Cotrimoxazole Tablet

Manufacturer: Geno Pharmaceuticals Ltd
Medicine composition: Sulfamethoxazole, Trimethoprim
Prescription vs.OTC: Prescription by Doctor not required

Cotrimoxazole Tablet is used to fight against any kind of bacterial infections. It also prevents and treats Urinary Tract Infections. It prevents bacterial synthesis by slowing down growth and production.

Cotrimoxazole tablet helps in treating pneumonia, bronchitis, infections of the ear, and abdomen bacterial infections. Do not use this medication if you are allergic to any of the ingredients present in it. Before using this tablet tell your doctor if you have or are:

  • Taking any prescription drugs, non-prescription drugs, or other herbal and dietary pills and supplements.
  • Pregnant and/or breastfeeding.
  • Any upcoming surgeries.

Also let your doctor know your history of medical problems, pre-existing diseases and current health conditions. This medication should be taken in doses prescribed by the doctor. Dosage depends on conditions such as medical condition, diet, age, and counteraction with other medicines.

Cotrimoxazole Tablet is a prescription medicine and must be taken in the dose and duration prescribed by your doctor. To ensure better efficacy, it must be taken at a fixed time and after the meal. It must not be consumed in the dose, more than prescribed.

This medication must be taken only with the consultation of the Doctor. The tablet should not be taken empty stomach. It must be taken with the food with an adequate amount of water. Also, it must be taken at a fixed time to ensure better efficacy. Do not consume it more than the recommended dose.

This medication helps in treating the following problems in the human body:

  • Bacterial Infections

  • Hypersensitivity

Side effects of this medication which can be seen in a patient are:

  • Is It safe with alcohol?

    Consult your doctor before consuming alcohol.
  • Are there any pregnancy warnings?

    Women who are pregnant must consult doctor before using this medication.
  • Are there any breast-feeding warnings?

    Breastfeeding women must take medical help before consulting the doctor.
  • Does this affect kidney function?

    Caution to be advised in patients with impaired renal function.
  • Does this affect liver function?

    Caution must be taken in patient with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking it.
  • Is it safe to drive while on this medicine?

    It is not known whether this medicine affect the patients ability to drive. If you experience any symptoms affecting your consciousness, it is advised to avoid driving.
  • Are there any missed dose instructions?

    The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.
  • Are there any overdose instructions?

    Contact the doctor in case of overdose.

This tablet causes inhibition of the enzymatic alteration of pteridine and p-aminobenzoic acid (PABA) into dihydropteroic acid. It competes with PABA for combining with dihydrofolate synthetase. This is an intermediate of the tetrahydrofolic acid (THF) synthesis. After Trimethoprim combines to dihydrofolate reductase it brings about inhibition of dihydrofolic acid (DHF) reduction into tetrahydrofolic acid (THF). Tetrahydrofolic acid is an important predecessor to thymidine synthesis and hindrance with the synthesis of pathway brings about inhibition of bacterial DNA synthesis.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Lab Test

    May interfere with Jaffé alkaline picrate reaction assay for creatinine resulting in over-estimations of ~10% in the range of normal values; decreased effect with PABA or PABA metabolites of drugs (ie, procaine, proparacaine, tetracaine).
  • Interaction with Medicine

    Decreased effect with PABA or PABA metabolites of drugs (ie, procaine, proparacaine, tetracaine); cyclosporine levels may be decreased Increased effect/toxicity of oral anticoagulants, phenytoin, oral hypoglycemic agents, hydantoins, uricosuric agents, methotrexate when administered with sulfonamides Increased toxicity of sulfonamides with diuretics, indomethacin, methenamine, probenecid, and salicylates
  • Interaction with Food

    May cause folic acid deficiency, supplements may be needed.
  • Interaction with Disease

    Use with caution in patients with impaired renal or hepatic function or with possible folate deficiency. Maintain adequate fluid intake to prevent crystalluria. It should not be used for group A beta-hemolytic streptococcal infections

Ques: What is Cotrimoxazole Tablet?

Ans: Cotrimoxazole Tablet has Sulfamethoxazole and Trimethoprim as active elements present in it. This medicine performs its action by killing or slowing the growth of sensitive bacteria.

Ques: What are the uses of Cotrimoxazole Tablet?

Ans: Cotrimoxazole Tablet is used for the treatment and prevention from conditions such as Urinary tract bacterial infections and Respiratory tract bacterial infections.

Ques: What are the Side Effects of Cotrimoxazole Tablet?

Ans: Side effects include Nausea, Vomiting, Skin rash and Allergic reaction.

Ques: What are the instructions for storage and disposal Cotrimoxazole Tablet?

Ans: Cotrimoxazole Tablet should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

Ques: Can I stop taking Cotrimoxazole Tablet when my symptoms are relieved?

Ans: Do not stop taking this drug if you start feeling better as doing so can result in recurring symptoms. It is vital to complete the full course of medication to get the most out of this drug and to treat the infection completely.

Ques: What if I don't get better after using the Cotrimoxazole Tablet?

Ans: It is important to visit a doctor and tell him/her if you do not see any improvement in your medication condition even after taking this drug. Your doctor might recommend some other alternative medication or alter the dose in such a case.

Ques: Can the use of Cotrimoxazole Tablet cause diarrhea?

Ans: Diarrhea is one of the most common side effects of this medication. This is because this medicine basically works by killing the harmful bacteria and sometimes it interferes with the functioning of good bacteria which leads to diarrhea.

Ques: How long does Cotrimoxazole Tablet take to work?

Ans: It takes about a few days for this drug to start working, however, you would start feeling better just after taking this drug. Take this drug for the duration prescribed by the doctor to cure the infection completely.

Ques: Can I take Cotrimoxazole Tablet if I am pregnant?

Ans: Do not take this drug if you are pregnant. Consult a doctor to know a substitute of this drug.

Ques: How does Cotrimoxazole Tablet function?

Ans: The drug inhibits the production of folic acid, a compound that assists in the growth of bacteria in the body.
Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Cotrimoxazole Tablet
What are the uses of Cotrimoxazole Tablet
What are the contraindications of Cotrimoxazole Tablet ?
What are the side effects of Cotrimoxazole Tablet ?
Key highlights of Cotrimoxazole Tablet
What are the dosage instructions?
How does this medication work?
What are the interactions of Cotrimoxazole Tablet ?
FAQs about Cotrimoxazole Tablet