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Endogest 200mg Soft Gelatin Capsule

Manufacturer :  Cipla Ltd
Medicine Composition :  Natural Micronised Progesterone
Prescription vs OTC : Prescription by Doctor required

About Endogest 200mg Soft Gelatin Capsule

Endogest 200mg Soft Gelatin Capsule is a medication that is used in hormone replacement therapy. This means that it is orally administered into women’s bodies when they do not produce enough progesterone. It reduces menopause symptoms and the risk of cancer of the uterus.

It corrects menstrual disorders in women and can also be used as contraception. Endogest 200mg Soft Gelatin Capsule, belonging to a group of medications called Progestins, works by inducing some changes in endometrium and decreasing the level of estrogen in the uterus.

There are few side effects of using Endogest 200mg Soft Gelatin Capsule. Some of them include nausea, diarrhoea, mood swings, abdominal pain, flatulence, rash, itching, sleepiness, vomitting and dizziness. More serious side effects may include chest pain and discomfort, difficulty in passing urine, great lumps, fever and chills, blurred or loss of vision and convolutions.

You should not use Endogest 200mg Soft Gelatin Capsule if you are allergic to it, or have a heart, blood vessel, or liver disorder. You should not use it If you have had a miscarriage, experience abnormal vaginal bleeding, are pregnant or have breast cancer.

This medicine is not to be given to children. A few other medicines can interact with Endogest 200mg Soft Gelatin Capsule like carbamazepine, ketoconazole, insulin, phenobarbital, venetociax and edoxaban. Therefore, it is advisable to inform your doctor if you take any other medications.

Doctors recommend to take this medicine at bedtime with sufficient amount of water for as long as prescribed. The duration of action of each dose is based on factors like your age, dosage form, etc. In case of overdosing contact your doctor immediately.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the uses of Endogest 200mg Soft Gelatin Capsule

    • Post Menopausal Hormonal Replacement Therapy

      This medicine is used along with estrogen in women who have achieved menopause, but haven't undergone a surgery to remove the uterus (hysterectomy).

    • Amenorrhoea

      This medicine is used to treat absence of menstruation in women of childbearing potential due to a lack of progesterone in their body.

    • Dysfunctional Uterine Bleeding

      This medicine is also used to treat abnormal bleeding from the vagina due to changes in hormone levels but are not caused by a pregnancy or miscarriage.

    • Endometrial Hyperplasia

      This medicine is used to prevent this condition where the female sex hormones are imbalanced and heavy bleeding or intermittent bleeding between periods are experienced.

    • Progesterone Deficiency

      This medicine is used to treat a condition where progesterone level in the body is low and as a result the risk of miscarriage is very high.

    • Premenstrual Syndrome

      This medicine is also used for the treatment of symptoms experienced due to periodic changes in sex hormone levels as a part of the menstrual cycle.

    • Contraception

      This medicine may also be used as a vaginally inserted dosage form to achieve contraception.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the contraindications of Endogest 200mg Soft Gelatin Capsule ?

    • Allergy

      This medicine is not recommended for use if you have a known history of allergy to progesterone or any other ingredient present with it. This medicine might contain peanut oil and should never be used by patients who are allergic to peanuts.

    • Abnormal Vaginal Bleeding

      This medicine is not recommended for use if you have an abnormal bleeding episode which has not been diagnosed by a doctor.

    • Breast Cancer

      This medicine is not recommended for use if you have breast cancer or are suspected to have it. It is not recommended for use if the patient has a history of breast cancer.

    • Miscarriage

      This medicine is not recommended for use if the patient has had an incomplete miscarriage or missed abortion recently.

    • Heart And Blood Vessel Disorder

      This medicine is not recommended for use in patients having an active or historic instance of stroke or heart attack. It should not be used by patients having an active or historic clotting disorder.

    • Liver Disease

      This medicine is not recommended for use in patients having a liver disease or impairment of normal liver function.

    • Pregnancy

      This medicine is not recommended for use if you are pregnant or are suspecting a pregnancy.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the side effects of Endogest 200mg Soft Gelatin Capsule ?

    • Chest Pain

    • Fever

    • Difficulty In Passing Urine

    • Breast Pain

    • Muscle Or Joint Pain

    • White Or Brownish Discharge From The Vagina

    • Headache

    • Dizziness

    • Depression

    • Viral Infections

    • Breast Lumps

    • Loss Of Vision Or Blurred Vision

    • Unexpected Vaginal Bleeding

    • Convulsions

    • Swelling Of Face, Lips, Eyelids, Tongue, Hands And Feet

    • Constipation

    • Nausea Or Vomiting

    • Hot Flashes

    • Hair Loss Or Thinning Of The Hair

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    Key highlights of Endogest 200mg Soft Gelatin Capsule

    • How long is the duration of effect?

      The duration of action of this medicine is subject to vary based on factors like age, dosage form etc.

    • What is the onset of action?

      The time taken for this medicine to show it's effect is subject to vary from one person to another.

    • Are there any pregnancy warnings?

      Use of this medicine is not recommended if you are pregnant or planning a pregnancy in near future. Appropriate means of contraception should be used while using this medicine. Consult your doctor before stopping the use of this medicine.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      Use of this medicine is not recommended if you are breastfeeding. This medicine can pass into the breast milk and may harm the nursing infant.

    • Is It safe with alcohol?

      This fact is unknown whether alcohol consumption is safe or not along with this medicine. Kindly consult your doctor before taking this medicine.

    • Is it safe to drive while on this medicine?

      This medicine affects the alertness of the patient. Thus driving ability of the patient is also affected.

    • Does this affect kidney function?

      Limited information is available on its use in patients with kidney disease. Kindly consult your doctor before taking this medicine.

