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Overview

Ondicure Syrup

Manufacturer :  Grandcure Healthcare Pvt Ltd
Medicine Composition :  Ondansetron
Prescription vs OTC : Prescription by Doctor not required

About Ondicure Syrup

Ondicure Syrup belongs to the antiemetics drug group that is used for treating nausea as well as vomiting, caused by other medical treatments such as surgery, chemotherapy and radiation. This medicine will block the chemical serotonin from releasing in your gut and your central nervous system. This will prevent vomiting and nausea. Ondicure Syrup is available in four different forms that can be taken orally; tablet, disintegrating (dissolving) tablet, solution and film. It also comes in an IV (intravenous) form that can be injected to your body by a doctor. You can take it with food or without food.

Ondicure Syrup can be used alone as well as in a combination with other medicines for preventing vomiting and nausea that one experiences after a surgery, chemotherapy or radiation session. This medicine, belonging to the drug group named antiemetics, blocks serotonin, a natural substance present in the body that is known to cause vomiting. Ondicure Syrup is available both in tablet and liquid form. You can also take it in the IV form, when injected by a medical practitioner.

Your doctor must be informed if you are allergic to Ondicure Syrup as well as other medications that block serotonin, along with any other allergies that you have. He/ She must also know about your medical history and if you had problems such as liver disease, irregular heartbeat and stomach or intestinal problems in the past. Apart from that, you must also inform the doctor if you are under any medication for depression or any psychiatric disorder.

The dosage of Ondicure Syrup is decided after taking your medical condition into account and how responsive your body is to therapy. In case of children, the dose also depends on their weight and age. If you are undergoing chemotherapy, you need to take Ondicure Syrup orally half an hour before your treatment starts. In case of radiation, take it 1-2 hours before the procedure of treatment begins. For preventing nausea before a surgery, it is advised to take the medication an hour before your surgery. In case you miss a dose, you can take the medication once you remember it. If it is already time for the next dose, ensure that you do not take two doses to make up for the missed dose. Overdose of Ondicure Syrup can lead to severe constipation, faint spells or feeling light-headed.

The side effects of Ondicure Syrup can include dizziness, drowsiness, diarrhea, constipation and headache. These side effects are usually mild in nature and goes away in a few days or 1-2 weeks. You can consult your doctor if these symptoms remain for a long time. There are some serious side effects that Ondicure Syrup may have, which would require immediate medical supervision. They include:

  • Stiffness of the muscle / muscle spasms
  • Blurred vision or loss of vision temporarily
  • Fast heartbeat and sweating
  • Headache, accompanied with chest pain and a feeling of dizziness
  • Yellowing of the eyes or the skin
  • Hallucinating
  • An allergic reaction to the medication; the symptoms of which include fever, chills, rashes, difficulty in breathing and swelling of the lips, tongue, throat or face.

    What are the uses of Ondicure Syrup

    • Nausea Or Vomiting

      Ondicure Syrup helps in treating nausea and vomiting.

    • Nausea

      Ondicure Syrup treats nausea and vomiting in cancer chemotherapy patients.

    What are the contraindications of Ondicure Syrup ?

    • Allergy

      Avoid if the patient has a known allergy to Ondicure Syrup.

    • Apomorphine

      Avoid using Ondicure Syrup with Ondicure Syrup as it increases the risk of lightheadedness and loss of consciousness.

    What are the side effects of Ondicure Syrup ?

    Key highlights of Ondicure Syrup

    • How long is the duration of effect?

      This medicine is excreted primarily in urine and the effect of this medicine lasts for a duration of 12 to 28 hours.

    • What is the onset of action?

      The peak effect of Ondicure Syrup can be observed within 30 minutes for Intravenous and 2 hours for the tablet.

    • Are there any pregnancy warnings?

      Use of Ondicure Syrup is not recommended in pregnant women.

    • Is it habit forming?

      No habit forming tendency has been reported.

    • Are there any breast-feeding warnings?

      No clear data is available whether Ondicure Syrup is excreted through human breast milk. So, use of this drug is not recommended in breastfeeding women.

    What are the substitutes for Ondicure Syrup ?

    Below is the list of medicines, which have the same composition, strength and form as Ondicure Syrup , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any overdose instructions?

      Seek emergency medical attention or contact the doctor in case of overdose.

    • Are there any missed dose instructions?

      Missed dose should be taken as soon as possible. It is recommended to skip your missed dose, if it is the time for your next scheduled dose.

    How does this medication work?

    Ondicure Syrup works by blocking 5-HT3 receptors peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone.

      What are the interactions of Ondicure Syrup ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

        test
      • Interaction with Alcohol

        Alcohol

        Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
      • Interaction with Lab Test

        Lab

        Information not available.
      • Interaction with Medicine

        Apomorphine

        Use of Ondicure Syrup with Apomorphine is not recommended. Replacement of the drug should be considered under the doctor's supervision. Usage of other medicines should be reported to the doctor.

        Amiodarone

        Use of Ondicure Syrup with Amiodarone is not recommended as it may cause dizziness, lightheadedness, difficulty in breathing if these drugs are used together. Regular cardiac function tests are to be performed if the patient is having any heart disease. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.

        Amitriptyline

        If these drugs are used together, the patient may experience confusion, hallucination, changes in blood pressure, fever or excessive sweating. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Usage of other medicines should be reported to the doctor.

        Carbamazepine

        Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

        Phenytoin

        Patient's nausea and vomiting may not subside if these drugs are taken together. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.

        Cyclophosphamide

        The desired effect of cyclophosphamide will not be obtained if these drugs are concurrently taken. Under doctor's supervision, appropriate dose adjustments or replacement of the drug should be considered. Details of other drugs should be reported to the doctor.
      • Interaction with Disease

        Qt Prolongation

        Details of any heart disease, family history of an arrhythmia or any other drugs that cause QT interval prolongation (eg: Antipsychotics, Arrhythmia drugs) should be reported to the doctor. Regular cardiac function tests are to be performed if the patient is having any heart disease.

        Liver Disease

        Details of any liver disease (jaundice, hepatitis) or other drugs that may affect the liver (eg: TB drugs, HIV drugs) should be reported to the doctor. Regular liver function tests are to be performed if the patient is having any liver disease.
      • Interaction with Food

        Food

        Information not available.
      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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