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Overview

Skin Biopsy: Treatment, Procedure, Cost and Side Effects

What is the treatment?

A skin biopsy is a process in which a part of the skin tissue is peeled off, processed and then studied under the microscope. When there is a skin lesion, some sample tissue is removed from that region of the skin to get it tested for any potential abnormality. A number of methods can be employed for the same depending on the loaction and the size of the lesion. The sample tissue is then put in a formaldehyde solution or a sterile vessel if it is suspected to be infected. The tissue gets processed in this way and is then examined under the microscope.

When a part of the skin unusually changes colour, size, shape or appearance in general or does not heal even long after any injury, a skin biopsy should ideally be performed. The procedure is primarily performed to diagnose skin cancer. A skin lesion biopsy can also diagnose any skin disease like psoriasis and a fungal or bacterial infection. If you see something abnormal on your skin along the lines of a skin lesion, you should not ignore it and get it checked as fast as possible to identify skin cancer that can result in early treatment.

How is the treatment done?

The area of the skin from where the sample tissue would be collected is wipes with little alcohol. Sometimes, a marker is also used to mark the particular area. The method employed to obtain the skin sample depends on the location and the size of the lesion. There are three primary methods by which a skin biopsy may be performed- shave biopsy, punch biosy and excision.

Shave Biopsy: In this procedure, the tissue sample is removed when that portion of the skin is under local anaesthesia. Then the sample tissue is shaved off using a scalpel. No stitches are required to heal the area. In the case of any bleeding, some chemical is applied to control it. A sterile surgical drape is then used to keep the biopsy site covered.

Punch Biopsy: In this process too, the sample tissue is removed under local anaesthesia. A small and sharp tool, called punch, resembling a cookie cutter, is positioned on the skin lesion, forced down and then mildly rotated to get a circular patch of skin. The sample skin is detached from the tissue with a needle or a forceps. A few stitches may be required if a large skin sample has been removed and pressure is applied to stop bleeding. A sterile dressing or bandage is used to cover the biopsy site.

Excision: Again, the procedure is performed under local anaesthesia. Here a scalpel is used to remove the whole lesion. Skin grafting is required for large excisions and the biopsy site is then covered with a sterile dressing.

Who is eligible for the treatment? (When is the treatment done?)

A person should get a skin biopsy done as soon as he discovers a lesion or an area of the skin that has abnormally changed appearance without any apparent reason. A skin lesion biopsy can detect a skin condition like psoriasis and something as dangerous as skin cancer. If skin cancer is detected early, then it can be treated on priority and get completely cured in certain cases.

Who is not eligible for the treatment?

Any person with an atypical skin lesion is eligible for a skin biopsy. However, there are some factors about which the doctor should know before the procedure is performed. If a person is taking any anti-inflammatory medicine or corticosteroids, the doctor should know about that as in such cases the results of the biopsy may be inaccurate. As skin biopsy involves cutting into the skin, the patient hould also inform the doctor about any bleeding problem or if he is taking any blood-diluting medication like aspirin or warfarin. And the patient must inform the doctor if she is pregnant.

Are there any side effects?

Even though it's very unlikely, the patient may be susceptible to infection at the biopsy site and also a very little risk of continuous bleeding. The patient can form a scar at the biopsy site.

What are the post-treatment guidelines?

The patient has to take good care of the biopsy site until it completely heals and keep it dry and clean. Stitches are taken out a few days after the surgery and the sterile dressing or bandage remains in place for about two weeks till it falls off on its own. Patients often develop a fever right after a skin biopsy and there might be swelling, redness and some pain at the biopsy site as well. While it is normal for the biopsy site to bleed for some time, the patient must contact the doctor immediately in case of excessive bleeding.

How long does it take to recover?

The biopsy site heals completely after 2-3 weeks if the patient follows the post-treatment guidelines strictly.

What is the price of the treatment in India?

