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Exocrine System (Human Anatomy): Image, Functions, Diseases and Treatments

Last Updated: Feb 02, 2023

Exocrine System Image

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Your exocrine system is made up of a network of glands located throughout your body. Sweat, breast milk, mucus, and oil are all secreted by these glands and assist your organs work. Your exocrine system differs from your endocrine system in that it secretes these compounds through ducts. Cancer, inflammation, and hair loss are all examples of exocrine system disorders.

Your exocrine system is made up of glands that are distributed throughout your body and perform a range of activities. It is a component of the autonomic nervous system that controls automatic, health-promoting behaviours.Glandular structures are small organs that produce chemicals that initiate specific biological processes. For instance, your salivary glands create saliva to maintain a moistened mouth.

What is the difference between the endocrine and exocrine systems?

Your endocrine system: Hormones are secreted by endocrine glands and released into the bloodstream right away. The blood then transports hormones to specific tissues.Exocrine glands produce chemicals into ducts, which transport these substances to the surface of target tissues.

What areas of the body do the exocrine glands support?

Exocrine glands regulate particular processes in your skin, hair, breasts, pancreas, mouth (particularly saliva production), and small intestine (duodenum).

What is the anatomy of the exocrine system?

The exocrine system is the part of the body's anatomy that is responsible for producing and secreting substances outside of cells. This system includes a variety of glands that produce and secrete substances such as hormones, enzymes, and mucus.

The exocrine system consists of various glands that produce and secrete substances such as hormones, enzymes, and mucus. These glands include sweat glands, which produce sweat to regulate body temperature; sebaceous glands, which produce sebum to lubricate and protect the skin and hair;

salivary glands, which produce saliva to moisten and soften food in the mouth and aid in digestion; pancreatic glands, which produce enzymes to help digest carbohydrates, proteins, and fats in the small intestine; the liver, which produces bile to aid in the digestion of fats; the lungs, which produce mucus to keep the airways moist and clear of debris; and mammary glands, which produce milk to feed infants.

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Exocrine System Functions

  • Glands in the exocrine system perform a range of tasks.
  • Milk is produced by mammary glands.
  • Mucus is produced by mucinous glands to cover and protect fragile tissue.
  • Your skin and hair's surface are covered with an oily material that is produced by sebaceous glands.
  • Sweat and saliva are examples of the watery liquids that serous glands generate.

What are the functions of the exocrine system glands?

Depending on where they are, glands in the exocrine system do many important things:

  • Breasts: The modified serous glands called mammary glands help a woman breastfeed (chestfeeding). They give milk to babies that helps them grow and strengthens their immune systems.
  • Mouth: Saliva is made by glands in many parts of your mouth. Your saliva maintains the moisture and health of your mouth and throat. In addition to this, it assists in the breakdown of carbohydrates, which gets the digestive process off to a healthy start.In addition, your mouth has glands that produce mucinous secretions, which make it simpler for you to swallow items.
  • Pancreas: The pancreas has a role in both digestion and hormone production. It's an exocrine gland, thus it secretes chemicals that prevent stomach acid from doing damage. To further aid digestion, it produces digestive enzymes that work on protein, fat, and carbohydrate molecules.Insulin and glucagon are two hormones that are secreted by the pancreas, which are responsible for maintaining healthy blood sugar levels.
  • Skin and hair: The serous glands are responsible for perspiration.Sweat glands are classified into two types. Sweat glands that produce eccrine sweat may be found pretty much anywhere on the surface of your skin. Because apocrine sweat glands secrete a fatty material when you perspire, you are able to maintain a colder body temperature for a longer period of time.Sebaceous glands are responsible for the production of oil, which in turn creates moisture that helps to preserve the skin and hair.
  • Small intestine: Mucosal glands, also known as Brunner's glands, are the glands that are responsible for the production of a substance that serves as a barrier between the small intestine and the acid that is generated by the stomach. This material is crucial for protecting the small intestine. In addition to this, it encourages the synthesis of enzymes, which are essential for the breakdown of carbohydrates and the digestion and uptake of nutrients in the body.

