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Aplastic Anemia: Treatment, Procedure, Cost and Side Effects

What is the treatment? How is the treatment done? Who is eligible for the treatment? (When is the treatment done?) Who is not eligible for the treatment? Are there any side effects? What are the post-treatment guidelines? How long does it take to recover? What is the price of the treatment in India? Are the results of the treatment permanent? What are the alternatives to the treatment?

What is the treatment?

Aplastic anemia is a condition in which your body stops producing sufficient blood cells. It can result in extreme fatigue, high risk of blood infections and uncontrolled bleeding. Slowing down or stopping of the production of blood cells can occur due to damage caused to the bone marrow. Bone marrow, that produces stem cells in the body, can get temporarily or permanently injured due to extensive radiation or chemotherapy, use of certain drugs, viral infection and exposure to toxic chemicals. Some mild cases can be treated by over the counter medications whereas severe cases may need to be treated after hospitalization. Blood transfusion or stem cell transplant are some treatments available for treating aplastic anemia.

How is the treatment done?

Bone marrow stimulant drugs like sargramostim, filgrastim, pegfilgrastim and epoetin alfa help in stimulating the bone marrow to produce new blood cells. Generally, blood transfusions are done to control bleeding and relieve anemia symptoms. They do not really cure aplastic anemia but can provide blood cells that your bone marrow is not producing. You may have to undergo several blood transfusion sessions depending on your condition. Stem cell transplant is the only permanent treatment for people suffering from aplastic anemia. The bone marrow is rebuilt from the stem cells of a donor. Firstly, your diseased bone marrow will be depleted by radiation or chemotherapy. Healthy stem cells of the donor will then be injected intravenously into the blood stream. They migrate to the bone marrow cavities and start generating new blood cells. It is not easy to find a suitable donor. Also, in some cases your body might reject the treatment leading to life threatening situations.

Who is eligible for the treatment? (When is the treatment done?)

If you experience frequent and prolonged infections, rapid or irregular heart rate, constant dizziness, headache and fatigue, nosebleeds and bleeding gums or prolonged bleeding from cuts; you must consult a doctor and get your condition thoroughly checked.

Who is not eligible for the treatment?

Everybody is a candidate for stem cell transplant or can find a donor. Generally, only young people are able to go through it successfully.

Are there any side effects?

Bone marrow stimulant drugs may cause temporary redness, irritation or itching in your skin. Your body might reject stem cell transplant and result in life threatening conditions.

What are the post-treatment guidelines?

The drugs that you consume before and after the treatment may weaken your immune system. You must see a doctor at the very first sign of infection, such as fever. Do not ignore any such signs. Avoid outdoor activities that may result in cuts or falls. Try to maintain good hygienic conditions. Keep distance of sick people. Wash your hands regularly. Take all precautions so as not to catch any infection.

How long does it take to recover?

Time period of recovery depends on the severity of your condition.

What is the price of the treatment in India?

Bone marrow transplant can cost between ₹2000000 - ₹3500000.

Are the results of the treatment permanent?

The results of the treatment may or may not be permanent. In many cases, aplastic anemia may return as soon as you stop taking the prescribed drugs.

What are the alternatives to the treatment?

There are no alternatives to this treatment.

Popular Questions & Answers

Hello, I have aplastic anemia, it's been almost 2 months since I got diagnosed, no treatment yet, and I would like to know if mine's severe or not, and what treatment should I take, cause doctors haven't decided yet, the last blood test I did showed that my red blood cell count is at 2.3 my white blood cell count 1.99 and my platelets 21.000, although I must say at one point my platelets were 19.000, I have only been getting blood transfusions. Thank you for answering.

Fellowship In Leukemia & Stem Cell Transplant, DM - Clinical Haematology, MD - Medicine
Hematologist, Nagpur
Need to do bone marrow test and also find if this is constitutional bone marrow failure. Severity depends on CBC and marrow report. If this is aplastic Anemia don't wait to start the therapy.
1 person found this helpful

Sir mera hemoglobin 11.2 hai to usko badane ke liye kya karna padega please answer.

CCEBDM, PG Diploma In Clinical Cardiology, MBBS
General Physician, Ghaziabad
Take Spinach, beet root, tomato, pomegranate, apple, dates, soybean,egg, whole grain atta, honey, nuts, raisins, Medicine can not be advised for open question, for medicine contact on private chat.

Hi, I am 36 years old F, got all my blood tests done, and found out the HB is low ard 8, Vit B12 is also low just 65, and so was Vit D, I hv severe period flow once in 3 months which lasts up to 4- 6 wk. Which is the main cause of low HB. I do hv PCOD n thyroid (125 mg dose) too. Please guide.

MBBS
General Physician, Mumbai
Apart from taking symptomatic treatment I will suggest you to take injection vitcofol 2cc intramuscularly every alternate days for five pricks over the buttocks through a health professional

One patient age 62 years suffering from bubble boy which medicine we can take or any check up please tell me.

M.D. Consultant Pathologist, CCEBDM Diabetes, PGDS Sexology USA, CCMTD Thyroid, ACDMC Heart Disease, CCMH Hypertension, ECG
Sexologist, Sri Ganganagar
Treatments for Bubble boy disease (SCID) include: Bone marrow transplant Intravenous immunoglobulin (IVIG)

I am a women of age 31 years. And im suffering from aplastic anemia. Cam I suggest any solution?

MD, DM - Clinical Haematology
Hematologist, Ludhiana
Hello lybrate-user Yes there are solutions for aplastic anaemia. The most appropriate one depending on your disease severity will be to consider exploring options for a bone marrow transplant. Other therapies include use of dugs like ATG and cyclo...
1 person found this helpful

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