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Stavudine

Prescription vs.OTC: Prescription by Doctor required

Stavudine is used along with a combination of a number of other medicines in order to treat the HIV disease. It is an antiviral medicine of the nucleoside analogue type. It is known to interfere with the production ability of virus, thereby inhibiting the growth and spread of disease. The Stavudine drug may not be administered to you if you are allergic to any ingredient of the drug, if you suffer from lactose intolerance, lactic acidosis or an enlarged liver. You must consult the doctor if you are pregnant, planning a pregnancy any time soon. You must make the doctor aware of any past diseases that you had such as liver, kidney or heart disorders. The medicine has to be provided with extreme caution if you suffer from obesity, have abnormal liver functions or other allergic reactions to the medicine. The medicine can be taken orally, with or without food as directed by the doctor. You must stay off alcohol, smoking, tobacco or caffeine during the course of the treatment as it may cause a number of health complications. It is important to take precautions to stop the spread of HIV through sexual contact, saliva or blood. Therefore do not share your belongings with others and use contraceptives like condoms to prevent HIV from being communicated to your sexual partner.

Information given here is based on the salt and content of the medicine. Effect and uses of medicine may vary from person to person. It is advicable to consult a HIV Specialist before using this medicine.

hiv infection

In addition to its intended effect, Stavudine may cause some unwanted effects too. In such cases, you must seek medical attention immediately. This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Is It safe with alcohol?

Interaction with alcohol is unknown. Please consult your doctor.

Are there any pregnancy warnings?

Stavir 30mg capsule may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Are there any breast-feeding warnings?

Unknown. Human and animal studies are not available. Please consult your doctor.

Is it safe to drive while on this medicine?

Patients may experience dizziness and/or somnolence, and they should avoid driving or operating machinery.

Does this affect kidney function?

Dose adjustment is required in patients with underlined renal diseases. Please consult your doctor.

Does this affect liver function?

There is no data available. Please consult doctor before consuming the drug.

Are there any missed dose instructions?

If you miss a dose of Stavudine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Below is the list of medicines, which contains Stavudine as ingredient
Alkem Laboratories Ltd
Emcure Pharmaceuticals Ltd
Emcure Pharmaceuticals Ltd
Sun Pharmaceutical Industries Ltd
Sun Pharmaceutical Industries Ltd
Alkem Laboratories Ltd
Alkem Laboratories Ltd
Sun Pharmaceutical Industries Ltd
Macleods Pharmaceuticals Pvt Ltd
Emcure Pharmaceuticals Ltd
Hetero Drugs Ltd
Emcure Pharmaceuticals Ltd
Sun Pharmaceutical Industries Ltd
Stavudine works as a nucleoside reverse transcriptase inhibitor (NRTI) and by breaking down into its active metabolites when ingested. These metabolites inhibit the enzyme HIV-1 reverse transcriptase (RT) by competitively blocking the natural substrate and thus prevent viral DNA from growing.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

Interaction with Medicine

Valgaids 450Mg Tablet

Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

Popular Questions & Answers

She is hiv+ and taking anti retroviral therapy for past 4 years. She is taking tenofovir, lamvudine combination. Previously took stavudine, lamvudine. Now due to lipodystrophy buffalo hump over neck is visible restrictingher neck movements. Please suggest solution.

DNB in Psychiatry, completed course from Asha Hospital, Hyderbad
Psychiatrist, Salem
Hello sir, you please consult the psychiatrist as it is dependent on hiv infection. After going through your complete parameters you will have remedy for the same.

Hi, I am HIV positive (HIV 1) and on ART (Viraday) for last 8 months. Thanks to it my viral load is undetectable and cd 4 count is above 450. But I feel like my current medication is taxing me a lot and there are cheaper alternative like avonza and triomune available. Or should I continue with viraday for more improvement? I also know government provides free medication but in my state the availability of such treatment is not consistent and people are pushed to buy art from market. Please guide me.

