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Overview

In Vitro Fertilization: Cost, Procedure, Recovery, Risk & Complication

What is IVF?

In-Vitro Fertilization (IVF) consists of a series of procedures that are used for the treatment of genetic or fertility problems, while assisting the conception of a child. One of the most effective forms of assisted reproductive technology, IVF procedures can be conducted using a woman’s own eggs and her partner’s sperm. It can also be done by taking the eggs, sperm or embryos from a known or unknown donor. There are some cases where a gestational carrier (a woman with an embryo implanted in the uterus) can be used.

During IVF, mature eggs are retrieved from a woman’s ovaries and fertilized with the sperms in the lab. Once it has been fertilised, the egg or eggs are implanted back in the uterus. A cycle of IVF can take about 2 weeks.

Indication

One may have to undergo an IVF treatment in the following conditions:

  • If a woman’s fallopian tubes are blocked or damaged
  • If ovulation is infrequent/absent, or there are few eggs available for fertilization
  • Loss of normal functions of the ovary before reaching the age of 40
  • A previous treatment of tubal ligation, where the fallopian pipes have been cut/blocked permanently. In this case, one can opt for IVF instead of tubal ligation reversal.
  • Poor mobility, abnormality in sperm size/shape, or below average concentration of sperm of the male partner
  • If you have the conditions of endometriosis (uterine tissue will implant and grow outside the uterus) or uterine fibroids
  • Unexplained fertility or a genetic disorder

What Procedure is followed :

Pre Procedure

Before beginning the process of IVF, both the partners may have to go through certain pre-procedure screenings such as:

  • Ovarian reserve testing, for determining the quality and the quantity of the eggs. The concentration of estrogen, follicle stimulating hormone as well as the antimullerian hormone in your blood is checked by your doctor in the initial days of the menstrual cycle. These test results may help in predicting the response of your ovaries to fertility medications.
  • Analysis of the semen of the male partner
  • Screening for any infectious disease like HIV
  • A mock transfer of the embryo for determining the depth of the uterine cavity and the technique that may work best for you
  • An examination of the uterine cavity that may involve sonohysterography (fluid is injected in the uterus through the cervix and an ultrasound creates images of the uterine cavity) or hysteroscopy
  • Some serious question like the numbers of embryos that will be transferred, what needs to be done with the extra embryos, how to handle a multiple pregnancy, and the complications that may occur with donor eggs and sperms or a gestational carrier have to be discussed.

During Procedure

IVF treatment involves the following steps:

  • Ovulation induction, where synthetic hormones stimulate the ovaries for producing multiple eggs. You have to be under several medications for a week or two before the eggs are ready for retrieval. Vaginal ultrasound or blood tests are examined by the doctor to determine it.
  • Egg retrieval, through a transvaginal ultrasound. In this process, an ultrasound probe is inserted in the vagina for the identification of follicles. A thin needle is guided through the ultrasound guide to reach the vagina for collecting the eggs. The laparoscopy method can also be used for the same.
  • Sperm retrieval through masturbation or testicular aspiration in case the partner’s sperm is being used
  • The next step is fertilization either by insemination (sperm and eggs are incubated overnight) or Intracytoplasmic sperm injection (ICSI), where a single sperm is injected directly in a mature egg.
  • Embryo transfer is next step performed at the doctor’s clinic. It takes place two to six days after the retrieval of the eggs.

Post Procedure

Once the embryo has been transferred, you can go back to your regular schedule. However, your ovaries may be enlarged for a few days, so it is advisable to avoid any vigorous activity that may cause discomfort.

The side effects of post treatment may involve:

  • Passing of a small amount of clear/bloody fluid after the procedure, which is caused because the cervix is swabbed before the transfer of the embryo
  • Mild bloating and cramping
  • Constipation
  • Breast tenderness because of the high levels of estrogen

In case you have a moderate or severe pain after the transferring of the embryo, consult your doctor who will evaluate your condition. Any indication of a complication like an infection pr ovarian torsion can be examined and treated.

Risk & Complication

An IVF procedure may bring along with it certain risks and complications like:

  • Multiple births if more than one embryo has been implanted in the uterus. Multiple foetuses can often lead to premature delivery or a low birth weight of the newborn.
  • The frequent injection of fertility drugs to induce ovulation may lead to ovarian hyperstimulation syndrome, a condition where the ovaries become painful and swollen.
  • Using an aspirating needle for collecting eggs may lead to bleeding, damage or infection in the bowel, bladder or a blood vessel.
  • In some cases, there may be chances of an ectopic pregnancy. This is a condition where the fertilised egg will implant outside your uterus, generally in the fallopian tube. The egg would not be able to survive outside the uterus and the pregnancy will not be possible to be continued.
  • Miscarriage or birth defects
  • There may be a possible connection between some medications used in IVF and a specific type of ovarian tumor, though there have not been enough cases to support it.
  • The procedure of IVF can be physically, emotionally as well as financially draining, leading to stress.