    • Does this affect liver function?

      Caution must be taken in patient with liver disease. Adjustment of dose might be needed. Kindly consult your doctor before taking this medicine.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the substitutes for Endogest 200mg Soft Gelatin Capsule ?

    Below is the list of medicines, which have the same composition, strength and form as Endogest 200mg Soft Gelatin Capsule , and hence can be used as its substitute.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      Take the missed dose as soon as you remember unless it is almost time for the next scheduled dose. Contact your doctor if you have missed more than one dose.

    • Are there any overdose instructions?

      Contact your doctor if an overdose is suspected. The short-term effects of an overdose could be a headache, dizziness, nausea, and vomiting.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    Where is the Endogest 200mg Soft Gelatin Capsule approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

    How does this medication work?

    This medication belongs to a class known as progestins and makes up for the lack of naturally produced progesterone in women of childbearing age. It also decreases the amount of estrogen produced in the uterus.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Laser Gynae before using this medicine.

      What are the interactions of Endogest 200mg Soft Gelatin Capsule ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Thyroid function tests

        Report the use of progesterone to the doctor before undergoing a thyroid function test. This medicine can interfere with the test and give a false positive result.
      • Interaction with Medicine

        Carbamazepine

        Report the use of either of the medicine to the doctor. You may require a dose adjustment or more frequent monitoring to ensure the safe use of these medicines together. Alternate means of birth control should be discussed with your doctor while using carbamazepine. Do not stop the use of any medication without consulting your doctor.

        Ketoconazole

        Report the use of either of the medicines to the doctor. You may need a dose adjustment and frequent monitoring to safely use these medicines together. Report any instances of nausea, vomiting, or vaginal bleeding to the doctor on priority while using these medicines.

        Insulin

        Report the use of insulin or any other anti-diabetic medicine to the doctor before receiving progesterone. You may need an adjusted dose of the anti-diabetic medicine and more frequent monitoring of blood glucose level in such cases.

        Phenobarbital

        Report the use of either of the medicine to the doctor. You may need a dose adjustment or frequent monitoring to ensure the safe use of these medicines together. Use of progesterone for birth control should be avoided while taking phenobarbital. Do not stop the use of any medicine without consulting your doctor.

        Venetoclax

        Report the use of either of the medicine to the doctor. You may require a dose adjustment and frequent monitoring to safely use these medicines together. Report any side effects like vomiting, diarrhea, fatigue etc to the doctor. You doctor may prescribe safer alternatives that do not interact in such cases.

        Edoxaban

        Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring to safely use them together. In some cases, an alternate medicine may be prescribed to avoid interactions and unwanted side effects like unusual bleeding and bruising. Symptoms like dizziness, presence of blood in stool or vomit, severe headache etc should be reported to the doctor on priority while taking these medicines together.
      • Interaction with Disease

        Breast Cancer

        Use of this medicine is not recommended for patients having an active case of breast cancer or are suspected of having it. Report all such instance including occurrence in the past to the doctor so that an informed decision can be taken in regards to the future treatment plan.

        Liver Disease

        Use of this medicine is not recommended if the patient has a liver disease or the normal liver function is impaired.

        Thromboembolism

        Use of this medicine is not recommended in patients having a clotting disorder in which the formed clot moves from one place and lodges in another place.

        Depression

        This medicine should be used with caution in patients having episodes of depression or having a history of depression especially when estrogen is also administered in combination.

        Retinal Thrombosis

        Use of this medicine can sometimes cause a loss of vision by blocking the flow of blood from the retina to the heart. Hence caution should be exercised while using it and any abnormality in vision should be reported to the doctor.
      • Interaction with Food

        Information not available.

      FAQs about Endogest 200mg Soft Gelatin Capsule

      • Ques : What is Endogest 200mg Soft Gelatin Capsule?

        Ans : Endogest 200mg Soft Gelatin Capsule is a type of progesterone hormone which is extracted from plants, but its property matches with the human progesterone. This medicine undergoes a process called micronization where the size of the natural progesterone is reduced. The small size of the progesterone particles enhances its dissolution and absorption. This provides better availability of Endogest 200mg Soft Gelatin Capsule in the body and decreases its side effects.

      • Ques : What is Endogest 200mg Soft Gelatin Capsule used to treat?

        Ans : It is used to treat various disorders. It is given to women with secondary amenorrhea. It supports pregnancy, prevents premature labor, and treats bleeding disorders that may occur before menopause.

      • Ques : Can you take Endogest 200mg Soft Gelatin Capsule every day?

        Ans : Yes, it can be consumed every day. It is usually prescribed to be taken once daily in the evening or at bedtime. The usual duration of prescription may vary from 10-12 days a month to 25 days a month.

      • Ques : Does Endogest 200mg Soft Gelatin Capsule cause weight gain?

        Ans : Yes, Endogest 200mg Soft Gelatin Capsule may cause weight gain. However, it is advised to contact your doctor in case your weight gain is worrying you.

      • Ques : Is Endogest 200mg Soft Gelatin Capsule safe?

        Ans : Yes, Endogest 200mg Soft Gelatin Capsule is safer as compared to the normal synthetic progesterone. It is small in size which helps the body to absorb it easily. It is advised to take Endogest 200mg Soft Gelatin Capsule as per the doctor’s prescription.

      • Ques : How is Endogest 200mg Soft Gelatin Capsule beneficial for fertility and pregnancy?

        Ans : It is a very crucial hormone in fertility. It prepares the uterus for pregnancy and also helps maintain it. Endogest 200mg Soft Gelatin Capsule is also used to prevent premature labor.

      References

      • Progesterone-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/progesterone

      • Progesterone-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 1 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00396

      • Progesterone Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 1 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Progesterone

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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