Bunase 0.5mg Respules 2ml
Bunase 0.5mg Respules 2ml is a medication of the corticosteroid type that reduces inflammation in the body. It is available as a nasal spray, inhaler, pill and rectal form. For long-term management of asthma and chronic obstructive pulmonary disease, the inhaler is used.
The nasal spray is used for nasal polyps and allergic rhinitis. The pill in a delayed release form and rectal form treat various inflammatory bowel diseases including ulcerative colitis, Crohn’s disease and microscopic colitis.
There are a few side effects to taking this medicine as an inhaler which may include respiratory infections, cough, and headaches. Common side effects with the pills include vomiting, feeling tired and joint pains. Serious side effects include an increased risk of infection, cataracts and loss of bone strength.
Long-term use of the pill form may result in adrenal insufficiency. Stopping the use of the tablet suddenly after long-term use may therefore be dangerous. It is advised to use the inhaler form during pregnancy as it is considered to be a safer option.
Bunase 0.5mg Respules 2ml is not prescribed to anyone younger than 18 years old, anyone having allergy, or anyone who is breastfeeding. If you are pregnant or plan to become pregnant, make sure you inform your doctor before taking this medicine.
Also inform your doctor if you have or have had tuberculosis, a serious bacterial, viral, or fungal infection, a weak immune system, high blood pressure, cataracts, cirrhosis or other liver disease, stomach ulcer, low bone mineral density, eczema, a personal or family history of diabetes or glaucoma.
Dosage is different for different people depending on their medical condition, the intensity of the medical condition, the age of the patient and so on. Do not intake more amounts of Bunase 0.5mg Respules 2ml than prescribed. Rinse your mouth after the inhalation to prevent mouth infections. Consult the doctor if you experience any serious side effects or if you suspect an overdose.
Symptoms of overdose include irritation and burning of the nasal mucosa, sneezing, intranasal and pharyngeal Candida infections, nasal ulceration, epistaxis, rhinorrhea, nasal stuffiness, headache.
When consumed in excessive quantities, systemic hypercorticism and adrenal suppression may occur, in those cases discontinuation and withdrawal of the corticosteroid should be done judiciously.
Use as directed; do not increase dosage or discontinue abruptly without consulting prescriber. It may take several days for you to realize full effects of treatment. If you are also using an inhaled bronchodilator, wait 10 minutes before using this steroid aerosol.
The medication is primarily used for the following conditions:
How long is the duration of effect?The effect of this medicine lasts for an average duration of 6 to 11 hours.
What is the onset of action?The peak effect can be observed in 5 to 10 hours after an oral dose and 30 minutes after an inhaler.
Are there any pregnancy warnings?The inhaler is recommended in the pregnant women. The oral form of this medicine is not recommended for pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
Is it habit forming?No habit forming tendency has been reported
Are there any breast-feeding warnings?The oral form of this medicine is known to excrete through the breastmilk. Therefore, not recommended in breastfeeding women unless necessary. The amount of inhaled medicine is excreted in negligible amounts in breastmilk. Therefore, can be used in breastfeeding women.
Is It safe with alcohol?The effect of consuming alcohol while taking Bunase 0.5mg Respules 2ml is not known. Kindly consult your doctor before taking it.
Is it safe to drive while on this medicine?No interaction was established or found.
Does this affect kidney function?No interaction was established or found.
Does this affect liver function?No interaction was established or found.
Below is the list of medicines, which have the same composition, strength and form as Bunase 0.5mg Respules 2ml , and hence can be used as its substitute.
Missed Dose instructionsIf you miss a dose of Bunase 0.5mg Respules 2ml, take the missed dose as soon as you remember. If itâ€™s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose instructionsSeek emergency medical treatment or contact the doctor in case of an overdose.
This medicine inhibits the cells and mediators release of various types including eosinophils, eicosanoids, mast cells, histamine, neutrophils, leukotrienes, macrophages, lymphocytes, and cytokines. These cells and mediators are responsible for inflammation caused. Thus the medicine aids in treating allergic disorders as well as reduces inflammation.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
ClarithromycinThese medicines are not recommended together due to increase in the concentration of Bunase 0.5mg Respules 2ml. Inform the doctor if you have any symptoms like swelling, weight gain, high blood pressure, high blood glucose, and muscle weakness. An alternate medicine should be considered based on the clinical condition.
KetoconazoleThese medicines are not recommended together due to increase in the concentration of Bunase 0.5mg Respules 2ml. Inform the doctor if you have any symptoms like swelling, weight gain, high blood pressure, high blood glucose, and muscle weakness. An alternate medicine should be considered based on the clinical condition.
AntihypertensivesUse with caution as this combination will decrease the effect of antihypertensives. This interaction is more likely to occur if this medicine is taken for more than a week. Inform the doctor if you are taking either of the medicines. Dose adjustments are to be made based on the clinical condition.
Nonsteroidal anti-inflammatory drugsUse with caution as this combination will increase the risk of gastrointestinal bleeding. Inform the doctor if you are taking either of the medicines. Consider taking alternative medicine after consulting your doctor.
Interaction with Food
Interaction with Disease
- Controlled clinical studies have shown that inhaled and intranasal corticosteroids may cause a reduction in growth velocity in pediatric patients. Growth velocity provides a means of comparing the rate of growth among children of the same age.
- FDA's Pulmonary and Allergy Drugs and Metabolic and Endocrine Drugs advisory committees discussed this issue at a July 1998 meeting. They recommended that the agency develop class-wide labeling to inform healthcare providers so they would understand this potential side effect and monitor growth routinely in pediatric patients who are treated with inhaled corticosteroids, intranasal corticosteroids or both.
- Long-term effects of this reduction in growth velocity on final adult height are unknown. Likewise, it also has not yet been determined whether patients' growth will "catch up" if treatment in discontinued. Drug manufacturers will continue to monitor these drugs to learn more about long-term effects. Children are prescribed inhaled corticosteroids to treat asthma. Intranasal corticosteroids are generally used to prevent and treat allergy-related nasal symptoms.
- Patients are advised not to stop using their inhaled or intranasal corticosteroids without first speaking to their healthcare providers about the benefits of these drugs compared to their risks.
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