More Info

Make sure that you continue having the medications after the embryo transfer has been successfully completed. It is better to avoid travelling during this period. It is generally after 2 weeks after the embryo transfer that you have to go for a pregnancy test. It is important not to be stressed during this phase, but be optimistic and occupied. Also, the pregnancy test must be conducted by a doctor at the clinic and not by yourself at home.

The cost of an IVF treatment may vary from Rs. 10,000 – Rs. 70,000, depending on your condition.

Popular Health Tips

5 Step IVF Procedure!

DNB (Obstetrics and Gynecology), MBBS
IVF Specialist, Delhi
5 Step IVF Procedure!

In Vitro Fertilization is the most common and effective way to help women to conceive. This method is a blessing for those couples who are not able to have children because of some medical issues. IVF has opened the doors of hope of such couples. IVF method is an artificial method of fertilizing egg outside the body in the laboratory and then implanting it in the uterus. This method is best when the other treatments have failed. The success rate of IVF is high and the chances of multiple birth is more. This method of conceiving is getting popular in many countries among childless couples. Studies have shown that one percent of the babies in United States are born through IVF. IVF is safe and economical. This method keeps on of the parent biologically connected to the child.

Procedure:

  1. Curbing the natural menstrual cycle: The women before undergoing this process is given injection for two to three weeks to supress her natural menstrual cycle.
  2. Super ovulation: To increase the production of eggs, fertility drugs containing the fertility hormone follicle stimulating hormone- FSH are given to the woman. This makes the ovaries to produce more eggs than usual. Regular ultrasound is done to examine the process of ovaries.
  3. Retrieving the eggs: The produced eggs are then collected through a minor surgical procedure known as follicular aspiration. In this surgery, a very thin needle is inserted into the ovary through vagina which is connected to a suction device. This device sucks the eggs out. This process is repeated for each ovary. Doctors try to collect 15 eggs in one cycle which can give high chances of successful pregnancy. These eggs can be frozen or donated too.
  4. Insemination and fertilizationThe collected eggs are then placed with sperms in a controlled environment chamber. Sperms enter the egg naturally and sometimes it is directly injected, called intracytoplasmic sperm injection. After this the fertilized egg is divided and becomes an embryo. After this doctors recommend to diagnose the embryo in order to check if it is healthy and not diagnosed with some genetic disease. This decision is totally on the parents though. The selected embryo is then transferred. Women is given progesterone, this help the lining of the womb to receive the embryo.
  5. Embryo TransferGenerally, more than one embryo is placed in the womb. This is done on the mutual discussion of the doctors and the parents. The embryo is transfer with a thin tube or catheter. It enters the womb through vagina. Once the embryo is attached to the lining of the womb, the embryo starts growing and the rest development is parent’s responsibility by taking good care of the mother.

Artificial implantation techniques may differ clinic to clinic but the ultimate goal is to bring a baby in this world. IVF has become the best way for conception for the ladies who are not able to conceive and the birth success rate has made it more popular. 

2058 people found this helpful

IVF Process - Know More About It!

MBBS Bachelor of Medicine and Bachelor of Surgery, DNB - Obstetrics & Gynecology, DGO
IVF Specialist, Delhi
IVF Process - Know More About It!

With infertility now impacting many patients, they are now choosing to engage in different ways of conception, such as Assisted Reproductive Technology such as in vitro fertilization (IVF). However, IVF treatment can be actually psychologically and economically challenging for most people, therefore, before you opt for this choice, it’s essential that patients must know about this process in detail.

Research the process
Before patients go for IVF treatment, they should understand the treatment pattern and stages of treatment and also what is involved in each phase. Being well advised is the best way to be psychologically prepared for the psychological and physiological changes that IVF can bring.

Make sure that you’re as healthy as possible
Adopting a healthy diet and fitness program is the best way to start any fertility journey. Studies have shown that women who are in better physical and emotional health have the maximum chance of success with IVF.

