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Overview

Repace 25 MG Tablet

Repace 25 MG Tablet

Manufacturer: Sun Pharma Laboratories Ltd
Medicine composition: Losartan
Prescription vs.OTC: Prescription by Doctor required

Repace 25 MG Tablet belongs to the angiotensin II receptor antagonists group of drugs. It prevents the blood vessels in your body from narrowing, thus lowering your blood pressure and improving the blood circulation. This medication has the ability to lower the possible risk of a stroke in people suffering from any heart condition. Apart from that, it can also slow down kidney damage among people with type 2 diabetes. You can take this medicine with as well as without food. It can take 3-6 weeks for your blood pressure to come under control after you have started a course of this medication.

Repace 25 MG Tablet is a prescription drug that is available in the form of an oral tablet. There are three main reasons for its usage. Firstly, it is used for the treatment of high blood pressure. The second usage is for reducing the risk of stroke in people, who already have high blood pressure as well as left ventricular hypertrophy (LVH). LVH is a condition where the left ventricle (chamber) of the heart thickens as a result of which the heart is unable to pump well. Lastly, Repace 25 MG Tablet is used for treating diabetic nephropathy, a kidney disease caused due to diabetes.

Repace 25 MG Tablet blocks the action of the chemical named angiotension II in the body, which causes the blood vessels to narrow and tighten. This medication helps the blood vessels to relax and eventually widen. It lowers your blood pressure, thus reducing your risk of having a stroke or kidney damage.

The dosage and the form of having Repace 25 MG Tablet depends on your age, severity of your condition, your medical history and also how your body reacts when you take the first dose. If you miss a dose, take it once you realize the missed dose. However, ensure that you do not take two doses at the same time just because you missed the previous one. Overdosing can make you feel dizzy, weak or a pounding heart.

There are some common side effects of Repace 25 MG Tablet that are generally mild and go away in a few days. They include:

  • Stuffy nose
  • Back pain
  • Diarrhea
  • Fatigue and dizziness
  • Pain in the chest
  • High/low blood pressure

There are some serious side effects too for consuming Repace 25 MG Tablet. In case you experience any of the following symptoms, you must consult the doctor immediately and seek medical help:

  • If you experience problems in your heart rhythms, a slow heart rate or weakness in the muscles. It could be an indication of high potassium levels in your blood.
  • Symptoms of swelling in the tongue, throat, lips or face; indicating an allergic reaction.
  • Swelling in the ankles, feet, hand or sudden weight gain can be a sign of kidney problem. In case you are suffering from a kidney problem or disease, Repace 25 MG Tablet may worsen the condition.
type diabetes
Repace 25 MG Tablet is used in the treatment of Hypertension which is an increase in the blood pressure caused by genetic and environmental factors.
Diabetic Nephropathy
Repace 25 MG Tablet is used in the treatment of diabetic Nephropathy which is a type of kidney disease which occurs due to high blood glucose.
Avoid if you have a known allergy to Repace 25 MG Tablet or any medicine of the same class.
Aliskiren
Use of these medicines is not recommended in the elderly population with diabetes and kidney disease with CrCl less than 60 ml/min.
In addition to its intended effect, Repace 25 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.
Stomach pain Major Common
Chills Major Common
Difficulty or painful urination Major Common
Fast heartbeat Major Common
Back pain Major Common
Chest tightness Major Rare
Dizziness Major Rare
Weakness in arms, hands, legs or feet Major Rare
Nasal congestion Minor Common
Sore throat Minor Common
Acid or sour stomach Minor Less Common
Heartburn Minor Less Common
How long is the duration of effect?
This medicine is excreted largely in faeces and the effect lasts for a duration of approximately 24 hours.
What is the onset of action?
The peak effect of this medicine can be observed in 1 to 1.5 hours.
Are there any pregnancy warnings?
This medicine is not recommended for pregnant women.
Is it habit forming?
No habit forming tendency has been reported.
Are there any breast-feeding warnings?
This medicine is not recommended for women who are breastfeeding.
Below is the list of medicines, which have the same composition, strength and form as Repace 25 MG Tablet, and hence can be used as its substitute.
Orchid Chemicals & Pharmaceuticals Ltd
Torrent Pharmaceuticals Ltd
Ranbaxy Laboratories Ltd
Cadila Pharmaceuticals Ltd
Are there any missed dose instructions?
The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
Are there any overdose instructions?
Seek emergency medical treatment or contact the doctor in case of overdose.
India
United States
Japan
Whenever you take more than one medicine, or mix it with certain foods or beverages, you're at risk of a drug interaction.
Interaction with Disease
Congestive heart failure Moderate
Repace 25 MG Tablet is used with caution in patients with congestive heart failure especially in volume or sodium depletion. Transient hypotension is also not a contraindication to further treatment with AR antagonists, since therapy can usually be reinstated without difficulty after blood pressure stabilizes.
Interaction with Alcohol
Alcohol Moderate
Consumption of alcohol with this medicine will lower the blood pressure and can cause dizziness, headache, changes in heart rate. Avoid driving or operating heavy machinery if you have these symptoms.
Interaction with Lab Test
Lab
Information not available.
Interaction with Food
Food
Information not available.
Interaction with Medicine
Aliskiren Major
Use of these medicines is not recommended especially in the elderly population with diabetes and kidney disease with CrCl less than 60 ml/min. You experience weakness, confusion, and irregular heartbeat if these medicines are taken together. Regular monitoring of blood pressure and kidney function tests are to be performed. An alternate medicine should be considered under the doctor's supervision.
Captopril Major
Use of these medicines is not recommended as it may increase the risk of kidney impairment and low blood pressure. You may experience weakness, confusion, and irregular heartbeat if these medicines are taken together. Regular monitoring of blood pressure and kidney function tests are to be performed. An alternate medicine should be considered under the doctor's supervision.
Dexamethasone Moderate
The desired effect of Repace 25 MG Tablet will not obtain if these medicines are taken together. This interaction is more likely to happen if dexamethasone is taken for more than 1 week. Inform the doctor if you have a sudden weight gain, swelling of hands and feet. If coadministration is needed then appropriate dose adjustments are to be made under the doctor's supervision. Regular monitoring of blood pressure and kidney function tests are to be performed.
Diclofenac Moderate
The desired effect of Repace 25 MG Tablet will not obtain if these medicines are taken together. The risk of kidney impairment will increase if these medicines are taken together especially in elderly population or having pre-existing kidney disease. Inform the doctor if you have an increased or decreased urination and unexplained weight gain or weight loss. Regular monitoring of blood pressure and kidney function tests are to be performed.
Insulin Moderate
The effect of insulin will increase if these medicines are taken together. You may experience dizziness, headache, sweating if these medicines are taken together. Regular monitoring of blood glucose levels is needed. Suitable dose adjustments or an alternate medicine should be considered under the doctor's supervision.