The cost of the procedure can vary. However, the average price in India ranges between Rs.600 and Rs.2600.

Are the results of the treatment permanent?

A skin lesion biopsy can result in scarring at the biopsy site and its permanence varies from person to person.

Safety: High Effectiveness: High Timeliness: High Relative Risk: Low Side Effects: Low Time For Recovery: High Price Range:

Rs.600-Rs.2600

Popular Health Tips

Things you need to know before a skin biopsy

MD - Dermatology , Venereology & Leprosy, MBBS
Dermatologist, Gurgaon
Things you need to know before a skin biopsy

Examination of a sample of skin (removed/extracted from the body) under a microscope is known as skin biopsy. It helps in diagnosing skin infections, conditions like psoriasis and diseases like skin cancer.
There are some things you need to know before getting a skin biopsy

How to prepare for this procedure?
You need to inform the doctor about several things like-
1. If you have any allergies
2. If you are or might be pregnant
3. If you are suffering from any kind of bleeding problems and taking medicines like Aspirin or warfarin
4. If you are on any kind of anti-inflammatory medication like prednisone

How does it feel?
When the skin sample is removed, it is done under the influence of anesthesia. Therefore, no such pain is felt at all. The only time a little sting is felt, is when the local anesthesia is injected.


What are the risks associated with skin biopsy?
There are no life threatening risks associated with a skin biopsy. But sometimes, a skin biopsy can cause skin infection or may result in persistent bleeding or even a scar may develop.

Post procedure care tips
After a skin biopsy, you will be instructed by your doctor on how to take care of the area of the skin where the procedure is done. Some of these instructions include
1. The biopsy site must be kept clean and dry
2. It would take 3-14 days for the removal of the stitch from the site
3. In case of pain, excessive bleeding, swelling, redness or fever, inform your doctor

Results
The results of such biopsy tests take 3-10 days to get available. If you wish to discuss about any specific problem, you can consult a dermatologist.

2553 people found this helpful

What Are The Risks Associated With Skin Biopsy?

MD - Dermatology, MBBS, Diplomate of American Board of Laser Surgery
Dermatologist, Delhi
What Are The Risks Associated With Skin Biopsy?

Examination of a sample of skin (removed/extracted from the body) under a microscope is known as skin biopsy. It helps in diagnosing skin infections, conditions like psoriasis and diseases like skin cancer.
There are some things you need to know before getting a skin biopsy

How to prepare for this procedure?
You need to inform the doctor about several things like-
1. If you have any allergies
2. If you are or might be pregnant
3. If you are suffering from any kind of bleeding problems and taking medicines like Aspirin or warfarin
4. If you are on any kind of anti-inflammatory medication like prednisone

How does it feel?
When the skin sample is removed, it is done under the influence of anesthesia. Therefore, no such pain is felt at all. The only time a little sting is felt, is when the local anesthesia is injected.


What are the risks associated with skin biopsy?
There are no life threatening risks associated with a skin biopsy. But sometimes, a skin biopsy can cause skin infection or may result in persistent bleeding or even a scar may develop.

Post procedure care tips
After a skin biopsy, you will be instructed by your doctor on how to take care of the area of the skin where the procedure is done. Some of these instructions include
1. The biopsy site must be kept clean and dry
2. It would take 3-14 days for the removal of the stitch from the site
3. In case of pain, excessive bleeding, swelling, redness or fever, inform your doctor

Results
The results of such biopsy tests take 3-10 days to get available. If you wish to discuss about any specific problem, you can consult a dermatologist.

4 people found this helpful

Breast Biopsy- When To Go For It?

DGO, MBBS
Gynaecologist, Delhi
Breast Biopsy- When To Go For It?

An early detection of cancer increases the chance of cure and survival; the same is true in the case of breast cancer as well. However, globally, an estimated 80% of women that undergo breast biopsy for diagnosis do not have breast cancer. So, when should a woman undergo breast biopsy? Read on to get an in-depth understanding.

