Post Exposure Prophylaxix (PEP) In HIV
Pep is required for all persons invo5 in providing medical and surgical services
No environmental transmission reported but pep is pep is required when they are exposed to -
potentially infectious body fluid e. G. Blood, semen, vaginal secretions, synovial, pleural, pericardial, peritoneal fluid, amniotic fluid. Any bodu fluid contaminated with" visible blood" considered" at risk"
exposure to body fluid considered" not at risk" e. G. Tears, sweat, urine, faeces, saliva, sputum and vomitus
Management of exp6 site
- do not panic
- wash wound and surrounding with soap and water
- rinse well
- do not scrub
- for not use antiseptic or skin washes
- splash of blood
- irrigate eyes with water or saine
- if using contact lens leave them in place while irrigating. Remove the contact lens and clean them after eyes is cleaned
- mouth: spit fluid immediately and rinse mouth thoroughly water/saline repeatedly
Pep is required within 72 hours of exposure
conslt nearest art center for selection of pep regime e. G.
1. Basic regime of 2 drug zidovudine 300 mg bd
- Stavudine 30 mg bd
- Lamivudine 150 mg bd
- pep in pregnancy
- Efavirenz is contrindicated in first trimestelr
- Indinavir is contrindicated prenatally
2 drug regime is recommended if third drug is required then use nelfinavir
arv prophylaxix - short term arv drugs is used to reduce hiv transmission from mother to infant
- all hivexposed infants should receive cotrimoxazole at 4-6 weeks of age
nevirapine prophylaxix
- mother- nov 200 mg at onset of labour
- baby- nvp syrup 2 mg / lg of body weight within 72 hours of delivery