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Ceftum 500 MG Tablet

Manufacturer :  Glaxosmithkline Pharmaceuticals Ltd
Medicine Composition :  Cefuroxime
Prescription vs OTC : Prescription by Doctor not required

About Ceftum 500 MG Tablet

Ceftum 500 MG Tablet is used for the treatment of susceptible infections of the lower respiratory tract, otitis media, urinary tract, skin and soft tissue, bone and joint, sepsis and gonorrhoea. It is an antibiotic drug that a part of the class of medicines called cephalosporin.

This broad-spectrum antibiotic is useful in treating a wide variety of infections that are caused by bacteria. This medicine specifically used for the treatment of infections caused by staphylococci, group B streptococci, H. influenzae (type A and B), E. coli, Enterobacter, Salmonella, and Klebsiella.

It is used in the treatment of conditions such as acute or chronic bronchitis, tonsillitis, Lyme disease, Chlamydia, gonorrhea, syphilis, pneumonia, laryngitis, sinusitis and urinary tract infections. This drug is also used to treat bacterial infections of the throat, cervix, pelvis, urethra, skin, middle ear and nasal passage.

Ceftum 500 MG Tablet works by creating a hostile environment for the bacteria to survive. It damages the cell walls of bacteria, prevents the growth of bacteria and therefore eliminates the bacterial infection.

Ceftum 500 MG Tablet intervenes in the bacteria’s process of forming cell walls. The cell walls of the bacteria are essential for their survival. The bacterial cell walls protect the contents of the cell from leaking out. This antibiotic damages the bond that keeps the cell wall in one piece.

Therefore, Ceftum 500 MG Tablet causes holes to appear in the cell wall, making it impossible for the bacteria to survive. In this way, by destroying bacteria and inhibiting the reproduction of bacterial cells, the antibiotic is effective in eliminating bacterial infections.

The risk of side effects increases if you take this medication while suffering from conditions like liver disorders, kidney problems, heart conditions, allergies, gastrointestinal diseases, phenylketonuria and diarrhoea caused by Clostridium difficile.

Since it might lead to negative reactions for these patients, you should consult with your doctor before starting a prescription of Ceftum 500 MG Tablet, if you are a:

  • Pregnant women
  • Breastfeeding mother
  • Children

You could have an allergic reaction from taking Ceftum 500 MG Tablet. An allergy to this anti-biotic will result in symptoms such as hives, rashes, swelling of the tongue, throat, face, hands or feet, itchiness and difficulty in breathing. If you experience any of these symptoms, you should discontinue the usage of this drug and contact a medical health professional immediately.

After acute overdose, most agents cause only nausea, vomiting, and diarrhea, although neuromuscular hypersensitivity and seizures are possible, especially in patients with renal insufficiency; many beta-lactam antibiotics have the potential to cause neuromuscular hyperirritability or seizures.

Hemodialysis may be helpful to aid in the removal of the drug from the blood but not usually indicated, otherwise most treatment is supportive or symptom directed following GI decontamination.

Take as directed, at regular intervals around-the-clock (with or without food). Chilling oral suspension improves flavor (do not freeze). Complete full course of medication, even if you feel better. Drink 2-3 L fluid/day. If diarrhea occurs, yogurt or buttermilk may help.

    What are the uses of Ceftum 500 MG Tablet

    • Bacterial Infections

    • Lower Respiratory Tract Infection

    • Otitis Media (Infection Of Ear)

    • Urinary Tract Infection

    • Skin And Soft Tissue Infections

    • Bone And Joint Infections

    • Sepsis

    • Gonorrhea And Associated Infections

    What are the contraindications of Ceftum 500 MG Tablet ?

    What are the side effects of Ceftum 500 MG Tablet ?

    Key highlights of Ceftum 500 MG Tablet

    • How long is the duration of effect?

      The effect of this medication lasts for a duration of 8 hours.

    • What is the onset of action?

      After administration, the medicine can be seen to start working within one or two hours.

    • Are there any pregnancy warnings?

      Pregnant women should not use this medication. Consult your doctor before using this medication. Potential benefits and risks involved should be given due consideration before administration.

    • Is it habit forming?

      The medication has not been reported to develop any habit-forming tendencies.

    • Are there any breast-feeding warnings?

      Women who are breastfeeding should avoid taking this medication as it can pass into the milk and affect the joints of the baby.

    • Is It safe with alcohol?

      Consumption of alcohol with this medicine does not cause any harmful adverse effects

    • Is it safe to drive while on this medicine?

      As this medicine is only prescribed to the patient who are hospitalized. Thus it is not relevant.

    • Does this affect kidney function?

      Only limited information is available regarding its use in patient with kidney disease. Kindly consult your doctor before taking this medication.

    • Does this affect liver function?

      Only limited information is available regarding its use in patient with liver disease. Kindly consult your doctor before taking this medication.

    What are the substitutes for Ceftum 500 MG Tablet ?

    Below is the list of medicines, which have the same composition, strength and form as Ceftum 500 MG Tablet , and hence can be used as its substitute.

    What are the dosage instructions?

    • Are there any missed dose instructions?

      In case you happen to miss your prescribed dose try to take it as soon as you recall it but should it already be time for the next dose then skip the earlier one.

    • Are there any overdose instructions?

      Seek medical aid right away on suspecting medication overdose.

    How does this medication work?

