian cancer, endometrial cancer increases if this procedure is tried. But, you need not worry at all as IVF has no link with the increased risk of such diseases.

In many cases, it is seen that a couple possesses extra healthy embryo other than one. In that case, if the couple feels like, then they can donate the extra embryo to others. In conditions of male infertility, donated sperms are also used. A woman whose age is more than 45 usually has very fewer chances of becoming pregnant with her own egg, she may take the help of donor eggs.

You need not feel ashamed of infertility as it is a common phenomenon. With a success rate of 40%, many couples seek this procedure to get conceived. Besides infertile people, single women and same-sex couples also opt for this procedure. It means one in fifty babies is seeing the light of the Earth using IVF.

In case you have a concern or query you can always consult an expert & get answers to your questions!

342 people found this helpful

How To Prepare Yourself For IVF?

Best Fertility Centre In India
IVF Specialist, Chennai
How To Prepare Yourself For IVF?

One of the major milestones in a woman’s life is the entry into motherhood. For most women, when this does not happen in the natural logical sequence of things, there is anxiety and lot of pressure from family and friends.

However, with advancements now, there are options like intrauterine insemination and in vitro fertilisation (IUI and IVF) available, which can help increase the chances of conception and pregnancy. IVF is where the egg is retrieved from the woman’s womb, fertilised externally and then transplanted back into the uterus where it grows to full term. However, there are always unanswered questions like how long to wait before going for IVF, is it the right procedure for me, etc.

Read on to know to find answers to some of these.

  1. Maternal age: As a woman reaches 35 and a man reaches 40, the fertility rates drop significantly. The chances that a woman at 35 will conceive is about 20%, which goes down to 5% if the woman is 40. However, this rate can be significantly increased by using IVF. The quality of the egg would gradually deteriorate, and so if a woman is nearing 40, it is better to consider IVF as the ovarian reserve would be optimal with IVF.
  2. Failed intrauterine insemination: In couples who have problems with the sperm reaching the uterus, intrauterine insemination (IUI) is first attempted. However, if 3 or more attempts of fail, it is time to consider IVF.
  3. Duration of inability to conceive: While some couples conceive quite promptly in a month or two, most take about 6 to 8 months of unprotected sex to conceive. Therefore, IVF can be an option if you are failing to conceive even after a year. Less than a year, don’t fret. Take it easy and it might just do the trick.
  4. Medical health: Both the partner’s medical health should be taken into account. Lifestyle changes like smoking, alcohol abuse, drug abuse should be considered, which can account for poor sexual performance and therefore lead to an inability to conceive. Health conditions like diabetes and heart disease can also lead to infertility. Hypothyroidism in women is another thing that must be ruled out, as it often leads to an inability to conceive.
  5. Sexual problems with the partner: One of the first things to do before going for IVF is to check that the male does not have any issues. Be it erection issues or ejaculation issues or sperm issues, they need to be ruled out. Sperm quality, quantity, and motility have to be analysed, and if they are optimal, IVF can be considered.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3417 people found this helpful

Does IVF Results In Twins?

Bourn Hall Fertility Centre 87% (10 ratings)
Multispecilaity IVF Clinic
IVF Specialist, Gurgaon
Does IVF Results In Twins?

In-vitro fertilisation (IVF) is one of the popular Assisted Reproductive Technologies (ART) for treating infertility and helping couples to conceive. The process involves the fertilisation of the egg with the sperm in a laboratory and thereafter, inserting the embryo formed, into the uterus. But lack of understanding about the topic has given rise to a number of myths such as:

Myth 1: IVF increases your fertility levels

Instead of making you more fertile, IVF stops your natural fertility cycle. This is usually done through hormones that are taken at the beginning of the process. The aim of such an action is to essentially put an end to your natural fertility process and create in its place an artificial cycle.

Myth 2: IVF hormone injections make you prone to uncontrollable emotions

In actuality, IVF hormone injections don’t cause you to suffer from out of control emotions but make you happier. This is because they come packed with the female hormone oestrogen, which produce endorphins (brain chemicals) that give you a sense of wellbeing.  The wave of emotions that you end up experiencing is a result of the stress and anxiety surrounding the success of a cycle.  

Myth 3: IVF never fails but is always successful

The success of the procedure depends on a number of factors such as quality and quantity of embryos and age. It is said that chances of conception decreases with age, with women above 40 reporting reduced fertility potential as well as success rate. On the other hand, women below the age of 35 have about 41% chance of getting pregnant.

Myth 4: It causes you to have triplets or twins

No, it’s not necessary for multiple births to take place if you opt for IVF. You can reduce the prospect of having twins or triplets by cutting down on the number of embryos that get inserted into the uterus.

In case you have a concern or query you can always consult an expert & get answers to your questions!

3588 people found this helpful