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Tuberculosis Health Feed

HIV & Tuberculosis - Is There A Link?

Dr. Lt Col Adnan Masood 89% (622 ratings)
MD - Internal Medicine, MBBS, Nephrology
General Physician, Roorkee
HIV & Tuberculosis - Is There A Link?

HIV and tuberculosis (TB) are two life-threatening and common diseases in the world. The two diseases are very closely connected so much so that their occurrence is normally labelled as a co-epidemic. In most cases tuberculosis is found to be the most transmissible contagion in HIV-Immunocompromised victims, proving to be the cause of their death.

What is HIV?
Human Immunodeficiency Virus, more commonly known by its abbreviation HIV, is a virus that attacks the immune system, which is the body's natural defense against illnesses. The virus terminates a kind of white blood cells (WBCs) in the immune system known as the T-helper cell also known as CD4 cells. This virus then proceeds to duplicate itself within these cells.

As HIV reduces the T-helper cells, by duplicating at an increasing rate, it slowly breaks down the patient’s immune system. This leaves the individual susceptible to other deadly diseases such as tuberculosis. HIV infection is a permanent disease with three phases of progression. HIV medications can reduce or stop the evolution of the disease from one phase to another. The treatment can also decrease the chances of spreading HIV to other people.

What is tuberculosis (TB)
Tuberculosis is a transmittable disease triggered by the presence of bacterium known as Mycobacterium tuberculosis. It is still considered a deadly disease in most developing countries where treatment is scarce. Generally, TB affects the lungs but it can also affect other parts of the body. Symptoms include – coughing with blood, fever, night sweats and loss of weight.

The relation between TB and HIV
In second world countries, most patients infected with HIV suffer from TB as the initial indicator of AIDS. Tuberculosis can occur at any phase of the HIV infection. The danger and severity of tuberculosis rises rapidly after infection with HIV. Even though tuberculosis can be a fairly primary indicator of HIV infection, it is imperative to observe that the risk of tuberculosis increases as the CD4 cell count reduces along with the progression of the HIV infection.

Treatment
Positive treatment for TB usually entails 6 months of rigorous therapy. HIV patients with TB usually respond well to this therapy, if the regimen comprises INH and a rifamycin for the period of TB therapy and cure. TB generally reappears when the immune system is unable to respond to stop the development of mycobacteria. The cytokine IFN-γ plays a key role in the response of the immune system all through the contagion.
HIV and TB infections area two-directional communication of the two pathogens. TB is one of the main causes of disease and fatality among patients with HIV in Africa and other severely affected regions. With almost a 50% kill rate around the world, raising awareness about this disease and consulting doctors when signs or symptoms appear is vital in reducing the extent of this epidemic.

Rifampicin- HIV treatment are complicated by the fact that one of the key drugs used in TB treatment, rifampicin, reduces blood levels of nevirapine (Viramune) by 30 to 55% and also reduces levels of most protease inhibitors.

1 person found this helpful

My son is 10 yes old, we following a doctor. He is on medication, taking akurit 150/75. He has been taking for 2 months, we are unable to contact the doctor. Due to lighten we can't visit the doctor. As review date is 3/04/2020. Pls help me what to do? Should I continue with the same medicine or something else?

Dr. Prakhar Singh 92% (3715 ratings)
MBBS, Basic Life Support (B.L.S), Advanced Cardiac Life Support, Fellow of Academy of General Education (FAGE)
General Physician, Delhi
My son is 10 yes old, we following a doctor. He is on medication, taking akurit 150/75. He has been taking for 2 mont...
Thank you for connecting with me e, I am happy to guide you on your concern .akurit 150/75 mg is a medications used in both pulmonary and extrapulmonary tb in the intensive initial phase of treatment. Follow the proper line of treatment as per recommendation and do not discontinue on its own. Let's get connected over call to discuss proper treatment options for you.
1 person found this helpful
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I need to take tele consultancy from a pulmonary and tb doctor for my father in law.

Dr. Prakhar Singh 92% (3715 ratings)
MBBS, Basic Life Support (B.L.S), Advanced Cardiac Life Support, Fellow of Academy of General Education (FAGE)
General Physician, Delhi
Thank you for connecting with me, I am happy to guide you on your concern. Pulmonary tuberculosis can lead to coughing that lasts three or more weeks, coughing up blood, fatigue, fever, night sweats - etc let's get connected over a call to discuss proper treatment options for you.
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मुझे फेफड़ों का टीवी हुआ है मुझे akurit-4. 6 tablet लेने को कहा है यह टेबलेट मुझे कितने दिन लेनी है क्या यहां टीवी की बीमारी की बेस्ट टेबलेट है

Dr. Manjit Tendolkar 90% (10 ratings)
MBBS, MD - Pulmonary Medicine
Pulmonologist, Navi Mumbai
मुझे फेफड़ों का टीवी हुआ है मुझे akurit-4. 6 tablet लेने को कहा है यह टेबलेट मुझे कितने दिन लेनी है क्या यहां टीवी की...
Greetings lybrate-user, akurit-4 for 2 months followed by akurit -3 for 4 months is the recommended regimen for drug sensitive pulmonary tuberculosis. Total course of 06 months.
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I have met my friend who's suffering from tb when met none of us are aware of the condition she stayed in same room what is the probability of me getting effected with it? We both slept on the same bed as well I have seen her coughing multiple times.

