I've always had underlying depression issues. Years fine on Prozac. Then year or so ago I aware not sleeping, anxiety, anger, loss interest in everything. MD said Prozac maxed out for me so then effector (hated it almost suicidal!), cymbalta, lexipro, Zoloft and now supposed to start paxil. I can't keep doing this. I've lost my job, my friends can't listen anymore, I cry all the time and hide in bed 18 hours a day. What do I do? This is no way to live.
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You have been having depression of a relapsing nature and it seems to be more resistant to medications every next time. You might need a combinations of two or more group of antidepressants along with some augmenting agents too. Consult a psychiatrist personally, along with a family member or close friend. Do not stay alone. Always be with a friend or family member all the time. Ask for help and tell some one if you feel like having death wishes. If medicines are taking longer time to show effects and you continue to have deliberate self harm thoughts you may get admitted under a psychiatrist and start modified ects too. However that remains only one among all options. You have recovered from depression in past and you will surely improve this time too, sooner or later. Keep the faith. Take care.
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