Last Updated: Aug 27, 2019
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Interstitial Cystitis: Treatment, Procedure, Cost and Side Effects

What is the Interstitial cystitis treatment? How is the Interstitial cystitis treatment done? Who is eligible for the treatment? (When is the treatment done?) Who is not eligible for the treatment? Are there any side effects? What are the post-treatment guidelines? How long does it take to recover? What is the price of the treatment in India? Are the results of the treatment permanent? What are the alternatives to the treatment?

What is the Interstitial cystitis treatment?

Interstitial cystitis is a type of chronic pain that affects the bladder. Its treatment includes lifestyle changes, procedures, and medications. There is no cure for interstitial cystitis. Treatments can improve symptoms. Medications may include ibuprofen, pentosane, poly sulfate or amitriptyline. There are mainly six lines of treatments for this interstitial cystitis. Dietary changes can also lead to sufficient amount of improvement in symptoms for many patients suffering from interstitial cystitis. Pharmacological options which can aid in treating Interstitial cystitis are:- non- steroidal anti-inflammatory drugs , trycyclic antidepressants, antihistamines and pentosan. Bladder distention, electrical nerve stimulation and surgery are also done as a treatment to Interstitial Cystitis. Surgery is the last line treatment when other options have failed to succeed. There are some specialized physical therapies like exercises which can help to provide relief to the patients.

How is the Interstitial cystitis treatment done?

The six line of treatments include- first line of treatment: patient education, self care, stress management; second line of treatment- physical therapy, oral medications, bladder instillations; third line of treatment- treatment of Hunner’s ulcers, hydrodistention ; fourth line treatment- neuromodulation; fifth line treatment- cyclosporine A, botulinum toxin; sixth line of treatment-surgical intervention . Physical therapist can assist in relieving the associated pain through various physical exercises. Exercises help to improve muscle tenderness, restrictive tissues or muscle abnormalities in pelvic floor. Drugs like ibuprofen, aspirin, naproxen help to reduce associated inflammation; amitriptyline or imipramine help to reax the bladder muscles and reduce pain; loratadine help to reduce urinary urgency; pentosane helps to restore epithelial cells of the bladder and also protect surrounding tissues from irritation. Dimethyl sulfoxide is given by way of a catheter with regular treatments for six to eight weeks followed by maintenance doses as needed. Simulation of sacral nerves may help to reduce urinary urgency. TENS help to relieve pain and reduce frequency of urination by increasing muscular control. Bladder distention is useful in certain situations like after a cystoscopy. Surgery procedures like Fulguration is used to burn ulcers causing severe pain in bladder, resection cuts around ulcer for their removal. Bladder augmentation replaces the damaged section of bladder with connective tissue from the colon.

Who is eligible for the treatment? (When is the treatment done?)

Patients suffering from Interstitial cystitis need to undergo the necessary treatment. If a person is undergoing symptoms like chronic pain of the bladder, feeling the need to urinate right away, need to urinate right away, burning sensation in urethra, pain with sex etc, then it is safe to enter the treatment to check the cause of the symptoms. Everyone if not affected by any other diseases or are having some restrictions are eligible for the treatments and medications. Patients should consult doctor and check their eligibility to undergo the appropriate treatment.

Who is not eligible for the treatment?

If any patient is suffering from any grave and serious disease before hand then it is better to inform the doctor before starting any medications because certain drugs show serious side effects which may worsen the patient’s condition further .

Are there any side effects?

Some evidences have been found which conclude that the long term oral antibiotics, bladder instillation of Bacillus Calmette-Gurin and bladder instillation of resiniferatoxin are harmful. Interstitial cystitis can lead to stiffening of bladder wall and reduce bladder capacity. The chronic pain and interrupted sleep as a consequence of interstitial cystitis cause emotional stress and lead to depression state. Tricyclic antidepressants have side effects like sleepiness, dry mouth and weight gain. There are some pain killers which can be taken during interstitial cystitis which have been proved to be addictive. Cyclosporine A has serious side effects like uncontrollable trembling, muscle or joint pain and enlarged gums. Pentosan polysulfate sodium has side effects like hair loss, gastrointestinal symptoms and increased liver function tests. Common side effects of Amitriptyline are fatigue, dry mouth, decrease in blood pressure and weight gain.

What are the post-treatment guidelines?

The treatments for interstitial cystitis are long term and are helpful in removing all the symptoms effectively. Interstitial cystitis is not curable. Certain foods can be avoided which can affect interstitial Cystitis like tomatoes, citrus fruits, coffee and chocolate. Other restrictions are like avoiding spicy foods, carbonated water and alcoholic drinks.

How long does it take to recover?

This Interstitial Cystitis is not curable. Treatment can be helpful but this condition cannot be cured. This chronic disease can last for years or can be lifelong. Sometimes interstitial cystitis is seen recurring in some cases. This can be effectively treated by using suitable treatment methods. The doctors will prescribe medications and instructions which can help to prevent the recurrence of Interstitial Cystitis after the initial treatment.

What is the price of the treatment in India?

Interstitial cystitis is a costly disease associated with comorbidities. There are a number of hospitals across India providing treatment to Interstitial cystitis and the cost varies depending upon the method chosen to treat the condition and on the health condition of the patient.

Are the results of the treatment permanent?

This condition is not curable and can last lifelong but the symptoms can be treated and can also be prevented to return by appropriate medications.

What are the alternatives to the treatment?

