I have large and small acne in my face even in back also every place of face specially cheek has large acnes and other has small ,I noticed that in winter it getting more large one 's become small in summer but when winter came the start grew so how I can take care of it without taking any medicines bcuz I already tried to get rid from these from last 4 years and I tried every single medicine on it &how much glass of water I need to drink daily for clean face and how much time I needed for it (my. Father had also same problem so this is parental problem })