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Mefenamic acid

Prescription vs.OTC: Prescription by Doctor required
Last Updated: November 28, 2019

Mefenamic acid is generally prescribed to women for the treatment of menstrual pain. The drug works best on moderate to mild pain. Take the drug as per the directions given by your doctor. Known to be an NSAID, the drug blocks the action of substances that cause inflammation in the body. This drug only treats inflammation and discomfort, not the disease that results in such symptoms.

Doctors do not advice the use of Mefenamic acid if you allergic to any component present in it. It is also not safe for consumption in patients who have just had a bypass operation or suffer from kidney issues, stomach problems and ulcers. Women who are in their late stages of pregnancy are also not prescribed this drug.

Mefenamic acid is meant for oral consumption and should be taken either without food or with food in case you have stomach issues.

Some common side effects of the medicine that you may experience are pain in the stomach, nausea and diarrhea. Most people do not experience any serious side effects of the drug. In case you do develop heartburn, indigestion, itchy skin, appetite loss, rashes, pain in the lower back or see blood in your urine get in touch with your doctor as soon as possible.

Keep in mind some precautionary measures before you start using the drug. For instance, avoid driving or indulging in any risky activity so as to prevent accidents. This is primarily because Mefenamic acid can cause drowsiness as well as dizzy spells. Excessive smoking, alcohol consumption or taking high doses of the drug for an extensive time period can worsen its side effects. Thus, it is best that you avoid drinking and smoking while taking this medicine. Take the dosage as instructed by your doctor to avoid any complications.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.
  • Allergy

    This medicine is not recommended for use if you have a known history of allergy to mefenamic acid or other medicines of the NSAID class.
  • Other Allergic Conditions

    This medicine is not recommended for use if you have a allergic condition like asthma, urticaria, or any other allergic condition.
  • Coronary Artery Bypass Surgery (Cabg)

    This medicine is not recommended for use if you have undergone coronary artery bypass surgery recently.
  • Diarrhoea

  • Constipation

  • Bloating

  • Headache

  • Dizziness

  • Ringing Or Buzzing In The Ears

  • Blurred Vision

  • Weight Gain

  • Shortness Of Breath

  • Swelling Of Face, Lips, Eyelids, Tongue, Hands And Feet

  • Peeling And Blistering Of Skin

  • Fast Heartbeat

  • Unusual Bleeding

  • Yellow Colored Eyes Or Skin

  • Difficulty In Swallowing

  • Bloody And Cloudy Urine

  • Excessive Tiredness

  • How long is the duration of effect?

    The effect of this medicine lasts for an average duration of 4-6 hours.
  • What is the onset of action?

    The effect of this medicine can be observed within 20-30 minutes of administration.
  • Are there any pregnancy warnings?

    This medicine is not recommended for use in pregnant women unless potential benefits outweigh the risks associated. Contact your doctor before using this medicine. It should not be used during the third trimester of pregnancy.
  • Is it habit forming?

    No habit forming tendencies were reported.
  • Are there any breast-feeding warnings?

    Use of this medicine in breastfeeding women is not recommended as the amount passing through the milk and its effect on the infant is unknown. Your doctor may prescribe a safer alternative in such cases.
  • Missed Dose instructions

    Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose then the missed dose can be skipped.
  • Overdose instructions

    Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms may include rashes on the skin, confusion, pain in the chest, blurred vision etc. Immediate medical attention is needed if an overdose is confirmed.
  • India

  • United States

  • Japan

Below is the list of medicines, which contains Mefenamic acid as ingredient

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This medicine works by blocking the action of Cyclo-oxygenase (COX) which is involved in the production of Prostaglandins. Your body produces prostaglandins as a retort to certain diseases and injury. It works by preventing the production of prostaglandins and thereby reduces pain and inflammation.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Disease

    Asthma

    Use of this medicine should be avoided in patients suffering from aspirin-sensitive asthma. It should be used with caution in patients suffering from other forms of asthma or broncho-obstructive disorders.