Dr. S.K. Tandon 96% (46042 ratings)
M.D. Consultant Pathologist, CCEBDM Diabetes, PGDS Sexology USA, CCMTD Thyroid, ACDMC Heart Disease, CCMH Hypertension, ECG, CCCS ( CARDIOLOGY & STROKE)
Sexologist, Sri Ganganagar
Better go for check and follow up. This way tb spreads. Take same precautions as in corona are being advised.
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Hey sir I am 21 year old I have tuberculosis since 1 year almost. First it affect my lungs and then it affect my abdomen, lungs are recovered and abdominal tuberculosis is recovering. I want to know the risk of corona virus on me. Please help.

Dr. Pulak Mukherjee 92% (9579 ratings)
BHMS
Homeopathy Doctor, Hooghly
Well yes people having this type of disease is very much vulnerable to corona virus, soo be safe, don't go out, stay at home, visit your doctor if you feel any resp difficult with fever and sore throat,
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My brother suffering from fever and dry cough headache and hip pain. In first 10 days he take medicine it's not cure. And then doctor said me take chest xray but we r affect in symptoms of typhoid then why doctor said me chest xray. I changed hospital then going to another hospital we r telling to that doctor my symptoms is typhoid. That doctor said me to take blood test that blood test says typhoid. He under medication at 15 days to same doctor. That doctor is madam she is ask me to go for senior doctors to the same hospital. That senior doctor after listening to my symptoms he advised me to take chest xray then I can do that that xray says left side lungs full of pleural fluid. Then that doctor take back side of my brother 2000 ml pleural fluid in two sittings that doctor said me this is tuberculosis take medicine with one year the medicine name is forecox 150 mg omnacortil 10 mg macfast 650 mg taxim 0 200 mg. 3 days after discharge I take medicine 3 tablets forecox omnacortil macfast in last 5 days fever not came he is well now. Pls clear my doubt this is for tuberculosis or not I take medicine for one years or not tb stage how much this is how to conform this is tb give me. Advise what can I do. If the tb patient follow medicine with govt hospital or private hospital which one is best. That doctor come to review after 15 days what can I do my brother age is 22. This is curable. Or not i'm very feelings about my brother future now brother weight is 59.

Dr. Bhupindera Jaswant Singh 88% (4684 ratings)
MD - Consultant Physician, Doctor of Medicine, MD, Phd korea
General Physician, Ahmedabad
My brother suffering from fever and dry cough headache and hip pain. In first 10 days he take medicine it's not cure....
This is clear cut case of tubercular pleural effusion as chief presentation put on tapering steroids and take akt 4 for 2 months and akt 3 for 3 months more high protein diet veg fruits sputum for afb x 3 pcr for tb montoux test .
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My daughter is 4 years old and suffer from bronchial asthma. She is currently using duolin for her nebulizer. The problem is whenever she plays, she will suffer from breathing the weather can change from she will be having a breathing problem. Her doctor said she must use seroflo 25/50 inhaler and astravent. I'm scared will it not at a later stage give my baby lung problems or infection. I need advice. Is there maybe anything else that I can use. Please help.

Dr. Avya Bansal 88% (91 ratings)
MBBS, MD (Respiratory Medicine), DNB (Respiratory diseases)
Pulmonologist, Mumbai
My daughter is 4 years old and suffer from bronchial asthma. She is currently using duolin for her nebulizer. The pro...
The only treatment for asthma is inhalers like we don't worry about heart and diabetes medication, similarly asthma inhalers are very very important. They are safe, no side effects if taken correctly and especially in such age groups there's complete resolution. Please don't worry, give your child inhalers and regularly follow up with a chest physician or paediatrician.
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I have got a scoliosis in the spine. Doctor has a low suspicion of tb. Told me to do cbc esr and crp tests which package should I take?

Dr. Shobhit Tandon 96% (2893 ratings)
MBBS, PG-Diploma In Clinical Pathology
Sexologist, Sri Ganganagar
I have got a scoliosis in the spine. Doctor has a low suspicion of tb. Told me to do cbc esr and crp tests which pack...
Dear get it done individual only also get tb quantiferon gold test too. It will be conclusive then.
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