Losartan belongs to the angiotensin II receptor antagonists group of drugs. It prevents the blood vessels in your body from narrowing, thus lowering your blood pressure and improving the blood circulation. This medication has the ability to lower the possible risk of a stroke in people suffering from any heart condition. Apart from that, it can also slow down kidney damage among people with type 2 diabetes. You can take this medicine with as well as without food. It can take 3-6 weeks for your blood pressure to come under control after you have started a course of this medication.
Losartan is a prescription drug that is available in the form of an oral tablet. There are three main reasons for its usage. Firstly, it is used for the treatment of high blood pressure. The second usage is for reducing the risk of stroke in people, who already have high blood pressure as well as left ventricular hypertrophy (LVH). LVH is a condition where the left ventricle (chamber) of the heart thickens as a result of which the heart is unable to pump well. Lastly, Losartan is used for treating diabetic nephropathy, a kidney disease caused due to diabetes.
Losartan blocks the action of the chemical named angiotension II in the body, which causes the blood vessels to narrow and tighten. This medication helps the blood vessels to relax and eventually widen. It lowers your blood pressure, thus reducing your risk of having a stroke or kidney damage.
The dosage and the form of having Losartan depends on your age, severity of your condition, your medical history and also how your body reacts when you take the first dose. If you miss a dose, take it once you realize the missed dose. However, ensure that you do not take two doses at the same time just because you missed the previous one. Overdosing can make you feel dizzy, weak or a pounding heart.
There are some common side effects of Losartan that are generally mild and go away in a few days. They include:
There are some serious side effects too for consuming Losartan. In case you experience any of the following symptoms, you must consult the doctor immediately and seek medical help:
- If you experience problems in your heart rhythms, a slow heart rate or weakness in the muscles. It could be an indication of high potassium levels in your blood.
- Symptoms of swelling in the tongue, throat, lips or face; indicating an allergic reaction.
- Swelling in the ankles, feet, hand or sudden weight gain can be a sign of kidney problem. In case you are suffering from a kidney problem or disease, Losartan may worsen the condition.
Diabetic NephropathyLosartan is used in the treatment of diabetic Nephropathy which is a type of kidney disease which occurs due to high blood glucose.
AliskirenUse of these medicines is not recommended in the elderly population with diabetes and kidney disease with CrCl less than 60 ml/min.
How long is the duration of effect?This medicine is excreted largely in faeces and the effect lasts for a duration of approximately 24 hours.
What is the onset of action?The peak effect of this medicine can be observed in 1 to 1.5 hours.
Are there any pregnancy warnings?This medicine is not recommended for pregnant women.
Is it habit forming?No habit forming tendency has been reported.
Are there any breast-feeding warnings?This medicine is not recommended for women who are breastfeeding.
Are there any missed dose instructions?The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
Are there any overdose instructions?Seek emergency medical treatment or contact the doctor in case of overdose.
Below is the list of medicines, which contains Losartan as ingredient
This medicine works by displacing angiotensin II with very high affinity from its binding site at the AT1 receptor subtype, which is responsible for the known actions of angiotensin II.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
AlcoholConsumption of alcohol with this medicine will lower the blood pressure and can cause dizziness, headache, changes in heart rate. Avoid driving or operating heavy machinery if you have these symptoms.
Interaction with Lab Test
LabInformation not available.
Interaction with Medicine
AliskirenUse of these medicines is not recommended especially in the elderly population with diabetes and kidney disease with CrCl less than 60 ml/min. You experience weakness, confusion, and irregular heartbeat if these medicines are taken together. Regular monitoring of blood pressure and kidney function tests are to be performed. An alternate medicine should be considered under the doctor's supervision.
CaptoprilUse of these medicines is not recommended as it may increase the risk of kidney impairment and low blood pressure. You may experience weakness, confusion, and irregular heartbeat if these medicines are taken together. Regular monitoring of blood pressure and kidney function tests are to be performed. An alternate medicine should be considered under the doctor's supervision.
DexamethasoneThe desired effect of Losartan will not obtain if these medicines are taken together. This interaction is more likely to happen if dexamethasone is taken for more than 1 week. Inform the doctor if you have a sudden weight gain, swelling of hands and feet. If coadministration is needed then appropriate dose adjustments are to be made under the doctor's supervision. Regular monitoring of blood pressure and kidney function tests are to be performed.
DiclofenacThe desired effect of Losartan will not obtain if these medicines are taken together. The risk of kidney impairment will increase if these medicines are taken together especially in elderly population or having pre-existing kidney disease. Inform the doctor if you have an increased or decreased urination and unexplained weight gain or weight loss. Regular monitoring of blood pressure and kidney function tests are to be performed.
InsulinThe effect of insulin will increase if these medicines are taken together. You may experience dizziness, headache, sweating if these medicines are taken together. Regular monitoring of blood glucose levels is needed. Suitable dose adjustments or an alternate medicine should be considered under the doctor's supervision.
Interaction with Disease
Congestive Heart FailureLosartan is used with caution in patients with congestive heart failure especially in volume or sodium depletion. Transient hypotension is also not a contraindication to further treatment with AR antagonists, since therapy can usually be reinstated without difficulty after blood pressure stabilizes.
Interaction with Food
FoodInformation not available.
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