Cotrimoxazole Tablet

Cotrimoxazole Tablet is used to fight against any kind of bacterial infections. It also prevents and treats Urinary Tract Infections. It prevents bacterial synthesis by slowing down growth and production.

Cotrimoxazole tablet helps in treating pneumonia, bronchitis, infections of the ear, and abdomen bacterial infections. Do not use this medication if you are allergic to any of the ingredients present in it. Before using this tablet tell your doctor if you have or are:

• Taking any prescription drugs, non-prescription drugs, or other herbal and dietary pills and supplements.
• Pregnant and/or breastfeeding.
• Any upcoming surgeries.

Also let your doctor know your history of medical problems, pre-existing diseases and current health conditions. This medication should be taken in doses prescribed by the doctor. Dosage depends on conditions such as medical condition, diet, age, and counteraction with other medicines.

Cotrimoxazole Tablet is a prescription medicine and must be taken in the dose and duration prescribed by your doctor. To ensure better efficacy, it must be taken at a fixed time and after the meal. It must not be consumed in the dose, more than prescribed.

This medication must be taken only with the consultation of the Doctor. The tablet should not be taken empty stomach. It must be taken with the food with an adequate amount of water. Also, it must be taken at a fixed time to ensure better efficacy. Do not consume it more than the recommended dose.

This medication helps in treating the following problems in the human body:

• Bacterial Infections

• Hypersensitivity

Side effects of this medication which can be seen in a patient are:

• Nausea

• Vomiting

• Skin Rash

• Allergic Reaction

• Is It safe with alcohol?

  Consult your doctor before consuming alcohol.

• Are there any pregnancy warnings?

  Women who are pregnant must consult doctor before using this medication.

• Are there any breast-feeding warnings?

  Breastfeeding women must take medical help before consulting the doctor.

• Does this affect kidney function?

  Caution to be advised in patients with impaired renal function.

• Does this affect liver function?

  Caution must be taken in patient with liver disease. Adjustment of dose is needed. Kindly consult your doctor before taking it.

• Is it safe to drive while on this medicine?

  It is not known whether this medicine affect the patients ability to drive. If you experience any symptoms affecting your consciousness, it is advised to avoid driving.

• Are there any missed dose instructions?

  The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

• Are there any overdose instructions?

  Contact the doctor in case of overdose.

This tablet causes inhibition of the enzymatic alteration of pteridine and p-aminobenzoic acid (PABA) into dihydropteroic acid. It competes with PABA for combining with dihydrofolate synthetase. This is an intermediate of the tetrahydrofolic acid (THF) synthesis. After Trimethoprim combines to dihydrofolate reductase it brings about inhibition of dihydrofolic acid (DHF) reduction into tetrahydrofolic acid (THF). Tetrahydrofolic acid is an important predecessor to thymidine synthesis and hindrance with the synthesis of pathway brings about inhibition of bacterial DNA synthesis.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

• Interaction with Lab Test

  May interfere with Jaffé alkaline picrate reaction assay for creatinine resulting in over-estimations of ~10% in the range of normal values; decreased effect with PABA or PABA metabolites of drugs (ie, procaine, proparacaine, tetracaine).

• Interaction with Medicine

  Decreased effect with PABA or PABA metabolites of drugs (ie, procaine, proparacaine, tetracaine); cyclosporine levels may be decreased Increased effect/toxicity of oral anticoagulants, phenytoin, oral hypoglycemic agents, hydantoins, uricosuric agents, methotrexate when administered with sulfonamides Increased toxicity of sulfonamides with diuretics, indomethacin, methenamine, probenecid, and salicylates

• Interaction with Food

  May cause folic acid deficiency, supplements may be needed.

• Interaction with Disease

  Use with caution in patients with impaired renal or hepatic function or with possible folate deficiency. Maintain adequate fluid intake to prevent crystalluria. It should not be used for group A beta-hemolytic streptococcal infections