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Hypogonadism - Symptom, Treatment And Causes

What exactly is Hypogonadism? Variants of Hypogonadism Why do they take place? Causes of Central Hypogonadism

What exactly is Hypogonadism?

Hypogonadism is a type of sexual condition that takes place when the sex glands of a person do not function properly resulting in either complete lack of production of sex hormones or in minute amounts. The sex glands are also referred to as gonads and happen to be chiefly the ovaries in females and testes in men. Secondary sex characteristics such as the development of testes in males and the development of breasts in women in addition to the growth of pubic hair are controlled to a large extent by sex hormones. Hormones also serve to perform a function in the production of sperms and in the menstrual cycle in females.

Hypogonadism is also referred to as gonad deficiency. In males, it is also termed as andropause or a condition of low serum testosterone.

Variants of Hypogonadism

Hypogonadism has been found to occur in two different variants viz. central and primary hypogonadism.

Primary Hypogonadism - A person suffering from primary hypogonadism basically suffers from a deficiency of sex hormones which occurs due to problematic gonads. They continue to receive instructions from the brain to produce sex hormones but simply cannot produce them.

Central Hypogonadism – Central Hypogonadism is also sometimes referred to as secondary hypogonadism. The culprit in this variant of the disease is the brain. This condition results from the dysfunction of the pituitary gland and the hypothalamus which is responsible for controlling the gonads.

Why do they take place?

  • The causes which instigate primary hypogonadism are:
  • The primary issue may lie with the genes. Genetic disorders like Klinefelter syndrome and Turner syndrome often result in primary hypogonadism.
  • Some autoimmune disorders also may result in the condition. Such disorders include hypoparathyroidism and Addison’s disease.
  • Infections that are of a severe nature may also result in primary hypogonadism.
  • Diseases of the liver are another cause of this variant of hypogonadism.
  • Kidney diseases may also eventually lead to primary hypogonadism.
  • Another cause may be undescended testes.
  • If your body happens to absorb too much of iron, it leads to hemochromatosis which too may serve to lead to the disease.
  • Exposure to radiation is another common cause.
  • Surgery performed on the sex organs may result in the disease.

Causes of Central Hypogonadism

Secondary or Central Hypogonadism may result from:

  • Disorders of the genes like Kallmann syndrome.
  • Infections like AIDS and HIV.
  • Pituitary gland disorders.
  • Inflammatory diseases.
  • Rapid loss of weight.
  • Obesity
  • Use of opiates or steroids typically when used for a long time.
  • Deficiency in nutrition.
  • Exposure to radiation.
  • Surgery performed on the brain.
  • If the hypothalamus or the pituitary is injured for any reason.
  • Tumors around or in the pituitary.

Popular Questions & Answers

Good day dr, I have bph, I tried urimax and silodal ,after taking these tab I cannot ejaculate semen ,tried flotral 10 mg it works but after taking for two days I am experiencing breathing problem. Dr. can I take this tab ,twice a week or lower dose. May be 10 mg is tòo high for me. Dr. pls help. thank you in advance.

M.B.B.S, MS, DNB - Urology/Genito - Urinary Surgery
Urologist, Vadodara
Good day, as you are not able to ejaculate are side effects of this drugs so nothing to worry as such, it will revert back once you stop the drug, my advice would be you continue full dose of 10 mg flotral, no harm in that, less dose is not going ...

I am 75 male. Taking himplasia and urimax 0,4 for prostate enlargement / mild nephritis. On telma 20 for hypertension. I lost about 2,5 kg in the last two months. No issues with appetite / bowl movement etc. Will tuberculinum 200 help regain my weight to 54 kg.

M.B.B.S, MS, DNB - Urology/Genito - Urinary Surgery
Urologist, Vadodara
You have multiple problems combined, for your evaluation require detail understanding of your reports, for prostate related problems you need to contact me online.

I am 60 year old I have bph since 4 years pls guide me if I need to choose tablet should I take alfoo or maxvoid plus 8 mg which is better prostate size 37 cc in ultrasound.

M.B.B.S, MS, DNB - Urology/Genito - Urinary Surgery
Urologist, Vadodara
It depends on your severity of symptoms and sexual life, if you are completely satisfied with any of drug and sexually active then I will suggest to continue the alfoo or efficacy is higher with maxvoid and for dutesteride you need to see psa plea...

Hi I am 25 year old. I having hypothyroid since 2 year. I am taking 50 mcg thyrox .still I am not reducing weight. Having period problems also. My tsh level is 3.32 .weight 80 kg. Height 5" 5 inch.will I increase my lt4 to 100 mcg. For reducing weight. I have tried diet and all. Nothing works. Help me.

MBBS, CCEBDM, Diploma in Diabetology, Diploma in Clinical Nutrition & Dietetics, Cetificate Course In Thyroid Disorders Management (CCMTD)
Endocrinologist, Dharwad
Hdello, thanks for the query. Madam your tsh now is with in the specified limit with current dosage of levothyroxine (50 mcg). The recommended range is 0.5 to 4.5 or 5 mu/l. Usually at 3 to 4 mu/l level all the symptoms are in check and even effor...
1 person found this helpful

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