Retinoic acid is an important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia. For acne it is applied to the skin as a cream or ointment. For leukemia it is taken by mouth for up to three months.
Topically this medication is only for use on skin and it should not be applied to eyes or mucosal tissues. Common side effects include skin irritation, redness, swelling, blistering, headache, Irritability, nausea, vomiting, hypersensitivity, Dry skin, Weight loss, Transient hydrocephalus, Hypercalcemia, skin cracking, HypervitaminosisDo not take this medication if you are allergic to it.
Is It safe with alcohol?No interaction found
Are there any pregnancy warnings?Retinoic Acid is highly unsafe to use during pregnancy.
Human and animal studies have shown significant adverse effects on the foetus. Please consult your doctor.
Are there any breast-feeding warnings?Retinoic Acid is safe to use during lactation. \nHuman studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Is it safe to drive while on this medicine?It is not known whether Retinoic Acid alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Does this affect kidney function?There is limited information available on the use of Retinoic Acid in patients with kidney disease. Please consult your doctor.
Does this affect liver function?There is no data available. Please consult doctor before consuming the drug.
Are there any missed dose instructions?If you miss a dose of Retinoic Acid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Below is the list of medicines, which contains Retinoic Acid as ingredient
This medication works by binding to the retinoic acid receptor. This RAR is found to be bound to DNA in a heterodimer form with the retinoid X receptor. This is present in the region named retinoic acid response elements, also known as RAREs. This binding leads to the regulation of genes targeted, controlling a variety of cell types differentiation.
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