Common Specialities
{{speciality.keyWord}}
Common Issues
{{issue.keyWord}}
Common Treatments
{{treatment.keyWord}}

Nephrotic Syndrome: Treatment, Procedure, Cost and Side Effects

What is the treatment?

Nephrosis or nephrotic syndrome is a kidney disease characterized by oedema and large amounts of protein in the urine and usually increased blood cholesterol. It is associated with glomerulonephritis and swelling, especially around the eyes, feet, and hands and with various systemic diseases. When the kidneys' glomeruli are damaged, they allow 3 grams or more of protein to leak into the urine during a 24-hour period. As a result of the protein loss, the fluids start to accumulate in the body’s tissues. This causes swelling and puffiness.

Treatment of nephrotic syndrome includes addressing the underlying causes besides taking the necessary steps to reduce the symptoms like high blood pressure, oedema, high cholesterol, and the risks of infection. Treatment policies are different for children and adults. Treatment usually includes medications and changes in the diet of the patient.

The first treatment for nephrotic syndrome is called prednisolone, a steroid medicine. Vaccines are also supplied to lower the risk of diseases. Fluid retention in the tissues can be treated by reducing the amount of salt and water taken each day. Blood clots are treated with the necessary drugs that thin the blood. A high cholesterol level may be treated with dietary control (eating less fat), and in some cases with cholesterol lowering drugs. Children need to take diuretics, which is a type of medicine that helps to reduce swelling in the body (oedema).

How is the treatment done?

Prior to treatment, doctors will recommend blood and urine sample tests to evaluate the condition. Protein content in the urine can be evaluated by a dipstick that changes color when dipped in urine. Blood tests will reveal the amount of protein in blood, which in case of nephrosis, will be very low. Then, ultrasound and X-Ray of the kidneys are usually prescribed for better diagnosis. Once nephrotic syndrome has been established, doctors provide the necessary medicines to prevent it from relapsing.

Doctors may recommend a kidney biopsy. It is a procedure where tiny pieces of the kidney are removed using a needle for examination with a microscope. The biopsy may reveal the underlying disease. This helps the doctor to determine a course of treatment. If a person is diabetic, it is more likely that the disease is diabetic nephropathy. In this case, a biopsy is not necessary. Proper treatment of diabetes can reduce the degradation of health by nephrosis. Medications that lower blood pressure can also effectively slow the progression of kidney disease causing nephrotic syndrome. There are two types of blood pressure lowering medications. These are- angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs). Both of these have shown effective results in slowing the progression of kidney disease. Statin medications may be given to lower the cholesterol level. Patients with nephrotic syndrome should be given the pneumococcal vaccine. This helps protect against a bacterium that commonly causes infection and weakens the body further. Blood thinning medications are usually given only to people with nephrotic syndrome who develop a blood clot.

Who is eligible for the treatment? (When is the treatment done?)

Both children and adults are eligible for the treatment of nephrosis. In case of children, the treatment usually requires a longer duration. But for adults, the treatment is cured within eight to ten months without cases of further recurrence of proteins in urine.

Who is not eligible for the treatment?

People who do not experience any severe symptoms associated with nephrotic syndrome do not require medical treatment.

Are there any side effects?

The use of Corticosteroids for the treatment of nephrotic syndrome can cause mild side effects that fade away with time. But, a doctor should be contacted if the patient suffers any of the following. Side effects of nephrosis treatment include trouble in breathing, swelling of body parts like face, lips, tongue, or throat, problems in eyes, including blurred vision or eye pain. The person may also feel belly pain and nausea which refuse to go away, muscle cramps, changes in skin including acne and blemish. Side effects of corticosteroids also include changes in the stool color which turn bloody or blackish, sudden increase in the body weight along with frequent urges of drinking water.

What are the post-treatment guidelines?

In case of adults, relapses or recurrence of protein in urine are less common after treatment. But most children encounter at least one relapse even after full treatment. Each relapse requires a further course of steroid treatment for a shorter time.

