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Overview

Bendex Plus Tablet

Manufacturer :  Cipla Ltd
Medicine Composition :  Ivermectin, Albendazole
Prescription vs OTC : Prescription by Doctor not required

About Bendex Plus Tablet

Bendex Plus Tablet is used to cure cases of strongyloidiasis; which are roundworm infections. It also effectively treats head lice, scabies and river blindness. It falls under the group of drugs called anthelmintic. Bendex Plus Tablet works in the body by killing the developing worms and not the adult ones.

The common side effects that you maybe subject to experience on using Bendex Plus Tablet are vomiting, nausea, reduced appetite, bloating, abdominal pain, tiredness, constipation, drowsiness, lightheadedness, headache chest pain, shakiness.

If you are receiving treatment for onchocerciasis (river blindness) then you may have certain reactions for the first four days such as swollen eyes and swollen lymph, eye redness or itchiness, fever. However, if these allergic reactions continue, promptly notify your physician.

Before taking Bendex Plus Tablet discuss with your doctor these pre-existing conditions if any as a precautionary measure. These are:

  • If you are allergic to any ingredient contained within Bendex Plus Tablet.
  • If you are pregnant, are planning to become pregnant anytime soon, or are breastfeeding.
  • If you are taking prescriptive or non-prescriptive drugs, herbal products, or dietary supplements.
  • If you are suffering from more than one parasitic infection at the same time.
  • If you have asthma or a weak immune system.
  • If you are alcoholic.

The dosage of Bendex Plus Tablet will be according to your doctor’s prescription. It will be determined by your age, the severity of your condition, your medical history. The adult dose for curing onchocerciasis is 0.15 orally once in every 12 months and for treating strongyloidiasis 0.2 mg orally once.

Those with very severe fungal eye infection may need treatment every 3-6 months. In case of suspected drug overdose seek medical supervision immediately. If infected with strongyloidiasis, repeated stool examinations are required to document clearance of the organisms; repeated follow-up and retreatment is usually required in the treatment of onchocerciasis.

If infected with strongyloidiasis, repeated stool examinations are required to document clearance of the organisms; repeated follow-up and retreatment is usually required in the treatment of onchocerciasis.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the uses of Bendex Plus Tablet

    • Onchocerciasis

      Bendex Plus Tablet is used in the treatment of onchocerciasis which is a parasitic worm infection caused by Onchocerca volvulus transmitted through the bite of black flies characterized by skin itching and vision impairment.

    • Strongyloidiasis

      Bendex Plus Tablet is used in the treatment of strongyloidiasis which is an intestinal infection caused by a roundworm called Strongyloides stercoralis characterized by abdominal pain and diarrhea.

    • Scabies

      Bendex Plus Tablet is used in the treatment of scabies which is a skin infection caused by the mite called Sarcoptes scabiei characterized by itching and red rashes on the skin.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the contraindications of Bendex Plus Tablet ?

    • Allergy

      Not recommended in patients with known allergy to Bendex Plus Tablet.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the side effects of Bendex Plus Tablet ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Key highlights of Bendex Plus Tablet

    • How long is the duration of effect?

      The medicine stays in the body for an average duration of 2 to 3 days.

    • What is the onset of action?

      The peak effect of this medicine for treating onchocerciasis can be observed in 3 to 6 months and for strongyloidiasis in 3 months.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women unless necessary. The risk and benefits should be discussed with the doctor before receiving this medicine.

    • Is it habit forming?

      No habit forming tendencies were reported.

    • Are there any breast-feeding warnings?

      This medicine is known to excreted in breastmilk. It is not recommended in breastfeeding women unless necessary. Avoid direct contact of this medicine with the baby.

    • Is It safe with alcohol?

      It is found to be unsafe if consume alcohol with Bendex Plus Tablet.

    • Is it safe to drive while on this medicine?

      It does not affect the patients ability to drive.

    • Does this affect kidney function?

