I am using Calcium with vitamin D tablet 500mg, Vitamin E capsules 200mg, since last 6 months for treatment of my osteopenia. Pl advice that for which purpose Vitamin E is necessary to use. Due to regular use of these Medicines I am suffering with heavy Constipation daily. I am taking daily at bedtime cremaffin/Lactulose syrup 30 ml/ Isabgol husk 5 gm/Tirfals churn 10 gm but no relief in my constipation. My stool is dry & hard & after applying much strain it comes out. I am taking fibre diet, fruits & drinks 4 lt water daily. I am vegetarian & of 67 years age. I am also using diabetes2 medicines glimepiride 1mg od, Metformin SR 500 mg BD, & Ecosprin150 mg od, Atorvastatin 10 mg hs, Ramipril 2.5 mg, for CAD & standing, & Urimax D 0.4 mg for B P H. My prostate gland size/vol is 44.16 ml. My blood sugar, blood pressure, lipid profile & calcium labs reports are normal. whether I can stop to take Calcium & vitamin E, Atorvastatin, Ramipril Medicines from today now in view to remove my heavy Constipation & back side whole skin dryness & itching condition. Thank you.