Nevilast 150 Mg/30 Mg/200 Mg Tablet

Hepatitis B and C are considered the world’s chronic viral hepatitis which kills a huge number of people every year. Even though it accounts for massive suffering as well as early death, it could only attract relatively less national and international attention. While the deaths caused by tuberculosis, malaria and HIV/AIDS have reduced to a great extent since the early 2000s, deaths stemming from hepatitis B and C are rising at a fast pace. It kills around 1 million people across the world.

Can medicine help in the treatment of hepatitis B and C?
There are numerous FDA approved medications available for the treatment of Hepatitis B and C. Here are some of the best medicines for this, but before you take them, you must consult an expert who can evaluate your symptoms and recommend the right drugs for you.

Medicines for Hepatitis B:

1. Entecavir: It is used in chronic hepatitis B virus infection and can treat active viral replication.
2. Lamivudine: It is used for treating chronic hepatitis B which is associated with Hepatitis B viral replication along with active liver inflammation.
3. Adefovir dipivoxil: This is used for the treatment of the disease in children below the age 12 years.
4. Interferon alpha 2B: It can be used for young children aged 1 year who are affected by the disease along with compensated liver disease.
5. Pegylated interferon: It is used for the treatment of adult patients with HBeAg positive and negative chronic hepatitis. If the patient has compensated liver disease along with liver inflammation and evidence of viral replication, then this medicine is usually given.
6. Telbivudine: When there is chronic hepatitis with adult patients along with persistent elevations in ALT and AST or previously active disease, this medicine may have to be administered.
7. Tenofovir alafenamide: It is indicated for the treatment of chronic hepatitis B virus infection in adults with compensated liver disease.

Medicines for Hepatitis C:

1. Ribavirin: This medicine can be used in combination with other medicines for chronic hepatitis C virus infection. Ribavirin can be utilized for compensated liver disease in patients who have not been treated with interferon alpha.
2. Daclatasvir: This is an NS5A replication complex inhibitor which is often given with sofosbuvir for the treatment of patients with chronic HCV genotype 3 infection.
3. Sofosbuvir and Velpatasvir: The combination of these two medicines is used for the treatment of adult patients with chronic genotype 1 to 6 without any infection. It may be used in combination with ribavirin in patients with compensated or decompensated cirrhosis.
4. Ledipasvir: A fixed-dose of a combination of hepatitis C virus inhibitor and Ledipasvir can be employed in the treatment of hepatitis genotype 1 infection in adults.

Both in the cases of Hepatitis B and C, it is important to diagnose the infection early. Prevention and cure are possible with precautionary measures and prescribed medications.

In case you have a concern or query you can always consult an expert & get answers to your questions!

HIV treatment is done by antiviral drugs, there are number of antiviral drugs available in the market, usually HIV is treated with combination of drugs, usually two to three drugs are used in treating HIV in initial stage, we can change the combination of drugs according to requirement of the patient. Drugs can be adjusted or increased if there is resistance of HIV in the patient.

There are number of compounds (about 22 in number) which have been formally approved (by the US Food and Drug Administration) for the treatment of HIV infections (AIDS). According to their point of intervention with the HIV replicative cycle, these compounds can be classified in 5 categories: (1) NRTIs (nucleoside reverse transcriptase inhibitors): azidothymidine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine; (2) NtRTIs (nucleotide reverse transcriptase inhibitors): tenofovir, administered as its oral prodrug form TDF (tenofovir disoproxil fumarate); (3) NNRTIs (non-nucleoside reverse transcriptase inhibitors): nevirapine, delavirdine and efavirenz; (4) PIs (HIV protease inhibitors): saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, lopinavir, atazanavir, fosamprenavir, tipranavir and darunavir; and (5) FIs (fusion inhibitors): enfuvirtide. Starting from the drugs which are currently available for the treatment of AIDS, numerous combinations could be envisaged. Drug combinations are, in principle, aimed at obtaining synergism between the compounds (reasonably expected if they act by different mechanisms), while reducing the likelihood for drug resistance development. Such anti-HIV drug combination regimens were initiated about 10 years ago and have been generally referred to as HAART (for highly active antiretroviral therapy). While HAART originally consisted of a pill burden of twenty (or more) pills per day, this has been gradually diminished over the past few years, and, since July 2006, a all-in-one pill (teevir from myelin and virotrenz from Ranbaxy sun pharma) has become available, which contains three anti-HIV drugs (tenofovir disoproxil fumarate 300 mg, emtricitabine200mg and efavirenz 600 mg) to be taken as a single pill only once daily. Given the information that has been acquired on the therapeutic use (efficacy, safety) of tenofovir disoproxil fumarate over the past five years, it would now seem mandatory to further consider the prophylactic use of TDF [and its combination with emtricitabine (Truvada) and/or Atripla], as a single daily pill to prevent HIV infection. New combinations of drugs are also available which include tenofovir 300 mg lamivudine 150 mg which are very new drugs.

