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Paxotus 25 MG Tablet

Manufacturer: Emcure Pharmaceuticals Ltd
Medicine composition: Paroxetine
Prescription vs.OTC: Prescription by Doctor required
Last Updated: December 14, 2018

Paxotus 25 MG Tablet is an antidepressant that is used in the treatment of various mental disorders such as OCD, depression, anxiety, post-traumatic stress disorder (PTSD). The Brisdelle brand of Paxotus 25 MG Tablet is used in the treatment of hot flashes and night sweats that comes from menopause. It is sold under the trade names Paxil and Seroxat.

On using Paxotus 25 MG Tablet the common side effects that you may experience are dryness of the mouth, reduced appetite, drowsiness, insomnia, problems with ejaculation, agitation, chest pain, skin rash, difficulty in breathing, lightheadedness, dizziness, fast or irregular heartbeat, fever, restlessness, speech problems, blurred vision, acidity, abdominal pain, cough, darkening of the urine and shakiness. Notify your doctor immediately if you have suicidal thoughts, hallucinations, coordination issues and convulsion. Before using this medicine, tell your doctor if you have any of the following conditions:

  • If you are pregnant, or are planning to become pregnant, or are breastfeeding a baby.
  • If you have low sodium levels.
  • If you have a history of seizures or epilepsy.
  • If you have a history of glaucoma.
  • If you have liver, heart or kidney diseases.
  • If you are taking any prescriptive or over the counter drugs, herbal medications or dietary supplements. As interaction with certain drugs especially anti-inflammatory ones such as NSAID may cause certain harmful reactions.

The dosage for Paxotus 25 MG Tablet will be prescribed by your doctor as per your medical history, age, gender, the current medical condition and what reactions you have after the first course of medicine. Paxotus 25 MG Tablet is available in both tablet and liquid form. Generally the usual dose in adults is about 20 mg (tablet/suspension) orally once in a day.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Psychiatrist before using this medicine.

This medicine is used for the treatment of acute episodes of depression associated with chemical imbalance in the brain.

Social Anxiety Disorder

This medicine is used for the treatment of a mental condition characterized by an abnormal fear during normal social situations.

Panic disorder

This medicine is used for the treatment of panic disorder and associated symptoms like overwhelming anxiety and fear coupled with increased heart rate, trembling, numbness and tingling sensation.
This medicine is used to treat depression, tension, and irritability occurring 5-11 days before the start of a menstrual cycle.

Obsessive Compulsive Disorder

This medicine is used for the treatment of a disorder where a person is driven to do compulsive tasks caused by obsessive thoughts.
This medicine is used for the treatment of anxiety, sleeplessness and other behavioral changes after experiencing or witnessing a terrifying event.

Generalized anxiety disorder

This medicine is used for the treatment of general anxiety caused due to excessive thinking about life, work, relationships etc.

Postmenopausal symptoms

This medicine is used to treat symptoms like anxiety, mood swings, fear etc associated with menopause in women.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use while a MAOI medicine (Rasagiline/Selegiline/methylene blue etc.) is being consumed. This medicine should be consumed at least 14 days after stopping the use of MAOI medicines.

Thioridazine

This medicine is not recommended for use if the patient is taking Thioridazine (medicine used to treat schizophrenia).

Pimozide

This medicine is not recommended for use if the patient is taking Pimozide (anti psychotic medicine).
This medicine is not recommended for use if you a known history of allergy to Paxotus 25 MG Tablet or any other ingredient present with it.
In addition to its intended effect, Paxotus 25 MG Tablet may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Suicidal thinking and behaviour

Major Less Common

Serotonin syndrome (agitation, hallucinations, seizures, nausea)

Major Less Common

Irregular heartbeat

Major Rare

Shaking of the hands or feet

Major Less Common

Dizziness when getting up suddenly from a sitting position

Moderate Less Common

Chills or cold sweats

Major Rare

Blurred vision

Moderate Rare

Nausea and Vomiting

Moderate Common

Dry mouth and lips

Moderate Common

Constipation

Moderate Common

Muscle stiffness

Moderate Less Common

Decreased sexual urge

Moderate Less Common

Difficulty in passing urine

Moderate Common

Rapid weight gain/loss

Minor Less Common

Photosensitivity

Minor Less Common

Unusual bleeding or bruising

Moderate Less Common

Racing thoughts

Moderate Common

Reckless behavior

Moderate Rare

Unusual tiredness and weakness

Minor Less Common

How long is the duration of effect?

The time for which this medicine remains effective in the body is not clearly established. Dosing, duration and the condition for which this medicine is given determine the effective time duration.