      Limited information available. Kindly consult your doctor before taking Bendex Plus Tablet.

    • Does this affect liver function?

      Limited information available. Kindly consult your doctor before taking Bendex Plus Tablet.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    Where is the Bendex Plus Tablet approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

    How does this medication work?

    This medication belongs to broad-spectrum antiparasitic agents. It works by acting on glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells. This effect increases the influx of chloride ions and causes hyperpolarization of nerve cells, resulting in paralysis and death of the parasite.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Derma before using this medicine.

      What are the interactions of Bendex Plus Tablet ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Consumption of alcohol is not recommended in patients receiving Bendex Plus Tablet. It may increase the concentration of this medicine and can cause skin rash, headache, dizziness, vomiting, diarrhea, and abdominal pain.
      • Interaction with Lab Test

        Information not available.
      • Interaction with Medicine

        Oxcarbazepine

        Inform the doctor if you are receiving oxcarbazepine, carbamazepine as these medicines decrease the effect of Bendex Plus Tablet. Any symptoms of the increase in the severity of infection should be reported to the doctor. The dose adjustments or an alternate medicine should be considered based on the clinical condition.

        Warfarin

        These medicines should be used with caution due to increase in the risk of bleeding. Any symptoms of unusual bleeding, blood in stools and vomiting, dizziness should be reported to the doctor. The dose adjustments or an alternate medicine should be considered based on the clinical condition.
      • Interaction with Food

        Information not available.
      • Interaction with Disease

        • Data have shown that antihelmintic drugs like Bendex Plus Tablet may cause cutaneous and/or systemic reactions (Mazzoti reaction) of varying severity including ophthalmological reactions in patients with onchocerciasis.
        • These reactions are probably due to allergic and inflammatory responses to the death of microfilariae.
        • Patients with hyper-reactive onchodermatitis may be more likely than others to experience severe adverse reactions, especially edema and aggravation of the onchodermatitis.
        • Repeated treatment may be required in immunocompromised patients (eg, HIV); control of extraintestinal strongyloidiasis may necessitate suppressive (once monthly) therapy.

      FAQs about Bendex Plus Tablet

      • Ques : What is Bendex Plus Tablet?

        Ans : Bendex Plus Tablet is a salt which performs its action by binding to the muscle and nerve cells of worms, causing their paralysis and death. This treats your infection. Bendex Plus Tablet is used to treat conditions such as Onchocerciasis, Strongyloidiasis, and Scabies.

      • Ques : What are the uses of Bendex Plus Tablet?

        Ans : Bendex Plus Tablet is a salt, which is used for the treatment and prevention of conditions such as Onchocerciasis and Strongyloidiasis. Apart from these, it can also be used to treat conditions like Scabies. The patient should inform the doctor about any ongoing medications and treatment before using Bendex Plus Tablet to avoid undesirable effects.

      • Ques : What are the Side Effects of Bendex Plus Tablet?

        Ans : Side effects include fever, muscle pain, skin rash, headache, dizziness, etc.

      • Ques : What are the instructions for storage and disposal Bendex Plus Tablet?

        Ans : Bendex Plus Tablet should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      • Ques : Is Bendex Plus Tablet effective?

        Ans : Yes, it is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition.

      • Ques : Is Bendex Plus Tablet available over the counter?

        Ans : No, it is not an OTC medicine. It can only be taken if prescribed by a doctor.

      • Ques : How does Bendex Plus Tablet work?

        Ans : This drug works by first paralyzing and then later killing the infection-causing organisms.

      • Ques : What if I forget to take a dose of Bendex Plus Tablet?

        Ans : If you forget a dose of this medication, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose.

      • Ques : Is Bendex Plus Tablet safe?

        Ans : Yes, it is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose.

      References

      • Ivermectin-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/ivermectin

      • Ivermectin-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 7 June 2022].Available from:

        https://go.drugbank.com/drugs/DB00602

      • Ivermectin tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 7 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=Ivermectin

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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