There are some alternatives to the treatments mentioned earlier- like simple changes to diet and life style lead to considerable improvement in symptoms. Eating whole, fresh, unrefined food. Include fruits and vegetables and whole grains. Avoid sugar, dairy products, refined foods, coffee, chocolates, alcohol, citrus fruits, tomato, carbonated drinks. Some complementary therapies have been proved to be beneficial for many patients such as- acupuncture, hypnosis and thiele massage. Herbal medicines too can be used for treatment which have no side effects if used at suggested doses like Gotu kola taken 30 mg standardized extract triterpenses 3 times per day. Homeopathy treatments may also be effective. As chronic pain is an isolating experience generally psychological support can also prove to be beneficial for a patient’s treatment. Some behaviour changes are also helpful like avoiding anything which can lead to flare-ups.

Transcutaneous electrical nerve stimulation

Safety: Medium

Effectiveness: High

Timeliness: Medium

Relative Risk: Medium

Side Effects: Medium

Time For Recovery: Very High

Price Range: Rs.500-Rs. 10000

Popular Questions & Answers

I'm 26 year old female. I had unprotected sex with my bf 1 month ago. He got uti 1 week after that. But I had no symptoms before or after that. Still I took azithromycin 1g and cefixime 400 mg on my doctor friends advice. But now my bf again got uti symptoms and i'm feeling burning sensation around vagina after I urinate although we are using protection every time now. Do I need to take antibiotics course again?

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This time it's better that both of you go for urine r/m & culture senstivity testing done & start antibiotics based upon reports only else there are high chances of getting resistance to microrganisms & you might land up hospitalsation & requiring...
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Respected, sir/madam can I usually take alkaline citrate syrup, because I always urge to urinate even when bladder was empty and after complete urinate few drops still flow down, when I urge to pee I feel gas and stomach pain, and also when I drink little more water immediate I urge to poop, please advice me.

MBBS, CCEBDM, Diploma in Diabetology, Diploma in Clinical Nutrition & Dietetics, Cetificate Course In Thyroid Disorders Management (CCMTD)
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Hello, thanks for the query. I have seen the information given. From the description given it appears you are having a problem of enlarged prostate. Please tell me why do you take that alkaline liquid (citralka or some such preparation ), because ...

Hii, I am nikita suffering with recurrent vaginal infection since 4/5 months. Actually I was delivered on october 23 threw cs and I am also a practitioner at my own set up in a short town. Thats why I started seatings very early then after I got a scanty brown discharge (may be lochia) two times after one and half month later in between a prephase of 15 days I consulted with my consultant surgeon as she said it may be an urinary infection you can take tablet martifur 100 mg b.d and I got relief. Then in mid of january I get uti again and I took the pills orr intake of fluids then got relief again, after a short period of 15 days I feels itchy vagina with milky white thick fluid then I take tablet fluka 150 mg stat and flagyl 400 mg bid for 5 days along with cream clo ect gm l/a twice and higher fluids then again I feel better, and the symptoms appears after a short duration then I again consulted with gyneco and she said remove your bartholin which I was having since 4/5 years but doesn't trouble me. As she advised I removed it on feb 9. When on day seventh with analgesic (ace-p sr) and antibiotic (cefuroxime200 mg) bid I feel pain and discharge at site even I took hot sitz and apply the povidine oint locally at site, I will go to her and after she was checked she said there is a infection you ma take tab. linezolid 600 with previous prescription. Because my stitches are broken thats why there is a discharge after a month I recovered from that, and a few days later there is itching over clitoris vulval lips and opening along vagina its very severe day by day then vaginal discharge became cudy and having some solid particles. Again I consulted with her and she suggest me to take sachet vanitizer for vaginal flora tablet fluconazole 150 mg o.d for 7 days continue and clotrimazole vaginal pessaries।.rapidly after all these I got relief gain and again after 15 days I get ihe infection symptoms even I am also practitioner as I said my brain wasn't working what is that and what to do. After a prolong treatment I didn't get relief. Urine routine examination is normal so I decided to go for hvs and it was also normal there is no pathogen. Then I consulted with an another going at my city. She suggest me to change antifungal and she prescribes capsule itamore 200 mg bid vaginal pessaries fantin alternate day for two days and ointment ornidazole+miconazole vaginally for 5 days. Get relief for few days wven after taking that and got the symptoms again now I go for pap smear and the reports are pending even I repeated urine routine there is pis cell 5-6 ans crystal 3-4 may be there is some chances of renal calculus so I go for a usg soon. Please suggest me what to do I am getting furstate due to this itching and burning sensation there is no odour in discharge I think some yeast infection it is. And when when I washed out I feels something like scum around the lips and vagina. Please help me. I am very thankful to you if someone suggest me something better thank you.

MBBS, MS, DNB, Fellowship in Reproductive Medicine
Gynaecologist, Bangalore
Get your sugar and hemoglobin levels, hiv status tested as you are getting recurrent infections. First give for urine culture and sensitivity test and high vaginal swab for culture and sensitivity at a well accredited lab. Treat accordingly and no...

Hi, I am having abdominal pain on left side along with back pain on same left side. I have visited doctor and they gave me medicines for uti (niftas 100). My question is I am planning for baby and this is my ovulation week. Can we still continue trying for baby while taking uti antibiotics medicines.

Fellowship in Reproductive Medicine & ART
IVF Specialist, Bangalore
Dear lybrate-user, in general, it is advised that during an ongoing active infection, it is better to get the infection treated, and then plan pregnancy, as health is more important. Also, some antibiotics are not to be taken when planning pregnan...

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