What is a breast biopsy?
A breast biopsy is a clinical test that detects unhealthy tissues and suspicious fluids in the human breast. The sick cells are removed and examined under a microscope in a bid to detect breast cancer. A biopsy is the only means of determining whether the suspect area in the breast is affected by cancer.

What are the types of breast biopsy?
Various types of breast biopsy procedures are practised. These include fine-needle aspiration biopsy, core needle biopsy, stereotactic biopsy, ultrasound-guided core needle biopsy, MRI-guided core needle biopsy, and surgical biopsy.

The fine-needle aspiration biopsy is the most uncomplicated process that can evaluate a lump which can be felt during a clinical exam. Core needle biopsy may be used for evaluating lumps that are visible on a mammogram or ultrasound scanning. Stereotactic biopsy utilizes mammograms to pinpoint a location of suspicion within the breast.

Ultrasound-guided and MRI-guided core needle biopsy methods are used to guide core needle biopsy processes.

When is it recommended?
A gynaecologist may recommend undergoing a breast biopsy if he or she suspects a lump or thickening of the flesh in the breast. Mammograms and ultrasound or MRI techniques may detect a suspicious finding. Subsequently, patients have to undergo a breast biopsy to confirm the presence (or absence) of cancerous growth in the breast. Doctors and health professionals also recommend the test if conditions such as unusual areolar or nipple changes (such as scaling, crusting, bloody discharge or dimpled skin) are detected.

What are the preparations involved?
Before undergoing the breast biopsy, patients should inform their doctors about any allergies or any consumption of prescribed medication such as aspirin or other blood-thinning tablets. Similarly, doctors must be notified in advance if patients are unable to lie on their stomach for a long stretch of time. When biopsy procedures involve magnetic resonance imaging, doctors must be told if the patient has a cardiac pacemaker or any other electronic device implanted in their body. Also, health professionals must be advised when biopsy candidates are pregnant. These precautions are necessary because an MRI biopsy may not be suitable in these circumstances.

Women that are scheduled to undergo biopsy must wear an excellent supporting brassiere since they may have to hold a cold pack in the biopsy site. The correct undergarment can hold the pack in place and offers the necessary support.

It is worthy to note that multiple breast biopsy procedures may be required to obtain a tissue sample from the patient’s breast. The attending gynaecologist may recommend a particular method based on the size, location, and other individual characteristics of a lump in the breast.

So, you might have to undergo the procedure if recommended by your doctor. Patients can seek a second opinion if skeptical in this regard.

1682 people found this helpful

Tumor Biopsy: Things To Know!

MBBS, MS - General Surgery
General Surgeon, Pune
Tumor Biopsy: Things To Know!

A procedure done to remove a piece of tissue from your body so that it can be analyzed in a laboratory is termed as 'biopsy'.

A biopsy is done to determine whether you have cancer or some other condition. They help to differentiate cancerous cells from noncancerous cells.

It is performed by a surgeon, interventional radiologist, or an interventional cardiologist.

Types of biopsy procedures

  1. Bone Marrow biopsy.
  2. Bone marrow is the spongy material inside some of your larger bones where blood cells are produced.
  3. This biopsy is done if the doctor suspects cancer to have originated in or travelled to your bone marrow.
  4. Bone marrow biopsy is done to diagnose leukemia, lymphoma and multiple myeloma.
  5. A bone marrow biopsy detects cancers that started elsewhere and traveled to the bone marrow.

Endoscopic biopsy

  1. During endoscopy, your doctor uses a thin, flexible tube (endoscope) with a light on the end to see structures inside your body. It has a close-focusing telescope on the end for viewing.
  2. To analyze cells of a tissue, special tools are passed through the tube.
  3. Tubes are inserted through your mouth, rectum, urinary tract or a small incision in your skin.
  4. Examples: Cystoscopy to collect tissue from inside your bladder, bronchoscopy to get tissue from inside your lung and colonoscopy to collect tissue from inside your colon.