Now a days we can treat patients who had sex with some sex worker or any male transgender or some unknown person and during sexual intercourse condom gets bursted , we can treat them if they come to us within 72 hours of direct contact, these medicines are called POST-EXPOSURE PROPHYLAXIS (PEP) drugs for HIV or prophylactic treatment for HIV, by using these drugs we can treat a patient and we can stop transfusion of HIV virus to the person.

PEP involves taking anti HIV drugs as soon as possible after having been exposed to unprotected sex with some sex worker or transgender or with homosexual PrEP is a new HIV prevention method in which people who do not have HIV infection take pills of medicine daily to reduce the risk of becoming infected with HIV virus ,PEP should be taken within 72 hours of exposure to unprotected sex before the virus has time to rapidly duplicate in your body, PEP consists of 2-3 antiretroviral drugs taken for 28 days.

If an HIV infection, treatment is primarily aimed at preventing evolve as long as possible and do not give way to the disease AIDS . In this case, the treatment is against HIV itself. If the emergence of AIDS and its accompanying diseases occur as a lung inflammation or bowel, treatment should include them. It is important to maintain a healthy lifestyle so that the immune system does not see further harmed. Many infected with HIV also have counseling and self-help centers with other affected. Drug Treatments Currently it has good information about certain steps in the single expansion of HIV infection. Thus, it has been possible to develop drugs that inhibit certain evolutions of cell infestation. HIV treatment is also called highly active antiretroviral therapy and its abbreviation is HAART. Specifically, this treatment includes the following medications: The entry inhibitors , which inhibit the entry of 'HIV virus' in human cells. VHI prevent adhesion of immune cells and / or dissolution of the viral envelope with the cell membrane (fusion). The excipient enfuvirtide eg prevents fusion. The reverse transcriptase inhibitor blocks a special top virus that can translate the genetic information of the virus (DNA) reverse transcriptase. This group of drugs includes, for example, substances such as lamivudine , the tenofovir or nevirapine . Another top virus, integrase, incorporating HIV DNA genetic information translated into immune cells. In this case, inhibitors of this enzyme, apply called integrase inhibitors . The drug raltegravir contains these integrase inhibitors. The protease inhibitors destroy other HIV enzyme, the HIV protease. If a cell is infected with HIV, forms a component of protein which could be born new HIV viruses. Protease HIV plays an important role in the composition of this protein. Inhibitors of this enzyme are involved in virus appear less capable of action in affected cells. Examples of protease inhibitors are drugs fosamprenavir , indinavir , nelfinavir, and ritonavir . Although 'AIDS' remains an incurable disease, it may be well with a combination therapy . This combination consists of at least three different drugs; usually several inhibitors of reverse transcriptase which are combined with a protease inhibitor.

 

Hiv treatment is done by antiviral drugs, there are a number of antiviral drugs available in the market, usually HIV is treated with a combination of drugs, usually two to three drugs are used in treating HIV in the initial stage, we can change the combination of drugs according to the requirement of the patient. Drugs can be adjusted or increased if there is the resistance of HIV in the patient.