What causes should be considered while going for IVF?
The problems such as Endometriosis where the endometrial lining of the uterus gets inflammation and does not allow the mother to conceive a baby, other conditions such as when there is a very low sperm count. Also, there are problems associated with the functioning of fallopian tubes or the uterus, the formation of antibodies in the mother’s blood which causes harm to egg or sperms, the sperm motility is low or when the complications related to fertility cannot be determined correctly.

Success rates are not designed to your exact conditions and so can give a deceiving picture about the chances of your success. It is also essential to look carefully at exactly what is being calculated. On average the success rate of IVF is around 35%, a significance that most people will have to endure a number of treatments before accomplishing a successful pregnancy.

4408 people found this helpful

Different Techniques That Can Be Used For Egg Freezing!

MD - Obstetrtics & Gynaecology, DGO
IVF Specialist, Mumbai
Different Techniques That Can Be Used For Egg Freezing!

Egg Freezing, which is also known as mature oocyte cryopreservation, refers to the method through which reproductive potential is restored among women. Eggs get harvested from the ovaries, frozen and in an unfertilized manner and are stored for purpose of using them later on. The egg freezing procedure is recommended for those women, who would like to delay conceiving baby due to various kinds of reasons.

Before the freezing of eggs, it is important to first retrieve the eggs. Let us look at how the eggs are retrieved, followed by the procedure of egg freezing through two different ways.

Retrieval of Egg

Egg Retrieval takes place just like it is done in case of in vitro fertilization (IVF). Women would need to be put under medication for hormones or through injections, which shall lead to the stimulation of ovaries, leading to more eggs getting matured. After this women would receive the necessary medication to stimulate ovulation and then the extraction of eggs takes place through the use of a needle. Specialists perform this whole procedure by putting women under the effect of anesthesia and are also guided by ultrasounds. Once the extraction is completed, the freezing takes place.

There are two different techniques involved in the egg freezing process. They include:

Slow Egg Freezing Method

A substance called cryoprotectant is used in order to protect the biological tissues from getting damaged out of freezing. This slow freezing method of getting eggs freezed relies on low initial concentrations of crytoprotectant. The cryoprotectant in low concentration is introduced when the egg is at a relatively warm temperature and still continues to experience the usual functions of a living cell. Then the cryptoprotectant would spread all throughtout thus fill the egg, hence replacing most of the water inside the egg. The egg is then inserted into a small container made of plastic and ultimately get placed inside a cooling chamber. The lowering of temperature, to around -6 degree centigrade, takes place through injecting very tiny amounts of liquid nitrogen into the cooling chamber. The cooling process is controlled by a computer.

The main purpose of these techniques is to avoid ice crystals from getting formed in the egg. During the spreading of the cryoprotectant, if the ice crystals are still present, they can cause damage to the egg and hence the egg may not survive the process of thawing. Then the temperature is lowered further to around -32 degree centigrade. By this time, the egg’s metabolic rate become slow. The container where the egg was placed, is then dipped inside the liquid nitrogen, forming a solid.

Rapid Egg Freezing Method or Vitrification

At the time of rapid freezing method, there is high concentration of initial cryoprotectant whereas the cell remains at room temperature. The egg is unable to stay for long in this temperature and thus gets poured immediately onto the liquid nitrogen. Cryoprotectant spreads at a rapid rate so as to avoid ice-crystal from getting damaged. Vitrification is a very new method for freeing eggs. Recent research has shown that vitrification of eggs largely improves the possibility for survival after thawing and the rates of pregnancy.

2951 people found this helpful

Embryo Freezing And Cryo Preservation - Know More About It!

MD - Obstetrtics & Gynaecology, DGO
IVF Specialist, Mumbai
Embryo Freezing And Cryo Preservation - Know More About It!

Cryopreservation is usually performed as a component of in vitro fertilization, which also tends to include ovarian hyperstimulation, retrieval of egg and embryo transfer. With the frozen embryos available, a woman need not undergo stimulation through fertility drugs for having an embryo transfer during a cycle of an infertility treatment. When sperm gets collected during microsurgery or through other means and being frozen for a subsequent cycle of IVF, additional surgery might well be avoided.

Embryo Cryopreservation

At the time of standard manner of treatment for infertility, hormones get used to stimulate the development of multiple eggs. Then, after those eggs are retrieved and fertilized in the laboratory, more embryos might be created than those, which could be transferred quite reasonably to the uterus of a woman. Now, when such extra embryos are of sufficiently good quality, they might get cryopreserved or in simple language, frozen, so that they could get transferred at some future date. Approximately in 25% of IVF cycles, embryo cryopreservation becomes possible, which in turn provides the opportunity to have an extra embryo transferred, without going through the inconvenience and bearing the expense of a full cycle of IVF.