Needle biopsy

  1. During a needle biopsy, the doctor uses a special needle to extract cells from a suspicious area.
  2. A needle biopsy is often used on tumors that the doctor can feel through your skin, such as suspicious breast lumps and enlarged lymph nodes.

Needle biopsy procedures include:

  1. Fine-needle aspiration
  2. Core needle biopsy
  3. Vacuum-assisted biopsy

Skin biopsy
A skin (cutaneous) biopsy removes cells from the surface of your body. A skin biopsy is used to diagnose skin conditions, including melanoma and other cancers. The type of skin biopsy to be done depends on the type of cancer suspected.

Skin biopsy procedures include:

  1. Shave biopsy- The doctor uses a tool similar to a razor to scrape the surface of your skin.
  2. Punch biopsy- The doctor uses a circular tool to remove a small section of your skin's deeper layers.
  3. Incisional biopsy- The doctor uses a scalpel to remove a small area of skin.
  4. Excisional biopsy- The doctor removes an entire lump

You receive a local anesthetic to numb the biopsy site before the procedure.

Biopsy analysis and results
A biopsy guides the doctor to determine cancer's grade. The grade is sometimes expressed as a number on a scale of 1 to 4 and is determined by how cancer cells look under the microscope.

In case you have a concern or query you can always consult an expert & get answers to your questions!

2657 people found this helpful

Renal Biopsy - When Should You Go For It?

MBBS, DM - Nephrology, MD-General Medicine
Nephrologist, Delhi
Renal Biopsy - When Should You Go For It?

Kidneys play an important metabolic role and are essential for balancing salt, minerals and water in the body. They also play a significant role in removing waste products from the body. They make urine, which contains all the waste materials that are eliminated from the body. They also play an important role in blood pressure regulation and in maintaining the balance of various minerals in the body. Any suspected kidney damage should be confirmed by a kidney biopsy, which will reveal the exact disease, thereby directing towards the appropriate treatment. 

Why and when is it done? 

A renal or kidney biopsy is done in the following situations: 

  1. When there is abnormal protein in the blood or urine, which is indicative of a kidney disease, and the exact cause needs to be found out
  2. When kidney failure is suggested by blood tests but cause is not clear 
  3. To find the cause of bleeding in the urine (haematuria) 
  4. To identify and/or confirm diagnosis after a CT scan or ultrasound 
  5. To check how well a transplanted kidney has been received 

Know about the procedure 

A renal biopsy is mostly done as an outpatient procedure and is a type of biopsy known as percutaneous biopsy (biopsy where a needle is inserted through the skin into the renal tissue). Very rarely, it may be combined with the CT scan or ultrasound and be done in the radiology department. This may be done on inpatients. The patient is made to lie on his/her back and a local anesthetic is used on the area of the injection. A thin, long needle is directed towards the area of the kidney from where some kidney tissue is removed for sampling.

In some cases, the direction of the needle may be decided by a CT scan or ultrasound. While this is a closed biopsy procedure, in some cases, as a part of the surgery, open biopsies may also be obtained, where a sample of tissue is extracted for analysis. 

Recovering from a biopsy 
The person would need some time to recover from the procedure, as there would be some discomfort at the site of a needle insertion. Vital signs would be monitored for the next couple of hours during which the person would also be monitored for internal bleeding. A pain reliever can be used if required. Haematuria or blood-tinged urine can be seen disappearing within the next 12 hours. Very rarely the bleeding can be severe and require angiography and further procedures. The person should also avoid strenuous activities for the next few days. 

In case you have a concern or query you can always consult an expert & get answers to your questions!

2942 people found this helpful

Popular Questions & Answers

I have spine potts and biopsy is also done but now problem is at biopsy region pus is outsided and skin come up what can I do age is 30 years female.

