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Overview

Fibrinogen Test

Fibrinogen Test

also known as: Factor I Antigen , Fibrinogen Level

The Fibrinogen blood test is known by names such as Factor I, Fibrinogen Activity, Functional Fibrinogen, Fibrinogen Antigen, Plasma Fibrinogen, and Hypofibrinogenemia Test. This is usually done to determine the fibrinogen levels in the blood. Fibrinogen happens to be an essential protein that helps the blood to clot and this helps the body to heal wounds faster. The fibrinogen activity test is conducted to measure the function of the fibrinogen in the blood. The result of this test is reported as the protein concentration in the blood.

A blood sample is needed for this test, however, no special preparation is required, unless the doctor says so. People taking any special medication like blood thinners may be asked to stop it. It is better to wear some comfortable clothing with sleeves that can be easily rolled up to enable easy drawing of blood from the arm. Kindly check with the doctor and the lab assistant for any specific procedures to be followed.

This test is advised when someone has prolonged or unexplained bleeding, thrombosis, etc. where the doctor suspects issues with blood clotting. The normal reference range for this test result is 200 to 400 mg/dL (2.0 to 4.0 g/L). Decreased fibrinogen activity may be due to insufficient or dysfunctional fibrinogen and further tests may be ordered. Chronically low levels may indicate reduced production of fibrinogen due to conditions such as afibrinogenemia or hypofibrinogenemia, end-stage liver disease or severe malnutrition. Acutely low levels may indicate consumption of fibrinogen as in the case of disseminated intravascular coagulation (DIC) and abnormal fibrinolysis. Elevated levels are seen with acute infections, coronary heart disease, pregnancy, stroke, trauma, cancer, etc. People with elevated levels have greater chances of developing cardiovascular diseases over time.

The procedure is a simple one, where the blood sample is taken from your arm and can be done at any doctor’s clinic, laboratory, etc. The lab assistant will clean the site on the arm with a swab of alcohol. A fresh needle is then inserted into a vein in your arm with a tube attached to collect the blood. The needle is removed once enough blood has been drawn. The tube is sealed and labelled and sent to the laboratory for analysis. The site from where the blood was drawn will be covered with a gauze pad.

LimitationsFibrinogen is an acute-phase reactant and can often become significantly increased in conditions involving tissue damage, infection, or inflammation.1 Increased levels may be seen in smokers, during pregnancy, and in women taking oral contraceptives.1 Fibrinogen levels can be diminished in advanced liver disease.4 Very high levels of heparin, direct thrombin inhibitors, or fibrin breakdown products may falsely reduce fibrinogen levels because they interfere with the rate of clot formation.1 Lipemia or hemolysis may interfere with this assay.
Specimen
Plasma, frozen
Volume
1 mL
Container
Lavender-top (EDTA) tube or blue-top (sodium citrate) tube.
Type Gender Age-Group Value
Fibrinogen
Unisex
All age groups
150 - 400 mg/dl
Average price range of the test is between Rs.500 to Rs.1700 depending on the factors of city, quality and availablity.

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Popular Questions & Answers

My husband was detected kidney cancer and his one kidney was taken out last week, please suggest me diet and what care should be taken.

MCh Urology, DNB Urology, MS-General Surgery, MBBS, Diploma In Laproscopy & Urology, Basic & Advance Robotic Urology Training
Urologist, Delhi
Avoid any painkillers in future except paracetamol and tramadol Drink plenty of water normal diet reduce red meat if non veg regular S CREATININE test 6 monthly.
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Popular Health Tips

White Vs Green Tea - Which One Is More Beneficial?

Diploma In Nutrition & Health Education
Dietitian/Nutritionist, Ahmedabad
White Vs Green Tea - Which One Is More Beneficial?

When it comes to health benefits, green tea has been an undisputed winner for a long time. It is a must have for all health conscious people. For many people, the day starts and ends with a cup of green tea. However, of late, its position and popularity have been challenged. With its health benefits, white tea is slowly but steadily finding its way into the lives of people.

Now the obvious question is; which one of the two (green tea or white tea) is better? While some loyal fans swear by green tea, others have genuine reasons to opt for white tea. To know more about their benefits, one first needs to know, what are green and white tea?

Green tea and white tea are both extracted and processed from the same mother plant, Camellia sinensis. White tea is manufactured using the young buds and leaves. Green tea, on the other hand, is manufactured from the older leaves of the plant.

Also, green tea undergoes more processing compared to the white tea. In the case of green tea, the leaves are first withered, followed by steaming or frying (pan frying). Next, there is rolling, shaping, and finally drying of the leaves. In the case of white tea, the processing is simple and involves steaming followed by drying of the leaves.

The health benefits of green tea Vs white tea

  1. The antioxidant capacity: Both green tea and white tea contains a phytochemical, Polyphenols, which has antioxidant properties. In addition to the weight management, this antioxidant is known to protect the body from cardiovascular disorders, diabetes, and even cancer. Research suggests the phenolic content, and subsequently, the antioxidant capacity is higher in white tea as compared to the green tea.
  2. Protection from UV rays: The harmful effects of UV rays are known to all. Research suggests that both green and white tea are at par (photoprotection ability) when it comes to protection from the harmful UV radiation.
  3. Anti-carcinogenic property: When it comes to cancer-fighting ability, white tea earns the brownie point. Undergoing less processing as compared to the green tea, the antimutagenic and the anti-carcinogenic properties are higher in white tea.
  4. Mood enhancer and stress reliever: Many studies suggest that white tea has a slightly higher caffeine content compared to the green tea. Thus, white tea will have a better soothing and refreshing effect than green tea.
  5. A younger looking skin: Both white and green tea play a pivotal role in slowing down the aging process. However, White tea contains a higher content of polyphenols (due to less processing) and is believed to have a better ability to prevent the breakdown of the elastin and collagen than green tea. The EGCG or EpiGalloCatechin Gallate (lowers the aging process) is also higher in white tea.
  6. Weight Management: When it comes to weight management, both white and green tea exhibit almost similar effects.
  7. Anti-inflammatory property: The anti-inflammatory property is slightly higher in white tea than green tea. White tea, thus, helps to suppress the activities collagenase, elastase, and oxidants (enzymes responsible for Rheumatoid arthritis) better. If you wish to discuss about any specific problem, you can consult a Dietitian/Nutritionist.
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