Exocrine System Conditions and Disorders

  • Breast cancer: A kind of cancer that begins in the cells of the breast and can spread to other organs. It is the type of cancer that affects women more frequently than any other type.
  • Breast pain (mastalgia): Experiencing pain or discomfort in the chest or around the nipple area. It is conceivable that this is an indication of another condition, such as breast cancer, among a number of others.
  • Ductal carcinoma in-situ: A subtype of non-invasive breast cancer in which abnormal cells are discovered in the lining of the breast ducts, but the disease has not yet gone beyond the ducts itself.
  • Fibroadenomas of the breast: Breast tissue can sometimes get infected with benign tumours, which are distinct from malignant growths. They often have a round or oval form, and the most common people who have them are young ladies under the age of 30.
  • Mammary duct ectasia: A condition in which the mammary ducts (the tubes that carry milk from the breast to the nipple) become dilated and blocked, causing fluid to build up and sometimes leading to infection.
  • Mastitis: Inflammation of the breast tissue, often due to infection. It is more common in women who are breastfeeding, but can also occur in women who are not breastfeeding.
  • Pancreas gland conditions: Various conditions that can affect the pancreas gland, a gland located in the abdomen that produces hormones and enzymes that help with digestion.
  • Pancreatic cancer: including ductal adenocarcinoma: A type of cancer that affects the pancreas gland. The form of pancreatic cancer that occurs most frequently is called ductal adenocarcinoma.
  • Pancreatitis: Pancreatic gland inflammation. It can be either acute (rapid and severe) or chronic (long-lasting).

Salivary Gland Conditions

  • Salivary gland cancer: A form of cancer that originates in the salivary glands, which are the glands found in the mouth and throat that are responsible for producing saliva.
  • Sjögren's syndrome: A condition characterised by dryness of the eyes, lips, and other areas of the body that is caused by an autoimmune illness. In addition to these symptoms, it is also possible for it to produce joint discomfort and exhaustion.

Skin Gland Conditions

  • Hormonal acne: Acne that is brought on by shifts in hormone levels, such as those that occur during puberty, pregnancy, or menopause, as an example.
  • Hyperhidrosis: A medical disorder that causes abnormally high levels of perspiration, particularly in the palms, soles of the feet, and armpits.
  • Body odour (bromhidrosis): A pungent odour that is caused by bacteria that dwell on the skin and feed off of perspiration.
  • Hair loss (alopecia): A disorder characterised by the loss of hair, most frequently in discrete patches. It is possible for it to spread to other parts of the body in addition to the scalp.
  • Ear wax buildup and blockage: A condition in which ear wax accumulates in the ear canal and blocks the ear, leading to hearing problems and other symptoms.

Small Intestine Conditions

  • Rare, noncancerous tumours: Tumours that are not cancerous (benign) and are uncommon or rare.
  • Brunner's gland hamartoma: A rare, noncancerous tumour that develops in the Brunner's glands, which are small glands found in the small intestine.
  • Brunner's gland adenoma: A rare, noncancerous tumour that develops in the Brunner's glands, which are small glands found in the small intestine.
  • Diabetes: Diabetes mellitus is a chronic illness in which the body is unable to manage blood sugar levels in an appropriate manner. It is possible for it to result in a variety of consequences, some of which include injury to the nerves, blood vessels, and organs.
  • Cystic fibrosis: a genetic disorder that can impair any of the body's functions, including the respiratory, digestive, and reproductive systems. A mutation in the gene that regulates the synthesis of a protein known as cystic fibrosis transmembrane conductance regulator causes it (CFTR).

Pancreas conditions

  • Pancreatic cancer: A type of cancer that affects the pancreas gland, a gland located in the abdomen that produces hormones and enzymes that help with digestion.
  • Pancreatitis: Pancreatic gland inflammation. It can be either acute (rapid and severe) or chronic (long-lasting).
  • Pseudocyst: A fluid-filled sac that forms in the pancreatic gland, usually as a consequence of pancreatitis. It is not a real cyst since it lacks a lining.

Exocrine System Tests

  • Physical examination: A routine medical examination in which a healthcare provider checks the body for signs of illness or injury.
  • Computed tomography (CT) scan: A kind of medical imaging that creates detailed pictures of the interior of the body by employing x-rays in conjunction with a computer.
  • Magnetic resonance imaging (MRI): A kind of imaging used in medicine that creates detailed photographs of the inside of the body by combining a strong magnetic field with radio waves.
  • Endoscopic retrograde cholangiopancreatography (ERCP): Endoscopy is a treatment that involves inserting a thin, flexible tube (endoscope) into the mouth and into the digestive tract to inspect the bile ducts and pancreatic gland.
  • Blood tests: Tests that test numerous blood constituents such as hormones, enzymes, and proteins. They can be used to diagnose a wide variety of medical disorders.
  • Sweat chloride test: A test that measures the level of chloride in sweat to diagnose cystic fibrosis, a genetic disorder that affects the respiratory, digestive, and reproductive systems.
  • Genetic testing: Tests that are used to identify genetic variations or mutations that may be associated with a particular condition or disease.
  • Magnetic resonance cholangiopancreatography (MRCP): A medical imaging technique that produces comprehensive pictures of the bile ducts and pancreatic gland using a high magnetic field and radio waves.
  • Fine needle aspiration cytology (FNAC): A process that involves inserting a tiny needle into a lump or tumour and extracting a small sample of cells for inspection under a microscope. It is frequently used to diagnose and monitor cancer.