MBBS
General Physician, Faridabad
beter consult the same doctor and ask about your problem and he will guide you beter because he has done the procedure. . potts spine is completely treatable. welcome for further help.

My grandmother has a skin tumor on the back of her head. The biopsy report says it has malignancy. So what to do?

MD - Pathology
General Physician, Amritsar
Must be removed surgically as soon as possible depending on patient's fitness for surgery. See a surgeon.

Diagnosed with oral lichen planus Dr. said no need of biopsy can it lead to cancer ,what are the chances? I am having burning ulcers below the lower lip. Is biopsy necessary.

BDS
Dentist, Kochi
Treatment for leukoplakia, if needed, involves removing the source of irritation. If leukoplakia is caused by a rough tooth or an irregular surface on a denture or a filling, the tooth will be smoothed and dental appliances repaired. If leukoplakia is caused by smoking, you will be asked to minimize or stop smoking or using other tobacco products. Leukoplakia is usually harmless, and lesions usually clear in a few weeks or months after the source of irritation is removed. If eliminating the source of irritation is ineffective in reducing leukoplakia, the lesion may need to be surgically removed. The lesion can be removed either by an oral surgeon.

I am 32 years old male. My skin is fair whitish. I am having dark scars, spots on my legs for past 2 years. I undergone biopsy test. The skin where the biopsy was done has very dark spot. I used momerex cream, but no relief. Is there any other creams, soaps to reduce dark spots?

BAMS
Ayurveda, Ambala
´╗┐Dear Follow these best tips to lightens and remove the dark spots- 1. Take fuller, s earth (multani mitti) and sandalwood powder (chandan powder) mixed in same quantity mixed in water and apply on the mark in night and wash it after 1 hour. It will slowly removes the spots. 2. Take a piece of aloe vera. Apply gel of leaves on mark daily. Wash it after 30 minutes. 3. Crush one tomato and apply the paste on mark. It will remove the spots definitly. 4.Soak cotton gauze in rose water and clean the dark spots 2-3 times daily. 5. Take carotene rich vegetable suchas carrots, beetroot and fruits- mango, pineapple, strawberry regularly. 6.Avoid use of any cosmetic products. 7.Avoid continous long hours exposure of sunlight.
1 person found this helpful

Table of Content

What is the treatment?
How is the treatment done?
Who is eligible for the treatment? (When is the treatment done?)
Who is not eligible for the treatment?
Are there any side effects?
What are the post-treatment guidelines?
How long does it take to recover?
What is the price of the treatment in India?
Are the results of the treatment permanent?
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Know More About Skin Care!
How to protect your skin from Sun Tan?

Hello everyone. I am Dr. Anupriya Goel from Berkowitz Hair And Skin Clinic. Today I am going to give you tips on how to take care of your skin during summers.

Now, the most common problem that people come to me with during summers is sun tan and pigmentation and my prevention for the same would be prevention than cure. Now, you must prevent your skin from the harmful radiation of from the sun which not only leads to sun tan and pigmentation but also leads to photo damage of your skin which leads to early signs of aging. So the main component which must be applied to prevent your skin from this skin damage is the application of a broad spectrum sunscreen. So, a sunscreen must be minimum SPF 30, UVA++, must be applied 15-20 minutes before going out in the sun, must be re-applied every 3 hours if you are in the sun continuously and should be applied in adequate quantities.

Now, a lot of people even though they apply sunscreen, as they do not apply in adequate quantity, is not very effective. So a minimum of 3 fingertips units must be applied on the face and the neck. Now, along with application of the sunscreen, application of a vitamin C serum is also very important. This is because, due to the exposure to UV radiations and due to environmental pollutants there is generation of free radicals or reactive oxygen species which not only damages your skin cells but it is also damages your melanin producing cells or melanocides. So, this can be prevented by intake of anti-oxidants in the form of citrus fruits, oral supplements and Vitamin C serum. Hence, I would advise that application of a Vitamin C serum and a sunscreen is a must every single day of your life especially in summers.