    Fluid Retention And Edema

    This medicine should be used with caution in patients with pre-existing fluid retention disorder. Fluid retention can be attributed to other conditions like hypertension, heart failure etc. Therapy with this medicine should begin only after these risk factors are ruled out.

    Gastrointestinal Toxicity

    This medicine or other NSAIDs should be taken after consulting a doctor especially if the intended duration is longer than a month. Any symptom indicating ulceration and bleeding like chronic indigestion, appearance of coffee colored dry blood in stools or vomiting of blood should be reported immediately.

    Skin Rash

    This medicine can cause these fatal skin allergies without any warnings. Signs and symptoms like rashes, hives, fever or other allergic symptoms should be reported without any delay. This condition requires immediate medical intervention.

    Impaired Kidney Function

    This medicine should be taken after consulting a doctor if you are having a kidney disease. Suitable adjustment in dosage and monitoring of kidney functions is required in such situations. It should not be used if the impairment is severe.

    Impaired Liver Function

    This medicine should be used with caution in patients having an impairment of liver function. Suitable dose adjustments and monitoring of liver function are recommended in such cases.
  • Interaction with Alcohol

    Ethanol

    Avoid or limit the uptake of alcohol while using this medicine. Contact your doctor immediately if blood is observed in the stool, cough, or vomit.
  • Interaction with Lab Test

    Diazo test for urinary bile

    Report the use of this medicine before undergoing the diazo test for determination of urinary bile content. This medicine can potentially yield a false positive result.
  • Interaction with Food

    Food

    Information not available.
  • Interaction with Medicine

    Glimepiride

    Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring to safely use these medicines together. Signs and symptoms like a headache, dizziness, nausea, fast heartbeat, increased hunger etc. should be reported to the doctor.

    Methotrexate

    Report the use of either of the medicine to the doctor. Since the risk of toxicity and adverse effects are significantly high, you may require a dose adjustment and more frequent clinical monitoring while using them together.

    Propranolol

    Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring to safely use these medicines together. Do not stop the use of any medicine without consulting your doctor.

    Ramipril

    Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring to safely use these medicines together. Signs and symptoms like swelling, nausea, vomiting, muscle cramps, confusion, and weakness should be reported to the doctor.

    Tacrolimus

    Report the use of either of the medicine to the doctor. You may require a dose adjustment and more frequent monitoring to safely use them together. Do not stop the use of any medicine without consulting your doctor.

    Warfarin

    Report the use of either of the medicine to the doctor. You may require a dose adjustment based on the clotting time. Contact your doctor immediately if you observe the presence of blood in the urine, stools, cough etc.

    Furosemide

    Report the use of either of the medicine to the doctor. You may require a dose adjustment and certain tests to safely use these medicines together. It is recommended to drink plenty of water while taking these medicines.

    Aspirin

    Report the use of either of the medicine to the doctor. You may require a dose adjustment based on the clotting time. Contact your doctor immediately if you observe the presence of blood in the urine, stools, cough etc.

    Ketorolac

    These medicines are not recommended for use together as the risk of adverse effects are significantly high. Your doctor may prescribe an alternative that is safer for use.

    Immune globulin (intravenous)

    The risk of kidney damage is significantly high if this medicine is taken with an intravenous dose of immune globulin. You may require a dose adjustment and frequent monitoring to safely use these medicines together.

    Spironolactone

    Report the use of either of the medicine to the doctor. You may require a dose adjustment and certain tests to safely use these medicines together. Do not stop the use of any medicine without consulting your doctor.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Table of Content
About Mefenamic acid
What are the uses of Mefenamic acid
What are the contraindications of Mefenamic acid ?
What are the side effects of Mefenamic acid ?
Key highlights of Mefenamic acid
What are the dosage instructions?
Where is the Mefenamic acid approved?
Medicines containing Mefenamic acid
How does this medication work?
What are the interactions of Mefenamic acid ?