I am suffering from Major depression since last 20 years. Medications I am using currently Paroxetine 50 mg, Lamictal 300 mg. My predominant symptoms that are not going away since last 20 years is lot of weakness in calfs, short term memory is very very poor. Lamictal helped me to great extent in improving my mood more than antidepressant whether Lamictal dose can be increased from 300 mg currently. Any add on medication to address severe short-term memory issue n weakness n tiredness in legs. Pls help.

Dr. Saranya DevanathanPsychiatrist47yrs exp

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Dear lybrate-user, It is nice of you for fighting against depression since 20 years. Doctors are also researching for newer and newer medicines and treatments. It is good that you are finding lamictal useful. Routinely upto 200 mg is prescribed. At times, it may be taken upto 400 mg also. Talk to your doctor and find out. Discuss with your doctor on add ons. Many of them are available like SamE, 5HT, thyroxine, etc. I don't know your age. Yor memory issue and weaknesses may be due to age related other medical disorders. Consult a physician and get investigated for diabetes, dementia etc.  

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