Embryos may get frozen on Day 2 / Day 3 / Day 5 stage. We can freeze the embryos at the age of 40yrs also. One thing should be noted that not all embryos are right candidates for cryopreservation. Unfortunate thing is that some embryos could well get damaged by cryopreservation and certain experiences have even show that high quality embryos are more likely to suvive and become capable of getting developed further after freezing, than other types of embryos. Embryos, which divide slowly or are somehow irregular in other ways, do not perform well after cryopreservation, hence do not get frozen. These problems generally tend to arise among older women, so cryopreservation is normally not a recommended option for patients around the age 40 and older.

Once the embryos are placed in a cryoprotectant solution, they are made to freeze in a computer-controlled device, which is specifically designed for embryo cryopreservation. Embryo storage for a long-term basis takes place in liquid nitrogen at a temperature of -320 degree Fahrenheit.

Embryos that are cryopressed, get replaced either during a natural menstrual cycle or in case of a hormonally controlled cycle. Reasonable amount of care is taken to minimize the possibility of damage caused as a result of cryopreservation. Now, depending upon the stage of embryo during the time of freezing, around 60 and 90% survive this process of freezing. The rate of pregnancy after those embryos get transferred is quite similar to that of those, when embryos are fresh.

Extended amount of storage in liquid nitrogen does not have any effect on an apparent basis on their viability. The embryos which get frozen after numerous years of cryostorage perform equally well as those which are frozen for only a couple of months.

Since the year of 1983, the procedure of cryopreservation has lead to the birth of thousands of babies on a worldwide basis. Though this has been used on an extensive basis, yet there have not been any report of any kinds of increase in birth defects due to cryopreservation.

3163 people found this helpful

IVF - A Complete Guide For Men!

MD - Obstetrtics & Gynaecology
IVF Specialist, Sonipat
IVF - A Complete Guide For Men!

Have you and your partner decided to complete your family by having a baby? Are you unable to conceive even after trying really hard? You are not alone. There are many couples who are facing this problem. But there is nothing to worry about at all. Latest and advanced science is offering solutions for this problem. When none of them are working for you, you should try In Vitro Fertilization or IVF. During IVF treatment, men have as vital a role to play as women. A man needs to really support and care for his partner during this period.

Here is a guide for men for IVF treatment:

  1. Keep a check on your weight: If you are overweight, then your sperm will be affected. Also, some studies have shown that the mobility of the sperm is affected by obesity. It will also affect the sperm count when your BMI value is too high. So, it is always good to maintain the BMI levels required, based on your height, age and gender.
  2. Temperature of the sperm: If you are a cyclist or use a laptop for extended time periods by keeping it on your lap, then the production of sperm could be affected because it is going to increase the temperature of the testicles. Make sure that you take care of this.
  3. Make changes to your lifestyle: If you smoke or drink, then you will have to make sure that you cut down or stop because this is going to affect not just the quality of the sperm but also the quantity of the sperm. Smoking decreases the mobility of the sperm.
  4. Healthy dietA healthy diet means healthy sperm quality and quantity. So, you should always keep a check on what you are eating. You will have high fertility levels if you consume green vegetables, fresh fruits and pulses as part of your daily diet. You should cut down on processed food and make sure that you are eating fresh and healthy food.
  5. Regular Exercise: You will have to maintain good health and for that, you need regular exercise. You do not need to join the gym and lift weights. You can do a few exercises at home. Exercising can also help to get rid of anxiety and stress and help you to stay healthy.

Get advice from experts as they can help you with tips to follow during the IVF treatment or when you are preparing yourself for the IVF treatment. You and your partner can do these things together and achieve better results.

3630 people found this helpful

Popular Questions & Answers

My cousin had undergone ectopic surgery twice and her two tubes has been removed. She is now 43 and after first ectopic she gave birth to boy who is now 10 years. Is it possible and safe if she for second child at this age thru IUI or ivi.

MS - Obstetrics and Gynaecology
Gynaecologist, Delhi
If both her tubes are removed she has to go for IVF. With age the quality and quantity of eggs decrease and chances of conception are less. Chances of congenital anomalies in baby also increases if maternal age is >40 yrs. If she wants a second child she can go for donor eggs and IVF conception.
1 person found this helpful

Hi, I am 31 yrs. After ivf failure developed two small fibroid 12 mm ant & post wall of my uterus. Any homeopathic treatment. Please give me guideline.

