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My mother age 68 years has been diagnosed for Metastatic poorly differentiated adenocarcinoma as per report dtd 12-Mar-2018. The Mri dorsal spine dtd 13-feb-2018 shows collapse of d3, d7 vertebral body. Lesions on D3, D7, D12 spinal area. PET CT report 23-feb-2018 is also available. She is under the treatment of Doc. from Dharamshila hospital. According to them all treatment is going to be palliative, no cure is available. Accordingly, she was advised 10 RT and 6 chemotherapy. RT has been completed. EGFR, ALK, ROS1 by fish, PDL1 by ihc reports have come and EGFR mutation is positive. The doctor has advised Xovoltib 40 mg (afatinib dimaleate)/ Geftib 250 mg (gefitinib). No CT is to be done. After RT she has difficulty in swallowing food. Earlier she was taking Dexona 4 mg/Forcan as advised by once radiologist Dr. , after RT was done. She Has intermittent fever around 100. Has started reported pain and stiffness in back for the past few days. Right now, she has pain in her upper back and shoulder, though not very acute. She has difficulty in holding up things, but is currently active and mobile. Food habits are moderate to light, there is no change in that. No significant weight loss is observed as of now. She is a patient of High BP, has glaucoma and cataract also. She has developed slight incontinence now, and bowel movements have become very irregular. If any more information is required please let me know. I shall be extremely grateful for your support and advise in this matter.

1 Doctor Answered
I presume she is lung cancer patient, although you have not mentioned the same (as you wrote she is EGFR positive, ALK4 and ROS1 and PDL1 are done in lung) Geftinib is an EGFR inhibitor given in lung cancer EGFR +ve, with good response rates. It does cause diarrhoea and rash in a few patients though. If she has other symptoms, treat her symptomatically. We try to prolong their life by giving palliative treatment, which may be months to few years in exceptional cases. But cure is not a target.
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