Eating, diet and nutrition do not play any major role to prevent nephrosis. But, after the treatment, patients are advised to limit the intake of dietary sodium(salt). Fluids may be recommended to help reduce edema. Hyperlipidemia can be prevented by consuming a diet low in saturated fat and cholesterol. Nephrotic syndrome fades away with the proper use of steroids and the person starts to regain and live a normal life.

How long does it take to recover?

Nephrotic Syndrome or nephrosis is a chronic disease. It usually takes a long duration for its cure, which may vary from a few months to a few years. Most patients do well within about one year. But longer treatment may be required in certain resistant cases. Some cases may need treatment for more than five years. . Thus it is hard to predict exact timeline for its cure.

What is the price of the treatment in India?

Approximate expenditure for the treatment of nephrotic syndrome varies from Rs-500 to Rs 3000. For repeated treatments, the cost may be more.

Are the results of the treatment permanent?

The treatment is usually permanent in case of adults. After adolescence, nephrotic syndrome has lesser chances of relapse and recurrence. But in case of children, even after the best treatments, at least one relapse is obvious. During this phase, steroids are again provided but for a lesser duration as the proteins excreted are also lesser than initial. This may keep recurring for a series in case of child nephrosis. However, for a person who hasn’t suffered nephrosis for five years will not be affected by it again. So in these cases, the treatment is permanent.

What are the alternatives to the treatment?

Along with the conventional treatment of nephrotic syndrome, homeopathy treatment may also be used as an alternative. Homeopathic medicines are used in extremely small dose for a longer period of time and they are prepared through a process of potentization. This way the medicines become absolutely free from any side effects. Homeopathic treatment of nephrotic syndrome include reducing the frequency of attacks, its severity and duration and also the patient’s dependence on cortisone.

Safety: Medium Effectiveness: High Timeliness: High Relative Risk: High Side Effects: Medium Time For Recovery: High Price Range:

Rs 500- Rs 3000

Popular Health Tips

Chronic Nephritis - Signs To Watch Out For!

FIMSA, MD-Nephrology, DM - Nephrology, MD-Medcine, MBBS
Nephrologist, Delhi
Chronic Nephritis - Signs To Watch Out For!
Acute nephritis does not seem like a nice thing to have, does it? Well, the truth is that, as expected, it really isn t! It is, essentially, when the kidneys swell up. But what exactly causes acute nephritis? That answer is not all that simple! On...
2740 people found this helpful

Recommended Diet For Nephrotic Syndrome!

MBBS, MD (Med), DNB (Nephrology)
Nephrologist, Mumbai
Recommended Diet For Nephrotic Syndrome!
Nephrotic Syndrome is a condition which is characterised by the loss of protein into the urine (called proteinuria) as a result of increased glomerular permeability and oedema. This results in low protein level in the blood. The low levels of prot...
2940 people found this helpful

Nephrotic Syndrome: Causes and Treatment

MBBS, MD - Medicine, DM - Nephrology
Nephrologist, Delhi
Nephrotic Syndrome: Causes and Treatment
Glomerulonephritis is a disease that is caused due to inflammation of the small filters that are present within the kidneys or glomeruli. Glomeruli eliminate the excess waste, electrolytes and fluids from the blood, discharged through urine. A glo...
3194 people found this helpful

What Are The Symptoms, Diagnosis And Treatment Of Nephrotic Syndrome?