Popular Questions & Answers

Hi .My bp is always 90- 130, I take repace 50 since 2 yr, but my bp remain constant. Can I change the medicine.

MBBS, MD - Internal Medicine, DM - Cardiology, Cardiac Device Specialist (CCDS - Physician )
Cardiologist, Delhi
Hi .My bp is always 90- 130, I take repace 50 since 2 yr, but my bp remain constant. Can I change the medicine.
Your BP is within normal range and it is probably due to the medicine repace. Since the medication is so effectively controlling your BP there is no sense in changing it unless you are experiencing any side effects. Instead of changing medications, it will be better if you add lifestyle changes as well in your life like - 1) daily exercise for 30-40 mins, 2) eating a healthy diet including fruits and fibres (for detailed diet plan please consult a dietician 3) salt control in diet by avoiding high salty food like pickles, chutneys, papads, namkleens, sauces etc 4) quitting smoking and alcohol 3) limiting caffeine intake to 1-2 cups in a day 4) reducing stress and anxiety.
1 person found this helpful

I am 41 years of age. Last 6 years I have taken medicine for B.P problem Repace 50 mg. Regularly ,& you know my blood report so then your suggestions for this matter? 2. Depending report I want to know I have kidney problem?

BHMS
Homeopath, Chennai
I am 41 years of age. Last 6 years I have taken medicine for B.P problem Repace 50 mg. Regularly ,& you know my blood...
Raised blood pressure is not a disease in itself. It is just a sign of some underlying disorder. Homeopathy offers good prognosis for cases of essential hypertension. The treatment is based upon the cause and the totality of the case. A constitutional homoeopathic treatment will cure you permanently. You can easily take an online consultation for further treatment guidance
1 person found this helpful

Sir my father have swelling in lower leg from last 10 Days. They have 6.86 point uric acid. They have taken Cilacar for Blood pressure from last 15 days. Previously they taken repace h for Blood pressure. They do not have any problem like diabetes or other. Please suggest me best treatment for them. Thanks,

MBBS
General Physician, Cuttack
Sir my father have swelling in lower leg from last 10 Days. They have 6.86 point uric acid. They have taken Cilacar f...
His uric acid is slightly high 1. Avoid protein rich diets like mutton, egg, fish, sea food (sardines)/prawn 2.Avoid pulses, lentill, mushrooms, green leafy vegetablles like broccoli, cauli flower, cabbage, spinach, beans, peas 3. Take fruits like apple, banana, orange, black cherry, lime etc 4. Drink plenty of water (8-10 glass) daily 5. Avoid alcohol and caffeinated drinks, excess sweets cakes/cookies 6.Reduce weight if overweight 7. Take medicine after consulting physician.

