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Hypogonadism - Symptom, Treatment And Causes

What exactly is Hypogonadism? Variants of Hypogonadism Why do they take place? Causes of Central Hypogonadism

What exactly is Hypogonadism?

Hypogonadism is a type of sexual condition that takes place when the sex glands of a person do not function properly resulting in either complete lack of production of sex hormones or in minute amounts. The sex glands are also referred to as gonads and happen to be chiefly the ovaries in females and testes in men. Secondary sex characteristics such as the development of testes in males and the development of breasts in women in addition to the growth of pubic hair are controlled to a large extent by sex hormones. Hormones also serve to perform a function in the production of sperms and in the menstrual cycle in females.

Hypogonadism is also referred to as gonad deficiency. In males, it is also termed as andropause or a condition of low serum testosterone.

Variants of Hypogonadism

Hypogonadism has been found to occur in two different variants viz. central and primary hypogonadism.

Primary Hypogonadism - A person suffering from primary hypogonadism basically suffers from a deficiency of sex hormones which occurs due to problematic gonads. They continue to receive instructions from the brain to produce sex hormones but simply cannot produce them.

Central Hypogonadism – Central Hypogonadism is also sometimes referred to as secondary hypogonadism. The culprit in this variant of the disease is the brain. This condition results from the dysfunction of the pituitary gland and the hypothalamus which is responsible for controlling the gonads.

Why do they take place?

  • The causes which instigate primary hypogonadism are:
  • The primary issue may lie with the genes. Genetic disorders like Klinefelter syndrome and Turner syndrome often result in primary hypogonadism.
  • Some autoimmune disorders also may result in the condition. Such disorders include hypoparathyroidism and Addison’s disease.
  • Infections that are of a severe nature may also result in primary hypogonadism.
  • Diseases of the liver are another cause of this variant of hypogonadism.
  • Kidney diseases may also eventually lead to primary hypogonadism.
  • Another cause may be undescended testes.
  • If your body happens to absorb too much of iron, it leads to hemochromatosis which too may serve to lead to the disease.
  • Exposure to radiation is another common cause.
  • Surgery performed on the sex organs may result in the disease.

Causes of Central Hypogonadism

Secondary or Central Hypogonadism may result from:

  • Disorders of the genes like Kallmann syndrome.
  • Infections like AIDS and HIV.
  • Pituitary gland disorders.
  • Inflammatory diseases.
  • Rapid loss of weight.
  • Obesity
  • Use of opiates or steroids typically when used for a long time.
  • Deficiency in nutrition.
  • Exposure to radiation.
  • Surgery performed on the brain.
  • If the hypothalamus or the pituitary is injured for any reason.
  • Tumors around or in the pituitary.

Popular Questions & Answers

I am 31 years old male. I feel lack of sexual desire and sometimes problem with erection. I also feel less energetic, mood change irritation, lack of focus etc lately. I got my testosterone level checked and it came out to be 270 ng/dl. My questions are:- 1. Is this testosterone level really low for the person of my age? I have heard that at this age it should be at least 600 plus. 2. Can the low testosterone level be the reason behind lack of desire, erection and other issues I am facing? 3. I use tadalafil while having intercourse but still sometime face erection issue. My wife got pregnant 2 times in last two years but both the pregnancies ended up in miscarriage? I want to know whether using tadalafil or low testosterone could be in any way a reason for miscarriage? 4. Is it true that I could notice sureshot increment in my libido if my testosterone level increases drastically? Means is it guaranteed that my sexual life will surely improve if my testosterone levels are on the higher side. Eg. 700 ng/dl. I desperately need it. 5. I have already started working out again (i used to be a powerlifter earlier, improve my diet and lifestyle. What are the other suggested treatment for low testosterone? I would appreciate if I could get the pointwise answers specific to my queries. Thank you.

MBBS, MS- General Surgery, MCH- Urology, Fellowship Minimal Access Surgery
Urologist, Mumbai
Your testosterone level seems to be on borderline, you need hormonal evaluation just a single testosterone level cannot be conclusive you need to visit either a urologist or an endocrinologist in your area and get evaluated. You will be clinically...
5 people found this helpful

Cernos 40 mg tablets can reduce the sperm count. I am using these tablets since 1 month. Pls tell me in detail. I am stop taking these tablets or not. Tell me.

MS General Surgery, DNB( Urology)
Urologist, Jamshedpur
Dear lybrate-user, yes cernos tablet can reduce sperm count by feedback mechanism. If you are looking for fertility then stop it. You can consult local urologist, he will guide you. Regards.
4 people found this helpful

Does aquaviron injection reduces stops my natural testosterone growth. I mean to say after injected does my testosterone hormone stops making by own. please suggest.

M.D (HOMEOPATHY), MBA (Healthcare)
Homeopathy Doctor, Gulbarga
Yes your guess is absolutely right. When you take hormones externally, internal production is hampered.
1 person found this helpful

How much mg take ashwagandha tablet daily for increase testosterone or fertility. now I am taking 920 mg aswgandha amway nutrilite tablet.

BASM, MD, MS (Counseling & Psychotherapy), MSc - Psychology, Certificate in Clinical psychology of children and Young People, Certificate in Psychological First Aid, Certificate in Positive Psychology, Positive Psychiatry and Mental Health
Psychologist, Palakkad
Dear user. I can understand. Please don't be panic but be serious about the symptoms. What is your age and how you are worried about your infertility? Please provide more information so that we can start the diagnosis process and the treatment. I ...
2 people found this helpful

Today while practicing kabbadi our opponent player unknowingly hitted to my testis region due to that my left testis testis is swelled up and right one is normal please suggest me how can I cure this. Am I need to consult the doctor. Please revert back me.

MBBS, MS - General Surgery, Diplomate of National board in Surgical Oncology
General Surgeon, Kolkata
Yes ypu need to consult doctor trauma can lead to bleeding inside scrotum. This is called hematoma which can cause ireparable damage to your testis so get an usg scrotum done.
1 person found this helpful

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