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Overview

Pheochromocytoma: Treatment, Procedure, Cost and Side Effects

What is the treatment?

Pheochromocytoma is also known as the tumor of the adrebal glands.

How is the treatment done?

The catecholamines, epinephrine, nonepinephrine and dopamine hormones which are produced by the adrenal gland induce adrenaline rush in human beings. These are the hormones that allow a person to combat a grave situation and the secretion of these hormones are followed by temporary high blood pressure, sweating, increased heart beat and dry mouth. However these fight or flight hormones are produced profusely (the action being detrimental to good health), when Pheochromocytoma or a tumor develops in the adrenal glands. The condition is followed by high blood pressure, lightheadedness, nausea and other such symptoms.

The treatment of adrenal tumors revolves around the elimination of these tumors via surgery. If the aforementioned symptoms persist then the doctor initially assesses whether the level of these hormones are high in the body and that is found out after a simple blood test or a urine test. Sometimes an imaging test can also be conducted to evaluate the disposition of the tumor in the adrenal gland.

If the tumor is found or the level of these hormones are found to be abnormally high then eliminating the tumor through surgery is the best possible measure. The surgery should be preceded by blood pressure control regime. Blood pressure needs to be controlled during the surgery as well.

Who is eligible for the treatment? (When is the treatment done?)

The treatment of Pheochromocytoma is preceded by proper diagnosis.

Either 24 hour urine collection (which involves the collection of urine over a period of 24 hours) or blood test is performed to assess the level of the catecholamines, epinephrine, nonepinephrine and dopamine hormones in the body. If these hormones exceed the normal level by two times then imaging tests are conducted to evaluate the condition of the tumor. It is detected by either an MRI scan or a CT scan. If these scans fail to show the tumor another test called a 131-I-MIBG scan can be done. This test encompasses the injection of a radioactive iodine molecule into the bloodstream. The component is centralized around the area of the tumor thereby making it visible.

Control of blood pressure is crucial before and after the surgery. Alpha blockers drugs are given surgery and to regulate the response of the body during anesthesia beta blockers drugs are also infused into the system. Pheochromocytoma rarely becomes malignant. But if it is found to be cancerous surgery is usually followed by radiation or chemotherapy.

Currently the use of Tyrosine Kinase Inhibitors drugs for the treatment of adrenal gland tumor, in some cases have proven to be a viable remedy. However, the complete legitimacy of the drugs is yet to be formalized.

Who is not eligible for the treatment?

Some of the symptoms of Pheochromocytoma include high blood pressure, palpitation, profuse sweating and headache. A person who is observing these symptoms all of a sudden should definitely go for the diagnosis. If blood, urine or imaging tests show that the person has developed tumor then surgery would be performed on him/her. A person who has a family history of Pheochromocytoma can also take the tests if he/she notices the aforementioned symptoms.

Are there any side effects?

Pregnant or lactating women are barred from taking the imaging test. In such cases blood pressure control routine is opted to prevent further damage.

What are the post-treatment guidelines?

Pheochromocytoma surgery is risky in that the blood pressure can rise to an abnormally high level when the patient is etherized. This condition is called hypertensive crisis. To prevent this situation from arising blood pressure control before and during the surgery is of utmost importance. A patient undergoing this surgery is advised to consult an endocrinologist who is qualified to devise methods for the treatment.

How long does it take to recover?

After the treatment the patient may develop bronchitis, pneumonia or urinary tract infection, all of which can be prevented by taking the prescribed medicines regularly. Surgery in the adrenal gland can lead to the cessation of the production of the steroids prerequisite for the body. Therefore, a patient might have to take steroid medications throughout his/her life post surgery. Apart from that he/she should also undergo blood tests annually.

What is the price of the treatment in India?

If a laparoscopic surgery is performed on the patient then it should not take more than 1 to 2 weeks to recover. However, in case of an adrenalectomy recovery time can extend to 4 weeks.

What are the alternatives to the treatment?

Pheochromocytoma treatment wards off the chances of the adrenal gland developing another tumor for a long time to come. However, the ailment can recur after 20 years and can develop either at the site or opposite to it. It can also develop in organs other than the adrenal gland. Therefore, a person who has undergone this surgery should stay under observation.

Safety: Condition Effectiveness: High Timeliness: High Relative Risk: Medium Side Effects: Low Time For Recovery: High Price Range:

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Popular Questions & Answers

I was feeling dizziness while waking up or sudden movement, doctor gave me verbet 16 but I have pheochromocytoma test next week and I saw in Google that this tablet is not good for patients who has pheochromocytoma ,what to do?

MBBS, Diploma in Otorhinolaryngology (DLO), DNB (ENT)
ENT Specialist, Gurgaon
It is BPPV avoid sudden jerky movement go for positional exercises at least for 6 mnth for compensation nd neurophyscian rather searching on google.

Can pheochromocytoma tumour i.e adrenal tumour 5 cm in size in all three dimensions be treated by medicines.

MBBS, MD - Medicine, MD - Oncology, Fellow of the Royal Society of Tropical Medicine and Hygiene (FRSTM & H)
Oncologist, Delhi
Dear lybrate-user, preferable is that the tumor should be removed by surgery. It is without any complication and any side effect from chemotherapy which will not surely get you rid of the tumor.

My mother in law is suffering from high blood pressure since many years. Her Age - 48 yrs. Weight - 65 kg. Her uterus was removed 10 years back. Her gall bladder was removed many years back. She had undergone many medical tests. Everything came out normal. She is taking so many medicines. But still sometimes her blood pressure shoots up. Since last couple of days its 180/100. She is feeling uneasiness, lethargic, weakness, neck pain all most all the time. She is self employed. Lives alone. Husband passed away long time back. Daughter married. She is taking Amtas 5 mg, Telday H 80 mg, Zabesta 2.5 mg, Aztolet (10+75), Minipress XL 10 mg, Rablet IT, Thyrox 75 mcg, CCM tab every day. Her Blood Urea & Creatinine Serum Creatinine 0.9 mg/dL, Urea Serum 20 mg/dL. FREE T4 - Serum 16.01 pmol/L. TSH Serum 4.38. Metanephirines 633.3 (24 hrs urine sample). Potassium- Serum 4.4. Sodium- Serum 131. Glucose-Plasma (Fasting) 91. Vitamin D Total- Serum 16. Her CT 128 Cardiac Angio was done. Findings- Normal. Aldosterone-Serum 13.90. CT Scan of whole abdomen (specially adrenal gland) was done. Fundings- No Adenoma, No Pheochromocytoma. Patchy calcification of hepatic parenchyma seen-likely, healed granuloma. Bilateral non obstructing renal calculi (at lower pole). No adrenal SOL identified. Stone found in left kidney.

MBBS
General Physician, Jalgaon
Please Ask her to. Go for morning and evening walk daily with relaxed mind Do neck, back and shoulders exercises daily Do meditation regularly Take salads, vegetable juices and soups more Continue her current medicine.

Table of Content

What is the treatment?
How is the treatment done?
Who is eligible for the treatment? (When is the treatment done?)
Who is not eligible for the treatment?
Are there any side effects?
What are the post-treatment guidelines?
How long does it take to recover?
What is the price of the treatment in India?
What are the alternatives to the treatment?