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Fluoxetine

Prescription vs.OTC: Prescription by Doctor required

Fluoxetine is used for the treatment of obsessive-compulsive disorder (OCD), depression, sudden panic attacks, bulimia (eating disorder) and premenstrual dysphoric disorder (symptoms of tension, irritability and depression before menstruation). The medication can improve your sleep, mood, appetite as well as the energy level. It belongs to the drug group known as selective serotonin reuptake inhibitors (SSRIs). It works by increasing the serotonin amount in your body, which is a natural substance present in your brain that helps in maintaining mental balance.

Fluoxetine is available in the form of a tablet, capsule, delayed-release capsule and a liquid solution, to be taken orally. It can be taken with food or without it. The dosage will depend on your present health condition and how your body reacts to the first dose. Your doctor may prescribe a low dose initially and then increase it gradually. It is advised not to stop the medication abruptly without consulting your doctor, as there is a possibility of experiencing withdrawal symptoms such as mood changes, dizziness, anxiety, confusion, agitation or irritability. It may take 4-5 weeks and sometimes even longer for Fluoxetine to show its full effectiveness.

You can suffer from mild side effects like nervousness, nausea, dry mouth, weakness, drowsiness and decreased sexual performance while taking Fluoxetine. You can consult your doctor if they refuse to go away after some time. However, there can be some serious side effects too in some cases that require immediate medical attention:

Fluoxetine can make you feel drowsy or dizzy. It is advised not to drive or do any other activity that requires your complete concentration. In case you are an elderly patient, be careful when you are getting up from a sitting or sleeping position to avoid a sudden fall. Also, you must avoid alcohol while you are under this medication.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a Psychiatrist before using this medicine.

Fluoxetine is used in the treatment of Bulimia which is an excessive eating disorder caused by genetic and psychological factors. Some of the symptoms include living in fear of gaining weight and eating continuously until it feels uncomfortable.
Fluoxetine is used in the treatment of depression which is a serious mood disorder caused by genetic and environmental factors. Feeling sad, irritable and devoid of energy are some the symptoms of depression.

Obsessive Compulsive Disorder

Fluoxetine is used in the treatment of obsessive-compulsive disorder which is an anxiety disorder caused by genetic and environmental factors. Some of the symptoms include aggression, suffering from a fear of contamination, and getting an obsessive urge to clean.

Panic disorder

Fluoxetine is used in the treatment of the panic disorder. Sweating, breathing problem, weakness and numbness in hands are some of the symptoms of panic disorder.
Fluoxetine is used in the treatment of premenstrual dysphoric disorder which is a condition in which women has irritability, tension, and depression before menstruation.
If you have a known allergy to Fluoxetine or any other medicines belongs to the class selective serotonin reuptake inhibitors.

Monoamine oxidase inhibitors

Fluoxetine is not recommended in patients who have taken Monoamine oxidase inhibitors within the last 14 days.
In addition to its intended effect, Fluoxetine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Skin rash

Major Common

Restlessness

Major Common

Fever or chills

Major Less Common

Muscle or joint pain

Major Less Common

Anxiety

Major Rare

Increased sweating

Major Rare

Dry mouth

Major Rare

Decreased appetite

Minor Common

Abnormal dreams

Minor Less Common

Frequent urination

Minor Less Common

Changes in vision

Minor Less Common

Convulsions (seizures)

Major Rare

How long is the duration of effect?

The effect of this medicine lasts for an average duration of 12 to 14 days.

What is the onset of action?

The peak effect of this medicine can be observed in 6 to 8 hours.

Are there any pregnancy warnings?

This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine.

Is it habit forming?

No habit forming tendency has been reported

Are there any breast-feeding warnings?

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine. Monitoring of undesired effects like colic, fussiness, and drowsiness is necessary.

Missed Dose instructions

Take the missed dose as soon as you remember. If its almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose instructions

Seek emergency medical treatment or contact the doctor in case of an overdose.

India

United States

Japan

Below is the list of medicines, which contains Fluoxetine as ingredient
Olcare Laboratories
Sun Pharma Laboratories Ltd
Sun Pharma Laboratories Ltd
Intas Pharmaceuticals Ltd
Reliance Formulation Pvt Ltd
Alteus Biogenics Pvt.Ltd
Talent Healthcare
Cadila Pharmaceuticals Ltd
Shine Pharmaceuticals Ltd
Tripada Healthcare Pvt Ltd
Kivi Labs Ltd
Intas Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Intas Pharmaceuticals Ltd
Alteus Biogenics Pvt.Ltd
Kivi Labs Ltd
Alteus Biogenics Pvt.Ltd
Talent Healthcare
Tas Med (India) Private Ltd.
Cadila Pharmaceuticals Ltd
Fluoxetine belongs to the class selective serotonin reuptake inhibitors. It works by inhibiting the reuptake of serotonin thus increasing its concentration in the brain and helps in reducing the symptoms.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Disease

Depression

Major
Use with caution the patients suffering from depression and other psychiatric disorders due to the increased risk of suicidal thoughts especially at the beginning of the treatment and at the time of dose change. Discontinue the medicine and inform the doctor if these symptoms appear.