MBBS, PGDHIVM (HIV Medicine)
General Physician, Delhi
Hi, I am HIV positive (HIV 1) and on ART (Viraday) for last 8 months. Thanks to it my viral load is undetectable and ...
All tablets mentioned by you are different. They have different combinations and and composition. How can you compare medicine having different composition. I want to give a info to all people on ART via this reply that NEVER and NEVER change your medication unless decided by your doctor. These are very prone for resistance and if changed without doctors recommendations, they might stop working or may even cause some problems. So don't do it. Kindly consult your Dr. for rest details. Thanks.
2 people found this helpful

Sir I am hbsag positive and my sgpt, sgot is normal I'm taking lamivir about 4 years. Is this ok. please suggest me.

MD - Homeopathy, BHMS
Homeopath, Vadodara
Sir I am hbsag positive and my sgpt, sgot is normal I'm taking lamivir about 4 years. Is this ok. please suggest me.
No it is not and it will never cure it.. Better take Homoeopathic treatment... As it can cure it...

Which milk supplement is good for kids? Junior horlicks/lil champs/pediasure/horlicks growth plus or any others.

Diploma in Child Health (DCH), MBBS
Pediatrician, Noida
Which milk supplement is good for kids? Junior horlicks/lil champs/pediasure/horlicks growth plus or any others.
As such if a child is having normal indian food then there is no need of a supplement at all but if child is not eating properly then first approach should be towards proper eating habits and not just to give supplements bcz no supplement can give you proper nutrition still if you want to give then they all have different nutritive value and you can give them alternatively.
5 people found this helpful

Hi, Please suggest. Junior horlicks and pediasure which one is best for children?

MBBS Bachelor of Medicine and Bachelor of Surgery, BCH, DNB - Training, PDCC - Pediatric Hepatology & Gastroenterology
Pediatrician, Gurgaon
Hi, Please suggest. Junior horlicks and pediasure which one is best for children?
Pediasure can be used as a meal like milk you may add 6 scoops in a glass of water and give once a day. Junior Horlicks is not used alone to be added in milk etc.
1 person found this helpful

Popular Health Tips

Post Exposure Prophylaxix (PEP) In HIV

MBBS, D.P.H
General Physician, Gurgaon
Post Exposure Prophylaxix (PEP) In HIV

Pep is required for all persons invo5 in providing medical and surgical services 
No environmental transmission reported but pep is pep is required when they are exposed to -

 potentially infectious body fluid e. G. Blood, semen, vaginal secretions, synovial, pleural, pericardial, peritoneal fluid, amniotic fluid. Any bodu fluid contaminated with" visible blood" considered" at risk"
 exposure to body fluid considered" not at risk" e. G. Tears, sweat, urine, faeces, saliva, sputum and vomitus

Management of exp6 site
- do not panic 
- wash wound and surrounding with soap and water 
- rinse well
- do not scrub
- for not use antiseptic or skin washes
- splash of blood 
- irrigate eyes with water or saine
- if using contact lens leave them in place while irrigating. Remove the contact lens and clean them after eyes is cleaned 
- mouth: spit fluid immediately and rinse mouth thoroughly water/saline repeatedly 

Pep is required within 72 hours of exposure 
 conslt nearest art center for selection of pep regime e. G. 

1. Basic regime of 2 drug zidovudine 300 mg bd 

2 drug regime is recommended if third drug is required then use nelfinavir
 arv prophylaxix - short term arv drugs is used to reduce hiv transmission from mother to infant
- all hivexposed infants should receive cotrimoxazole at 4-6 weeks of age
 nevirapine prophylaxix 
- mother- nov 200 mg at onset of labour 
- baby- nvp syrup 2 mg / lg of body weight within 72 hours of delivery
 

2 people found this helpful

How is Hiv Treatment ?

MD - General Medicine
Sexologist, Delhi
How is Hiv  Treatment ?

Hiv treatment is done by antiviral drugs, there are a number of antiviral drugs available in the market, usually HIV is treated with a combination of drugs, usually two to three drugs are used in treating HIV in the initial stage, we can change the combination of drugs according to the requirement of the patient. Drugs can be adjusted or increased if there is the resistance of HIV in the patient.

