Choltran Oral Suspension
Choltran Oral Suspension, a bile acid sequestrant, is a strong ion exchange resin which binds bile within the alimentary canal and prevents its reabsorption. It forms insoluble complexes with bile acids and removes from them from the body during defecation. In order to compensate for the lost bile acids from the body, more plasma cholesterol gets converted to bile acids in the liver and hence reduces plasma cholesterol levels.
Choltran Oral Suspension is used to treat problems like hypercholesterolemia, pruritus (itching due to liver failure), post vagotomy diarrhoea, Clostridium difficile infections, post cholecystectomy syndrome, Crohn's disease, bile acid diarrhoea and other types of cholestasis. Choltran Oral Suspension is sometimes compounded with aquaphor and used for treating diaper rash in infants.
Choltran Oral Suspension is marketed as powder for oral ingestion, in 4g packets, or in larger containers and the dosage is 4 to 8g once twice daily. The maximum dosage is 24g per day.
Side effects of Choltran Oral Suspension include tarry stools, constipation, sudden loss in weight, stomach ache, bloating, belching, nausea, vomiting, indigestion, headache, dizziness, diarrhoea, femoral nerve pain, vertigo, muscle and joint pain, arthritis, osteoporosis, osteomalacia, urticaria (in cases of hypersensitivity), diuresis, hematuria, dysuria, asthma and others.
Increased Cholesterol Levels In Blood
Is It safe with alcohol?Interaction with alcohol is unknown. Please consult your doctor.
Are there any pregnancy warnings?Choltran oral suspension may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Are there any breast-feeding warnings?Unknown. Human and animal studies are not available. Please consult your doctor.
Is it safe to drive while on this medicine?There is no data available. Please consult doctor before consuming the drug.
Does this affect kidney function?There is no data available. Please consult doctor before consuming the drug.
Does this affect liver function?There is no data available. Please consult doctor before consuming the drug.
Are there any missed dose instructions?If you miss a dose of Cholestyramine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Choltran Oral Suspension acts as a bile acid sequestrant. It works by combining with the bile acids in the gastrointestinal tract, thereby preventing their reabsorption in the blood and thus reducing LDL cholesterol.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Medicine
Zydol 50Mg Suspension
LASIX 40MG/4ML INJECTION
VALOX 500MG TABLET CR
Cholestyramine-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:https://druginfo.nlm.nih.gov/drugportal/name/cholestyramine
Cholestyramine-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 9 June 2022].Available from:https://go.drugbank.com/drugs/DB01432
CHOLESTYRAMINE tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 9 June 2022].Available from:https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=CHOLESTYRAMINE
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