MBBS, DNB - Obs & Gynae, Diploma In Reproductive Medicine (Germany), Fellowship In Laparoscopy, Fellowship in Reproductive Medicine & ART, Hysteroscopy advanced traraining training
IVF Specialist, Delhi
Ivf is not related to development of fibroid and it could be a possibility that it was missed at that time. Although the size is very small but you need to get it evaluated for its location that might cause problem in conception or ivf .yes medical treatment is possible provided it is indicated.

One of our friend had IVF treatment with their own egg and sperms. The couples blood groups are O+ but their child blood group is B+. Please let me know O+ parents can have B+ child.

MD - Obstetrtics & Gynaecology, FCPS, DGO, Diploma of the Faculty of Family Planning (DFFP)
Gynaecologist, Mumbai
Somewhere something is misunderstood. Theoritically sperm O pos and egg O pos can not give rise to B pos child. Recheck all blood groups is first step.

HI, A lot of information is given in precautions to be taken in 1 st trimester. Would like to know expertise opinion on what precautions and restrictions should be taken during early pregnancy. I am 6 weeks pregnant post IVF conception with DCDA twins.

Mbbs, MS(obstetrics and gynecology), Fellowship in laproscopic gynecological surgery
Gynaecologist, Delhi
You have precious pregnany. Avoid bumpy travel, prolonged standing, intercourse, avoid eating fruit like papaya, pineapple. Drink plenty of fluids, take healthy deit, all medicine regularly.

Table of Content

What is IVF?

Indication

What Procedure is followed :

Risk & Complication

More Info

Play video
IVF Improvement Success Rate
Hi,

Mera naam Dr. K S Anamika hai. Ek stri rog aevam infertility vishagya hu. Aaj apse baat krungi ki aap apne IVF k success rate ko kaise improve kar skte hain. Aaj samaj mei hamare paas infertility ke cases bahut badh gye hain. Magar samajik kuntha jo sath e thi vo jarur kam ho gyi hai. Mariz hmare pas bilkul freely aate hain. Or IVF ke lia puchte hain or IVF krate hain. But bhartiye dumpatti ke pas abhi bhi itna financial support nhi hai ki vo do bar, teen bar, IVF kra sakein. Kyuki IVF ka success rate 40-45% tak hi hota hai, to hmesha marizon ke mann me ek khayal hota hai ki aisa vo kya kren ki unke IVF ke results ache aayen. To mai isi sambandh me aapki madad krna chahungi.

IVF ka jo taknik hai usmei pehle ande bnaye jate hain. Fir ande or pati ke sperm ka fertilization bahar kr ke, apke bache dani mei embryo ko transfer krte hain. Uss embryo ke transfer ke din se leke 15 din ke baad apko apna pregnancy test lena hota hai. Aur iss 15 din ke dauran marizon ke maan me kayi baatein chalti rehti hain. Mai aisa kya karun ki mere IVF ka result acha ho? Is chiz ko hum 2 bhago me baatenge. Pehle to IVF ke pehle kuch steps or dusra apke embryo transfer ke bad ke 14 din mei aapki savdhaniyan. Pehle apko khayal rkhna hai ki aap sahi samay pe apna IVF krayein. Jaise ki kayi bar mariz 10 saal, 15 saal, shaadi ke baad bhi chizon ko talte rehte hain.

Jis se unki umar badhne ke baad success hone ke chances kam ho jate hain. To IVF ka chunav aap jaldi kar lein. Aap apne sharir ki har chiz pe dhayan dein. Vitamin deficiency, anemia ko pehle treat kar lein. Aur teesra apne pelvic organs ke aas paas jo bhi problem ho unko thik kara lein. Aapke andedani mei endometriosis ya kuch or bimariyan hain, inko pehle settle down karen. Ab baat aati hai ki apne IVF kara liya aur baad ke 14 dino tak apko kya savdhaniyan leni hai. Kayi baar mariz aur unke parivaar jan ye kehte hain, ki hum to inko bistar se uthne nhi denge, ye bilkul leti hi rhegi 14 dino tak, taki we can get the results. Lekin aisa krne se aapka mansik tanav aur badhta hai. Studies batati hai ki aap apna dincharya jaisa tha, vaise rakh sakte hain. Bss apko physical stress nhi lena hai. Dusra religiously aapko medicines follow karni hai. Aisa karne se aapka hormonal imbalance nhi hoga.