There are a number of compounds (about 22 in number) which have been formally approved (by us food and drug administration) for the treatment of HIV infections (aids). According to their point of intervention with the HIV replicative cycle, these compounds can be classified into 5 categories: (1) nrtis (nucleoside reverse transcriptase inhibitors): azidothymidine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine; (2) ntrtis (nucleotide reverse transcriptase inhibitors): tenofovir, administered as its oral prodrug form tdf (tenofovir disoproxil fumarate); (3) nnrtis (non-nucleoside reverse transcriptase inhibitors): nevirapine, delavirdine and efavirenz; (4) pis (hiv protease inhibitors): saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, lopinavir, atazanavir, fosamprenavir, tipranavir and darunavir; and (5) fis (fusion inhibitors): enfuvirtide. Starting from the drugs which are currently available for the treatment of aids, numerous combinations could be envisaged. Drug combinations are, in principle, aimed at obtaining synergism between the compounds (reasonably expected if they act by different mechanisms), while reducing the likelihood of drug resistance development. Such anti-hiv drug combination regimes were initiated about 10 years ago and have been generally referred to as haart (for highly active antiretroviral therapy). While haart originally consisted of a pill burden of twenty (or more) pills per day, this has been gradually diminished over the past few years, and, since July 2006, an all-in-one pill (teevir from myelin and virotrenz from ranbaxy sun pharma) has become available, which contains three anti-hiv drugs (tenofovir disoproxil fumarate 300 mg, emtricitabine200mg and efavirenz 600 mg) to be taken as a single pill only once daily. Given the information that has been acquired for the therapeutic use (efficacy, safety) of tenofovir disoproxil fumarate over the past five years, it would now seem mandatory to further consider the prophylactic use of tdf [and its combination with emtricitabine (truvada) and/or atripla], as a single daily pill to prevent HIV infection. New combinations of drugs are also available which include tenofovir 300 mg lamivudine 150 mg which is very new drugs.


Now a days we can treat patients who had sex with some sex worker or any male transgender or some unknown person and during sexual intercourse condom gets bursted, we can treat them if they come to us within 72 hours of direct contact, these medicines are called post-exposure prophylaxis (pep) drugs for hiv or prophylactic treatment for hiv, by using these drugs we can treat a patient and we can stop transfusion of hiv virus to the person.

Pep involves taking anti hiv drugs as soon as possible after having been exposed to unprotected sex with some sex worker or transgender of with homosexual prep is a new hiv prevention method in which people who do not have hiv infection take pills of medicine daily to reduce the risk of becoming infected with hiv virus, pep should be taken within 72 hours of exposure to unprotected sex before the virus has time to rapidly duplicate in your body, pep consists of 2-3 antiretroviral drugs taken for 28 days.

3 people found this helpful

Hiv Treatment

MD - General Medicine
Sexologist, Delhi
Hiv Treatment

HIV treatment is done by antiviral drugs, there are number of antiviral drugs available in the market, usually HIV is treated with combination of drugs, usually two to three drugs are used in treating HIV in initial stage, we can change the combination of drugs according to requirement of the patient. Drugs can be adjusted or increased if there is resistance of HIV in the patient.

