HI lybrate-user, As per your history disease of GI Junction with Liver metastasis, I Presume you want to say about GE junction, Post 2 lines of Chemotherapy
and progressive. The overall picture is not happy, it will be advisable to meet the surgical Oncologist
if I assume the ascites and pleural effusion is not disease related. If Ascites and Pleural effusion are disease related, which is more a possibility as per case scenario, there are limited options. One vital option would be targeted therapy, with Herceptin if not already instituted in case of Her 2 +ve cancer
. Overall with limited information, I feel the picture is quite gloomy. Having said that, ultimate power is GOD, so don't lose hope and Keep fighting. Good luck.