The primary use of Metoprolol is to treat hypertension and angina pectoris. It is also prescribed as a preventive measure to treat myocardial infarction, atrial fibrillation, flutter, and symptomatic treatment of hypertrophic subaortic stenosis.
Metoprolol is prescribed to patients to improve heart function and control blood flow through the vessels. The drug helps in the treatment of hypertension, that is, high blood pressure and angina, that is, chest pain.
Metoprolol effectively blocks the action of a few body chemicals that occur naturally in the body. The medicine can be taken either before or after a meal. The dosage of the drug depends on the severity of the condition. The doctor may increase dosage as per requirement.
Over dosage of Metoprolol should be avoided. In case of accidental overdosage emergency medical care should be acquired. Patients with certain medical problems are generally not advised to take this drug. The medicine is not recommended for patients who have coronary heart disease or blood circulation issues.
If you have suffered a heart attack recently Metoprolol may not be the best option for you. Inform your doctor before consuming the drug, if you have clinical conditions like-
- Kidney issues
- Liver problems
- Thyroid disorder
- Any allergies.
Because Metoprolol leads to confusion, one should avoid driving in order to avoid accidents. Alcohol should also be avoided when on the drug because liquor can intensify its side effects. The dosage of Metoprolol may vary from 100mg to 450mg.
Some medicines which may affect the action of Metoprolol are prazosin, terbinafine, bupropion etc. Thus, you should inform your doctor about any medicines that you are currently taking before starting the medicine. In case of a missed drug dose, it should be taken as soon as possible. However, avoid taking the missed dose along with the next dose as it may lead to complications.
Common side effects of this medicine are as follows:
How long is the duration of effect?The effect lasts for 3 to 6 hours upon oral administration. This increases to 5 to 6 hours upon intravenous infusion.
What is the onset of action?The effect of Metoprolol (primary constituent of Metoprolol) can be observed within an hour of oral administration. When given in the form of an intravenous infusion, the action starts in 20 minutes.
Are there any pregnancy warnings?This medicine is not recommended for use during pregnancy unless absolutely necessary. Consult your doctor about the potential benefits and risks before deciding to take this medicine. Even if the medicine is used, the dose should be as low as possible and should be discontinued at least 2-3 days before delivery.
Is it habit forming?No habit forming tendencies were reported.
Are there any breast-feeding warnings?This medicine has not known to cause any alarming side effects on the infant as the amount passed through milk is very less. However, caution should be exercised and the medicine be used only when the potential benefits outweigh the risks associated. Consult your doctor before taking this medicine.
Is It safe with alcohol?This medicine is found to be unsafe if consumed with alcohol.
Is it safe to drive while on this medicine?This medicine affects the consciousness of the patient and also the alertness of the patient. Do not drive if you are taking this medicine.
Does this affect kidney function?This medicine is found to be safe if used in patients with kidney disease. Adjustment of dose is not needed.
Does this affect liver function?Caution must be taken in patient with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking this medicine.
Are there any missed dose instructions?Take the missed dose as soon as you remember. However, the missed dose can be skipped if it is almost time for the next scheduled dose.
Are there any overdose instructions?An overdose of this medication can cause some serious effects on the heart, blood vessels, and nerve conduction. Report the incidence as soon as possible so that medical intervention can begin. Supportive measures like Gastric lavage and symptomatic treatment might be required based on severity.
Below is the list of medicines, which contains Metoprolol as ingredient
This medication works by blocking the beta receptors sites in the heart, blood vessels, and lungs. This results in inhibition of epinephrine resulting in relaxed blood vessels. Thus pressure is lowered and blood flow to the heart is improved.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
AmlodipineReport the usage of either of these medicines to the doctor. A dose adjustment and safety monitoring may be required in such cases. Symptoms like headache, fainting, decrease in pulse or heart rate should be reported to the doctor.
DiltiazemReport the use of either of these medicines to the doctor. Dose adjustment and safety monitoring may be required in such cases. Symptoms like fatigue, headache, fainting, an increase in weight, chest pain should be reported to the doctor.
AminophyllineReport the usage of either of these medicines to the doctor. Dose adjustments and safety monitoring may be required in such cases. Contact your doctor if you experience nausea, vomiting, lack of sleep, and uneven heartbeat. Do not discontinue the usage of any medicine without consulting your doctor.
ErgotamineReport the use of either of these medicines to the doctor. A dose adjustment and safety monitoring may be required in such cases. Symptoms like cold and numb hands and feet, muscle pain and weakness, severe headache etc. should be reported to the doctor.
OthersThis medicine must not be concomitantly used along with the following:
- CYP2D6 enzyme substrate
- Clonidine:Hypertensive crisis after or during withdrawal of either agent.
- Drugs which slow AV conduction (digoxin): effects may be additive with beta-blockers.
- Fluoxetine may inhibit the metabolism of Metoprolol resulting in cardiac toxicity.
- Glucagon: Metoprololmay blunt the hyperglycemic action of glucagon.
- Hydralazine may enhance the bioavailability of Metoprolol.
- Insulin and oral hypoglycemics: Metoprolol may mask tachycardia from hypoglycemia.
- Metoprolol reduces antipyrine's clearance by 18%.
- NSAIDs (ibuprofen, indomethacin, naproxen, piroxicam) may reduce the antihypertensive effects of beta-blockers.
- Oral contraceptives may increase the AUC and Cmax of Metoprolol.
- Salicylates may reduce the antihypertensive effects of beta-blockers.
- Sulfonylureas: Beta-blockers may alter response to hypoglycemic agents.
- Verapamil or diltiazem may have synergistic or additive pharmacological effects when taken concurrently with beta-blockers; avoid concurrent I.V. use.
Interaction with DiseaseAsthma to your doctor so that Metoprolol can be substituted with another medication.
Heart BlockMetoprolol should not be used in patients having a heart block greater than first degree. However, it can be used in this case if a pacemaker is present to correct the disorder.
DiabetesMetoprolol should be administered with caution in patients suffering from diabetes or a condition where blood sugar level is likely to get low. You should consult a doctor if any symptom indicating a lowered blood sugar level is suspected while using this medicine. liver disease. Suitable dose adjustment and safety monitoring are advised in such cases.Glaucoma. A change in the dose of current Glaucoma medicine may be required. In some cases, your doctor may advise the use of another medicine in place of a beta blocker.
High Cholesterol And FatMetoprolol should be administered with caution in a patient having high levels of cholesterol and fats in their body. Suitable dose adjustment and safety monitoring may be required in such cases.
Interaction with Food
Ques: Does Metoprolol cause weight gain?
Ques: How long does Metoprolol take to work?
Ques: Is there any food or drink I need to avoid while taking Metoprolol?
Ques: Do I need to avoid playing sports while taking Metoprolol?
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