Hi. My mother is aged 58 years, she is suffering from rheumatoid arthritis since from the year 2002. Clinical testing were done and found ESR 80-100 range, due to extreme pain in joints, in the year 2003 her right TKR were done. Due to disease gradually her both hand fingers and foot fingers deformed. Later in the year 2009 and 2012 left hip and left TKR were done respectively. Now also she is struggling to walk and very difficult to sit on floor, and she is struggling to climb steps, totally she is suffering from severe joints pain. Kindly advise for this issues and please make her life into normal.