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Trimethoprim is an antibacterial which is available in the form of 100 mg tablets. It is administered orally. It is mainly used to deal with simple cases of urinary tract infections.

The usual oral dosage for adults is 100mg every 12 hours, or 200mg every 24 hours, for 10 days. Side effects of Trimethoprim include rashes, pruritus, and skin sensitivity especially on exposure to sunlight. However, these effects are mild and moderate, and appear 7 to 14 days after the beginning of the treatment. Trimethoprim may have an effect on the production of red blood cells, especially if taken in large doses, or over prolonged periods of time. Signs such as a sore throat, fever or pallor are symptoms of an overdose. Care should be taken while administering this medicine to patients with folate deficiency.

Since Trimethoprim may interfere with the metabolism of folic acid in the body, this medicine should be given to pregnant women only if the potential benefits of the medicine justify, and outweigh, the potential risk to the foetus. Similarly, caution must be taken while administering Trimethoprim to a lactating woman. This medicine is contraindicated in individuals that have hypersensitivity to it, are anaemic and have folic deficiency.

Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Internal Medicine Specialist before using this medicine.
  • Bacterial Infections

  • Is It safe with alcohol?

    Taking trimethoprim with alcohol may cause unpleasant side effects such as tingly feeling, nausea, and vomiting, fast heartbeats, warmth or redness under your skin, .
  • Are there any pregnancy warnings?

    Tmp 300mg tablet may be unsafe to use during pregnancy.
    Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
  • Are there any breast-feeding warnings?

    Unknown. Human and animal studies are not available. Please consult your doctor.
  • Is it safe to drive while on this medicine?

    There is no interaction between driving and consuming this drug. So dose alteration is not needed.
  • Does this affect kidney function?

    Caution to be advised in patients with impaired renal function.
  • Does this affect liver function?

    There is no data available. Please consult doctor before consuming the drug.
  • Are there any missed dose instructions?

    If you miss a dose of Trimethoprim, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Below is the list of medicines, which contains Trimethoprim as ingredient

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After getting combined to dihydrofolate reductase, the medicine brings about inhibition of dihydrofolic acid (DHF) reduction into tetrahydrofolic acid (THF). Tetrahydrofolic acid is an important predecessor to thymidine synthesis and hindrance with the synthesis of pathway brings about inhibition of bacterial DNA synthesis.

Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

  • Interaction with Medicine

    Zyvana 1Mg Tablet

Disclaimer: The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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Content Details
Written By
PhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child Care
Reviewed By
MBBS, Master in Healthcare Administration, Diploma in Occupational Health
General Physician
Table of Content
About Trimethoprim
What are the uses of Trimethoprim
What are the side effects of Trimethoprim ?
Key highlights of Trimethoprim
What are the dosage instructions?
Medicines containing Trimethoprim
How does this medication work?
What are the interactions of Trimethoprim ?