Now, at night time, the most important step before going to bed is cleansing your face. Many people undermine the importance of cleaning their face before going to bed. This step not only removes the excessive sebum and excessive production of sweat that is mainly produced during summers but it also removes the environmental pollutants. After cleansing your face, you must apply a topical agent containing alphahydroxy acid, containing glycolic acid, lactic acid or melanic acid at least twice a week. This step not only improves the top layer of your skin by decreasing the amount of sebum and removing the dead skin cells but it also acts on a deeper level of your skin producing increased collagen, and meuko polysaccharides which increases the thickness and quality of your skin.

On the other days of the week, you must also apply a moisturizing cream or a hydrating gel. The important properties of a good moisturizing cream are that it contains humectants which attracts water to the skin, maintains or traps water to your skin and emollients which smoothen up your skin. A good property of a moisturizing gel should be that it should leave your skin smooth and supple and not very sticky. Now, other than applying these moisturizing creams and hydrating gels, it is very important to take care of the hydration of your body by taking minimum 2-3 liters of water every single day. So, just to summarize it, during summers, during daytime, you must apply Vitamin C serum and a sunscreen and at night, you must apply a good moisturizing gel along with glycolic acid containing topical agents along with a healthy diet and cleansing your face.

If you do all these steps for a minimum of 3-6 months, you will definitely see a younger and brighter looking skin. Wish you all a very healthy and beautiful summer. Thank you.
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Skin Care Treatment
Few treatments for skin rejuvenation and hair regrowth
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Skin Care Tips
Hello, I am Shruti Kohli. I am a consultant Dermatologist in cosmetologist in Sarvodaya Hospital, Sec-8, Faridabad. Also, I have a clinic in Sec- 15, Faridabad by the name of Crimson Clinic. I have been practising from last 12 years.

Today, I am going to talk about the "summer skin care tips".

Summers brings a lot of skin problems, such as Fungal infections, sunburn, excessive sweating and rashes. Here are few tips for the smooth sailing summer,

Use sunscreen before stepping out in the sun, that is the most important preventive step anyone can take in the summer season. The sun screen should be minimum SPF of 15 and should protect against both UVA and UVB.
Apply the sunscreen 15 minutes prior to go to the sun. And it can be applied after every 3-4 hours.
The sun also has a bad effect on the lips. In order to protect them, you can moisturize them by applying lip balm with SPF of 15, as and when required.
For the face cleaning, I would recommend a gentle exfoliating face wash containing glycolic acid, which will help to remove a dead skin as well as the harmful effect of sweat and pollutants from your skin.
After cleansing of the skin, it is important to use light water base moisturizer to keep your skin hydrated.
Avoid heavy creams and oils as the skin breakouts.
If you are exposed to the sun for long period, then aloe vera gel is recommended, as it is a soothing and cooling agent. also it has antioxidant properties. It can also prevent damaging of the skin of free radicles.
Aloe vera can also be used a cooling mask occasionally.
I would recommend washing off yourself twice daily with cold water, in order to remove the pollutants.
Also, use a white broad hat to protect your skin, especially the skin of your face. Or you can use an umbrella while being exposed to the sun.
Eat plenty of watermelon and muskmelon daily.
There are certain foods which give inherent protection against the sun. These include tomatoes, berries, citrus fruits, nuts which contain Vitamin C.
And the last is, hydrate yourself regularly. drink atleast 12-15 glass of water daily for a glowing, youthful and healthy skin. Coconut water also works well and is recommended in your daily routine.
Summer will be fun if you follow the simple tips given by me. You can contact me for any skin related problem, through Lybrate or you can also take a direct appointment in my clinic which is in Sec-15 A, by the name of Crimson clinic.

Thank you.



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Know More About Skin Treatment
Different techniques for skin treatment
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Skin Diseases
Ayurvedic Treatment For Skin Diseases
Having issues? Consult a doctor for medical advice