There are number of compounds (about 22 in number) which have been formally approved (by the US Food and Drug Administration) for the treatment of HIV infections (AIDS). According to their point of intervention with the HIV replicative cycle, these compounds can be classified in 5 categories: (1) NRTIs (nucleoside reverse transcriptase inhibitors): azidothymidine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine; (2) NtRTIs (nucleotide reverse transcriptase inhibitors): tenofovir, administered as its oral prodrug form TDF (tenofovir disoproxil fumarate); (3) NNRTIs (non-nucleoside reverse transcriptase inhibitors): nevirapine, delavirdine and efavirenz; (4) PIs (HIV protease inhibitors): saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, lopinavir, atazanavir, fosamprenavir, tipranavir and darunavir; and (5) FIs (fusion inhibitors): enfuvirtide. Starting from the drugs which are currently available for the treatment of AIDS, numerous combinations could be envisaged. Drug combinations are, in principle, aimed at obtaining synergism between the compounds (reasonably expected if they act by different mechanisms), while reducing the likelihood for drug resistance development. Such anti-HIV drug combination regimens were initiated about 10 years ago and have been generally referred to as HAART (for highly active antiretroviral therapy). While HAART originally consisted of a pill burden of twenty (or more) pills per day, this has been gradually diminished over the past few years, and, since July 2006, a all-in-one pill (teevir from myelin and virotrenz from Ranbaxy sun pharma) has become available, which contains three anti-HIV drugs (tenofovir disoproxil fumarate 300 mg, emtricitabine200mg and efavirenz 600 mg) to be taken as a single pill only once daily. Given the information that has been acquired on the therapeutic use (efficacy, safety) of tenofovir disoproxil fumarate over the past five years, it would now seem mandatory to further consider the prophylactic use of TDF [and its combination with emtricitabine (Truvada) and/or Atripla], as a single daily pill to prevent HIV infection. New combinations of drugs are also available which include tenofovir 300 mg lamivudine 150 mg which are very new drugs.


Now a days we can treat patients who had sex with some sex worker or any male transgender or some unknown person and during sexual intercourse condom gets bursted , we can treat them if they come to us within 72 hours of direct contact, these medicines are called POST-EXPOSURE PROPHYLAXIS (PEP) drugs for HIV or prophylactic treatment for HIV, by using these drugs we can treat a patient and we can stop transfusion of HIV virus to the person.

PEP involves taking anti HIV drugs as soon as possible after having been exposed to unprotected sex with some sex worker or transgender or with homosexual PrEP is a new HIV prevention method in which people who do not have HIV infection take pills of medicine daily to reduce the risk of becoming infected with HIV virus ,PEP should be taken within 72 hours of exposure to unprotected sex before the virus has time to rapidly duplicate in your body, PEP consists of 2-3 antiretroviral drugs taken for 28 days.

10 people found this helpful

Saurabh Chaudhary Proves Nothing Is Impossible with Right Focus and Dedication!

MBBS Bachelor of Medicine and Bachelor of Surgery
General Physician, Faridabad
Saurabh Chaudhary Proves Nothing Is Impossible with Right Focus and Dedication!

The 16 years old Saurabh Chaudhary from Kalina village, Meerut has turned into a national sensation. By winning gold in 10 meters Air Pistol, he has created a 240.7 points record at the Asian Games 2018, being held in Jakarta & Palembang, Indonesia.

Saurabh Chaudhary was followed by Tomoyuki Matsuda in the 2nd position, who is the 2010 World Champion from Japan, and Abhishek Verma in the 3rd position, a 29-year-old Indian, who made a debut in this Asian Games.

After winning the Gold, Saurabh said that he did not feel any kind of pressure, as he was there just to compete and do his best. He also added that he has trained hard for this and has been giving good results constantly because of that.

Saurabh Chaudhary’s Achievements

This is not Saurabh Chaudhary’s only achievement. He has been setting records since he started his shooting career. He recently made a junior record of 243.7 points in Shooting at the ISSF Junior World Cup 2018, held at Suhl, Germany. He also qualified for the Youth Olympics Games with a record and a gold medal. Saurabh is also training hard for Olympics 2020, which is going to be held in Tokyo, Japan.

His History

Saurabh Chaudhary belongs to a farmer family. It all started with liking for toy guns. Saurabh started training for shooting just few years back in 2015 at Amit Sheoran's Academy, located in Binauli, which is near Baghpat and around 53 kms from Meerut.

As told by Saurabh, he likes to spend time with his parents and also likes farming a lot. Whenever he is free, he spends time with his family and in farming.

How Saurabh Achieved Gold in the Asian Games 2018?

Saurabh Chaudhary was able to achieve all the name and fame because of his dedication and rigorous training. He has been training regularly since 2015 to be where he stands right now. But, how was it all possible at a tender age of 16 years?

Teenage is a very critical stage of a person’s life. The brain tends to lose focus and concentration at this age very much, and one needs to be dedicated enough to reach such a stringent goal. Saurabh’s dedication towards shooting paid off and finally the whole nation knows him for his achievement.

