I am cancer patient I am suffering from apml cancer I want to ask that I will marry in future or not.

Question

Without treatment, APML has a very short median survival of less than one month resulting from uncontrolled bleeding. However, with modern therapy, APL is associated with the highest proportion of patients who are presumably cured. Patients younger than age 30 years and those who present with a white blood cell count less than 10,000, have superior event-free survival. Adverse risk factors a total white blood cell count greater than 10,000 and a platelet count less than or equal to 40,000. Using these two parameters, three prognostic categories could be distinguished, with the following estimated probabilities of three-year relapse-free survival (RFS): -Low risk: WBC <10,000 and platelets >40,000; RFS 98 percent -Intermediate: WBC <10,000 and platelets <40,000; RFS 89 percent -High risk: WBC >10,000; RFS 70 percent These three risk groups originally proposed by the PETHEMA group can be collapsed into two groups based entirely on the WBC count (< or >10,000 at diagnosis). That is, the platelet count is not necessary to distinguish a low/intermediate risk group when arsenic trioxide is used early in therapy. Studies have demonstrated that patients in this risk group have superior outcome when treated with All Trans Retinoic Acid (ATRA) plus arsenic trioxid in comparison to ATRA plus anthracycline-based chemotherapy. In short, if you are in the low or intermediate risk group, the prognosis is good. With cure rates of 80-90%. Obviously nobody can give a guarantee of cure. Marriage does not depend on your cure rate. It depends on the outlook of you and your partner. Life is any ways unpredictable. It is your decision. Feel free to contact me directly if you want to discuss this further.

Nikhilesh Borkar · Accepted Answer

Without treatment, APML has a very short median survival of less than one month resulting from uncontrolled bleeding. However, with modern therapy, APL is associated with the highest proportion of patients who are presumably cured. Patients younger than age 30 years and those who present with a white blood cell count less than 10,000, have superior event-free survival. Adverse risk factors a total white blood cell count greater than 10,000 and a platelet count less than or equal to 40,000. Using these two parameters, three prognostic categories could be distinguished, with the following estimated probabilities of three-year relapse-free survival (RFS): -Low risk: WBC <10,000 and platelets >40,000; RFS 98 percent -Intermediate: WBC <10,000 and platelets <40,000; RFS 89 percent -High risk: WBC >10,000; RFS 70 percent These three risk groups originally proposed by the PETHEMA group can be collapsed into two groups based entirely on the WBC count (< or >10,000 at diagnosis). That is, the platelet count is not necessary to distinguish a low/intermediate risk group when arsenic trioxide is used early in therapy. Studies have demonstrated that patients in this risk group have superior outcome when treated with All Trans Retinoic Acid (ATRA) plus arsenic trioxid in comparison to ATRA plus anthracycline-based chemotherapy. In short, if you are in the low or intermediate risk group, the prognosis is good. With cure rates of 80-90%. Obviously nobody can give a guarantee of cure. Marriage does not depend on your cure rate. It depends on the outlook of you and your partner. Life is any ways unpredictable. It is your decision. Feel free to contact me directly if you want to discuss this further.