    The drug belongs to the second generation cephalosporins. It works as a bactericidal by inhibiting the bacterial cell wall synthesis by binding to the penicillin binding proteins which would inhibit the growth and multiplication of bacteria.

      What are the interactions of Ceftum 500 MG Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

      • Interaction with Alcohol

        It is not known as to how the medication might react upon interaction with alcohol and so it is advised that you seek permission of your doctor before deciding to consume it.

      • Interaction with Medicine

        • This medication is known to interact with Amikacin, Chloramphenicol, Ethinyl Estradiol, Cholera Vaccine and Furosemide.
        • Increased effect: High-dose probenecid decreases the clearance.
        • Increased toxicity: Aminoglycosides increase the nephrotoxic potential.
      • Interaction with Disease

        This medication can cause severe side effects in patients with a history of gastrointestinal disorders such as colitis, abdominal pain, diarrhoea and blood in stools. The medication can also pose risk to patients suffering from liver diseases; seizures and damaged kidney functioning as the medication can aggravate the condition. Therefore, it is advised that you notify your doctor of any pre-existing condition so that she or he may adjust the dose according to your case.

      • Interaction with Food

        This medicine may be taken with food, however, bioavailability is increased with food.

      FAQs about Ceftum 500 MG Tablet

      • Ques : What is Ceftum 500 MG Tablet?

        Ans : This medication belongs to the class of medicines called cephalosporin. It is a broad spectrum antibiotic is useful in treating a wide variety of infections that are caused by bacteria. The medicine kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive. It should be used with caution in patients with a history of kidney diseases.

      • Ques : What is the use of Ceftum 500 MG Tablet?

        Ans : This is used for the treatment and prevention from conditions and symptoms of diseases like pharyngitis/tonsillitis, acute bacterial otitis media, sinusitis, bronchitis, skin, and structure infection. Apart from these, this medicine can be used for the treatment of cystitis, pyelonephritis, Lyme disease, and gonococcal infection.

      • Ques : What are the side effects of Ceftum 500 MG Tablet?

        Ans : This is a list of possible side-effects which may occur due to the constituting ingredients of this medicine. This is not a comprehensive list. These side-effects have been observed and not necessarily occur. Some of these side-effects may be serious. These include Diarrhea, Chills, Headache, Itching of Vagina or Genital Area. Besides these, using this medicine can further lead to problems such as Diarrhoea, Abdominal Pain, Confusion, Fever, Constipation, Dizziness and Headache.

      • Ques : Can the use of Ceftum 500 MG Tablet cause Diarrhea?

        Ans : Yes, the use of this medicine can cause Diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea.

      • Ques : How long do I need to use Ceftum 500 MG Tablet before I see improvement of my conditions?

        Ans : The drug should be consumed, until the complete eradication of the disease. Thus it is advised to use, till the time directed by your doctor and moreover taking this medication longer than it was prescribed, can also cause inadequate effect on the patient. So please consult your doctor.

      • Ques : At what frequency do I need to use Ceftum 500 MG Tablet?

        Ans : The medicine is generally used twice or thrice a day, as the time interval upto which this medication has an impact, is around 4 to 8 hours, but it is not the standard frequency, for using this medication. It is advised to consult your doctor for the dosage, as the frequency also depends on the patient's condition.

      • Ques : Should I use Ceftum 500 MG Tablet Empty Stomach, Before Food or After Food?

        Ans : The salts involved in this medication react properly, if it is taken with the food. If you take it with an empty stomach, it may cause stomach upset. Please consult the doctor before use.

      • Ques : What are the instructions for storage and disposal of Ceftum 500 MG Tablet?

        Ans : The medicine contains salts which are suitable to store at room temperature and keeping this medication above or below that, can cause an inadequate effect. Protect it from moisture and light. Keep this medication, away from the reach of children. It is advised to dispose of the expired or unused medication, for avoiding its inadequate effect.

      • Ques : How long does Ceftum 500 MG Tablet take to work?

        Ans : The time taken by Ceftum 500 MG Tablet to show its action depends on the severity of the patient's condition. It also depends on the type of infection. However, in general, it takes about 48-72 hours.

      • Ques : Can you drink alcohol on Ceftum 500 MG Tablet?

        Ans : The consumption of alcohol should be limited during the course of medication as it can cause severe interactions that might prove fatal for some patients.

      • Ques : Can Ceftum 500 MG Tablet be taken on an empty stomach?

        Ans : This medication should not be consumed on an empty stomach as it can cause problems related to the stomach. You must only take it after food to enhance the effectiveness of the drug to cure the infection.

      • Ques : Can Ceftum 500 MG Tablet treat UTI?

        Ans : This medication can be helpful in managing urinary tract infection (UTI). However, it is effective only against uncomplicated cases of UTIs.


      • Cefuroxime- Drug Information Portal [Internet]. 2019 [Cited 23 April 2019]. Available from:

      • Cefuroxime: Uses, Side Effects, Dosage- Drugs Bank [Internet]. 2018 [Cited 26 April 2019]. Available from:

      • CEFUROXIME AXETIL - cefuroxime axetil tablet- Daily Med [Internet]. 2017 [Cited 23 April 2019]. Available from:

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.

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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Utsav NandwanaMBBS Bachelor of Medicine and Bachelor of Surgery, MBBSGeneral Physician

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