Bleeding ke chances kam honge. Or success results hume ache milenge. Infection se apna bachav krna hai. Bahar ka khana, bahar ka toilet use krna, peshab bahut der tak rokna, in sab chizon par pura dhyan dein. Agar aapke peshab mei thodi bhi jalan ho to use thik kra lein. Kyuki urinary infection bhut bada cause hai ki apka embryo apni jagha pe transfer nhi ho pata hai. Aur inhi sare nirdeshon ke sath me aap sab ko shubh kamnayein dungi, ki apko bhi happy family mile. Jitne bhi infertile couples hain, vo aaj ke vigyan ke tarikon ko use kr ke jld se jld mata pita banne ka sukh prapt kren.

Thank you!
Play video
Egg Freezing - Biological Clock No Longer Exists!
Dr. Nandita Palshetkar aspires to help couples achieve their dream of parenthood. She highlights the struggles of women as their lives are constantly controlled by the continuous ticking of the biological clock and reveal that egg freezing is the solution for the existence of ordeals revolving around this clock. Egg freezing is just not an instrument for a safe and healthy motherhood, but also a new-age totem to the freedom of women about their own body and life.

Dr. Palshetkar is one of the pioneers in the IVF clinics of India and has been instrumental in helping over 25000 such couples to achieve parenthood. Her major contributions include the record of being the one to establish the first laser hatched twins in India; and also the distinction of having achieved pregnancy in a 60-year-old woman.