Glaucoma

Moderate
Use with caution in the patients with angle-closure glaucoma or history of glaucoma due to the risk of increasing the intraocular pressure.

Interaction with Alcohol

Alcohol

Moderate
Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving or operating heavy machinery.

Interaction with Lab Test

Lab

Information not available.

Interaction with Food

Food

Information not available.

Interaction with Medicine

Tramadol

Major
Fluoxetine is not recommended with tramadol due to increase in the risk of seizures, confusion, and increased heartbeat. This interaction is more likely to occur in the elderly population with a history of seizures or alcohol withdrawal. Inform the doctor if these medicines are taken together. An alternate medicine should be considered based on the clinical condition.

Diuretics

Moderate
Fluoxetine may cause low blood sodium levels and this risk may increase if taken with diuretics like furosemide. Frequent monitoring of blood pressure and kidney function tests are necessary. Dose adjustments or an alternate medicine should be considered based on the clinical condition.

Monoamine oxidase inhibitors

Major
Fluoxetine is not recommended with monoamine oxidase inhibitors like selegiline, isocarboxazid, phenelzine due to increase in the risk of side effects. There should be a minimum of 14 days time gap between these two medications. Inform the doctor if these medicines are taken together. An alternate medicine should be considered based on the clinical condition.
What are you using Fluoxetine for?
Other
Depression
Obsessive Compulsive Disorder
Panic disorder
Bulimia
Premenstrual Dysphoric Disorder
Pain
How much was the improvement?
Excellent
Average
Poor
How long did it take before seeing improvement?
More than 2 days
Within a day
Within 6 hours
Within 2 days
Within 2 hours
How frequently did you take this medicine?
Once a day
Thrice a day
Twice a day
Four times A Day
Not taking on daily level
How did you take this medicine?
With Food
Empty stomach
With or without food
What were the side effects of this medicine?
Dry Mouth
Increased sweating
Anxiety
Fever or chills
Skin Rash
Restlessness
Muscle or joint pain
Decreased appetite
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

I am taking fluoxetine from several months for OCD. Can I use liver tonic with fluoxetine? Can I use antibiotic like cephalexin, cefixime in infection cases with fluoxetine? And what are the drugs which should not be taken with fluoxetine?

MBBS, MD - Psychiatry
Psychiatrist, Delhi
Hello. I would advise you to inform your physician beforehand that you are taking fluoxetine so that he can prescribe any other medicine, accordingly. Thanks.
4 people found this helpful

For depression and anxiety please suggest me the recommended dosage of fluoxetine.

MD-Psychiatry, MBBS, Certificate in Medical Neuroscience
Psychiatrist, Akola
For depression and anxiety please suggest me the recommended dosage of fluoxetine.
It's not that simple my friend. You need to consult a Psychiatrist, who ll help you understand your problems. Then only which medicine & what dose can be decided.

I was on fluoxetine medication for a month for my anxiety and depression but it did not work for me and moreover it caused me sexual dysfunction. Now I stopped the fluoxetine how long will the sexual side effect last. I am worried.

MD - Psychiatry
Psychiatrist, Chennai
I was on fluoxetine medication for a month for my anxiety and depression but it did not work for me and moreover it c...
Do not worry it will reverse in few weeks max few months. There are medications for anxiety and depression which does not cause sexual dysfunction. All the best.
1 person found this helpful

I am taking fluoxetine from several month for ocd. Can I take liver tonic and antibiotics when having infection. And which are the drugs to avoid while taking fluoxetine.

BASM, MD, MS (Counseling & Psychotherapy), MSc - Psychology, Certificate in Clinical psychology of children and Young People, Certificate in Psychological First Aid, Certificate in Positive Psychology, Positive Psychiatry and Mental Health
Psychologist, Palakkad
Obsessive-compulsive disorder (OCD) is a common mental health problem. Symptoms typically include recurring thoughts and repetitive actions in response to the recurring thoughts. A common example is recurring thoughts about germs and dirt, with a ...

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Table of Content
About Fluoxetine
When is Fluoxetine prescribed?
What are the contraindications of Fluoxetine ?
What are the side effects of Fluoxetine ?
Key highlights of Fluoxetine
What are the dosage instructions?
Where is the Fluoxetine approved?
Medicines containing Fluoxetine
How does medicine works?
What are the interactions for Fluoxetine ?