Intalith Cr 450Mg Tablet
Intalith Cr 450Mg Tablet is an element that derives its name from the Greek word lithos meaning stone. It is used as a medicine most effectively in the treatment of bipolar disorder and other mental disorders such as poor cognitive skills, aggressive behavior, insomniac tendencies, hyperactivity.
On using Intalith Cr 450Mg Tablet you may experience certain side effects such as nausea, diarrhea, dizziness, fatigue, muscle weakness, mild tremors, frequent urge to urinate and thirst. These effects will decrease over time, however, if they should continue and worsen, seek medical aid right away.
Certain precautionary protocols that you are advised to follow before using Intalith Cr 450Mg Tablet includes notifying your doctor if you:
- Are pregnant or are planning to become pregnant. Intalith Cr 450Mg Tablet can prove to be fatal for the fetus if used during pregnancy.
- Are breastfeeding a baby. It can cause certain harmful side effects to the baby.
- Have a history of heart disease, thyroid or kidney disease.
- Are taking any prescriptive or over the counter drugs, herbal medications or dietary supplements.
- Have recently had a surgery or are scheduled for one soon. Lithium usage should be discontinued two weeks before your surgery.
The dosage for Intalith Cr 450Mg Tablet will be determined by your doctor as per the seriousness of your condition, overall health, gender and age. Usually the prescribed dosage for adults diagnosed with manic or bipolar disorder is about 1800 mg per day.
It should be taken in three sets of about 600 mg each in the morning, afternoon and night. The dose for children 12 years or older is also the same. Patients are advised to seek the help of your health care provider should you suspect drug overdose, or symptoms of Brugada, encephalopathy, diabetes or insipidus.Symptoms of overdose include sedation, confusion, tremors, joint pain, visual changes, seizures, coma. There is no specific antidote for lithium poisoning.
In the acute ingestion following initiation of essential overdose management, correction of fluid and electrolyte imbalances should be commenced. Hemodialysis and whole bowel irrigation is the treatment of choice for severe intoxications; charcoal is ineffective.
Take exactly as directed; do not change dosage without consulting prescriber. Do not crush or chew tablets or capsules. Maintain adequate fluid intake (2-3 L/day of fluids unless instructed to restrict fluid intake) especially in summer. Frequent blood test and monitoring will be necessary.
The primary use of this medication is as follows:
- mood disorder characterized by hyperactivity, elevation in mood and extreme enthusiasm.
Severe Heart DiseaseNot recommended in patients with known heart diseases.
How long is the duration of effect?The effect of this medicine lasts for an average duration of 2 to 3 days.
What is the onset of action?The effect of this medicine can be observed in 5 to 7 days.
Are there any pregnancy warnings?This medicine is not recommended for pregnant women.
Is it habit forming?No habit forming tendency has been reported
Are there any breast-feeding warnings?This medicine is not recommended in breastfeeding women.
Does this affect kidney function?Caution must be taken in patients with kidney disease. Dosing adjustment in renal impairment:
- Clcr 10-50 mL/minute: Administer 50% to 75% of normal dose.
- Clcr <10 mL/minute: Administer 25% to 50% of normal dose.
- Hemodialysis: Dialyzable (50% to 100%).
Does this affect liver function?Limited or no data available. Kindly consult your doctor before taking it.
Missed Dose instructionsTake the missed dose as soon as you remember. If itâ€™s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.
Overdose instructionsSeek emergency medical treatment or contact the doctor in case of an overdose.
Intalith Cr 450Mg Tablet is a mood-stabilising agent and although its exact way of working is unknown, it is believed to work by a number of ways including regulation of glutamate receptos, inhibition of the enzyme inositol monophosphatase or deactivation of the enzyme glycogen synthase kinase 3.
Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.
Interaction with Alcohol
Interaction with Lab Test
Interaction with Medicine
- Concurrent use of lithium with carbamazepine, diltiazem, fluoxetine, fluvoxamine, haloperidol, methyldopa, phenothiazines, TCAs, and verapamil may increase the risk for neurotoxicity; monitor.
- NSAIDs decrease renal lithium excretion leading to increased serum lithium concentrations; sulindac and aspirin may be the exceptions; monitor.
- Combined use of lithium and chlorpromazine may lower serum concentrations of both drugs; monitor.
- ACE inhibitors may increase the risk of lithium toxicity via sodium depletion; monitor.
- Lithium and MAOIs should generally be avoided due to use reports of fatal malignant hyperpyrexia.
- Losartan may reduce the renal clearance of lithium; monitor.
- Phenytoin may enhance lithium toxicity; monitor.
- Potassium iodide may enhance the hypothyroid effects of lithium; monitor.
- Combined use of lithium with sibutramine may increase the risk of serotonin syndrome; this combination is best avoided.
- Sodium bicarbonate and high sodium intake may reduce serum lithium concentrations via enhanced excretion; monitor.
- Thiazide diuretics increase serum lithium concentration via sodium depletion.
Interaction with Disease
DementiaThis medicine is not recommended in patients with dementia-related psychosis as it increases the risk of heart diseases like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.
Heart DiseasesThis medicine is not recommended in patients with heart disease. Inform the doctor if you have any heart disease before receiving this medicine. An alternate medicine should be considered based on the clinical condition.
HypothyroidismThis medicine may alter the thyroid levels, therefore, not recommended in patients with hypothyroidism. Check the thyroid levels before starting the treatment. The treatment should be discontinued if thyroid levels are low.
Interaction with Food
Ques: What is Intalith Cr 450Mg Tablet used for?
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Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.