What is the onset of action?

The effect of this medicine is cumulative and may take months to show. It varies depending on the intended use and the dosing.

Are there any pregnancy warnings?

Use of this medicine by pregnant women is not recommended as the risk of adverse effect on the fetus is very high. Consult your doctor if you are pregnant or are planning a pregnancy while taking this medicine.

Is it habit forming?

No habit forming tendencies were reported.

Are there any breast-feeding warnings?

Use of this medicine by breastfeeding women is not recommended unless necessary. If necessary, your doctor may advise you to stop breastfeeding before treatment with this medicine is initiated.
Below is the list of medicines, which have the same composition, strength and form as Paxotus 25 MG Tablet , and hence can be used as its substitute.
Alkem Laboratories Ltd
Micro Labs Ltd
Ipca Laboratories Pvt Ltd.
Mankind Pharmaceuticals Ltd

Missed Dose instructions

Take the missed dose as soon as you remember. If the next scheduled dose is less than 4 hours away, then the missed dose should be skipped.

Overdose instructions

Contact a doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include agitation, hallucinations, convulsions, nausea, drowsiness, fast or slow heartbeat, and convulsions.

India

United States

Japan

Paxotus 25 MG Tablet works by selectively inhibiting the reuptake of serotonin. This results in higher concentrations of serotonin in the brain.,
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Kidney Disease

Moderate
This medicine should be used with caution in patients with an impaired kidney function. Suitable dose adjustments should be made based on the serum creatinine levels for moderate to severe impairment.

Glaucoma

Moderate
This medicine should be used with caution in patients having narrow-angle glaucoma. The symptoms of the disease might worsen if this medicine is used in such patients.

Hypertension

Moderate
This medicine may cause an increase in the blood pressure levels and hence should be used with caution in patients with hypertension. The blood pressure level should be constantly monitored before and during the course of treatment.

Liver Disease

Moderate
This medicine should be used with caution in patients with an impaired liver function. Suitable dose adjustments should be made based on the severity of impairment.

Interaction with Alcohol

Ethanol

Moderate
Avoid or limit the uptake of alcohol while using this medicine. It is advised to refrain from driving vehicles and operating heavy machinery while using this medicine.

Interaction with Lab Test

Lab

Information not available.

Interaction with Food

Food

Information not available.

Interaction with Medicine

Linezolid

Major
Report the use of either of the medicines to the doctor. There must be a sufficient time gap between the use of these medicines. Your doctor may determine the best course of treatment after accessing the condition.

Lithium

Major
Report the use of either of the medicines to the doctor. The risk of adverse effects is significantly high when these medicines are used together. Your doctor may determine the best course of treatment after accessing the condition.

Ondansetron

Major
Report the use of either of the medicines to the doctor. The risk of adverse effects is significantly high when these medicines are used together. Your doctor may determine the best course of treatment after accessing the condition.

Sertraline

Major
Report the use of either of the medicines to the doctor. The risk of adverse effects is significantly high when these medicines are used together. Your doctor may determine the best course of treatment after accessing the condition.

Warfarin

Moderate
Report the use of Warfarin or other anticoagulants to the doctor before receiving paroxetine. The risk of adverse effects is significantly high in the elderly and patients with kidney or liver diseases. Your doctor may determine the best course of treatment after accessing the condition.

Aspirin

Moderate
Report the use of Aspirin or other NSAIDs to the doctor before receiving paroxetine. The risk of adverse effects is significantly high in the elderly and patients with kidney or liver diseases. Your doctor may determine the best course of treatment after accessing the condition.

Methylene blue

Major
Report the use of either of the medicines to the doctor. There must be a sufficient time gap between the use of these medicines. Your doctor may determine the best course of treatment after accessing the condition.

Indinavir

Major
Report the use of either of the medicine to the doctor. You may need a dose adjustment and more frequent clinical monitoring to safely use them together.

Sumatriptan

Moderate
Report the use of either of the medicines to the doctor. The risk of adverse effects is significantly high when these medicines are used together. Your doctor may determine the best course of treatment after accessing the condition.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Paxotus 25 MG Tablet
What are the uses of Paxotus 25 MG Tablet
What are the contraindications of Paxotus 25 MG Tablet ?
What are the side effects of Paxotus 25 MG Tablet ?
Key highlights of Paxotus 25 MG Tablet
What are the substitutes for Paxotus 25 MG Tablet ?
What are the dosage instructions?
Where is the Paxotus 25 MG Tablet approved?
How does medicine works?
What are the interactions of Paxotus 25 MG Tablet ?