Mild conc lvh enlargement and thickening (hypertrophy) of the walls of your heart's main pumping chamber (left ventricle). Left ventricular hypertrophy can develop in response to some factor ? such as high blood pressure or a heart condition ? that causes the left ventricle to work harder. As the workload increases, the muscle tissue in the chamber wall thickens, and sometimes the size of the chamber itself also increases. The enlarged heart muscle loses elasticity and eventually may fail to pump with as much force as needed.