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Overview

Aripiprazole

Prescription vs OTC : Prescription by Doctor required

About Aripiprazole

Aripiprazole treats the symptoms of psychotic conditions such as schizophrenia, Tourette's disorder, bipolar I disorder, or symptoms of autistic disorder. If used together with other psychotic medicines, it can treat depressive disorders in adults. It only controls the symptoms but cannot be used to cure the disease.

This medication is an antipsychotic medication. It restores the balance of certain natural chemicals in the brain which decreases hallucinations and improves your concentration. This medicine controls your mood swings and decreases the frequency of mood swings.

You should not take this medicine if you are allergic to it, if you suffer from dementia or are breastfeeding. Before starting the medication, inform your doctor if you have any of the following conditions:

Some side effects like dizziness, nausea, excess saliva, vomiting, tiredness, blurred vision, headache, weight gain, constipation, and trouble sleeping may occur. Tell your doctor right away if you have any serious side effects, including fainting, depression, suicidal thoughts, restlessness, increased anxiety, shaking, muscle spasm, seizures, fever and persistent sore throat.

The dosage is based on your medical condition, response to treatment, age, and other medications you may be taking. Your doctor may direct you to start this medication at a low dose and gradually increase your dose. This is done to reduce the risk of side effects. Follow your doctor’s instructions carefully.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the uses of Aripiprazole

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the contraindications of Aripiprazole ?

    • Hypersensitivity

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the side effects of Aripiprazole ?

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    Key highlights of Aripiprazole

    • How long is the duration of effect?

      The effect of this medicine lasts for an average duration of 3 to 4 days.

    • What is the onset of action?

      The peak effect of this medicine can be observed in 1 to 3 hours for an immediate release tablet and 5 to 7 hours for an extended release tablet.

    • Are there any pregnancy warnings?

      This medicine is not recommended for pregnant women.

    • Is it habit forming?

      No habit forming tendency has been reported

    • Are there any breast-feeding warnings?

      This medicine is known to be excreted in human breast milk.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    What are the dosage instructions?

    • Missed Dose instructions

      If you miss a dose of this medication, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

    • Are there any overdose instructions?

      Seek emergency medical treatment or contact the doctor in case of an overdose.

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    Where is the Aripiprazole approved?

    • India

    • United States

    • Japan

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    Medicines containing Aripiprazole

    Below is the list of medicines, which contains Aripiprazole as ingredient

    Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

    How does this medication work?

    This medicine belongs is an antipsychotic agent that works as a partial agonist of dopamine D2 receptors and serotonin 5-HT1A receptors and relieves positive symptoms of schizophrenia and as a strong antagonist of serotonin 5-HT2A receptors which relieves the negative symptoms of schizophrenia.

      Information given here is based on the salt content of the medicine. Uses and effects of the medicine may vary from person to person. It is advisable to consult a Psychiatrist before using this medicine.

      What are the interactions of Aripiprazole ?

      Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction.

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      • Interaction with Alcohol

        Alcohol

        Consumption of alcohol with this medicine is not recommended as it can result in dizziness and difficulty in concentration. Avoid activities that need mental alertness like driving or operating machinery.
      • Interaction with Medicine

        Ketoconazole

        Azole antifungal agents like Ketoconazole and Itraconazole should be avoided when you are Aripiprazole due to the risk of increased concentrations of the medicine in the body which may cause dizziness, dry mouth, and irregular heartbeats. Inform the doctor if you are receiving these medicines when you are prescribed with this medicine and dose adjustments or an alternative medicine should be considered based on the clinical condition.

        Metoclopramide

        Concomitant use of these medicines is not recommended due to the increase the risk of abnormal body movements of face and limbs. Inform the doctor if you experience any symptoms of abnormal body movements, jerking of arms and legs.

        Antidiabetic medicines

        The desired effect of antidiabetic agents may not be achieved when taken with it. Regular monitoring of blood glucose levels is necessary. Inform the doctor if you develop any symptoms like excessive thirst, increased in the frequency of urination. Dose adjustments are to be made based on the clinical condition.

        Antihypertensives

        You may experience hypotensive effects like dizziness, lightheadedness if these medicines are used together. Regular monitoring of blood pressure is necessary. Appropriate dose adjustments or replacement of the medicine should be made under the doctor's supervision.
      • Interaction with Disease

        Dementia

        This medicine is not recommended in the patients with dementia-related psychosis as it increases the risk of heart diseases like heart failure and infectious diseases like pneumonia. An alternate medicine should be considered based on the clinical condition.

      FAQs about Aripiprazole

      • Ques : What is Aripiprazole?

        Ans : This medication treats the symptoms of psychotic conditions such as schizophrenia, tourette's disorder, bipolar I disorder, or symptoms of autistic disorder.

      • Ques : How long do I need to use Aripiprazole before I see improvement in my condition?

        Ans : This medication is to be taken till the time you see an improvement in your health conditions.

      • Ques : At what frequency do I need to use Aripiprazole?

        Ans : This medication should be taken in the dosage as prescribed by the doctor.

      • Ques : Should I use Aripiprazole empty stomach, before food or after food?

        Ans : This medication should be taken after food in a prescribed dosage.

      • Ques : What are the instructions for the storage and disposal of Aripiprazole?

        Ans : This medication should be kept in a cool dry place and in its original packaging. Make sure this medication remains unreachable to children and pets.

      References

      • Aripiprazole-Drug Information Portal [Internet].druginfo.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://druginfo.nlm.nih.gov/drugportal/name/aripiprazole

      • Aripiprazole-DrugBank Online [Internet].go.drugbank.com 2022 [Cited 2 June 2022].Available from:

        https://go.drugbank.com/drugs/DB01238

      • ARIPIPRAZOLE Tablet,solution-DailyMed [Internet].dailymed.nlm.nih.gov 2022 [Cited 2 June 2022].Available from:

        https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=all&query=ARIPIPRAZOLE

      Disclaimer : The information produced here is best of our knowledge and experience and we have tried our best to make it as accurate and up-to-date as possible, but we would like to request that it should not be treated as a substitute for professional advice, diagnosis or treatment.

      Lybrate is a medium to provide our audience with the common information on medicines and does not guarantee its accuracy or exhaustiveness. Even if there is no mention of a warning for any drug or combination, it never means that we are claiming that the drug or combination is safe for consumption without any proper consultation with an expert.

      Lybrate does not take responsibility for any aspect of medicines or treatments. If you have any doubts about your medication, we strongly recommend you to see a doctor immediately.
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      Content Details
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      Written ByDrx Hina FirdousPhD (Pharmacology) Pursuing, M.Pharma (Pharmacology), B.Pharma - Certificate in Nutrition and Child CarePharmacology
      Reviewed By
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      Reviewed ByDr. Garima SharmaMBBS, Master in Healthcare Administration, Diploma in Occupational HealthGeneral Physician
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