There are a number of compounds (about 22 in number) which have been formally approved (by us food and drug administration) for the treatment of HIV infections (aids). According to their point of intervention with the HIV replicative cycle, these compounds can be classified into 5 categories: (1) nrtis (nucleoside reverse transcriptase inhibitors): azidothymidine, didanosine, zalcitabine, stavudine, lamivudine, abacavir and emtricitabine; (2) ntrtis (nucleotide reverse transcriptase inhibitors): tenofovir, administered as its oral prodrug form tdf (tenofovir disoproxil fumarate); (3) nnrtis (non-nucleoside reverse transcriptase inhibitors): nevirapine, delavirdine and efavirenz; (4) pis (hiv protease inhibitors): saquinavir, ritonavir, indinavir, nelfinavir, amprenavir, lopinavir, atazanavir, fosamprenavir, tipranavir and darunavir; and (5) fis (fusion inhibitors): enfuvirtide. Starting from the drugs which are currently available for the treatment of aids, numerous combinations could be envisaged. Drug combinations are, in principle, aimed at obtaining synergism between the compounds (reasonably expected if they act by different mechanisms), while reducing the likelihood of drug resistance development. Such anti-hiv drug combination regimes were initiated about 10 years ago and have been generally referred to as haart (for highly active antiretroviral therapy). While haart originally consisted of a pill burden of twenty (or more) pills per day, this has been gradually diminished over the past few years, and, since July 2006, an all-in-one pill (teevir from myelin and virotrenz from ranbaxy sun pharma) has become available, which contains three anti-hiv drugs (tenofovir disoproxil fumarate 300 mg, emtricitabine200mg and efavirenz 600 mg) to be taken as a single pill only once daily. Given the information that has been acquired for the therapeutic use (efficacy, safety) of tenofovir disoproxil fumarate over the past five years, it would now seem mandatory to further consider the prophylactic use of tdf [and its combination with emtricitabine (truvada) and/or atripla], as a single daily pill to prevent HIV infection. New combinations of drugs are also available which include tenofovir 300 mg lamivudine 150 mg which is very new drugs.

Now a days we can treat patients who had sex with some sex worker or any male transgender or some unknown person and during sexual intercourse condom gets bursted, we can treat them if they come to us within 72 hours of direct contact, these medicines are called post-exposure prophylaxis (pep) drugs for hiv or prophylactic treatment for hiv, by using these drugs we can treat a patient and we can stop transfusion of hiv virus to the person.

Pep involves taking anti hiv drugs as soon as possible after having been exposed to unprotected sex with some sex worker or transgender of with homosexual prep is a new hiv prevention method in which people who do not have hiv infection take pills of medicine daily to reduce the risk of becoming infected with hiv virus, pep should be taken within 72 hours of exposure to unprotected sex before the virus has time to rapidly duplicate in your body, pep consists of 2-3 antiretroviral drugs taken for 28 days.

Our ears are small in size, but ‘big’ in the work they do. Not only do they help us hear, but also help us maintain our body’s balance. They thus help us stand, walk, drive, you just name it.

Ears are also much bigger in size than they actually are. The part of the ear that we see on our head is only the external ear, there is a middle ear and an inner ear too, silently carrying out complex functions related to hearing and balance. The inner ear is the seat of balance. And this part is hit hard at the time of an ear infection.

Ear infections cause the Eustachian tubes – small tubes that connect the middle ear to the back of your throat – to become swollen and blocked due to excess mucus. As a result of this, fluid builds up and inflammation takes root in the middle ear, thereby causing pain.

Ear infections can be acute or chronic. Acute infections clear up in a few days, but chronic ones reoccur frequently. If not managed, chronic ear infections can cause permanent damage to the middle and inner ear.

Causes of Eustachian tube blockage are as follows:

1. Allergies
2. Sinus infection
3. Cold
4. Extreme production of mucus
5. Smoking
6. Infected adenoid, which is a tissue near your tonsils that traps harmful bacteria and viruses

There are a few risk factors associated with ear infections. It can be said that young children are more susceptible to these infections. This is because their Eustachian tubes are short and narrow. It has also been seen that infants who are bottle-fed have a higher incidence of ear infections than breastfed babies.

Other risk factors are:

1. Changes in altitude
2. Changes in climate
3. Exposure to tobacco smoke
4. Use of pacifiers

Symptoms of ear infections:

1. Pain or discomfort inside the ear
2. A prolonged feeling of pressure inside the ear
3. Pus-like ear drainage
4. Hearing loss

What is also important to know is that the symptoms of an ear infection come and go.

Symptoms can also occur in one or both ears. Chronic ear infection symptoms can be less noticeable than those of acute ear infections.

Hence, fever and ear ache should spur you to see a doctor. You should be extremely careful with babies younger than six months who have fever or ear infection symptoms.

Your doctor will diagnose an ear infection by checking if there is a draining of fluid from the middle ear, perforation in the eardrum or a collapsed eardrum.

Sometimes, ear infections can lead to the following serious complications:

1. Hearing loss
2. Speech or language delay in children
3. An infection in a skull bone called mastoiditis
4. Meningitis
5. Ruptured ear drum

In case you have a concern or query you can always consult an expert & get answers to your questions!