How to gain Concentration and Focus during Teenage?

Even though there is no lack of motivation or lack of resources - concentrating, focusing, and staying determined towards a goal becomes difficult for curious teenage minds. Although curiosity is good, staying focused on their goal can take them places.

Here are some basic tips on staying focused and dedicated towards a goal:

  • Eat healthy, Stay fit: A fit body is a gateway to a healthy and focused mind. And for this, including healthy food in diet, such as green veggies and fruits is necessary.

  • Make a routine and Plan the day ahead: Teenagers should follow a routine to carry out daily activities. Also, before sleeping, planning things out for the next day helps a lot.

  • Do not waste time: Time is the most valuable thing, and one must not waste it on distractions. Occasional games and sports breaks are necessary though.

  • Rest is necessary for teens: It’s always a bad idea to constantly be engaged with activities. Taking a break to rest, and sometimes a nap helps to gather energy back. After the break, starting with practice is the best way to go.

  • Get Ample Sleep: Dedication should not come at the cost of sleep deprivation. A teenager needs around 8-10 hours of sleep every day.

Saurabh Chaudhary has put up a milestone for all the teenagers out there with not only his talent but also with the level of focus and concentration to achieve his goals. This proves that anything is achievable with enough dedication.

3 people found this helpful

What Happens During A Routine Dental Check Up

MDS - Orthodontics & Dentofacial Orthopaedics, Post Graduation Certicate In Clear Aligner Therapy, Post-Graduate Certificate in Oral Implantology (PGCOI) , Certificate In Advanced Endodontics,Laser Dentistry, BDS
Dentist, Gurgaon
What Happens During A Routine Dental Check Up

No one likes going to a dentist. People fear a toothache, let alone the treatment. Because of this, a lot of people end up in the dentist's chair only when the pain is unbearable and it is too late to save the tooth. Just like we have a routine health check up for the rest of our body, our teeth too need to be looked at by a dentist at regular intervals to spot that cavity right when it starts. A regular visit can also allow a quick clean up to keep your teeth shining white.

Here's what to expect during a routine dental check up:

  1. They'll check your history: Before you actually get to the dentist's chair, your dentist will want to know your entire health background. This is done either by you filling out a detailed form that the receptionist gives you or a junior dentist filling a medical record sheet after asking you questions. You'll specially be asked questions about any pain or symptoms you might be experiencing in your teeth and other things like medications, diabetes, arthritis, pregnancy etc. Each of these problems can have a direct impact on your dental treatment, hence revealing them to your practitioner in advance is very important. Also, be sure to discuss any concerns or anxiety you are experiencing. Most dentists know how to put their patient at ease. All it'll take is a quick chat to put you at ease.
  2. You'll get a cleaning: Just like the car gets a good wash before the mechanic can have a look, your teeth will get a good scrub before your dentist can address any problem areas. Cleaning involves scraping off built up plaque and tartar that collects above and below the gum line before flossing between and around every tooth to remove any plaque or food particles that are clinging on. You may also get a final shiny finish for your pearly whites at the end of the cleaning session.
  3. Your teeth will be examined: Your dentist will now use a metal probe with a small angled mirror to see behind and between teeth and gums, as well as check for the softening of tooth enamel and dentin. If you have a cavity or anything deeper, this is when it will surface. Once the doctor identifies a problem, they suggest the next course of action.
  4. You may get an X-ray: If the doctor finds a problem that needs fixing, he may ask you to take an X-ray to find out how deep the decay is. You'll be asked to bite down on a piece of plastic while the X-ray machine is placed against your cheek. Where possible, you can check if your doctor can do a digital X-ray which emits 90% less radiation.
  5. Results and advice: Based on your X-ray results and overall medical condition, the doctor may recommend various procedures to remove your existing decay and prevent new ones.
3111 people found this helpful
Table of Content
About Stavudine
When is Stavudine prescribed?
What are the side effects of Stavudine ?
Key highlights of Stavudine
What are the dosage instructions?
Medicines containing Stavudine
How does medicine works?
What are the interactions for Stavudine ?