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A few years ago a beautiful girl fall in love, she was 40 when she was married. And you know as it s a dream of every married couple she wanted and waited for a child. Unfortunately, heartbroken. This phase can be a devastating phase in a woman's life. Especially it not only effects the health but also the mental and emotional health of a couple. By the way the women I m talking about is former Miss World, Diana Hayden. In 2016, Diana delivered this beautiful baby girl, Arya. Diana s baby girl Arya was from an egg which is preserved for 8 years, when Diana was 34. So How did this happen? I think before going to all the technicalities of vitrification and what it is let me explain to you the biological clock of women. When the child is actually in the womb of the mother you know how many eggs are there? 5-6 million eggs. And when she gets born those eggs become just 1 million, so many eggs were died. At puberty its about 2-5 lac eggs. And mind you at 37 they become just 25 thousands eggs. And when she turns 50 it s only a thousand eggs. See this is important to grasp because as the women ages it becomes difficult for her to conceive. You know nearly 70% of the people at the age of 40 find difficulty to conceive. Another problem associated with age is also Down syndrome. And this can be prevented today. When the girl is 30 years old she has a chance of having a Down syndrome baby may be in 1 in thousand. But when she turns 40 the chance increases to one in hundred. Then there are other diseases which effect the ovarian reserve which help and prevents and these problems which I m talking about can be helped by technology. You know like endometriosis, we have endometriosis as a disease which attacks the ovaries the abdominal cavity everywhere. And what it does is reduced the fertility rates, makes it difficult for the patient to get pregnant. Then the other conditions are benign you know cyst adenomas any kind of tumors in the ovary. Multiple surgeries sometimes you know because of the cyst doctors have to do multiple surgeries in the ovary, those are the conditions which are potentially harm the ovary. Another condition that we must remember all of us is cancer. Today in India there is no life after cancer. When cancer is diagnosed people are in shocked, they depressed, and they don t think that they will be a cancer survival. But I want to put this message today that today cancers are curable. There are a lot of cancers which people fight and lived to tell the tale and I have so many patients who come to me and say that we want a baby, they have just had chemotherapy, radiotherapy. Now the problem with the patients is this that the chemotherapy and the radiotherapy damages the ovaries. So, in these cases what do you do? All these cases you must remember has a solution. But before I go to that can I have an audience some volunteers whose 20 to 21 years old and who would like to just volunteer. Hi ma am. What s your name? And could you introduce yourself? So my name is Samiksha and I m 21 and I m currently studying biotechnology. Okay. 21 wow! What an age! I love to be that. What is your future plans? I wish to do my post graduation and then maybe MBA. I think today s generation all wants to do post graduations and MBA is a must. Absolutely. So, then when u planned to get married and have babies. What is the thought process in your mind? Get married at the age of 28 may be and babies after 32. Wow! Okay, so I think today's women all have a kind of a similar plan in their mind. You know they study, want to become independent, it s so very important. So let s put Samiksha and take her into two scenarios. one scenario is Samiksha got married, I mean first she gets her degree, gets the fabulous job, people waiting for her, you know young with innovative ideas, they want her, the company wants her and then she finds the man of her dreams. She gets married and after a couple of years they decide to start a family. So samiksha takes her back from her work, she has a baby a couple of years have definitely lost because child bearing then she decides that she wants to have another baby. So in this manner about 5 to 10 years of her life are spend in motherhood. Let s take the other scenario, samiksha is working and she has decided, she has meet the guy and they both decided that careers are important. She is ambitious, she wants to become the youngest CEO of the company. So she works she gets promotions. You know spends the whole midnight oil working and she becomes the youngest CEO at 40. And then she said okay I have achieved what I want to do and now I have time, I have the money, let me have a baby because she realizes that is the void in her life. And what happens to her, frustration because as I have said before 70% of the people who are the girls who are at the age of 40 face infertility and she is terrified of having a down s baby . So, what is the solution to all this? What have they lost? One of them have lost her productive years, her budding career, her promotions, travel opportunities and may be a little bit of love and romance and all the humdrum of life. And some women gains some few kilos also. And what is the other girl lost that she wants motherhood that s desperately. You know its important being of being a woman .and I think its really important that we get hold of both the aspects because today we are woman who want to do something. We have a fire in our belly. So, what is the solution? Technology is offering a solution i.e. egg freezing. I think it s a fantastic technology and today it is a reality. Imagine I love an ice-cream so I put it away in the fridge in freezer and two months later when I want to feel like eating that particular flavor I opened my fridge and take out that ice cream to satisfy my midnight hunger pangs. Similarly you can stash away your eggs in cold storage and have a baby whenever you want. That much freedom has been given to women by egg freezing. It s very radical I know very very radical. But what is this technology? This technology is Vitrification. You can see the video on the screen and you know what we do over here the egg is at the body temperature of 37 degree centigrade, we take it on this little straw and we dip it into liquid nitrogen which takes it to minus 196 degree centigrade rapidly. How rapid is the drop in temperature? Minus 20 thousand degrees per minute and that change in technology has resulted in those egg surviving. It s so rapid that there is no ice crystals and today with this technology the survival of the eggs is 97% to 99% and that s why this technology can be used. So if you look at those patients with low ovarian reserve because of endometriosis because of cancer, chemotherapy drugs radiotherapy is toxic to the ovary. So all these girls before undergoing therapy can freeze their eggs. The next question you asked is like you know is it very expensive? But let s take any middle income family. Don t you invest 1lac rupees in a car today, the car is a necessity of your life. Right! So then why not invest in this project. It s your fertility insurance. It s the insurance for having safe future generations. I think it may sound very ambitious and very far fudge to everyone all. But awareness is what is important and if we spread this awareness it will become more popular and more and more people will go for it and when there are more people giving this service I think the technology will become affordable. Do you remember how expensive the smart phones were? When it came? Today they are available for pit ants. I think the same is the thing about any technology. The more it becomes popular definitely it become more affordable. Reproduction is the virtue of persistent of life. And we must use our capabilities like egg freezing to aid this virtue. You know yesterday I was at at the airport and this young woman came running to me and hug me. I looked at her, she said, doctor thank you so much, I was your patient who froze my eggs five years ago with you. And today I m boarding a flight to Chandigarh to marry the man of my choice. But in the meantime of five years what I did was I went abroad started a startup and sold it to millions. She is saying because she is having my eggs with you frozen I was not worried of finding the Mr. Right. And now I m going to Chandigarh and I m getting married and if I have problems I know I can come back to you and have a baby . You gave me freedom. I think all the woman, actually I m getting goose bumps, all the women should have this freedom, this independence to think about what they want in life. Because we are all multi-tasking. Times are changing now and definitely we need to change with it. Look at Diana Hayden today. She is happy, she has evolved and what has she become. You know something she may be probably the world s first woman to freeze eggs for social reasons as far as back in 2007. That time this was experimental and used for cancer patients. So she has become not only you know not only motivational speaker and she is talking about it and she really tells me that every time when we tell please get married you are getting old she said what I did was right and I found my person of my dreams at the age of 40. So friends what I have just like to say is it s not just about the natures demand but for humanity and for love.

I think this idea is worth spreading.
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In-Vitro Fertilisation (IVF)
Hello everyone.