Exocrine System Treatments

Treatments for Pancreas

  • Insulin injection: A method of delivering insulin, a hormone that helps regulate blood sugar levels, into the body through a needle and syringe. It is often used to treat diabetes.
  • Pseudocyst drainage: A procedure in which a pseudocyst, a fluid-filled sac that develops in the pancreas gland, is drained using a needle or tube.
  • Islet cell transplantation: A procedure in which cells from the pancreas gland (islet cells) are transplanted into the liver of a person with type 1 diabetes to help regulate blood sugar levels.
  • Pancreatic stenting/pancreatic endotherapy: The procedure that involves inserting a tiny tube (stent) into the pancreatic gland to assist drain fluids or alleviate obstructions.
  • Pancreatic endotherapy: It refers to a variety of treatments that are carried out with the help of an endoscope, which is a thin, flexible tube with a light and camera on the end. These techniques might be used to treat pancreatitis or pancreatic cancer.

Treatments for Salivary gland

  • Sublingual gland surgery: A surgical procedure to remove the sublingual gland, a salivary gland located under the tongue.
  • Submandibular sialadenectomy: A surgical removal of the submandibular gland, which is a salivary gland found beneath the jaw.
  • Radiation therapy: A treatment that uses high-energy radiation to kill cancer cells or shrink tumors. It may be used to treat salivary gland cancer or other conditions.
  • Superficial or lateral or classical parotidectomy: A superficial or lateral parotidectomy involves removing the gland through an incision made in the skin behind the ear, while a classical parotidectomy involves removing the gland through an incision made in the neck.

Treatments for Skin

  • Laser therapy: A treatment that uses a focused beam of light to remove or destroy tissue, such as a tumour or scar tissue. It has shown promise in the treatment of a wide range of illnesses, including cancer, as well as ailments affecting the skin and the eyes.
  • Skin graft: A surgical procedure in which a piece of healthy skin is taken from one area of the body and transplanted to another area to cover a wound or area of damaged skin.

Exocrine System Medicines

  • Steroids for reducing inflammation of Exocrine System: Steroids are medications that are used to reduce inflammation in the body. Some examples of steroids that may be used to treat inflammation of the exocrine system include prednisone, methylprednisolone, and hydrocortisone.
  • Muscle relaxants for stiffness in Exocrine System: Muscle relaxants are medications that are used to relieve muscle stiffness and spasms. Important examples of muscle relaxants that may be used to treat stiffness in the exocrine system include cyclobenzaprine, carisoprodol, and methocarbamol.
  • Antivirals for treating infection of Exocrine System: Antivirals are a class of medicines that are employed in the treatment of illnesses brought on by viruses. Valacyclovir and acyclovir are two examples of antivirals that might be utilised in the treatment of an infection that has shown itself in the exocrine system.
  • Chemotherapeutic medicines for Exocrine System: Chemotherapeutic medicines are medications that are used to treat cancer. Some examples of chemotherapeutic medicines that may be used to treat conditions of the exocrine system include gemcitabine and fluorouracil (5-FU).
  • Anti-inflammatory drugs: Anti-inflammatory drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs), can be used to decrease pain and swelling and lower glandular inflammatory response in the exocrine system.
  • Antibiotics: Antibiotics, such as penicillins and cephalosporins, are effective in treating exocrine gland infections.
  • Hormones: Hormones, such as insulin and thyroid hormone, may be used to control how hormone-producing glands like the thyroid and pancreas operate in the exocrine system.
  • Cholinergic drugs: Cholinergic drugs, such as pilocarpine, may be used to increase glandular secretion production and secretion, such as saliva and perspiration, in the exocrine system.

How do I care for my exocrine system?

An important part of maintaining a healthy exocrine system is taking care of oneself. You may do this by engaging in regular physical activity, eating a diet rich in protein, fruits, and vegetables while limiting your intake of saturated fats and processed foods, consuming an adequate amount of water, cutting back on alcohol, and giving up cigarettes. Frequent checkups with your doctor are essential, and so are regular screenings, such as mammograms to detect breast cancer.

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Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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Reviewed ByDr. Bhupindera Jaswant SinghMD - Consultant PhysicianGeneral Physician

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