My bp is 160 /103. Pulse 103. Sugar 111. I take Repace 50 tabs one twice daily. Please help as bp and pulse not reducing Tx.

MBBS
General Physician, Mumbai
My bp is 160 /103. Pulse 103. Sugar 111. I take Repace 50 tabs one twice daily. Please help as bp and pulse not reduc...
Dear Lybrateuser, - If you reduce your weight by diet & exercise then your BP will proportionately reduce by few points - have more of fibrous foods, fruits, vegetables including green leafy ones, whole grains, legumes, lentils, low fat dairy, lean meats, nuts - avoid fried, processed & junk foods, restrict intake of salt, also restrict intake of tea, coffee to 1-2 cups per day - do regular exercise walking for 30-40 min, also do yoga, meditation & deep breathing for 10-15 min daily morning - take medication on time as prescribed & get BP measured regularly.
1 person found this helpful

My bp continues to be 166/93. I take Repace 50 tabs. One tab twice daily. But no improvement. Please help. My sugar is 96.

MBBS
General Physician, Mumbai
My bp continues to be 166/93. I take Repace 50 tabs. One tab twice daily. But no improvement. Please help. My sugar i...
Dear Lybrateuser, - You have to reduce your weight so that the BP also will come down a few points - restrict your salt & sugar intake, avoid fried, processed & junk food, foods containing saturated & trans fats, restrict intake of tea, coffee to 1-2 cups - have more of fibrous foods, fruits, vegetables, whole grains, legumes, sprouts, a handful of nuts - use healthy fats like in olive, canola oil, walnuts, avocados & fish - do regular exercise like walking for 30 min, also do yoga, deep breathing & meditation for 10-15 min in the morning - take BP regularly as advised by your doctor - consult your cardiologist as the dose of the drug or the drug may be required to be changed.

Popular Health Tips

Chronic Nephritis - How To Cope With It?

DNB (Nephrology), MD, MBBS
Nephrologist, Delhi
Chronic Nephritis - How To Cope With It?

Chronic nephritis is a type of Glomerulonephritis (GN). In this condition, irritation takes place in the Glomeruli, which are parts in your kidneys comprising tiny blood vessels. These knots of vessels filter your blood and remove excess fluids from the body. In case your glomeruli are harmed, your kidneys will quit working properly and you can suffer from kidney failure. It is a very serious illness that can be life threatening and requires immediate medical intervention.

The condition is also called nephritis. There can be both acute and chronic nephritis. The chronic type of GN can take several years to develop with almost no obvious symptoms. This can cause irreversible harm to your kidneys and also prompt complete kidney failure.

Causes and risks:
A hereditary condition can once in a while cause chronic nephritis. It happens in young men with poor vision and poor hearing. Persistent and untreated conditions may also bring about chronic nephritis. A history of cancer in the family may likewise put you at danger. Having acute nephritis may make you more prone to build up chronic nephritis later on. Being exposed to some hydrocarbon solvents may build the danger of chronic nephritis. Chronic nephritis does not generally have a clear-cut cause. About 25% of individuals with this condition have no history of kidney diseases.

Symptoms:
A few symptoms of chronic nephritis include:

  1. Blood or abundance protein in your urine
  2. Hypertension
  3. Swelling in lower legs
  4. Continuous urination during evenings
  5. Bubbly or frothy urine (from abundance protein)
  6. Stomach pain
  7. Continuous nosebleeds


Treatment:
Depending upon the symptoms of the problem, the treatment might be distinctive. Some of the ways it can be dealt with are:

  • Controlling hypertension, particularly if that is the hidden cause for the problem. Circulatory strain might be difficult to control when your kidneys are not working properly. If so, your specialist may prescribe pulse medicines, including angiotensin-changing over catalyst inhibitors. Some of these medicines include Captopril, Lisinopril and Perindopril.
  • Your specialist may likewise recommend angiotensin receptor blockers (ARBs). Some of these may include Losartan, Irbesartan and Valsartan.
  • Another technique to reduce immune-triggered aggravation is plasmapheresis. This procedure expels the liquid part of the blood (plasma) and replaces it with intravenous (IV) liquids or donated plasma (without any antibodies).

For chronic GN, you will have to decrease the level of protein, salt and potassium in your diet. Also, you should observe the amount of fluid you drink. Calcium supplements might be suggested and you may need to take diuretics to lessen swelling. Not surprisingly, check with your general physician or kidney specialist for rules about dietary restrictions or food. In case your condition worsens and causes kidney failure, you may need dialysis. This is a technique where a machine filters your blood. In the end, you may require a kidney transplant. If you wish to discuss about any specific problem, you can consult a Nephrologist.

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