I am Dr. Madhu Garg. I am working as consultant in Miracles IVF and Fertility Unit and today we will be discussing something about IVF. IVF is In-vitro Fertilization and in common language it is also known as a test tube baby. In IVF, what we do is we take out both the gametes the female gametes and the male gametes and they are fertilized outside the body and then the resulting embryo is placed inside the female uterus which results into pregnancy. So the first question arises is who all need IVF? Couples who usually need IVF have problem in conceiving of long standing that could be because of female factors or male factors. The male factors include a less count, when the sperms are not normal of morphology or their motility is less, or there is complete of sperms in ejaculate and in female factors when the female is having a high age which is more than 35 years and she is having less egg count and there are problems in the tube. The tubes are the structure which transport the eggs from the ovaries inside the uterus and then the eggs meet the sperms and result in fertilization. If there is some kind of blockage in the tube, the egg is not able to meet with the sperm and the pregnancy is not happening, so these couples they always require some king of assistance which is usually IVF. In IVF the process starts from your menstrual cycle. We do basic test involves the hormonal evaluation, ultrasound scan, the semen analysis and after going through all of your reports, we start you on hormonal injections. These usually start from day tow or day three of your periods and they are given regularly for the next nine to ten days on a daily basis. During these nine to ten days of hormonal injections we evaluate you after 4 to 5 days and then every alternate day to see how your body is responding to these injections and to titrate the dose of these injections, so during these nine to ten days your follicles grow and when the follicles are mature enough then on the last day we give you a trigger injection and after the trigger injection, 35 to 36 hours after this injection we schedule your ovum pickup. For this pickup you are admitted to the hospital for a daycare. That means you are not having a night stay in the hospital. The stay is only for two to four hours and you have to come fasting 5 to 6 hours and under general anesthesia, we do a transvaginal ultrasound guided pickup. So the needle is passed through vagina and there is no cut or mark in the abdomen. All the eggs and the ovaries are aspirated outside and then the embryologist examines all the fluid which is aspirated and he checks whether how many eggs are present, what is the quality of these eggs and then he takes the decision of performing IVF or ICSI (Intracytoplasmic Sperm Injection) with male sample. In IVF what is done the eggs are placed with healthy sperms and then a natural process of fertilization is allowed. But in patients where the semen factor is less and morphology is less, the motility is less even, even a high-grade, a higher version of IVF is required which is called ICSI. In ISCI, every egg is injected in one sperm in the cytoplasm and not all patients need ICSI that is the decision of embryologist after seeing the semen sample. So these embryos which are formed after fertilization. They are left in laboratory for 3 to 5 days and after their growth in the laboratory they are transferred back to the uterus of the female and that transfer is very simple procedure which doesn t require any hospital admission and not does it require any anesthesia. After getting the embryos transferred you need to get hormonal support for the next 15 to 16 days and then the pregnancy test is done. So IVF pregnancy is equally as good as an actual pregnancy. You don t need any extra care, neither any cesarean delivery is required nor no special care is required during the pregnancy also.

So this is the basic what IVF is, who all need IVF and that is done under the cycle so the procedure is different according to your requirement and what you need and what is the best produce so you have to consult the doctor then you have to decide. So thank you everyone.
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Know More About IVF
Who should go for IVF Treatment?
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Know More About IVF
Good evening, I am Dr Anju Yadav and I am working as a Fertility specialist at Bourn Hall Fertility, Gurgaon. So, today I am going to speak about common myths which are there among people about IVF.

Some of the common Myths about IVF-

The most common misconception is related to bed rest. Some people feel that prolonged bed rest will help increase the chance of getting pregnant. But scientifically it is not true and there is no evidence till date that bed rest help in increasing the chances of pregnancy. In fact, some studies have shown that if you do bed rest for a long time, it will re distribute the blood flow to your pelvic organs and it might decrease the chances of getting pregnant. Hence, it is always advisable to resume your routine physical activity. After embryo transfer, we medically always advise our patients to refrain from strenuous physical activities but it is actually recommended to resume your routine physical activities.
The second prevalent misconception about IVF is that if you go for IVF, IVF will lead to your early menopause. This is again not true. Females are born with the fixed number of eggs and that can vary from lakhs to millions and females do not produce new eggs. So, when the female start menstruating every month, few of these eggs start growing and one of them will grow mature and ovulate while rest of the eggs will die in this process. So, ultimately every month we are going to lose some eggs. It does not matter whether we are trying to get pregnant or we go for IUI, IVF but some of the eggs are going to be lost. It is not like IVF will deplete your eggs, in fact, IVF is very safe and effective procedure and there are no ill- lasting effects in your body.
Some patients think that IVF causes ovarian cancer. It is again a myth because first IVF baby was born in 1978 and till then researches are being done on this topic and there is no evidence found till now that it causes Ovarian cancer. So, there is no need to be afraid of myths. It is very safe and effective treatment.
If you want to know more about IVF procedure, you can contact me on Lybrate.

Thank you.
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