Fellowship- IPNA(Pediatric Nephrologist), Fellowship- ISPN, Diploma In Child Health (DCH), MBBS
Pediatrician, Delhi
What Are The Symptoms, Diagnosis And Treatment Of Nephrotic Syndrome?
The nephrotic syndrome refers to a kidney disease. Nephrotic syndrome is triggered when the glomeruli (tiny structures in the kidneys) malfunction or are damaged and allow too much protein to enter into the kidneys. Nephrotic syndrome is a chronic...
2586 people found this helpful

Nephrotic Syndrome Causes, Symptoms And Treatment In Hindi - नेफ्रोटिक सिंड्रोम के लक्षण, कारण और उपचार

Bachelor of Ayurveda, Medicine and Surgery (BAMS)
Ayurveda, Lakhimpur Kheri
Nephrotic Syndrome Causes, Symptoms And Treatment In Hindi - नेफ्रोटिक सिंड्रोम के लक्षण, कारण और उपचार
नेफ्रोटिक सिंड्रोम आम किडनी रोगों में से एक या रोगों का समूह कहा जा सकता है, इसमें किसी भी आयु समूह के शरीर पर सूजन होना इसके लक्षणों में से एक है. साथ ही इसमें पेशाब के दौरान प्रोटीन मात्रा का अधिक निकलना, रक्त में प्रोटीन की कमी, कोलेस्ट्रॉल का ...
4 people found this helpful

Popular Questions & Answers

Hi sir my daughter is suffering from disease nephrotic syndrome from last 1 year she is 2 year old girl child, she is suffering from march 2017. Want to know which treatment is best homeopathic, alopathic ,ayurveda I giving her alopathic and want to know how she is cure how much time kindly sugest.

DM - Nephrology, MBBS Bachelor of Medicine & Bachelor of Surgery, MD - Medicine
Nephrologist, Gurgaon
Dear Lybrate user. As I can understand that your daughter is now 2 years old and was diagnosed with nephrotic syndrome 1 years back at the age of 1 yr. Nephrotic syndrome is a condition where there is loss of lot of protein in the urine. Normally ...
12 people found this helpful

I am a nephrotic syndrome patient who have been advised to take azoran 100 mg. Does this medicine actually work and what are the worst case side effects,

MS - General Surgery, FMAS.Laparoscopy
General Surgeon, Gandhinagar
Hello dear Lybrate user, Warm welcome to Lybrate. I have evaluated your query thoroughly. As per your condition, you requires immuno suppressent medication which is best in form of azoran.* there are certain side effects which can be vary from per...
1 person found this helpful

My daughter, suffering "nephrotic syndrome" from last 5 years, Albumin +++, RBC 04-06 /HPF, Pus cells 12-16/HPF, epithelial cells present (+), S.Albumin 16 out of 35. Need your advice.

Bachelor of Unani Medicine and Surgery (B.U.M.S)
Ayurveda, Kanpur
Basant Kusumakar Ras 125 Mg Twice a Day Gokshuradi Avleh 2-3 Gm Twice a Day Relief In 5-6 Days and for Complete Cure Take it for 60 Days Only Avoid Oily and Spicy Food

I am suffering from nephrotic syndrome since 2012 my protein running out of urine 2 + sometime RBC also I am taking some electropathy medicines.

BHMS
Homeopath, Hooghly
If u wants to cure ur problem permanently then u have to do proper homoeopathic treatment,,avoid taking high protein

Table of Content

What is the treatment?
How is the treatment done?
Who is eligible for the treatment? (When is the treatment done?)
Who is not eligible for the treatment?
Are there any side effects?
What are the post-treatment guidelines?
How long does it take to recover?
What is the price of the treatment in India?
Are the results of the treatment permanent?
What are the alternatives to the treatment?
Play video
Nephrotic Syndrome
Hi, I am Dr. Yogesh Kumar Chhabra, Nephrologist. Aaj me baat krunga nephrotic syndrome ke bare me. Is problem me urine ki quantity badh jati hai, swelling ho jati hai, hypertension ho jata hai. Ye problem mainly bachon me dekhi jati hai. Jo bache ...
Play video
Nephrotic Syndrome
Hello, I am Dr. Amit Agawal, a pediatric nephrologist. Bachon ki kidney disease ka me treatment deta hun. Aaj me apko btaunga nephrotic syndrome ke bare me. Isme bachon ke urine me bhuut sara protein ane lgta hai. Protein ki kami ho jati hai and s...
Having issues? Consult a doctor for medical advice