I'm a 20 years old male. My weight is around 65 kg i'm having treatment for rr tb from the past 2 months. In my treatment i'm having daily dosages of kanamycin injection (except sunday) and antibiotics medicines (dots). I just want to know how much time do these medicines take to absorb in the body. Actually most of the time except some days I usually vomit out 2-3 hours after taking medicines. Sometimes within 1 hour or 30 minutes. I don't have any difficulty in breathing or anything nor I feel any weakness anything but a feeling of nausea persists. And from last some days I feel upset stomach more and vomits 2-3 times a day. I just want to know is it normal? Do I have to take medicines again if I vomited after 1-2 hours? What can be done to prevent it. How can I recover early. Also is the treatment right? For how much duration kanamycin injection are injected. In my case they have prescribed for 4 months.

Dr. C. E PrasadPulmonologist34yrs exp

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Drug resistant tb is to be treated under regular supervision or review by the specialist in tb it's a national programme to prevent emergence of extreme resistance the standard practice has been to give one injectable additional drug and at least 7drugs from various special anti tb drugs. Kanamycin for resistant tb was prescribed for as long as 6 months with regular review by clinician for neuro and kidney adverse effects. Latestguidelines do not recommend injectables even for drug resistant tb as a policy except in special tb cases. All these drugs are known to cause git side effects simple drugs such as gelusilantacid or ranitidine or ondensetron when taken an hour before or an hour after anti tb drugs are helpful.  

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Dr. Rajesh JainEndocrinologist24yrs exp

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I think your treatment is Good but ckeck for S creatinine and blood urea after 4 weeks regulary... good luck 

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Dr. Dipankar PalPulmonologist13yrs exp

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Drug resistant tb needs prolonged treatment sometimes upto 18-24 months. Kanamycin is used for 4-9 months depending upon your condition. Vomitting and gastric upset is very common with mdr tb treatment at the initial few months. If you vomit after one hour then nothing is needed. If within one hour then may have to repeat. Your treating physician will guide you further.  

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