21 years old female of weight 70 kg with cervical lymph adenopathy diagnosed with chronic granulomatous lymphadenitis. She was on att prescribed by doc .on 10 days of usage she developed severe rash on whole body with fever .on stoppage they subsided doc has reduced the dose even then developed rash and fever .and next time on every usage she developed severe rash and fever even when individual tablets (single dose) are given for all h, r,z, e at present she stopped medication ethambutol 1800 mg pyrazinamide single tablet ke vachindulhi actual ga 3 tablets 750 mg isoniazid 300 mg rifampin 600 mg. What is the solution for this doc !pls reply.